-
1
-
-
84880982342
-
Radiation-induced epigenetic DNA methylation modification of radiation-response pathways
-
Antwih DA, Gabbara KM, Lancaster WD, Ruden DM, Zielske SP. 2013. Radiation-induced epigenetic DNA methylation modification of radiation-response pathways. Epigenetics 8:839-848.
-
(2013)
Epigenetics
, vol.8
, pp. 839-848
-
-
Antwih, D.A.1
Gabbara, K.M.2
Lancaster, W.D.3
Ruden, D.M.4
Zielske, S.P.5
-
2
-
-
84893061501
-
Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1
-
Asgatay S, Champion C, Marloie G, Drujon T, Senamaud-Beaufort C, Ceccaldi A, Erdmann A, Rajavelu A, Schambel P, Jeltsch A, Lequin O, Karoyan P, Arimondo PB, Guianvarc'h D. 2014. Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1. J Med Chem 57:421-434.
-
(2014)
J Med Chem
, vol.57
, pp. 421-434
-
-
Asgatay, S.1
Champion, C.2
Marloie, G.3
Drujon, T.4
Senamaud-Beaufort, C.5
Ceccaldi, A.6
Erdmann, A.7
Rajavelu, A.8
Schambel, P.9
Jeltsch, A.10
Lequin, O.11
Karoyan, P.12
Arimondo, P.B.13
Guianvarc'H, D.14
-
3
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
Bibikova M, Barnes B, Tsan C, Ho V, Klotzle B, Le JM Delano, Zhang L, Schroth GP, Gunderson KL, Fan JB, Shen R. 2011. High density DNA methylation array with single CpG site resolution. Genomics 98:288-295.
-
(2011)
Genomics
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
Ho, V.4
Klotzle, B.5
Le, J.M.D.6
Zhang, L.7
Schroth, G.P.8
Gunderson, K.L.9
Fan, J.B.10
Shen, R.11
-
4
-
-
84856135052
-
Pharmacological genome demethylation increases radiosensitivity of head and neck squamous carcinoma cells
-
Brieger J, Mann SA, Pongsapich W, Koutsimpelas D, Fruth K, Mann WJ. 2012. Pharmacological genome demethylation increases radiosensitivity of head and neck squamous carcinoma cells. Int J Mol Med 29:505-509.
-
(2012)
Int J Mol Med
, vol.29
, pp. 505-509
-
-
Brieger, J.1
Mann, S.A.2
Pongsapich, W.3
Koutsimpelas, D.4
Fruth, K.5
Mann, W.J.6
-
5
-
-
84895902929
-
Zebularine significantly sensitises MEC1 cells to external irradiation and radio-pharmaceutical therapy when administered sequentially in vitro
-
Bryan JN, Kumar SR, Jia F, Balkin ER, Lewis MR. 2014. Zebularine significantly sensitises MEC1 cells to external irradiation and radio-pharmaceutical therapy when administered sequentially in vitro. Cell Biol Int 38:187-197.
-
(2014)
Cell Biol Int
, vol.38
, pp. 187-197
-
-
Bryan, J.N.1
Kumar, S.R.2
Jia, F.3
Balkin, E.R.4
Lewis, M.R.5
-
6
-
-
84866940776
-
The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases
-
Chen CC, Wang KY, Shen CK. 2012. The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases. J Biol Chem 287:33116-33121.
-
(2012)
J Biol Chem
, vol.287
, pp. 33116-33121
-
-
Chen, C.C.1
Wang, K.Y.2
Shen, C.K.3
-
7
-
-
84875990730
-
DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases
-
Chen CC, Wang KY, Shen CK. 2013. DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases. J Biol Chem 288:9084-9091.
-
(2013)
J Biol Chem
, vol.288
, pp. 9084-9091
-
-
Chen, C.C.1
Wang, K.Y.2
Shen, C.K.3
-
8
-
-
59649094562
-
A systematic assessment of radiation dose enhancement by 5-Aza-2′-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma
-
De Schutter H, Kimpe M, Isebaert S, Nuyts S. 2009.A systematic assessment of radiation dose enhancement by 5-Aza-2′-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys 73:904-912.
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.73
, pp. 904-912
-
-
De Schutter, H.1
Kimpe, M.2
Isebaert, S.3
Nuyts, S.4
-
9
-
-
20444478652
-
Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine
-
Dote H, Cerna D, Burgan WE, Carter DJ, Cerra MA, Hollingshead MG, Camphausen K, Tofilon PJ. 2005. Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine. Clin Cancer Res 11:4571-4579.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4571-4579
-
-
Dote, H.1
Cerna, D.2
Burgan, W.E.3
Carter, D.J.4
Cerra, M.A.5
Hollingshead, M.G.6
Camphausen, K.7
Tofilon, P.J.8
-
10
-
-
84906262675
-
Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
-
Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes, Nebdal GI, Syljuasen D, Touleimat RG, Busato N, Tost F, Saetersdal J, Borresen-Dale AB, Kristensen AL, Edvardsen V. 2014. Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy. Int J Cancer 135:2085-2095.
