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Volumn 360, Issue 16, 2009, Pages 1618-1627

Inhibitors of factor VIII in black patients with hemophilia

(14)  Viel, Kevin R a   Ameri, Afshin b   Abshire, Thomas C c   Iyer, Rathi V d   Watts, Raymond G e   Lutcher, Charles b   Channell, Cynthia c   Cole, Shelley A a   Fernstrom, Karl M c   Nakaya, Shelley f   Kasper, Carol K g,h   Thompson, Arthur R f   Almasy, Laura a   Howard, Tom E g,i,j  


Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8 INHIBITOR; ALLOANTIBODY; ANTIBODY; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING INHIBITOR; F8 PROTEIN, HUMAN;

EID: 64749096663     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa075760     Document Type: Article
Times cited : (163)

References (53)
  • 1
    • 0038383605 scopus 로고    scopus 로고
    • The epidemiology of inhibitors in haemophilia A: A systematic review
    • Wight J, Paisley S. The epidemiology of inhibitors in haemophilia A: a systematic review. Haemophilia 2003;9:418-435 (Pubitemid 36874391)
    • (2003) Haemophilia , vol.9 , Issue.4 , pp. 418-435
    • Wight, J.1    Paisley, S.2
  • 2
    • 8844263239 scopus 로고    scopus 로고
    • Pathogenic antibodies to coagulation factors. Part one: Factor VIII and factor IX
    • Lollar P. Pathogenic antibodies to coagulation factors. Part one: factor VIII and factor IX. J Thromb Haemost 2004;2:1082-1095
    • (2004) J Thromb Haemost , vol.2 , pp. 1082-1095
    • Lollar, P.1
  • 3
    • 0042626369 scopus 로고    scopus 로고
    • The incidence of inhibitor development according to specific mutations - and treatment?
    • Goodeve A. The incidence of inhibitor development according to specific mutations - and treatment? Blood Coagul Fibrinolysis 2003;14:Suppl 1:S17-S21.
    • (2003) Blood Coagul Fibrinolysis , vol.14 , Issue.SUPPL. 1
    • Goodeve, A.1
  • 4
    • 0030634299 scopus 로고    scopus 로고
    • Mutations in severe hemophilia A: Distribution within the factor VIII gene, origin and influence on inhibitor development
    • Oldenburg J, Grimm T, Becker J, Olek K, Brackmann HH, Schwaab R. Mutations in severe hemophilia A: distribution within the factor VIII gene, origin and influence on inhibitor development. Beitr Infusionsther Transfusionsmed 1997;34:224-230
    • (1997) Beitr Infusionsther Transfusionsmed , vol.34 , pp. 224-230
    • Oldenburg, J.1    Grimm, T.2    Becker, J.3    Olek, K.4    Brackmann, H.H.5    Schwaab, R.6
  • 7
    • 0029617930 scopus 로고
    • Haemophilia A: Mutation type determines risk of inhibitor formation
    • Schwaab R, Brackmann HH, Meyer C, et al. Haemophilia A: mutation type determines risk of inhibitor formation. Thromb Haemost 1995;74:1402-1406
    • (1995) Thromb Haemost , vol.74 , pp. 1402-1406
    • Schwaab, R.1    Brackmann, H.H.2    Meyer, C.3
  • 8
    • 0034994489 scopus 로고    scopus 로고
    • Incidence of factor VIII inhibitors in severe haemophilia: The importance of patient age
    • DOI 10.1046/j.1365-2141.2001.02828.x
    • Lorenzo JI, López A, Altisent C, Aznar JA. Incidence of factor VIII inhibitors in severe haemophilia: the importance of patient age. Br J Haematol 2001;113:600-603 (Pubitemid 32524377)
    • (2001) British Journal of Haematology , vol.113 , Issue.3 , pp. 600-603
    • Lorenzo, J.I.1    Lopez, A.2    Altisent, C.3    Aznar, J.A.4
  • 9
    • 30344434999 scopus 로고    scopus 로고
    • Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A
    • Goudemand J, Rothschild C, Demiguel V, et al. Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A. Blood 2006;107:46-51.
