Effects of X-ray Irradiation on Genomic DNA Methylation Levels in Mouse Tissues

Journal of Radiation Research

Volumn 39, Issue 4, 1998, Pages 271-278

  Tawa, Riichi ^a   Kimura, Yutaka ^b,c   Komura, Jun Ichiro ^b   Miyamura, Yoshinori ^b,d   Kurishita, Akihiro ^e   Sasaki, Masao S ^f   Sakurai, Hiromu ^a   Ono, Tetsuya ^b  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e Far East Inc ^*  (Japan)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

5 methyldeoxycytidine; Demethylation; HPLC; Tissues; X rays

Indexed keywords

DNA; GENES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; IONIZING RADIATION; IRRADIATION; MAMMALS; METHYLATION; RADIATION EFFECTS; TISSUE;

5-METHYLDEOXYCYTIDINE; CELL/B.E; CULTURED CELL; DEMETHYLATION; DNA METHYLATION; GENOMIC DNA; HPLC; MOUSE TISSUES; TISSUE; X RAY IRRADIATION;

ALKYLATION;

ANIMAL; ARTICLE; BRAIN; BRAIN LEVEL; CELL CULTURE; CHEMISTRY; DNA METHYLATION; GENOME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; MOUSE; RADIATION EXPOSURE; SPLEEN;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA METHYLATION; GENOME; LIVER; MICE; SPLEEN;

EID: 0005223568     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.39.271     Document Type: Article

References (34)

1. Bird, A. (1992) The essentials of DNA methylation. Cell 70: 5-8.
2. Singer-Sam, J., Goldstein, L., Dai, A., Gartler, S. M. and Riggs, A. D. (1992) A potentially critical HpaII site of the X chromosome-linked PGK1 gene is unmethylated prior to the onset of meiosis of human oogenic cells. Proc. Natl. Acad. Sci. USA 89: 1413-1417.
3. Jones, P. L., Veenstra, G. J. C., Wade, P. A., Vermaak, D., Kass, S. U., Landsberger, N., Strouboulis, J. and Wolffe, A.P. (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nature Genet. 19: 187-191.
4. Razin, A., Webb, C., Szyf, M., Yisraeli, J., Rosenthal, A., Naveh-Many, T., Sciaky-Gallili, N. and Cedar, H. (1984) Variations in DNA methylation during mouse cell differentiation in vivo and in vitro. Proc. Natl. Acad. Sci. USA 81: 2275-2279.
5. Razin, A., Szyf, M., Kafri, T., Roll, M., Giloh, H., Scarpa, S., Carotti, D. and Cantoni, G. L. (1986) Replacement of 5-methylcytosine by cytosine: A possible mechanism for transient DNA demethylation during differentiation. Proc. Natl. Acad. Sci. USA 83: 2827-2831.
6. Turker, M. S. and Bestor, T. H. (1997) Formation of methylation patterns in the mammalian genome. Mutat. Res. 386: 119-130.
7. Tawa, R., Ono, T., Kurishita, A., Okada, S. and Hirose, S. (1990) Changes of DNA methylation level during pre- and postnatal periods in mice. Differential. 45: 44-48.
8. Feinberg, A. P. and Vogelstein, B. (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301: 89-92.
9. Counts, J. L. and Goodman, J. I. (1995) Alterations in DNA methylation may play a variety of roles in carcinogenesis. Cell 83: 13-15.
10. Kastan, M. B., Gowans, B. J. and Lieberman, M. W. (1982) Methylation of deoxycytidine incorporated by excision-repair synthesis of DNA. Cell 30: 509-516.
11. Wilson, V. L. and Jones, P. A. (1983) Inhibition of DNA methylation by chemical carcinogens in vitro. Cell 32: 239-246.
12. Lieberman, M. W., Beach, L. R. and Palmiter, R. D. (1983) Ultraviolet radiation-induced metallothionein-i gene activation is associated with extensive DNA demethylation. Cell 35: 207-214.
13. Boehm, T. L. J., Grunberger, D. and Drahovsky, D. (1983) Aberrant de novo methylation of DNA after treatment of murine cells with N-acetoxy-N-2-acetylaminofluorene. Cancer Res. 43: 6066-6071.
14. Barr, F. G., Rajagopalan, S., MacArthur, C. A. and Lieberman, M. W. (1986) Genomic hypomethylation and far-5' sequence alterations are associated with carcinogen-induced activation of the hamster thymidine kinase gene. Mol. Cell. Biol. 6: 3023-3033.
15. Wilson, V. L., Smith, R. A., Longoria, J., Liotta, M. A., Harper, C. M. and Harris, C. C. (1987) Chemical carcinogen-induced decreases in genomic 5-methyldeoxycytidine content of normal human bronchial epithelial cells. Proc. Natl. Acad. Sci. USA 84: 3298-3301.
16. Lehmann, A. R., Arlett, C. F., Harcourt, S. A., Steingrimsdottir, H. and Gebara, M. M. (1989) Mutagenic treatments result in inactivation of expression of a transfected bacterial gene integrated into a human cell line. Mutat. Res. 220: 255-262.
17. Kalinich, J. F., Catravas, G. N. and Snyder, S. L. (1989) The effect of γ radiation on DNA methylation. Radiat. Res. 117: 185-197.
18. Miyamura, Y., Ohtsu, H., Niwa, O., Kurishita, A., Watanabe, M., Sado, T. and Ono, T. (1993) Comparison of the age- and tumor-associated changes in the c-myc gene methylation in mouse liver. Gerontology 39 (suppl 1): 3-10.
19. Yasuzawa, K., Kodama, S., Kato, M., Uehara, Y., Tawa, R., Hirose, S., Sasaki, M. S., Okada, S. and Ono, T. (1992) Changes of DNA methylation in protooncogenes in the process of radiation-induced transformation of mouse m5S/ 1M cells in vitro. Cancer Letters 67: 157-166.
20. Sasaki, M. S. and Kodama, S. (1987) Establishment and some mutational characteristics of 3T3-like near-diploid mouse cell line. J. Cell. Physiol. 131: 114-122.
21. Kodama, S. and Sasaki, M. S. (1987) The involvement of chromosome 13 in the X-ray-induced in vitro transformation of mouse m5S cells. Jpn. J. Cancer Res. 78: 372-381.
22. Kodama, S., Okumura, Y., Komatsu, K. and Sasaki, M. S. (1991) Appearance and evolution of the specific chromosomal rearrangements associated with malignant transformation of mouse m5S cells. Cancer Genet. Cytogenet. 53: 185-197.
23. Hosoi, Y., Kurishita, A., Ono, T. and Sakamoto, K. (1992) Effect of recombinant human granulocyte colony-stimulating factor on survival in lethally irradiated mice. Acta Oncologia 31: 59-63.
24. Ono, T., Okada, S., Kawakami, T., Honjo, T. and Getz, M.J. (1985) Absence of gross change in primary DNA sequence during aging process of mice. Mech. Ageing Dev. 32: 227-234.
25. Nyce, J., Liu, L. and Jones, P. A. (1986) Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells. Nucl. Acids Res. 14: 4353-4367.
26. Ono, T. and Okada, S. (1974) Estimation in vivo of DNA strand breaks and their rejoining in thymus and liver of mouse. Int. J. Radiat. Biol. 25: 291-301.
27. Ward, J. F. (1988) DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and reparability. Prog. Nucl. Acids. Mol. Biol. 35: 95-125.
28. Yamamoto, K., Uraki, F., Yonei, S. and Yukawa, O. (1997) Enzymatic repair mechanisms for base modifications induced by oxygen radicals. J. Radiat. Res. 38: 1-4.
29. Friedberg, E. C. (1985) Excision repair. IV. Postincision events and mismatch repair in mammalian cells. In: DNA Repair, pp. 323-374, W. H. Freeman and Co., New York.
30. Ono, T., Yamamoto, S., Kurishita, A., Yamamoto, K., Yamamoto, Y., Ujeno, Y., Sagisaka, K., Fukui, Y., Miyamoto, M., Tawa, R., Hirose, S. and Okada, S. (1990) Comparison of age-associated changes of c-myc gene methylation in liver between man and mouse. Mutat. Res. 237: 239-246.
31. Ono, T., Shinya, K., Uehara, Y. and Okada, S. (1989) Endogenous virus genomes become hypomethylated tissue-specifically during aging process of C57BL mice. Mech. Ageing Dev. 50: 27-36.
32. Jost, J. P., Siegmann, M., Sun, L. and Leung, R. (1995) Mechanisms of DNA demethylation in chicken embryos. J. Biol. Chem. 270: 9734-9739.
33. Vairapandi, M. and Duker, N. J. (1996) Partial purification and characterization of human 5-methylcytosine-DNA glycosylase. Oncogene 13: 933-938.
34. Weiss, A., Keshet, I., Razin, A. and Cedar, H. (1996) DNA demethylation in vitro: Involvement of RNA. Cell 86: 709-718.