-
(2014)
Int J Cancer
, vol.135
, pp. 2085-2095
-
-
Halvorsen, A.R.1
Helland, A.2
Fleischer, T.3
Haug, K.M.4
Alnaes, G.5
Nebdal, G.I.6
Syljuasen, D.7
Touleimat, R.G.8
Busato, N.9
Tost, F.10
Saetersdal, J.11
Borresen-Dale, A.B.12
Kristensen, A.L.13
Edvardsen, V.14
-
11
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R. 2005. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352:997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
De Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
12
-
-
9144256125
-
The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites
-
Hermann A, Goyal R, Jeltsch A. 2004. The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites. J Biol Chem 279:48350-48359.
-
(2004)
J Biol Chem
, vol.279
, pp. 48350-48359
-
-
Hermann, A.1
Goyal, R.2
Jeltsch, A.3
-
13
-
-
77949546881
-
Impact of genomic methylation on radiation sensitivity of colorectal carcinoma
-
Hofstetter B, Niemierko A, Forrer C, Benhattar J, Albertini V, Pruschy M, Bosman FT, Catapano CV, Ciernik IF. 2010. Impact of genomic methylation on radiation sensitivity of colorectal carcinoma. Int J Radiat Oncol Biol Phys 76:1512-1519.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.76
, pp. 1512-1519
-
-
Hofstetter, B.1
Niemierko, A.2
Forrer, C.3
Benhattar, J.4
Albertini, V.5
Pruschy, M.6
Bosman, F.T.7
Catapano, C.V.8
Ciernik, I.F.9
-
14
-
-
84898669639
-
5-Azacytidine enhances the radiosensitivity of CNE2 and SUNE1 cells in vitro and in vivo possibly by altering DNA methylation
-
Jiang W, Li YQ, Liu N, Sun Y, He QM, Jiang N, Xu YF, Chen L, Ma J. 2014. 5-Azacytidine enhances the radiosensitivity of CNE2 and SUNE1 cells in vitro and in vivo possibly by altering DNA methylation. PLoS One 9:e93273.
-
(2014)
PLoS One
, vol.9
, pp. e93273
-
-
Jiang, W.1
Li, Y.Q.2
Liu, N.3
Sun, Y.4
He, Q.M.5
Jiang, N.6
Xu, Y.F.7
Chen, L.8
Ma, J.9
-
16
-
-
40449104358
-
Transient cyclical methylation of promoter DNA
-
Kangaspeska S, Stride B, Metivier R, Polycarpou-Schwarz M, Ibberson D, Carmouche RP, Benes V, Gannon F, Reid G. 2008. Transient cyclical methylation of promoter DNA. Nature 452:112-115.
-
(2008)
Nature
, vol.452
, pp. 112-115
-
-
Kangaspeska, S.1
Stride, B.2
Metivier, R.3
Polycarpou-Schwarz, M.4
Ibberson, D.5
Carmouche, R.P.6
Benes, V.7
Gannon, F.8
Reid, G.9
-
17
-
-
84862828219
-
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity
-
Kim HJ, Kim JH, Chie EK, Young PD, Kim IA, Kim IH. 2012. DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity. Radiat Oncol 7:39.
-
(2012)
Radiat Oncol
, vol.7
, pp. 39
-
-
Kim, H.J.1
Kim, J.H.2
Chie, E.K.3
Young, P.D.4
Kim, I.A.5
Kim, I.H.6
-
18
-
-
77955924030
-
Global analysis of CpG methylation reveals epigenetic control of the radiosensitivity in lung cancer cell lines
-
Kim EH, Park AK, Dong SM, Ahn JH, Park WY. 2010. Global analysis of CpG methylation reveals epigenetic control of the radiosensitivity in lung cancer cell lines. Oncogene 29:4725-4731.
-
(2010)
Oncogene
, vol.29
, pp. 4725-4731
-
-
Kim, E.H.1
Park, A.K.2
Dong, S.M.3
Ahn, J.H.4
Park, W.Y.5
-
19
-
-
80655144416
-
DNA methylation changes in cells regrowing after fractioned ionizing radiation
-
Kuhmann C, Weichenhan D, Rehli M, Plass C, Schmezer P, Popanda O. 2011. DNA methylation changes in cells regrowing after fractioned ionizing radiation. Radiother Oncol 101:116-121.
