메뉴 건너뛰기




Volumn 34, Issue 5, 2014, Pages 514-519

Role of Sodium Restriction and Diuretic Therapy for "Resistant" Hypertension in Chronic Kidney Disease

Author keywords

Chronic kidney disease; Diuretics; Resistant hypertension; Sodium

Indexed keywords

CHLORTALIDONE; DIURETIC AGENT; FUROSEMIDE; HYDROCHLOROTHIAZIDE; LOOP DIURETIC AGENT; POTASSIUM SPARING DIURETIC AGENT; SPIRONOLACTONE; THIAZIDE DIURETIC AGENT; TRIAMTERENE; ANTIHYPERTENSIVE AGENT; MINERALOCORTICOID ANTAGONIST; SALT INTAKE;

EID: 84918494859     PISSN: 02709295     EISSN: 15584488     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2014.08.005     Document Type: Review
Times cited : (7)

References (56)
  • 1
    • 50549216956 scopus 로고
    • Hypertension explained by Starling's theory of circulatory homoeostasis
    • Borst J.G., Borst-De Geus A. Hypertension explained by Starling's theory of circulatory homoeostasis. Lancet 1963, 1:677-682.
    • (1963) Lancet , vol.1 , pp. 677-682
    • Borst, J.G.1    Borst-De Geus, A.2
  • 3
    • 69549126154 scopus 로고    scopus 로고
    • Sodium restriction improves the gustatory threshold for salty taste in patients with chronic kidney disease
    • Kusaba T., Mori Y., Masami O., Hiroko N., Adachi T., Sugishita C., et al. Sodium restriction improves the gustatory threshold for salty taste in patients with chronic kidney disease. Kidney Int 2009, 76:638-643.
    • (2009) Kidney Int , vol.76 , pp. 638-643
    • Kusaba, T.1    Mori, Y.2    Masami, O.3    Hiroko, N.4    Adachi, T.5    Sugishita, C.6
  • 4
    • 79961214888 scopus 로고    scopus 로고
    • HOlland NEphrology STudy Group. Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial
    • Slagman M.C., Waanders F., Hemmelder M.H., Woittiez A.J., Janssen W.M., Lambers Heerspink H.J., et al. HOlland NEphrology STudy Group. Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial. BMJ 2011, 343:d4366.
    • (2011) BMJ , vol.343 , pp. d4366
    • Slagman, M.C.1    Waanders, F.2    Hemmelder, M.H.3    Woittiez, A.J.4    Janssen, W.M.5    Lambers Heerspink, H.J.6
  • 5
    • 70349249634 scopus 로고    scopus 로고
    • Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial
    • Pimenta E., Gaddam K.K., Oparil S., Aban I., Husain S., Dell'Italia L.J., et al. Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial. Hypertension 2009, 54:475-481.
    • (2009) Hypertension , vol.54 , pp. 475-481
    • Pimenta, E.1    Gaddam, K.K.2    Oparil, S.3    Aban, I.4    Husain, S.5    Dell'Italia, L.J.6
  • 6
    • 0020053596 scopus 로고
    • Salt sensitivity of blood pressure in chronic renal failure. Evidence for renal control of body fluid distribution in man
    • Koomans H.A., Roos J.C., Boer P., Geyskes G.G., Mees E.J. Salt sensitivity of blood pressure in chronic renal failure. Evidence for renal control of body fluid distribution in man. Hypertension 1982, 4:190-197.
    • (1982) Hypertension , vol.4 , pp. 190-197
    • Koomans, H.A.1    Roos, J.C.2    Boer, P.3    Geyskes, G.G.4    Mees, E.J.5
  • 7
    • 0022415128 scopus 로고
    • Natural history of hypertension in renal parenchymal disease
    • Blythe W.B. Natural history of hypertension in renal parenchymal disease. Am J Kidney Dis 1985, 5:A50-A56.
    • (1985) Am J Kidney Dis , vol.5 , pp. A50-A56
    • Blythe, W.B.1
  • 9
    • 1942466547 scopus 로고    scopus 로고
    • Investigators of the TArget Blood Pressure LEvels in Chronic Kidney Disease (TABLE in CKD) Study Group. Achievement of target blood pressure levels in chronic kidney disease: a salty question?
