-
1
-
-
84892428852
-
Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma hepg2 cells
-
Wu S, Liu B, Zhang Q, et al: Dihydromyricetin reduced Bcl-2 expression via p53 in human hepatoma hepg2 cells. PLoS One 8: e76886, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e76886
-
-
Wu, S.1
Liu, B.2
Zhang, Q.3
-
2
-
-
58449127516
-
Comparison of refluxing, ultrasonic-and microwave-assisted extraction of dihydromyricetin from Ampelopsis grossedentata
-
Li H, Li Y, Zhang Y, Shi H, Hu W and Zhang Z: Comparison of refluxing, ultrasonic-and microwave-assisted extraction of dihydromyricetin from Ampelopsis grossedentata. J AOAC Int 91: 1278-1283, 2008.
-
(2008)
J AOAC Int
, vol.91
, pp. 1278-1283
-
-
Li, H.1
Li, Y.2
Zhang, Y.3
Shi, H.4
Hu, W.5
Zhang, Z.6
-
3
-
-
41349109321
-
Ampelopsin prevents apoptosis induced by H2O2 in MT-4 lymphocytes
-
Ye J, Guan Y, Zeng S and Liu D: Ampelopsin prevents apoptosis induced by H2O2 in MT-4 lymphocytes. Planta Med 74: 252-257, 2008.
-
(2008)
Planta Med
, vol.74
, pp. 252-257
-
-
Ye, J.1
Guan, Y.2
Zeng, S.3
Liu, D.4
-
4
-
-
57749096180
-
Cytotoxic, antioxidant, and antimicrobial activities of Ampelopsis brevipedunculata and Parthenocissus tricuspidata (Vitaceae)
-
Kundaković K, Stanojković T, Milenković M, Grubin J, Juranić Z, Stevanović B and Kova-ević N: Cytotoxic, antioxidant, and antimicrobial activities of Ampelopsis brevipedunculata and Parthenocissus tricuspidata (Vitaceae). Arch Biol Sci 60: 641-647, 2008.
-
(2008)
Arch Biol Sci
, vol.60
, pp. 641-647
-
-
Kundaković, K.1
Stanojković, T.2
Milenković, M.3
Grubin, J.4
Juranić, Z.5
Stevanović, B.6
Kova-Ević, N.7
-
5
-
-
84895829916
-
Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway
-
Zhou Y, Shu F, Liang X, et al: Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway. PLoS One 9: e89021, 2014.
-
(2014)
PLoS One
, vol.9
, pp. e89021
-
-
Zhou, Y.1
Shu, F.2
Liang, X.3
-
6
-
-
84863718305
-
Ampelopsin inhibits H2O2 -induced apoptosis by ERK and Akt signaling pathways and up-regulation of heme oxygenase-1
-
Kou X, Shen K, An Y, Qi S, Dai WX and Yin Z: Ampelopsin inhibits H2O2 -induced apoptosis by ERK and Akt signaling pathways and up-regulation of heme oxygenase-1. Phytother Res 26: 988-994, 2012.
-
(2012)
Phytother Res
, vol.26
, pp. 988-994
-
-
Kou, X.1
Shen, K.2
An, Y.3
Qi, S.4
Dai, W.X.5
Yin, Z.6
-
7
-
-
84856091690
-
Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-B signaling pathways
-
Qi S, Xin Y, Guo Y, Diao Y, Kou X, Luo L and Yin Z: Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-B signaling pathways. Int Immunopharmacol 12: 278-287, 2012.
-
(2012)
Int Immunopharmacol
, vol.12
, pp. 278-287
-
-
Qi, S.1
Xin, Y.2
Guo, Y.3
Diao, Y.4
Kou, X.5
Luo, L.6
Yin, Z.7
-
8
-
-
51949091268
-
Cytotoxic constituents from the bark of Salix hulteni
-
Jeon SH, Chun W, Choi YJ and Kwon YS: Cytotoxic constituents from the bark of Salix hulteni. Arch Pharm Res 31: 978-982, 2008.