    • (2006) Blood , vol.107 , pp. 46-51
    • Goudemand, J.1    Rothschild, C.2    Demiguel, V.3
  • 10
    • 0000939750 scopus 로고
    • Increased frequency of inhibitors in African American hemophilia A patients
    • abstract
    • Addiego JE Jr, Kasper C, Abildgaard C, et al. Increased frequency of inhibitors in African American hemophilia A patients. Blood 1994;84:Suppl:239a. abstract.
    • (1994) Blood , vol.84 , Issue.SUPPL.
    • Addiego Jr., J.E.1    Kasper, C.2    Abildgaard, C.3
  • 11
    • 0031598278 scopus 로고    scopus 로고
    • Inhibitors occur more frequently in African-American and Latino haemophiliacs
    • Aledort LM, Dimichele DM. Inhibitors occur more frequently in African-American and Latino haemophiliacs. Haemophilia 1998;4:68.
    • (1998) Haemophilia , vol.4 , pp. 68
    • Aledort, L.M.1    Dimichele, D.M.2
  • 13
    • 0028266130 scopus 로고
    • A multicenter study of recombinant factor VIII (Recombinate): Safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A
    • Bray GL, Gomperts ED, Courter S, et al. A multicenter study of recombinant factor VIII (Recombinate): safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. Blood 1994;83:2428-2435
    • (1994) Blood , vol.83 , pp. 2428-2435
    • Bray, G.L.1    Gomperts, E.D.2    Courter, S.3
  • 14
    • 0021308824 scopus 로고
    • The natural history of factor VIII inhibitors in patients with hemophilia A
    • Gill FM. The natural history of factor VIII inhibitors in patients with hemophilia A. Prog Clin Biol Res 1984;150:19-29.
    • (1984) Prog Clin Biol Res , vol.150 , pp. 19-29
    • Gill, F.M.1
  • 16
    • 0031773630 scopus 로고    scopus 로고
    • French previously untreated patients with severe hemophilia A after exposure to recombinant factor VIII: Incidence of inhibitor and evaluation of immune tolerance
    • Rothschild C, Laurian Y, Satre EP, et al. French previously untreated patients with severe hemophilia A after exposure to recombinant factor VIII: incidence of inhibitor and evaluation of immune tolerance. Thromb Haemost 1998;80:779-783
    • (1998) Thromb Haemost , vol.80 , pp. 779-783
    • Rothschild, C.1    Laurian, Y.2    Satre, E.P.3
  • 17
    • 34247330151 scopus 로고    scopus 로고
    • A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels
    • Viel KR, Machiah DK, Warren DM, et al. A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels. Blood 2007;109:3713-3724
    • (2007) Blood , vol.109 , pp. 3713-3724
    • Viel, K.R.1    Machiah, D.K.2    Warren, D.M.3
  • 18
    • 65949096345 scopus 로고    scopus 로고
    • African-Americans express multiple haplotypic forms of the wildtype factor VIII (FVIII) protein: A possible role for pharmacogenetics in FVIII inhibitor development?
    • abstract
    • Howard TE, Machiah DK, Tran TT, et al. African-Americans express multiple haplotypic forms of the wildtype factor VIII (FVIII) protein: a possible role for pharmacogenetics in FVIII inhibitor development? Blood 2004;104:113a. abstract.