    • De Nicola L., Minutolo R., Bellizzi V., Zoccali C., Cianciaruso B., Andreucci V.E., et al. investigators of the TArget Blood Pressure LEvels in Chronic Kidney Disease (TABLE in CKD) Study Group. Achievement of target blood pressure levels in chronic kidney disease: a salty question?. Am J Kidney Dis 2004, 43:782-795.
    • (2004) Am J Kidney Dis , vol.43 , pp. 782-795
    • De Nicola, L.1    Minutolo, R.2    Bellizzi, V.3    Zoccali, C.4    Cianciaruso, B.5    Andreucci, V.E.6
  • 10
    • 0029054519 scopus 로고
    • Salt-induced increases in systolic blood pressure affect renal hemodynamics and proteinuria
    • Weir M.R., Dengel D.R., Behrens M.T., Goldberg A.P. Salt-induced increases in systolic blood pressure affect renal hemodynamics and proteinuria. Hypertension 1995, 25:1339-1344.
    • (1995) Hypertension , vol.25 , pp. 1339-1344
    • Weir, M.R.1    Dengel, D.R.2    Behrens, M.T.3    Goldberg, A.P.4
  • 11
    • 73349131138 scopus 로고    scopus 로고
    • Benefits of dietary sodium restriction in the management of chronic kidney disease
    • Krikken J.A., Laverman G.D., Navis G. Benefits of dietary sodium restriction in the management of chronic kidney disease. Curr Opin Nephrol Hypertens 2009, 18:531-538.
    • (2009) Curr Opin Nephrol Hypertens , vol.18 , pp. 531-538
    • Krikken, J.A.1    Laverman, G.D.2    Navis, G.3
  • 12
    • 33846502325 scopus 로고    scopus 로고
    • The effect of a shift in sodium intake on renal hemodynamics is determined by body mass index in healthy young men
    • Krikken J.A., Lely A.T., Bakker S.J., Navis G. The effect of a shift in sodium intake on renal hemodynamics is determined by body mass index in healthy young men. Kidney Int 2007, 71:260-265.
    • (2007) Kidney Int , vol.71 , pp. 260-265
    • Krikken, J.A.1    Lely, A.T.2    Bakker, S.J.3    Navis, G.4
  • 13
    • 84879378546 scopus 로고    scopus 로고
    • Salt in health and disease--a delicate balance
    • Kotchen T.A., Cowley A.W., Frohlich E.D. Salt in health and disease--a delicate balance. N Engl J Med 2013, 368:1229-1237.
    • (2013) N Engl J Med , vol.368 , pp. 1229-1237
    • Kotchen, T.A.1    Cowley, A.W.2    Frohlich, E.D.3
  • 14
    • 0029986554 scopus 로고    scopus 로고
    • Salt restriction inhibits renal growth and stabilizes injury in rats with established renal disease
    • Dworkin L.D., Benstein J.A., Tolbert E., Feiner H.D. Salt restriction inhibits renal growth and stabilizes injury in rats with established renal disease. J Am Soc Nephrol 1996, 7:437-442.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 437-442
    • Dworkin, L.D.1    Benstein, J.A.2    Tolbert, E.3    Feiner, H.D.4
  • 15
    • 84875702199 scopus 로고    scopus 로고
    • Dietary sodium restriction prevents kidney damage in high fructose-fed rats
    • Oudot C., Lajoix A.D., Jover B., Rugale C. Dietary sodium restriction prevents kidney damage in high fructose-fed rats. Kidney Int 2013, 83:674-683.
    • (2013) Kidney Int , vol.83 , pp. 674-683
    • Oudot, C.1    Lajoix, A.D.2    Jover, B.3    Rugale, C.4
  • 16
    • 28244466969 scopus 로고    scopus 로고
    • Management of hypertension in chronic kidney disease: the Italian multicentric study
    • De Nicola L., Minutolo R., Gallo C., Zoccali C., Cianciaruso B., Conte M., et al. Management of hypertension in chronic kidney disease: the Italian multicentric study. J Nephrol 2005, 18:397-404.
