Salt restriction inhibits renal growth and stabilizes injury in rats with established renal disease

Journal of the American Society of Nephrology

Volumn 7, Issue 3, 1996, Pages 437-442

  Dworkin, Lance D ^a,d   Benstein, Judith A ^b   Tolbert, Evelyn ^a   Feiner, Helen D ^c  

^a BROWN UNIVERSITY   (United States)

^b ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d RHODE ISLAND HOSPITAL   (United States)

Author keywords

Glomerular sclerosis; Hemodynamics; Hypertension; Hypertrophy; Remnant kidney

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GLOMERULOSCLEROSIS; HYPERTENSION; KIDNEY BLOOD FLOW; KIDNEY DEVELOPMENT; KIDNEY DISEASE; KIDNEY HYPERTROPHY; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM RESTRICTION;

EID: 0029986554     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/asn.v73437     Document Type: Article

References (23)

1. Klahr S, Schreiner G, Ichikawa I: The progression of renal disease. N Engl J Med 1988;318:1657-1666.
2. Yoshida Y, Kawamura T, Ikoma M, Fogo A, Ichikawa I: Effects of antihypertensive drugs on glomerular morphology. Kidney Int 1989;36:626-635.
3. Yoshida Y, Fogo A, Ichikawa I: Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis. Kidney Int 1989;35:654-660.
4. Meyer TW, Rennke HG: Progressive glomerular injury following limited infarction in the rat. Am J Physiol 1988;254:F856-F862.
5. Benstein JA, Feiner HD, Parker M, Dworkin LD: Superiority of salt restriction over diuretics in reducing renal hypertrophy and injury in uninephrectomized SHR. Am J Physiol 1990;258:F1675-F1681.
6. Lax DS, Benstein JA, Tolbert E, Dworkin LD: Effects of salt restriction on renal growth and glomerular injury in rats with remnant kidneys. Kidney Int 1992;41:1527-1534.
7. Daniels BS, Hostetter TH: Adverse effects of growth in the glomerular microcirculation. Am J Physiol 1990;258: F1409-F1416.
8. Dworkin LD, Parker M, Tolbert E, Feiner H: Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms. Kidney Int 1993; 43:808-814.
9. Dworkin LD, Hostetter TH, Rennke HG, Brenner BM: Hemodynamic basis for glomerular injury in rats with desoxycorticosterone-salt hypertension. J Clin Invest 1984;73:1448-1461.
10. Kujubu DA, Fine LG: Physiology and cell biology update: Polypeptide growth factors and their relation to renal disease. Am J Kidney Dis 1989;14:61-73.
11. Norman JT, Bohman RE, Fischmann G, et al.: Patterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia. Proc Natl Acad Sci USA 1988;85:6768-6772.
12. Kujubu DA, Norman JT, Herschman HR, Fine LG: Primary response gene expression in renal hypertrophy and hyperplasia: evidence for different growth initiation processes. Am J Physiol 1991;260:F823-F827.
13. Elias H, Hennig A, Schwartz DE: Stereology: Applications to biomedical research. Physiol Rev 1971;51:158-200.
14. Viets JW, Deen WM, Troy JL, Brenner BM: Determination of serum protein concentration in nanoliter blood samples using florescamine or o-phthalaldehyde. Anal Biochem 1978;88:512-521.
15. Baylis C, Deen WM, Meyers BD, Brenner BM: Effects of some vasodilator drugs on transcapillary fluid exchange in renal cortex. Am J Physiol 1976;230:1148-1158.
16. Hostetter TH, Olson JL, Rennke HG, Venkatachalam MA, Brenner BM: Hyperfiltration in remnant nephrons: A potentially adverse response to renal ablation. Am J Physiol 1981;241:F85-F93.
17. Anderson S, Meyer TW, Rennke HG, Brenner BM: Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass. J Clin Invest 1985;76: 612-619.
18. Seyer-Hansen K, Hansen J, Gundersen HJG: Renal hypertrophy in experimental diabetes. Diabetologia 1980;18:501-505.
19. Dworkin LD, Feiner HD, Parker M, Tolbert E: Effects of nifedipine and enalapril on glomerular structure and function in uninephrectomized SHR. Kidney Int 1991; 39:1112-1117.
20. Miskell CA, Simpson DP: Hyperplasia precedes increased glomerular filtration rate in rat remnant kidney. Kidney Int 1990;37:758-766.
21. Nath KA, Kren SM, Hostetter TH: Dietary protein restriction in established renal injury in the rat: selective role of glomerular capillary pressure in progressive glomerular dysfunction. J Clin Invest 1986;78:1199-1205.
22. Meyer TW, Anderson S, Rennke HG, Brenner BM: Reversing glomerular hypertension stabilizes established glomerular injury. Kidney Int 1987;31:751-759.
23. Binet L, Dejours P, Lacaisse A: Action du chlorure de sodium alimentaire sur le developpement ponderal du rein chez le rat. Compt Rend Soc Biol 1950;140:84-87.