Thymidine phosphorylase activates NFκB and stimulates the expression of angiogenic and metastatic factors in human cancer cells

Oncotarget

Volumn 5, Issue 21, 2014, Pages 10473-10485

  Tabata, Sho ^a   Ikeda, Ryuji ^b   Yamamoto, Masatatsu ^b   Shimaoka, Shunji ^c   Mukaida, Naofumi ^d   Takeda, Yasuo ^b   Yamada, Katsushi ^e   Soga, Tomoyoshi ^a   Furukawa, Tatsuhiko ^b   Akiyama, Shin Ichi ^f  

^a KEIO UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c Nanpuh Hospital   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e NAGASAKI INTERNATIONAL UNIVERSITY   (Japan)

^f NATIONAL KYUSHU CANCER CENTER   (Japan)

Author keywords

IL 8; NF B; ROS; Thymidine phosphorylase

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; REACTIVE OXYGEN METABOLITE; THYMIDINE PHOSPHORYLASE; TRANSCRIPTION FACTOR RELA; FIBRONECTIN; MESSENGER RNA;

ARTICLE; BREAST CARCINOMA; CANCER CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FIBRONECTIN 1 GENE; GENE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IL 6 GENE; IL 8 GENE; METASTASIS; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SQUAMOUS CELL CARCINOMA; STOMACH CANCER; TUMOR VASCULARIZATION; UPREGULATION; UTERINE CERVIX CARCINOMA; APOPTOSIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STOMACH TUMOR; TRANSCRIPTION INITIATION; TUMOR CELL CULTURE; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; THYMIDINE PHOSPHORYLASE; TRANSCRIPTIONAL ACTIVATION; TUMOR CELLS, CULTURED;

EID: 84916882930     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2242     Document Type: Article

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