    • (2005) J Nephrol , vol.18 , pp. 397-404
    • De Nicola, L.1    Minutolo, R.2    Gallo, C.3    Zoccali, C.4    Cianciaruso, B.5    Conte, M.6
  • 18
    • 84869440990 scopus 로고    scopus 로고
    • Resistant hypertension and the neglected antihypertensive: sodium restriction
    • Agarwal R. Resistant hypertension and the neglected antihypertensive: sodium restriction. Nephrol Dial Transplant 2012, 27:4041-4045.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 4041-4045
    • Agarwal, R.1
  • 20
    • 84988584453 scopus 로고    scopus 로고
    • Sodium intake in populations: assessment of evidence
    • May 14
    • Institute of Medicine of the National Academies. Sodium intake in populations: assessment of evidence. May 14, 2013.
    • (2013)
  • 21
    • 84918550144 scopus 로고    scopus 로고
    • Available at: . Accessed september 16
    • K/DOQI Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease. Available at: . Accessed september 16, 2014. http://www.kidney.org/professionals/kdoqi/guidelines_bp/guide_12.htm.
    • (2014)
  • 22
    • 0018364039 scopus 로고
    • Response of deep nephrons and the terminal collecting duct to a reduction in renal mass
    • Buerkert J., Martin D., Prasad J., Chambless S., Klahr S. Response of deep nephrons and the terminal collecting duct to a reduction in renal mass. Am J Physiol 1979, 236:F454-F464.
    • (1979) Am J Physiol , vol.236 , pp. F454-F464
    • Buerkert, J.1    Martin, D.2    Prasad, J.3    Chambless, S.4    Klahr, S.5
  • 23
    • 72049116836 scopus 로고    scopus 로고
    • Use of diuretics in patients with hypertension
    • Ernst M.E., Moser M. Use of diuretics in patients with hypertension. N Engl J Med 2009, 361:2153-2164.
    • (2009) N Engl J Med , vol.361 , pp. 2153-2164
    • Ernst, M.E.1    Moser, M.2
  • 24
    • 79960308450 scopus 로고    scopus 로고
    • Identification of a novel target of thiazide diuretics
    • Eladari D., Chambrey R. Identification of a novel target of thiazide diuretics. J Nephrol 2011, 24:391-394.
    • (2011) J Nephrol , vol.24 , pp. 391-394
    • Eladari, D.1    Chambrey, R.2
  • 25
    • 0032407539 scopus 로고    scopus 로고
    • Thiazide-induced vasodilation in humans is mediated by potassium channel activation
    • Pickkers P., Hughes A.D., Russel F.G., Thien T., Smits P. Thiazide-induced vasodilation in humans is mediated by potassium channel activation. Hypertension 1998, 32:1071-1076.
    • (1998) Hypertension , vol.32 , pp. 1071-1076
    • Pickkers, P.1    Hughes, A.D.2    Russel, F.G.3    Thien, T.4    Smits, P.5
  • 26
    • 77953530398 scopus 로고    scopus 로고
    • Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics
    • Duarte J.D., Cooper-DeHoff R.M. Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther 2010, 8:793-802.
    • (2010) Expert Rev Cardiovasc Ther , vol.8 , pp. 793-802
    • Duarte, J.D.1    Cooper-DeHoff, R.M.2
  • 27
    • 0007215250 scopus 로고
    • Influence of chlorothiazide upon arterial responsiveness to nor-epinephrine in hypertensive subjects
    • Aleksandrow D., Wysznacka W., Gajewski J. Influence of chlorothiazide upon arterial responsiveness to nor-epinephrine in hypertensive subjects. N Engl J Med 1959, 261:1052-1055.
    • (1959) N Engl J Med , vol.261 , pp. 1052-1055
    • Aleksandrow, D.1    Wysznacka, W.2    Gajewski, J.3
  • 28
    • 0011824839 scopus 로고
    • Mechanism of the altered blood pressure responsiveness produced by chlorothiazide
    • Freis E.D., Wanko A., Schnaper H.W., Frohlich E.D. Mechanism of the altered blood pressure responsiveness produced by chlorothiazide. J Clin Invest 1960, 39:1277-1281.