    • (2004) Blood , vol.104
    • Howard, T.E.1    Machiah, D.K.2    Tran, T.T.3
  • 19
    • 0037325163 scopus 로고    scopus 로고
    • Structure and function of the factor VIII gene and protein
    • Thompson AR. Structure and function of the factor VIII gene and protein. Semin Thromb Hemost 2003;29:11-22. (Pubitemid 36250259)
    • (2003) Seminars in Thrombosis and Hemostasis , vol.29 , Issue.1 , pp. 11-22
    • Thompson, A.R.1
  • 20
    • 0031756660 scopus 로고    scopus 로고
    • Analysis of the F8 gene in individuals with high plasma factor VIII: C levels and associated venous thrombosis
    • Mansvelt EP, Laffan M, McVey JH, Tuddenham EG. Analysis of the F8 gene in individuals with high plasma factor VIII: C levels and associated venous thrombosis. Thromb Haemost 1998;80:561-565
    • (1998) Thromb Haemost , vol.80 , pp. 561-565
    • Mansvelt, E.P.1    Laffan, M.2    McVey, J.H.3    Tuddenham, E.G.4
  • 21
    • 6944221377 scopus 로고    scopus 로고
    • Remembrances of factor VIII. 1. The race to the gene
    • Gitschier J. Remembrances of factor VIII. 1. The race to the gene. J Thromb Haemost 2004;2:383-387
    • (2004) J Thromb Haemost , vol.2 , pp. 383-387
    • Gitschier, J.1
  • 22
    • 0021750055 scopus 로고
    • Characterization of the human factor VIII gene
    • Gitschier J, Wood WI, Goralka TM, et al. Characterization of the human factor VIII gene. Nature 1984;312:326-330
    • (1984) Nature , vol.312 , pp. 326-330
    • Gitschier, J.1    Wood, W.I.2    Goralka, T.M.3
  • 23
    • 0021715169 scopus 로고
    • Molecular cloning of a cDNA encoding human antihaemophilic factor
    • Toole JJ, Knopf JL, Wozney JM, et al. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature 1984;312:342-347
    • (1984) Nature , vol.312 , pp. 342-347
    • Toole, J.J.1    Knopf, J.L.2    Wozney, J.M.3
  • 24
    • 0021677942 scopus 로고
    • Structure of human factor VIII
    • Vehar GA, Keyt B, Eaton D, et al. Structure of human factor VIII. Nature 1984;312:337-342
    • (1984) Nature , vol.312 , pp. 337-342
    • Vehar, G.A.1    Keyt, B.2    Eaton, D.3
  • 25
    • 38349105890 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1 infection correlates strongly with herpes simplex virus-2 (genital herpes) seropositivity in South African and United States blood donations
    • Benjamin RJ, Busch MP, Fang CT, et al. Human immunodeficiency virus-1 infection correlates strongly with herpes simplex virus-2 (genital herpes) seropositivity in South African and United States blood donations. Transfusion 2008;48:295-303.
    • (2008) Transfusion , vol.48 , pp. 295-303
    • Benjamin, R.J.1    Busch, M.P.2    Fang, C.T.3
  • 26
    • 2342611056 scopus 로고    scopus 로고
    • ABO and Rh(D) phenotype frequencies of different racial/ethnic groups in the United States
    • Garratty G, Glynn SA, McEntire R. ABO and Rh(D) phenotype frequencies of different racial/ethnic groups in the United States. Transfusion 2004;44:703-706
    • (2004) Transfusion , vol.44 , pp. 703-706
    • Garratty, G.1    Glynn, S.A.2    McEntire, R.3
  • 27
    • 33744478381 scopus 로고    scopus 로고
    • Factors influencing the decision to donate: Racial and ethnic comparisons
    • Glynn SA, Schreiber GB, Murphy EL, et al. Factors influencing the decision to donate: racial and ethnic comparisons. Transfusion 2006;46:980-990
    • (2006) Transfusion , vol.46 , pp. 980-990
    • Glynn, S.A.1    Schreiber, G.B.2    Murphy, E.L.3
  • 28
    • 3342902745 scopus 로고    scopus 로고
    • Comparison of demographic and donation profiles and transfusion- transmissible disease markers and risk rates in previously transfused and nontransfused blood donors
    • Wang B, Higgins MJ, Kleinman S, et al. Comparison of demographic and donation profiles and transfusion-transmissible disease markers and risk rates in previously transfused and nontransfused blood donors. Transfusion 2004;44:1243-1251
    • (2004) Transfusion , vol.44 , pp. 1243-1251
    • Wang, B.1    Higgins, M.J.2    Kleinman, S.3
  • 29
    • 0031804517 scopus 로고    scopus 로고
    • The factor VIII structure and mutation resource site: HAMSTeRS version 4
    • Kemball-Cook G, Tuddenham EG, Wacey AI. The factor VIII structure and mutation resource site: HAMSTeRS version 4. Nucleic Acids Res 1998;26:216-219
    • (1998) Nucleic Acids Res , vol.26 , pp. 216-219
    • Kemball-Cook, G.1    Tuddenham, E.G.2    Wacey, A.I.3
  • 30
    • 85031359734 scopus 로고    scopus 로고
    • The Pharmacogenetics and Inhibitor Risk (PIR) Study: Establishing the spectrum of factor (F)VIII gene (F8) mutations in African-American hemophilia A patients
    • abstract
    • Howard TE, Machiah DK, Viel KR, et al. The Pharmacogenetics and Inhibitor Risk (PIR) Study: establishing the spectrum of factor (F)VIII gene (F8) mutations in African-American hemophilia A patients. Blood 2005;106:896a. abstract.