-
(2011)
Radiother Oncol
, vol.101
, pp. 116-121
-
-
Kuhmann, C.1
Weichenhan, D.2
Rehli, M.3
Plass, C.4
Schmezer, P.5
Popanda, O.6
-
20
-
-
84866421124
-
Gamma Irradiation Does Not Induce Detectable Changes in DNA Methylation Directly following Exposure of Human Cells
-
Lahtz C, Bates SE, Jiang Y, Li AX, Wu X, Hahn MA, Pfeifer GP. 2012. Gamma Irradiation Does Not Induce Detectable Changes in DNA Methylation Directly following Exposure of Human Cells. PLoS One 7:e44858.
-
(2012)
PLoS One
, vol.7
, pp. e44858
-
-
Lahtz, C.1
Bates, S.E.2
Jiang, Y.3
Li, A.X.4
Wu, X.5
Hahn, M.A.6
Pfeifer, G.P.7
-
21
-
-
84897888307
-
Development of TRAIL resistance by radiation-induced hypermethylation of DR4 CpG island in recurrent laryngeal squamous cell carcinoma
-
Lee JC, Lee WH, Min YJ, Cha HJ, Han MW, Chang HW, Kim SA, Choi SH, Kim SW, Kim SY. 2014. Development of TRAIL resistance by radiation-induced hypermethylation of DR4 CpG island in recurrent laryngeal squamous cell carcinoma. Int J Radiat Oncol Biol Phys 88:1203-1211.
-
(2014)
Int J Radiat Oncol Biol Phys
, vol.88
, pp. 1203-1211
-
-
Lee, J.C.1
Lee, W.H.2
Min, Y.J.3
Cha, H.J.4
Han, M.W.5
Chang, H.W.6
Kim, S.A.7
Choi, S.H.8
Kim, S.W.9
Kim, S.Y.10
-
22
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
Metivier R, Gallais R, Tiffoche C, Le Peron C, Jurkowska RZ, Carmouche RP, Ibberson D, Barath P, Demay F, Reid G, Benes V, Jeltsch A, Gannon F, Salbert G. 2008. Cyclical DNA methylation of a transcriptionally active promoter. Nature 452:45-50.
-
(2008)
Nature
, vol.452
, pp. 45-50
-
-
Metivier, R.1
Gallais, R.2
Tiffoche, C.3
Le Peron, C.4
Jurkowska, R.Z.5
Carmouche, R.P.6
Ibberson, D.7
Barath, P.8
Demay, F.9
Reid, G.10
Benes, V.11
Jeltsch, A.12
Gannon, F.13
Salbert, G.14
-
23
-
-
65649108096
-
Additive effects of 5-aza-2′-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines
-
Patties I, Jahns J, Hildebrandt G, Kortmann RD, Glasow A. 2009. Additive effects of 5-aza-2′-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines. Strahlenther Onkol 185:331-338.
-
(2009)
Strahlenther Onkol
, vol.185
, pp. 331-338
-
-
Patties, I.1
Jahns, J.2
Hildebrandt, G.3
Kortmann, R.D.4
Glasow, A.5
-
24
-
-
27644503129
-
Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus
-
Pogribny I, Koturbash I, Tryndyak V, Hudson D, Stevenson SM, Sedelnikova O, Bonner W, Kovalchuk O. 2005. Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus. Mol Cancer Res 3:553-561.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 553-561
-
-
Pogribny, I.1
Koturbash, I.2
Tryndyak, V.3
Hudson, D.4
Stevenson, S.M.5
Sedelnikova, O.6
Bonner, W.7
Kovalchuk, O.8
-
25
-
-
3142703591
-
Dose-dependence, sexand tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes
-
Pogribny I, Raiche J, Slovack M, Kovalchuk O. 2004. Dose-dependence, sexand tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes. Biochem Biophys Res Commun 320:1253-1261.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 1253-1261
-
-
Pogribny, I.1
Raiche, J.2
Slovack, M.3
Kovalchuk, O.4
-
26
-
-
58149313656
-
DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells
-
Qiu H, Yashiro M, Shinto O, Matsuzaki T, Hirakawa K. 2009. DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells. Cancer Sci 100:181-188.
-
(2009)
Cancer Sci
, vol.100
, pp. 181-188
-
-
Qiu, H.1
Yashiro, M.2
Shinto, O.3
Matsuzaki, T.4
Hirakawa, K.5
-
27
-
-
34250869019
-
MDA-MB-435 cells are derived from M14 melanoma cells-a loss for breast cancer, but a boon for melanoma research
-
Rae JM, Creighton CJ, Meck JM, Haddad BR, Johnson MD. 2007. MDA-MB-435 cells are derived from M14 melanoma cells-a loss for breast cancer, but a boon for melanoma research. Breast Cancer Res Treat 104:13-19.