    • (1960) J Clin Invest , vol.39 , pp. 1277-1281
    • Freis, E.D.1    Wanko, A.2    Schnaper, H.W.3    Frohlich, E.D.4
  • 29
    • 13144257671 scopus 로고    scopus 로고
    • Thiazide-like diuretics attenuate agonist-induced vasoconstriction by calcium desensitization linked to Rho kinase
    • Zhu Z., Zhu S., Liu D., Cao T., Wang L., Tepel M. Thiazide-like diuretics attenuate agonist-induced vasoconstriction by calcium desensitization linked to Rho kinase. Hypertension 2005, 45:233-239.
    • (2005) Hypertension , vol.45 , pp. 233-239
    • Zhu, Z.1    Zhu, S.2    Liu, D.3    Cao, T.4    Wang, L.5    Tepel, M.6
  • 30
    • 0034634363 scopus 로고    scopus 로고
    • Mechanisms of methyclothiazide-induced inhibition of contractile responses in rat aorta
    • Colas B., Slama M., Collin T., Safar M., Andrejak M. Mechanisms of methyclothiazide-induced inhibition of contractile responses in rat aorta. Eur J Pharmacol 2000, 408:63-67.
    • (2000) Eur J Pharmacol , vol.408 , pp. 63-67
    • Colas, B.1    Slama, M.2    Collin, T.3    Safar, M.4    Andrejak, M.5
  • 31
    • 0029127275 scopus 로고
    • Diuretic effectiveness of hydrochlorothiazide and furosemide alone and in combination in chronic renal failure
    • Knauf H., Mutschler E. Diuretic effectiveness of hydrochlorothiazide and furosemide alone and in combination in chronic renal failure. J Cardiovasc Pharmacol 1995, 26:394-400.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 394-400
    • Knauf, H.1    Mutschler, E.2
  • 32
    • 84855344370 scopus 로고    scopus 로고
    • A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease
    • Dussol B., Moussi-Frances J., Morange S., Somma-Delpero C., Mundler O., Berland Y. A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease. J Clin Hypertens (Greenwich) 2012, 14:32-37.
    • (2012) J Clin Hypertens (Greenwich) , vol.14 , pp. 32-37
    • Dussol, B.1    Moussi-Frances, J.2    Morange, S.3    Somma-Delpero, C.4    Mundler, O.5    Berland, Y.6
  • 33
    • 84861531899 scopus 로고    scopus 로고
    • Chlorthalidone compared with hydrochlorothiazide in reducing cardiovascular events: systematic review and network meta-analyses
    • Roush G.C., Holford T.R., Guddati A.K. Chlorthalidone compared with hydrochlorothiazide in reducing cardiovascular events: systematic review and network meta-analyses. Hypertension 2012, 59:1110-1117.
    • (2012) Hypertension , vol.59 , pp. 1110-1117
    • Roush, G.C.1    Holford, T.R.2    Guddati, A.K.3
  • 34
    • 84866420019 scopus 로고    scopus 로고
    • Thiazide diuretics in advanced chronic kidney disease
    • Agarwal R., Sinha A.D. Thiazide diuretics in advanced chronic kidney disease. J Am Soc Hypertens 2012, 6:299-308.
    • (2012) J Am Soc Hypertens , vol.6 , pp. 299-308
    • Agarwal, R.1    Sinha, A.D.2
  • 35
    • 0032503682 scopus 로고    scopus 로고
    • Why are physicians not prescribing diuretics more frequently in the management of hypertension?
    • Moser M. Why are physicians not prescribing diuretics more frequently in the management of hypertension?. JAMA 1998, 279:1813-1816.
    • (1998) JAMA , vol.279 , pp. 1813-1816
    • Moser, M.1
  • 36
    • 45149100695 scopus 로고    scopus 로고
    • Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion
    • Gaddam K.K., Nishizaka M.K., Pratt-Ubunama M.N., Pimenta E., Aban I., Oparil S., et al. Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. Arch Intern Med 2008, 168:1159-1164.
    • (2008) Arch Intern Med , vol.168 , pp. 1159-1164
    • Gaddam, K.K.1    Nishizaka, M.K.2    Pratt-Ubunama, M.N.3    Pimenta, E.4    Aban, I.5    Oparil, S.6
  • 37
    • 0028914059 scopus 로고
    • "Escape" of aldosterone production in patients with left ventricular dysfunction treated with an angiotensin converting enzyme inhibitor: implications for therapy
    • Pitt B. "Escape" of aldosterone production in patients with left ventricular dysfunction treated with an angiotensin converting enzyme inhibitor: implications for therapy. Cardiovasc Drugs Ther 1995, 9:145-149.