    • (2005) Blood , vol.106
    • Howard, T.E.1    Machiah, D.K.2    Viel, K.R.3
  • 31
    • 0016853978 scopus 로고
    • Proceedings: A more uniform measurement of factor VIII inhibitors
    • Kasper CK, Aledort L, Aronson D, et al. Proceedings: a more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh 1975;34:612.
    • (1975) Thromb Diath Haemorrh , vol.34 , pp. 612
    • Kasper, C.K.1    Aledort, L.2    Aronson, D.3
  • 33
    • 0035077234 scopus 로고    scopus 로고
    • Definitions in hemophilia: Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the international society on thrombosis and haemostasis
    • White GC II, Rosendaal F, Aledort LM, Lusher JM, Rothschild C, Ingerslev J. Definitions in hemophilia: recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost 2001;85:560. (Pubitemid 32233035)
    • (2001) Thrombosis and Haemostasis , vol.85 , Issue.3 , pp. 560
    • White II, G.C.1    Rosendaal, F.2    Aledort, L.M.3    Lusher, J.M.4    Rothschild, C.5    Ingerslev, J.6
  • 34
    • 0031955518 scopus 로고    scopus 로고
    • Base-calling of automated sequencer traces using phred. I. Accuracy assessment
    • Ewing B, Hillier L, Wendl MC, Green P. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res 1998;8:175-185
    • (1998) Genome Res , vol.8 , pp. 175-185
    • Ewing, B.1    Hillier, L.2    Wendl, M.C.3    Green, P.4
  • 35
    • 0031978181 scopus 로고    scopus 로고
    • Base-calling of automated sequencer traces using phred. II. Error probabilities
    • Ewing B, Green P. Base-calling of automated sequencer traces using phred. II. Error probabilities. Genome Res 1998;8:186-194
    • (1998) Genome Res , vol.8 , pp. 186-194
    • Ewing, B.1    Green, P.2
  • 36
    • 33646042574 scopus 로고    scopus 로고
    • Int22h-related inversions causing hemophilia A: A novel insight into their origin and a new more discriminant PCR test for their detection
    • Bagnall RD, Giannelli F, Green PM. Int22h-related inversions causing hemophilia A: a novel insight into their origin and a new more discriminant PCR test for their detection. J Thromb Haemost 2006;4:591-598
    • (2006) J Thromb Haemost , vol.4 , pp. 591-598
    • Bagnall, R.D.1    Giannelli, F.2    Green, P.M.3
  • 37
    • 0036096037 scopus 로고    scopus 로고
    • Recurrent inversion breaking intron 1 of the factor VIII gene is a frequent cause of severe hemophilia a
    • DOI 10.1182/blood.V99.1.168
    • Bagnall RD, Waseem N, Green PM, Giannelli F. Recurrent inversion breaking intron 1 of the factor VIII gene is a frequent cause of severe hemophilia A. Blood 2002;99:168-174 (Pubitemid 34532979)
    • (2002) Blood , vol.99 , Issue.1 , pp. 168-174
    • Bagnall, R.D.1    Waseem, N.2    Green, P.M.3    Giannelli, F.4
  • 38
    • 23344454962 scopus 로고    scopus 로고
    • Genotyping the hemophilia inversion hotspot by use of inverse PCR
    • DOI 10.1373/clinchem.2004.046490
    • Rossetti LC, Radic CP, Larripa IB, De Brasi CD. Genotyping the hemophilia inversion hotspot by use of inverse PCR. Clin Chem 2005;51:1154-1158 (Pubitemid 43079392)
    • (2005) Clinical Chemistry , vol.51 , Issue.7 , pp. 1154-1158
    • Rossetti, L.C.1    Radic, C.P.2    Larripa, I.B.3    De Brasi, C.D.4
  • 39
    • 33845239946 scopus 로고    scopus 로고
    • Polymorphisms in the TNFA gene and the risk of inhibitor development in patients with hemophilia A
    • Astermark J, Oldenburg J, Carlson J, et al. Polymorphisms in the TNFA gene and the risk of inhibitor development in patients with hemophilia A. Blood 2006;108:3739-3745
    • (2006) Blood , vol.108 , pp. 3739-3745
    • Astermark, J.1    Oldenburg, J.2    Carlson, J.3
  • 40
    • 33645751563 scopus 로고    scopus 로고
    • Polymorphisms in the IL10 but not in the IL1beta and IL4 genes are associated with inhibitor development in patients with hemophilia A
    • Astermark J, Oldenburg J, Pavlova A, Berntorp E, Lefvert AK. Polymorphisms in the IL10 but not in the IL1beta and IL4 genes are associated with inhibitor development in patients with hemophilia A. Blood 2006;107:3167-3172
    • (2006) Blood , vol.107 , pp. 3167-3172
    • Astermark, J.1    Oldenburg, J.2    Pavlova, A.3    Berntorp, E.4    Lefvert, A.K.5
  • 41
    • 33751014075 scopus 로고    scopus 로고
    • Genetic risk factors for inhibitors to factors VIII and IX
    • Oldenburg J, Pavlova A. Genetic risk factors for inhibitors to factors VIII and IX. Haemophilia 2006;12:Suppl 6:15-22.