-
(2007)
Breast Cancer Res Treat
, vol.104
, pp. 13-19
-
-
Rae, J.M.1
Creighton, C.J.2
Meck, J.M.3
Haddad, B.R.4
Johnson, M.D.5
-
28
-
-
79954416175
-
DNA hypermethylation as a chemotherapy target
-
Ren J, Singh BN, Huang Q, Li Z, Gao Y, Mishra P, Hwa YL, Li J, Dowdy SC, Jiang SW. 2011. DNA hypermethylation as a chemotherapy target. Cell Signal 23:1082-1093.
-
(2011)
Cell Signal
, vol.23
, pp. 1082-1093
-
-
Ren, J.1
Singh, B.N.2
Huang, Q.3
Li, Z.4
Gao, Y.5
Mishra, P.6
Hwa, Y.L.7
Li, J.8
Dowdy, S.C.9
Jiang, S.W.10
-
29
-
-
84881297457
-
ATM mediates pRB function to control DNMT1 protein stability and DNA methylation
-
Shamma A, Suzuki M, Hayashi N, Kobayashi M, Sasaki N, Nishiuchi T, Doki Y, Okamoto T, Kohno S, Muranaka H, Kitajima S, Yamamoto K, Takahashi C. 2013. ATM mediates pRB function to control DNMT1 protein stability and DNA methylation. Mol Cell Biol 33:3113-3124.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 3113-3124
-
-
Shamma, A.1
Suzuki, M.2
Hayashi, N.3
Kobayashi, M.4
Sasaki, N.5
Nishiuchi, T.6
Doki, Y.7
Okamoto, T.8
Kohno, S.9
Muranaka, H.10
Kitajima, S.11
Yamamoto, K.12
Takahashi, C.13
-
30
-
-
33645086120
-
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines
-
Stresemann C, Brueckner B, Musch T, Stopper H, Lyko F. 2006. Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res 66:2794-2800.
-
(2006)
Cancer Res
, vol.66
, pp. 2794-2800
-
-
Stresemann, C.1
Brueckner, B.2
Musch, T.3
Stopper, H.4
Lyko, F.5
-
31
-
-
43949136445
-
Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine
-
Stresemann C, Lyko F. 2008. Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine. Int J Cancer 123:8-13.
-
(2008)
Int J Cancer
, vol.123
, pp. 8-13
-
-
Stresemann, C.1
Lyko, F.2
-
32
-
-
0005223568
-
Effects of X-ray irradiation on genomic DNA methylation levels in mouse tissues
-
Tawa R, Kimura Y, Komura J, Miyamura Y, Kurishita A, Sasaki MS, Sakurai H, Ono T. 1998. Effects of X-ray irradiation on genomic DNA methylation levels in mouse tissues. J Radiat Res 39:271-278.
-
(1998)
J Radiat Res
, vol.39
, pp. 271-278
-
-
Tawa, R.1
Kimura, Y.2
Komura, J.3
Miyamura, Y.4
Kurishita, A.5
Sasaki, M.S.6
Sakurai, H.7
Ono, T.8
-
33
-
-
84872189951
-
5-aza-2′-Deoxycytidine enhances the radiosensitivity of breast cancer cells
-
Wang L, Zhang Y, Li R, Chen Y, Pan X, Li G, Dai F, Yang J. 2013. 5-aza-2′-Deoxycytidine enhances the radiosensitivity of breast cancer cells. Cancer Biother Radiopharm 28:34-44.
-
(2013)
Cancer Biother Radiopharm
, vol.28
, pp. 34-44
-
-
Wang, L.1
Zhang, Y.2
Li, R.3
Chen, Y.4
Pan, X.5
Li, G.6
Dai, F.7
Yang, J.8
-
34
-
-
84897550124
-
Genome-wide screen of DNA methylation changes induced by low dose Xray radiation in mice
-
Wang J, Zhang Y, Xu K, Mao X, Xue L, Liu X, Yu H, Chen L, Chu X. 2014. Genome-wide screen of DNA methylation changes induced by low dose Xray radiation in mice. PLoS One 9:e90804.
-
(2014)
PLoS One
, vol.9
, pp. e90804
-
-
Wang, J.1
Zhang, Y.2
Xu, K.3
Mao, X.4
Xue, L.5
Liu, X.6
Yu, H.7
Chen, L.8
Chu, X.9
-
35
-
-
84055182550
-
Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell
-
Yu W, Jin C, Lou X, Han X, Li L, He Y, Zhang H, Ma K, Zhu J, Cheng L, Lin B. 2011. Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell. PLoS One 6:e29450.
-
(2011)
PLoS One
, vol.6
, pp. e29450
-
-
Yu, W.1
Jin, C.2
Lou, X.3
Han, X.4
Li, L.5
He, Y.6
Zhang, H.7
Ma, K.8
Zhu, J.9
Cheng, L.10
Lin, B.11
|