Epigenetic silencing of HDAC1 by miR-449a upregulates Runx2 and promotes osteoblast differentiation

International Journal of Molecular Medicine

Volumn 35, Issue 1, 2015, Pages 238-246

  Liu, Te ^a,b   Hou, Lengchen ^a   Zhao, Yanhui ^a   Huang, Yongyi ^c  

^a TONGJI UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c UNIVERSITÉ DE TOULON   (France)

Author keywords

Histone deacetylase 1; Human induced pluripotent stem cells; MicroRNA 449a; Osteoblast differentiation; Runx2

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; COMPLEMENTARY DNA; HISTONE DEACETYLASE 1; HISTONE H3; LUCIFERASE; MESSENGER RNA; MICRORNA; MICRORNA 449A; OSTEOCALCIN; OSTEOPONTIN; RNA; RNA 18S; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR YY1; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; BIOLOGICAL MARKER; HDAC1 PROTEIN, HUMAN; MIRN449 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; AMNION FLUID; ARTICLE; BINDING SITE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CHROMATIN; COCULTURE; CONTROLLED STUDY; EMBRYOID BODY; ENZYME ACTIVITY; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; OSTEOBLAST; PLACENTA; PLURIPOTENT STEM CELL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATORY MECHANISM; REPRESSOR GENE; RNA EXTRACTION; TRANSCRIPTION REGULATION; UPREGULATION; CHEMISTRY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYTOLOGY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PREGNANCY;

3' UNTRANSLATED REGIONS; BASE SEQUENCE; BINDING SITES; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ENDOTHELIAL CELLS; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HISTONE DEACETYLASE 1; HUMANS; MICRORNAS; OSTEOBLASTS; PREGNANCY; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 84917710897     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.2004     Document Type: Article

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