-
(2008)
Arch Pharm Res
, vol.31
, pp. 978-982
-
-
Jeon, S.H.1
Chun, W.2
Choi, Y.J.3
Kwon, Y.S.4
-
10
-
-
78650974130
-
Anti-tumor activity of a novel protein obtained from tartary buckwheat
-
Guo X, Zhu K, Zhang H and Yao H: Anti-tumor activity of a novel protein obtained from tartary buckwheat. Int J Mol Sci 11: 5201-5211, 2010.
-
(2010)
Int J Mol Sci
, vol.11
, pp. 5201-5211
-
-
Guo, X.1
Zhu, K.2
Zhang, H.3
Yao, H.4
-
11
-
-
84905851531
-
Dihydromyricetin inhibits migration and invasion of hepatoma cells through regulation of MMP-9 expression
-
Zhang QY, Li R, Zeng GF, et al: Dihydromyricetin inhibits migration and invasion of hepatoma cells through regulation of MMP-9 expression. World J Gastroenterol 20: 10082-10093, 2014.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 10082-10093
-
-
Zhang, Q.Y.1
Li, R.2
Zeng, G.F.3
-
13
-
-
84878588513
-
Insights into the transforming growth factor signaling pathway in cutaneous melanoma
-
Perrot CY, Javelaud D and Mauviel A: Insights into the transforming growth factor signaling pathway in cutaneous melanoma. Ann Dermatol 25: 135-144, 2013.
-
(2013)
Ann Dermatol
, vol.25
, pp. 135-144
-
-
Perrot, C.Y.1
Javelaud, D.2
Mauviel, A.3
-
14
-
-
0035694910
-
Smad regulation in TGF-beta signal transduction
-
Moustakas A, Souchelnytskyi S and Heldin CH: Smad regulation in TGF-beta signal transduction. J Cell Sci 114 (Pt 24): 4359-4369, 2001.
-
(2001)
J Cell Sci
, vol.114
, pp. 4359-4369
-
-
Moustakas, A.1
Souchelnytskyi, S.2
Heldin, C.H.3
-
15
-
-
78649969033
-
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF?-SMAD pathway
-
Varelas X, Samavarchi-Tehrani P, Narimatsu M, et al: The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF?-SMAD pathway. Developmental cell 19: 831-844, 2010.
-
(2010)
Developmental Cell
, vol.19
, pp. 831-844
-
-
Varelas, X.1
Samavarchi-Tehrani, P.2
Narimatsu, M.3
-
17
-
-
77957234116
-
NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration
-
Tobar N, Guerrero J, Smith PC and Martínez J: NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration. Br J Cancer 103: 1040-1047, 2010.
-
(2010)
Br J Cancer
, vol.103
, pp. 1040-1047
-
-
Tobar, N.1
Guerrero, J.2
Smith, P.C.3
Martínez, J.4
-
18
-
-
72849147487
-
Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor -dependent manner: A new contributor to HCV-induced oxidative stress
-
Boudreau HE, Emerson SU, Korzeniowska A, Jendrysik MA and Leto TL: Hepatitis C virus (HCV) proteins induce NADPH oxidase 4 expression in a transforming growth factor -dependent manner: a new contributor to HCV-induced oxidative stress. J Virol 83: 12934-12946, 2009.
-
(2009)
J Virol
, vol.83
, pp. 12934-12946
-
-
Boudreau, H.E.1
Emerson, S.U.2
Korzeniowska, A.3
Jendrysik, M.A.4
Leto, T.L.5
-
19
-
-
79954570719
-
Myofibroblast differentiation during fibrosis: Role of NAD(P)H oxidases
-
Barnes JL and Gorin Y: Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int 79: 944-956, 2011.
-
(2011)
Kidney Int
, vol.79
, pp. 944-956
-
-
Barnes, J.L.1
Gorin, Y.2
-
21
-
-
79955601028
-
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
-
Pike LS, Smift AL, Croteau NJ, Ferrick DA and Wu M: Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells. Biochim Biophys Acta 1807: 726-734, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1807
, pp. 726-734
-
-
Pike, L.S.1
Smift, A.L.2
Croteau, N.J.3
Ferrick, D.A.4
Wu, M.5
-
23
-
-
78650255998
-
The role of the TGF coreceptor endoglin in cancer
-
Pérez-Gómez E, Del Castillo G, Santibáñez JF, Lopez-Novoa JM, Bernabéu C and Quintanilla M: The role of the TGF coreceptor endoglin in cancer. Scientific World Journal 10: 2367-2384, 2010.
