Oridonin: A small molecule inhibitor of cystic fibrosis transmembrane conductance regulator (CFTR) isolated from traditional Chinese medicine

Fitoterapia

Volumn 100, Issue , 2015, Pages 88-94

  Luan, Jian ^a   Zhang, Yaofang ^a   Yang, Shuang ^a   Wang, Xue ^a   Yu, Bo ^a   Yang, Hong ^a  

^a LIAONING NORMAL UNIVERSITY   (China)

Author keywords

Cholera; Cystic fibrosis transmembrane conductance; High throughput screening (hts); Molecular target; Oridonin; Regulator (cftr); Traditional chinese medicine (tcm)

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ORIDONIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR DELTA F508; HERBACEOUS AGENT; KAURANE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHINESE MEDICINE; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; DRUG ISOLATION; EPITHELIUM CELL; FLUORESCENCE; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; IN VIVO STUDY; INTESTINE; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SHORT CIRCUIT CURRENT; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; HUMAN; ISODON;

MUS; RABDOSIA RUBESCENS; RATTUS;

ANIMALS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DITERPENES, KAURANE; DRUGS, CHINESE HERBAL; EPITHELIAL CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; ISODON; MICE; RATS;

EID: 84916910820     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2014.11.001     Document Type: Article

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