Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network

Journal of Cell Science

Volumn 127, Issue 20, 2014, Pages 4368-4380

  Kanski, Regina ^a   Sneeboer, Marjolein A M ^a   van Bodegraven, Emma J ^a   Sluijs, Jacqueline A ^a   Kropff, Wietske ^a   Vermunt, Marit W ^b   Creyghton, Menno P ^b   de Filippis, Lidia ^c   Vescovi, Angelo ^c,d   Aronica, Eleonora ^e,f,g   van Tijn, Paula ^a,b   van Strien, Miriam E ^a   Hol, Elly M ^a,b,g  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

^f STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

^g UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Alternative splicing; Astrocytes; Epigenetics; GFAP isoforms; Neural stem cells

Indexed keywords

BUTYRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN ALPHA; GLIAL FIBRILLARY ACIDIC PROTEIN DELTA; HISTONE DEACETYLASE 3; NESTIN; PROTEIN; SERINE ARGININE RICH PROTEIN; SYNEMIN; UNCLASSIFIED DRUG; VIMENTIN; HISTONE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; ISOPROTEIN; PROTEIN AGGREGATE; TRICHOSTATIN A;

ALTERNATIVE RNA SPLICING; ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; NERVE CELL NETWORK; PROMOTER REGION; PROTEIN LOCALIZATION; PROTEIN SECONDARY STRUCTURE; TRANSCRIPTION REGULATION; UPREGULATION; ACETYLATION; ALEXANDER DISEASE; CYTOSKELETON; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; METABOLISM; PROTEIN MULTIMERIZATION; TUMOR CELL LINE;

ACETYLATION; ALEXANDER DISEASE; ALTERNATIVE SPLICING; ASTROCYTES; BUTYRIC ACID; CELL LINE, TUMOR; CYTOSKELETON; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HISTONES; HUMANS; HYDROXAMIC ACIDS; PROTEIN AGGREGATES; PROTEIN ISOFORMS; PROTEIN MULTIMERIZATION;

EID: 84918500287     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.145912     Document Type: Article

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