    • (1995) Cardiovasc Drugs Ther , vol.9 , pp. 145-149
    • Pitt, B.1
  • 38
    • 0033533456 scopus 로고    scopus 로고
    • Comparison of candesartan, enalapril, and their combination in congestive heart failure: randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study Investigators
    • McKelvie R.S., Yusuf S., Pericak D., Avezum A., Burns R.J., Probstfield J., et al. Comparison of candesartan, enalapril, and their combination in congestive heart failure: randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study. The RESOLVD Pilot Study Investigators. Circulation 1999, 100:1056-1064.
    • (1999) Circulation , vol.100 , pp. 1056-1064
    • McKelvie, R.S.1    Yusuf, S.2    Pericak, D.3    Avezum, A.4    Burns, R.J.5    Probstfield, J.6
  • 39
    • 0035369667 scopus 로고    scopus 로고
    • Failure of aldosterone suppression despite angiotensin-converting enzyme (ACE) inhibitor administration in chronic heart failure is associated with ACE DD genotype
    • Cicoira M., Zanolla L., Rossi A., Golia G., Franceschini L., Cabrini G., et al. Failure of aldosterone suppression despite angiotensin-converting enzyme (ACE) inhibitor administration in chronic heart failure is associated with ACE DD genotype. J Am Coll Cardiol 2001, 37:1808-1812.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1808-1812
    • Cicoira, M.1    Zanolla, L.2    Rossi, A.3    Golia, G.4    Franceschini, L.5    Cabrini, G.6
  • 40
    • 73349142401 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blockers and chronic kidney disease
    • Jain G., Campbell R.C., Warnock D.G. Mineralocorticoid receptor blockers and chronic kidney disease. Clin J Am Soc Nephrol 2009, 4:1685-1691.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 1685-1691
    • Jain, G.1    Campbell, R.C.2    Warnock, D.G.3
  • 41
    • 34548163060 scopus 로고    scopus 로고
    • The incidence and implications of aldosterone breakthrough
    • Bomback A.S., Klemmer P.J. The incidence and implications of aldosterone breakthrough. Nat Clin Pract Nephrol 2007, 3:486-492.
    • (2007) Nat Clin Pract Nephrol , vol.3 , pp. 486-492
    • Bomback, A.S.1    Klemmer, P.J.2
  • 42
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B., Zannad F., Remme W.J., Cody R., Castaigne A., Perez A., et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999, 341:709-717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 43
    • 0141617520 scopus 로고    scopus 로고
    • Aldosterone breakthrough during angiotensin-converting enzyme inhibitor therapy
    • Sato A., Saruta T. Aldosterone breakthrough during angiotensin-converting enzyme inhibitor therapy. Am J Hypertens 2003, 16:781-788.
    • (2003) Am J Hypertens , vol.16 , pp. 781-788
    • Sato, A.1    Saruta, T.2
  • 44
    • 34047231332 scopus 로고    scopus 로고
    • Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution?
    • Athyros V.G., Mikhailidis D.P., Kakafika A.I., Tziomalos K., Karagiannis A. Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution?. Expert Opin Pharmacother 2007, 8:529-535.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 529-535
    • Athyros, V.G.1    Mikhailidis, D.P.2    Kakafika, A.I.3    Tziomalos, K.4    Karagiannis, A.5
  • 45
    • 36849005377 scopus 로고    scopus 로고
    • Resistant hypertension and aldosteronism
    • Pimenta E., Calhoun D.A. Resistant hypertension and aldosteronism. Curr Hypertens Rep 2007, 9:353-359.
    • (2007) Curr Hypertens Rep , vol.9 , pp. 353-359
    • Pimenta, E.1    Calhoun, D.A.2
  • 46
    • 0142231538 scopus 로고    scopus 로고
    • Efficacy of low-dose spironolactone in subjects with resistant hypertension
    • Nishizaka M.K., Zaman M.A., Calhoun D.A. Efficacy of low-dose spironolactone in subjects with resistant hypertension. Am J Hypertens 2003, 16:925-930.
