Necrotic core in EMT6/Ro tumour spheroids: Is it caused by an ATP deficit?

Journal of Theoretical Biology

Volumn 262, Issue 1, 2010, Pages 142-150

  Bertuzzi, Alessandro ^a   Fasano, Antonio ^b   Gandolfi, Alberto ^a   Sinisgalli, Carmela ^a  

^a CNR   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Ac CoA; ADP; ATP; Diffusive transport; Energy metabolism; FAD; FADH 2; Free boundary problems; GDP; GTP; NAD +; NADH; Necrosis; P i; Tumour spheroid

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; LACTIC ACID; OXYGEN;

CONCENTRATION (COMPOSITION); GLUCOSE; METABOLISM; METABOLITE; OXYGEN; TUMOR;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL TRANSPORT; DIFFUSION; ENERGY METABOLISM; GLYCOLYSIS; MATHEMATICAL MODEL; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; TUMOR NECROSIS; TUMOR SPHEROID; ANIMAL; CARCINOMA; DOSE RESPONSE; EXPERIMENTAL NEOPLASM; FEMALE; METABOLISM; MULTICELLULAR SPHEROID; NECROSIS; PATHOLOGY; PHYSIOLOGY; THEORETICAL MODEL; TUMOR CELL CULTURE; VALIDATION STUDY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CARCINOMA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FEMALE; GLUCOSE; LACTIC ACID; MAMMARY NEOPLASMS, ANIMAL; MICE; MODELS, THEORETICAL; NECROSIS; OXYGEN; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 76449085182     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2009.09.024     Document Type: Article

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