Calcium ions promote primary renal epithelial cell differentiation into cells with bone-associated phenotypes via transforming growth factor-β1-induced epithelial-mesenchymal transition in idiopathic hypercalciuria patients

Molecular Medicine Reports

Volumn 11, Issue 3, 2015, Pages 2199-2206

  He, Deng ^a   Wang, Shaogang ^a   Jia, Zhaohui ^a   Cui, Lei ^a   Lu, