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Volumn 11, Issue 3, 2015, Pages 1609-1614

Dihydromyricetin induces mouse hepatoma Hepal-6 cell apoptosis via the transforming growth factor-β pathway

Author keywords

Dihydromyricetin; NADPH oxidase 4; Reactive oxygen species; Smad3; Transforming growth factor

Indexed keywords

ANTINEOPLASTIC AGENT; DIHYDROMYRICETIN; FLAVONOID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; FLAVONOL DERIVATIVE; NOX4 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 84916631698     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2891     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 84892428852 scopus 로고    scopus 로고
    • Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma hepg2 cells
    • Wu S, Liu B, Zhang Q, et al: Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma hepg2 cells. PLoS One 8: e76886, 2013.
    • (2013) PLoS One , vol.8 , pp. e76886
    • Wu, S.1    Liu, B.2    Zhang, Q.3
  • 2
    • 58449127516 scopus 로고    scopus 로고
    • Comparison of refluxing, ultrasonic-and microwave-assisted extraction of dihydromyricetin from Ampelopsis grossedentata
    • Li H, Li Y, Zhang Y, Shi H, Hu W and Zhang Z: Comparison of refluxing, ultrasonic-and microwave-assisted extraction of dihydromyricetin from Ampelopsis grossedentata. J AOAC Int 91: 1278-1283, 2008.
    • (2008) J AOAC Int , vol.91 , pp. 1278-1283
    • Li, H.1    Li, Y.2    Zhang, Y.3    Shi, H.4    Hu, W.5    Zhang, Z.6
  • 3
    • 41349109321 scopus 로고    scopus 로고
    • Ampelopsin prevents apoptosis induced by H2O2 in MT-4 lymphocytes
    • Ye J, Guan Y, Zeng S and Liu D: Ampelopsin prevents apoptosis induced by H2O2 in MT-4 lymphocytes. Planta Med 74: 252-257, 2008.
    • (2008) Planta Med , vol.74 , pp. 252-257
    • Ye, J.1    Guan, Y.2    Zeng, S.3    Liu, D.4
  • 5
    • 84895829916 scopus 로고    scopus 로고
    • Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway
    • Zhou Y, Shu F, Liang X, et al: Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway. PLoS One 9: e89021, 2014.
    • (2014) PLoS One , vol.9 , pp. e89021
    • Zhou, Y.1    Shu, F.2    Liang, X.3
  • 6
    • 84863718305 scopus 로고    scopus 로고
    • Ampelopsin inhibits H2O2 -induced apoptosis by ERK and Akt signaling pathways and up-regulation of heme oxygenase-1
    • Kou X, Shen K, An Y, Qi S, Dai WX and Yin Z: Ampelopsin inhibits H2O2 -induced apoptosis by ERK and Akt signaling pathways and up-regulation of heme oxygenase-1. Phytother Res 26: 988-994, 2012.
    • (2012) Phytother Res , vol.26 , pp. 988-994
    • Kou, X.1    Shen, K.2    An, Y.3    Qi, S.4    Dai, W.X.5    Yin, Z.6
  • 7
    • 84856091690 scopus 로고    scopus 로고
    • Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-B signaling pathways
    • Qi S, Xin Y, Guo Y, Diao Y, Kou X, Luo L and Yin Z: Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-B signaling pathways. Int Immunopharmacol 12: 278-287, 2012.
    • (2012) Int Immunopharmacol , vol.12 , pp. 278-287
    • Qi, S.1    Xin, Y.2    Guo, Y.3    Diao, Y.4    Kou, X.5    Luo, L.6    Yin, Z.7
  • 8
    • 51949091268 scopus 로고    scopus 로고
    • Cytotoxic constituents from the bark of Salix hulteni
    • Jeon SH, Chun W, Choi YJ and Kwon YS: Cytotoxic constituents from the bark of Salix hulteni. Arch Pharm Res 31: 978-982, 2008.
    • (2008) Arch Pharm Res , vol.31 , pp. 978-982
    • Jeon, S.H.1    Chun, W.2    Choi, Y.J.3    Kwon, Y.S.4
  • 10
    • 78650974130 scopus 로고    scopus 로고
    • Anti-tumor activity of a novel protein obtained from tartary buckwheat
    • Guo X, Zhu K, Zhang H and Yao H: Anti-tumor activity of a novel protein obtained from tartary buckwheat. Int J Mol Sci 11: 5201-5211, 2010.
    • (2010) Int J Mol Sci , vol.11 , pp. 5201-5211
    • Guo, X.1    Zhu, K.2    Zhang, H.3    Yao, H.4
  • 11
    • 84905851531 scopus 로고    scopus 로고
    • Dihydromyricetin inhibits migration and invasion of hepatoma cells through regulation of MMP-9 expression
    • Zhang QY, Li R, Zeng GF, et al: Dihydromyricetin inhibits migration and invasion of hepatoma cells through regulation of MMP-9 expression. World J Gastroenterol 20: 10082-10093, 2014.
    • (2014) World J Gastroenterol , vol.20 , pp. 10082-10093
    • Zhang, Q.Y.1    Li, R.2    Zeng, G.F.3
  • 13
    • 84878588513 scopus 로고    scopus 로고
    • Insights into the transforming growth factor signaling pathway in cutaneous melanoma
    • Perrot CY, Javelaud D and Mauviel A: Insights into the transforming growth factor signaling pathway in cutaneous melanoma. Ann Dermatol 25: 135-144, 2013.
    • (2013) Ann Dermatol , vol.25 , pp. 135-144
    • Perrot, C.Y.1    Javelaud, D.2    Mauviel, A.3
  • 14
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-beta signal transduction
    • Moustakas A, Souchelnytskyi S and Heldin CH: Smad regulation in TGF-beta signal transduction. J Cell Sci 114 (Pt 24): 4359-4369, 2001.
    • (2001) J Cell Sci , vol.114 , pp. 4359-4369
    • Moustakas, A.1    Souchelnytskyi, S.2    Heldin, C.H.3
  • 15
    • 78649969033 scopus 로고    scopus 로고
    • The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF?-SMAD pathway
    • Varelas X, Samavarchi-Tehrani P, Narimatsu M, et al: The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF?-SMAD pathway. Developmental cell 19: 831-844, 2010.
    • (2010) Developmental Cell , vol.19 , pp. 831-844
    • Varelas, X.1    Samavarchi-Tehrani, P.2    Narimatsu, M.3
  • 17
    • 77957234116 scopus 로고    scopus 로고
    • NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration
    • Tobar N, Guerrero J, Smith PC and Martínez J: NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration. Br J Cancer 103: 1040-1047, 2010.
    • (2010) Br J Cancer , vol.103 , pp. 1040-1047
    • Tobar, N.1    Guerrero, J.2    Smith, P.C.3    Martínez, J.4
  • 18
    • 72849147487 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor -dependent manner: A new contributor to HCV-induced oxidative stress
    • Boudreau HE, Emerson SU, Korzeniowska A, Jendrysik MA and Leto TL: Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor -dependent manner: a new contributor to HCV-induced oxidative stress. J Virol 83: 12934-12946, 2009.
    • (2009) J Virol , vol.83 , pp. 12934-12946
    • Boudreau, H.E.1    Emerson, S.U.2    Korzeniowska, A.3    Jendrysik, M.A.4    Leto, T.L.5
  • 19
    • 79954570719 scopus 로고    scopus 로고
    • Myofibroblast differentiation during fibrosis: Role of NAD(P)H oxidases
    • Barnes JL and Gorin Y: Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int 79: 944-956, 2011.
    • (2011) Kidney Int , vol.79 , pp. 944-956
    • Barnes, J.L.1    Gorin, Y.2
  • 20
    • 74149085153 scopus 로고    scopus 로고
    • Oxidative stress and glutathione in TGF?-mediated fibrogenesis
    • Liu R-M and Gaston Pravia K: Oxidative stress and glutathione in TGF?-mediated fibrogenesis. Free Radical Biology and Medicine 48: 1-15, 2010.
    • (2010) Free Radical Biology and Medicine , vol.48 , pp. 1-15
    • Liu, R.-M.1    Gaston Pravia, K.2
  • 21
    • 79955601028 scopus 로고    scopus 로고
    • Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
    • Pike LS, Smift AL, Croteau NJ, Ferrick DA and Wu M: Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells. Biochim Biophys Acta 1807: 726-734, 2011.
    • (2011) Biochim Biophys Acta , vol.1807 , pp. 726-734
    • Pike, L.S.1    Smift, A.L.2    Croteau, N.J.3    Ferrick, D.A.4    Wu, M.5
  • 25
    • 77954759030 scopus 로고    scopus 로고