    • (2003) Am J Hypertens , vol.16 , pp. 925-930
    • Nishizaka, M.K.1    Zaman, M.A.2    Calhoun, D.A.3
  • 47
    • 79956349197 scopus 로고    scopus 로고
    • Addition of spironolactone in patients with resistant arterial hypertension (ASPIRANT): a randomized, double-blind, placebo-controlled trial
    • Václavík J., Sedlák R., Plachy M., Navrátil K., Plásek J., Jarkovsky J., et al. Addition of spironolactone in patients with resistant arterial hypertension (ASPIRANT): a randomized, double-blind, placebo-controlled trial. Hypertension 2011, 57:1069-1075.
    • (2011) Hypertension , vol.57 , pp. 1069-1075
    • Václavík, J.1    Sedlák, R.2    Plachy, M.3    Navrátil, K.4    Plásek, J.5    Jarkovsky, J.6
  • 48
    • 38149030811 scopus 로고    scopus 로고
    • Change in proteinuria after adding aldosterone blockers to ACE inhibitors or angiotensin receptor blockers in CKD: a systematic review
    • Bomback A.S., Kshirsagar A.V., Amamoo M.A., Klemmer P.J. Change in proteinuria after adding aldosterone blockers to ACE inhibitors or angiotensin receptor blockers in CKD: a systematic review. Am J Kidney Dis 2008, 51:199-211.
    • (2008) Am J Kidney Dis , vol.51 , pp. 199-211
    • Bomback, A.S.1    Kshirsagar, A.V.2    Amamoo, M.A.3    Klemmer, P.J.4
  • 50
    • 33751236177 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus
    • Guo C., Martinez-Vasquez D., Mendez G.P., Toniolo M.F., Yao T.M., Oestreicher E.M., et al. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology 2006, 147:5363-5373.
    • (2006) Endocrinology , vol.147 , pp. 5363-5373
    • Guo, C.1    Martinez-Vasquez, D.2    Mendez, G.P.3    Toniolo, M.F.4    Yao, T.M.5    Oestreicher, E.M.6
  • 51
    • 33646366660 scopus 로고    scopus 로고
    • Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats
    • Han S.Y., Kim C.H., Kim H.S., Jee Y.H., Song H.K., Lee M.H., et al. Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. J Am Soc Nephrol 2006, 17:1362-1372.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1362-1372
    • Han, S.Y.1    Kim, C.H.2    Kim, H.S.3    Jee, Y.H.4    Song, H.K.5    Lee, M.H.6
  • 52
    • 70350710165 scopus 로고    scopus 로고
    • Activation of local aldosterone system within podocytes is involved in apoptosis under diabetic conditions
    • Lee S.H., Yoo T.H., Nam B.Y., Kim D.K., Li J.J., Jung D.S., et al. Activation of local aldosterone system within podocytes is involved in apoptosis under diabetic conditions. Am J Physiol Renal Physiol 2009, 297:F1381-F1390.
    • (2009) Am J Physiol Renal Physiol , vol.297 , pp. F1381-F1390
    • Lee, S.H.1    Yoo, T.H.2    Nam, B.Y.3    Kim, D.K.4    Li, J.J.5    Jung, D.S.6
  • 53
  • 54
    • 4644245230 scopus 로고    scopus 로고
    • Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats
    • Fujisawa G., Okada K., Muto S., Fujita N., Itabashi N., Kusano E., et al. Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats. Kidney Int 2004, 66:1493-1502.
    • (2004) Kidney Int , vol.66 , pp. 1493-1502
    • Fujisawa, G.1    Okada, K.2    Muto, S.3    Fujita, N.4    Itabashi, N.5    Kusano, E.6
  • 55
    • 36349013809 scopus 로고    scopus 로고
    • Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats
    • Yuan J., Jia R., Bao Y. Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats. J Renin Angiotensin Aldosterone Syst 2007, 8:118-126.
    • (2007) J Renin Angiotensin Aldosterone Syst , vol.8 , pp. 118-126
    • Yuan, J.1    Jia, R.2    Bao, Y.3
  • 56
    • 3442888821 scopus 로고    scopus 로고
    • Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system
    • Palmer B.F. Managing hyperkalemia caused by inhibitors of the renin-angiotensin-aldosterone system. N Engl J Med 2004, 351:585-592.
    • (2004) N Engl J Med , vol.351 , pp. 585-592
    • Palmer, B.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.