    • (2006) Haemophilia , vol.12 , Issue.SUPPL. 6 , pp. 15-22
    • Oldenburg, J.1    Pavlova, A.2
  • 42
    • 24644437294 scopus 로고    scopus 로고
    • Identification of factor VIII gene mutations in 101 patients with haemophilia A: Mutation analysis by inversion screening and multiplex PCR and CSGE and molecular modelling of 10 novel missense substitutions
    • DOI 10.1111/j.1365-2516.2005.01121.x
    • Jayandharan G, Shaji RV, Baidya S, Nair SC, Chandy M, Srivastava A. Identification of factor VIII gene mutations in 101 patients with haemophilia A: mutation analysis by inversion screening and multiplex PCR and CSGE and molecular modelling of 10 novel missense substitutions. Haemophilia 2005;11:481-491 (Pubitemid 41283117)
    • (2005) Haemophilia , vol.11 , Issue.5 , pp. 481-491
    • Jayandharan, G.1    Shaji, R.V.2    Baidya, S.3    Nair, S.C.4    Chandy, M.5    Srivastava, A.6
  • 43
    • 34250727983 scopus 로고    scopus 로고
    • Factor VIII (FVIII) gene mutations in 120 patients with hemophilia A: Detection of 26 novel mutations and correlation with FVIII inhibitor development
    • Repessé Y, Slaoui M, Ferrandiz D, et al. Factor VIII (FVIII) gene mutations in 120 patients with hemophilia A: detection of 26 novel mutations and correlation with FVIII inhibitor development. J Thromb Haemost 2007;5:1469-1476
    • (2007) J Thromb Haemost , vol.5 , pp. 1469-1476
    • Repessé, Y.1    Slaoui, M.2    Ferrandiz, D.3
  • 44
    • 40049086790 scopus 로고    scopus 로고
    • Identification of 217 unreported mutations in the F8 gene in a group of 1,410 unselected Italian patients with hemophilia A
    • Santacroce R, Acquila M, Belvini D, et al. Identification of 217 unreported mutations in the F8 gene in a group of 1,410 unselected Italian patients with hemophilia A. J Hum Genet 2008;53:275-284
    • (2008) J Hum Genet , vol.53 , pp. 275-284
    • Santacroce, R.1    Acquila, M.2    Belvini, D.3
  • 45
    • 47649091913 scopus 로고    scopus 로고
    • The spectrum of the factor 8 (F8) defects in Taiwanese patients with haemophilia A
    • Ma GC, Chang SP, Chen M, Kuo SJ, Chang CS, Shen MC. The spectrum of the factor 8 (F8) defects in Taiwanese patients with haemophilia A. Haemophilia 2008;14:787-795
    • (2008) Haemophilia , vol.14 , pp. 787-795
    • Ma, G.C.1    Chang, S.P.2    Chen, M.3    Kuo, S.J.4    Chang, C.S.5    Shen, M.C.6
  • 46
    • 34248524758 scopus 로고    scopus 로고
    • Spectrum of mutations in Albanian patients with haemophilia A: Identification of ten novel mutations in the factor VIII gene
    • Castaman G, Giacomelli SH, Ghiotto R, et al. Spectrum of mutations in Albanian patients with haemophilia A: identification of ten novel mutations in the factor VIII gene. Haemophilia 2007;13:311-316
    • (2007) Haemophilia , vol.13 , pp. 311-316
    • Castaman, G.1    Giacomelli, S.H.2    Ghiotto, R.3
  • 47
    • 33745749037 scopus 로고    scopus 로고
    • The spectrum of mutations and molecular pathogenesis of hemophilia A in 181 Portuguese patients
    • David D, Ventura C, Moreira I, et al. The spectrum of mutations and molecular pathogenesis of hemophilia A in 181 Portuguese patients. Haematologica 2006;91:840-843
    • (2006) Haematologica , vol.91 , pp. 840-843