-
(2010)
Scientific World Journal
, vol.10
, pp. 2367-2384
-
-
Pérez-Gómez, E.1
Del Castillo, G.2
Santibáñez, J.F.3
Lopez-Novoa, J.M.4
Bernabéu, C.5
Quintanilla, M.6
-
24
-
-
79955083102
-
Transforming growth factor adaptor, -2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer
-
Baek HJ, Pishvaian MJ, Tang Y, Kim TH, Yang S, Zouhairi ME, Mendelson J, Shetty K, Kallakury B, Berry DL, et al: Transforming growth factor adaptor, -2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer. Hepatology 53: 1676-1684, 2011.
-
(2011)
Hepatology
, vol.53
, pp. 1676-1684
-
-
Baek, H.J.1
Pishvaian, M.J.2
Tang, Y.3
Kim, T.H.4
Yang, S.5
Zouhairi, M.E.6
Mendelson, J.7
Shetty, K.8
Kallakury, B.9
Berry, D.L.10
-
25
-
-
77954759030
-
The human Mediator complex: A versatile, genome-wide regulator of transcription
-
Taatjes DJ: The human Mediator complex: a versatile, genome-wide regulator of transcription. Trends Biochem Sci 35: 315-322, 2010.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 315-322
-
-
Taatjes, D.J.1
-
27
-
-
79960838436
-
The TGF/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system
-
Wiercinska E, Naber HP, Pardali E, van der Pluijm G, van Dam H and ten Dijke P: The TGF/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system. Breast Cancer Res Treat 128: 657-666, 2011.
-
(2011)
Breast Cancer Res Treat
, vol.128
, pp. 657-666
-
-
Wiercinska, E.1
Naber, H.P.2
Pardali, E.3
Van Der Pluijm, G.4
Van Dam, H.5
Ten Dijke, P.6
-
28
-
-
77949265948
-
Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis
-
Petersen M, Pardali E, Van Der Horst G, Cheung H, van den Hoogen C, van der Pluijm G and Ten Dijke P: Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis. Oncogene 29: 1351-1361, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 1351-1361
-
-
Petersen, M.1
Pardali, E.2
Van Der Horst, G.3
Cheung, H.4
Van Den Hoogen, C.5
Van Der Pluijm, G.6
Ten Dijke, P.7
-
29
-
-
69449088675
-
Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells
-
Dzwonek J, Preobrazhenska O, Cazzola S, Conidi A, Schellens A, van Dinther M, Stubbs A, Klippel A, Huylebroeck D, ten Dijke P and Verschueren K: Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells. Mol Cancer Res 7: 1342-1353, 2009.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1342-1353
-
-
Dzwonek, J.1
Preobrazhenska, O.2
Cazzola, S.3
Conidi, A.4
Schellens, A.5
Van Dinther, M.6
Stubbs, A.7
Klippel, A.8
Huylebroeck, D.9
Ten Dijke, P.10
Verschueren, K.11
-
30
-
-
0026021362
-
Production of large amounts of hydrogen peroxide by human tumor cells
-
Szatrowski TP and Nathan CF: Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 51: 794-798, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 794-798
-
-
Szatrowski, T.P.1
Nathan, C.F.2
-
31
-
-
70350231912
-
Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis
-
Bierie B and Moses HL: Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis. Cell Cycle 8: 3319-3327, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 3319-3327
-
-
Bierie, B.1
Moses, H.L.2
-
32
-
-
67651005826
-
Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer
-
Bierie B, Chung CH, Parker JS, Stover DG, Cheng N, Chytil A, Aakre M, Shyr Y and Moses HL: Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer. J Clin Invest 119: 1571-1582, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 1571-1582
-
-
Bierie, B.1
Chung, C.H.2
Parker, J.S.3
Stover, D.G.4
Cheng, N.5
Chytil, A.6
Aakre, M.7
Shyr, Y.8
Moses, H.L.9
-
33
-
-
37349100945
-
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis
-
Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, Carbone DP, Matrisian LM, Richmond A, Lin PC and Moses HL: Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell 13: 23-35, 2008.