    • The human Mediator complex: A versatile, genome-wide regulator of transcription
    • Taatjes DJ: The human Mediator complex: a versatile, genome-wide regulator of transcription. Trends Biochem Sci 35: 315-322, 2010.
    • (2010) Trends Biochem Sci , vol.35 , pp. 315-322
    • Taatjes, D.J.1
  • 27
    • 79960838436 scopus 로고    scopus 로고
    • The TGF/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system
    • Wiercinska E, Naber HP, Pardali E, van der Pluijm G, van Dam H and ten Dijke P: The TGF/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system. Breast Cancer Res Treat 128: 657-666, 2011.
    • (2011) Breast Cancer Res Treat , vol.128 , pp. 657-666
    • Wiercinska, E.1    Naber, H.P.2    Pardali, E.3    Van Der Pluijm, G.4    Van Dam, H.5    Ten Dijke, P.6
  • 30
    • 0026021362 scopus 로고
    • Production of large amounts of hydrogen peroxide by human tumor cells
    • Szatrowski TP and Nathan CF: Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 51: 794-798, 1991.
    • (1991) Cancer Res , vol.51 , pp. 794-798
    • Szatrowski, T.P.1    Nathan, C.F.2
  • 31
    • 70350231912 scopus 로고    scopus 로고
    • Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis
    • Bierie B and Moses HL: Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis. Cell Cycle 8: 3319-3327, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 3319-3327
    • Bierie, B.1    Moses, H.L.2
  • 35
    • 77953809992 scopus 로고    scopus 로고
    • Redox-optimized ROS balance: A unifying hypothesis
    • Aon MA, Cortassa S and O'Rourke B: Redox-optimized ROS balance: a unifying hypothesis. Biochim Biophys Acta 1797: 865-877, 2010.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 865-877
    • Aon, M.A.1    Cortassa, S.2    O'Rourke, B.3
  • 36
    • 78649700266 scopus 로고    scopus 로고
    • Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors
    • Parga J, Rodríguez-Pallares J, Joglar B, Diaz-Ruiz C, Guerra M and Labandeira-Garcia JL: Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors. Dev Dyn 239: 3247-3259, 2010.
    • (2010) Dev Dyn , vol.239 , pp. 3247-3259
    • Parga, J.1    Rodríguez-Pallares, J.2    Joglar, B.3    Diaz-Ruiz, C.4    Guerra, M.5    Labandeira-Garcia, J.L.6
  • 37
    • 49749100079 scopus 로고    scopus 로고
    • NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts
    • Li S, Tabar SS, Malec V, Eul BG, Klepetko W, Weissmann N, Grimminger F, Seeger W, Rose F, and Hänze J: NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts. Antioxid Redox Signal 10: 1687-1698, 2008.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1687-1698
    • Li, S.1    Tabar, S.S.2    Malec, V.3    Eul, B.G.4    Klepetko, W.5    Weissmann, N.6    Grimminger, F.7    Seeger, W.8    Rose, F.9    Hänze, J.10
  • 38
    • 77952407681 scopus 로고    scopus 로고
    • Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts
    • Liu RM, Choi J, Wu JH, Gaston Pravia KA, Lewis KM, Brand JD, Mochel NS, Krzywanski DM, Lambeth JD, Hagood JS, et al: Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts. J Biol Chem 285: 16239-16247, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 16239-16247
    • Liu, R.M.1    Choi, J.2    Wu, J.H.3    Gaston Pravia, K.A.4    Lewis, K.M.5    Brand, J.D.6    Mochel, N.S.7    Krzywanski, D.M.8    Lambeth, J.D.9    Hagood, J.S.10
  • 39
    • 74149085153 scopus 로고    scopus 로고
    • Oxidative stress and glutathione in TGF?-mediated fibrogenesis
    • Liu R-M and Gaston Pravia K: Oxidative stress and glutathione in TGF?-mediated fibrogenesis. Free Radic Biol Med 48: 1-15, 2010.
    • (2010) Free Radic Biol Med , vol.48 , pp. 1-15
    • Liu, R.-M.1    Gaston Pravia, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.