    • David, D.1    Ventura, C.2    Moreira, I.3
  • 48
    • 85031364613 scopus 로고    scopus 로고
    • Allelically mismatched replacement therapy due to common African-restricted haplotypes of the factor (F)VIII protein may underlie the increased incidence of FVIII inhibitors observed in hemophilia-A patients of African-descent
    • abstract
    • Howard TE, Viel KR, Fernstrom KM, et al. Allelically mismatched replacement therapy due to common African-restricted haplotypes of the factor (F)VIII protein may underlie the increased incidence of FVIII inhibitors observed in hemophilia-A patients of African-descent. Blood 2006;108:230a. abstract.
    • (2006) Blood , vol.108
    • Howard, T.E.1    Viel, K.R.2    Fernstrom, K.M.3
  • 49
    • 0036626714 scopus 로고    scopus 로고
    • CYP3A4-V and prostate cancer in African Americans: Causal or confounding association because of population stratification?
    • Kittles RA, Chen W, Panguluri RK, et al. CYP3A4-V and prostate cancer in African Americans: causal or confounding association because of population stratification? Hum Genet 2002;110:553-560
    • (2002) Hum Genet , vol.110 , pp. 553-560
    • Kittles, R.A.1    Chen, W.2    Panguluri, R.K.3
  • 50
    • 33746871803 scopus 로고    scopus 로고
    • The effect of assortative mating upon genetic association studies: Spurious associations and population substructure in the absence of admixture
    • DOI 10.1007/s10519-006-9060-0
    • Redden DT, Allison DB. The effect of assortative mating upon genetic association studies: spurious associations and population substructure in the absence of admixture. Behav Genet 2006;36:678-686 (Pubitemid 44188083)
    • (2006) Behavior Genetics , vol.36 , Issue.5 , pp. 678-686
    • Redden, D.T.1    Allison, D.B.2
  • 51
    • 29244467414 scopus 로고    scopus 로고
    • Ad-mixture-matched case-control study: A practical approach for genetic association studies in admixed populations
    • Tsai HJ, Kho JY, Shaikh N, et al. Ad-mixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet 2006;118:626-639
    • (2006) Hum Genet , vol.118 , pp. 626-639
    • Tsai, H.J.1    Kho, J.Y.2    Shaikh, N.3
  • 52
    • 33751017721 scopus 로고    scopus 로고
    • Incidence of inhibitors in a cohort of 838 males with hemophilia A previously treated with factor VIII concentrates
    • Kempton CL, Soucie JM, Abshire TC. Incidence of inhibitors in a cohort of 838 males with hemophilia A previously treated with factor VIII concentrates. J Thromb Haemost 2006;4:2576-2581
    • (2006) J Thromb Haemost , vol.4 , pp. 2576-2581
    • Kempton, C.L.1    Soucie, J.M.2    Abshire, T.C.3
  • 53
    • 33846420672 scopus 로고    scopus 로고
    • Polymorphisms in the CTLA-4 gene and inhibitor development in patients with severe hemophilia a [1]
    • DOI 10.1111/j.1538-7836.2007.02290.x
    • Astermark J, Wang X, Oldenburg J, Berntorp E, Lefvert AK. Polymorphisms in the CTLA-4 gene and inhibitor development in patients with severe hemophilia A. J Thromb Haemost 2007;5:263-265 (Pubitemid 46139449)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.2 , pp. 263-265
    • Astermark, J.1    Wang, X.2    Oldenburg, J.3    Berntorp, E.4    Lefvert, A.-K.5


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