-
(2008)
Cancer Cell
, vol.13
, pp. 23-35
-
-
Yang, L.1
Huang, J.2
Ren, X.3
Gorska, A.E.4
Chytil, A.5
Aakre, M.6
Carbone, D.P.7
Matrisian, L.M.8
Richmond, A.9
Lin, P.C.10
Moses, H.L.11
-
34
-
-
79251633236
-
Inhibiting TGF signaling in hepatocellular carcinoma
-
Giannelli G, Mazzocca A, Fransvea E, Lahn M and Antonaci S: Inhibiting TGF signaling in hepatocellular carcinoma. Biochim Biophys Acta 1815: 214-223, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1815
, pp. 214-223
-
-
Giannelli, G.1
Mazzocca, A.2
Fransvea, E.3
Lahn, M.4
Antonaci, S.5
-
35
-
-
77953809992
-
Redox-optimized ROS balance: A unifying hypothesis
-
Aon MA, Cortassa S and O'Rourke B: Redox-optimized ROS balance: a unifying hypothesis. Biochim Biophys Acta 1797: 865-877, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 865-877
-
-
Aon, M.A.1
Cortassa, S.2
O'Rourke, B.3
-
36
-
-
78649700266
-
Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors
-
Parga J, Rodríguez-Pallares J, Joglar B, Diaz-Ruiz C, Guerra M and Labandeira-Garcia JL: Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors. Dev Dyn 239: 3247-3259, 2010.
-
(2010)
Dev Dyn
, vol.239
, pp. 3247-3259
-
-
Parga, J.1
Rodríguez-Pallares, J.2
Joglar, B.3
Diaz-Ruiz, C.4
Guerra, M.5
Labandeira-Garcia, J.L.6
-
37
-
-
49749100079
-
NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts
-
Li S, Tabar SS, Malec V, Eul BG, Klepetko W, Weissmann N, Grimminger F, Seeger W, Rose F, and Hänze J: NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts. Antioxid Redox Signal 10: 1687-1698, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 1687-1698
-
-
Li, S.1
Tabar, S.S.2
Malec, V.3
Eul, B.G.4
Klepetko, W.5
Weissmann, N.6
Grimminger, F.7
Seeger, W.8
Rose, F.9
Hänze, J.10
-
38
-
-
77952407681
-
Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts
-
Liu RM, Choi J, Wu JH, Gaston Pravia KA, Lewis KM, Brand JD, Mochel NS, Krzywanski DM, Lambeth JD, Hagood JS, et al: Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts. J Biol Chem 285: 16239-16247, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 16239-16247
-
-
Liu, R.M.1
Choi, J.2
Wu, J.H.3
Gaston Pravia, K.A.4
Lewis, K.M.5
Brand, J.D.6
Mochel, N.S.7
Krzywanski, D.M.8
Lambeth, J.D.9
Hagood, J.S.10
-
39
-
-
74149085153
-
Oxidative stress and glutathione in TGF?-mediated fibrogenesis
-
Liu R-M and Gaston Pravia K: Oxidative stress and glutathione in TGF?-mediated fibrogenesis. Free Radic Biol Med 48: 1-15, 2010.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 1-15
-
-
Liu, R.-M.1
Gaston Pravia, K.2
-
40
-
-
69949114515
-
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
-
Hecker L, Vittal R, Jones T, Jagirdar R, Luckhardt TR, Horowitz JC, Pennathur S, Martinez FJ and Thannickal VJ: NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nat Med 15: 1077-1081, 2009.
-
(2009)
Nat Med
, vol.15
, pp. 1077-1081
-
-
Hecker, L.1
Vittal, R.2
Jones, T.3
Jagirdar, R.4
Luckhardt, T.R.5
Horowitz, J.C.6
Pennathur, S.7
Martinez, F.J.8
Thannickal, V.J.9
|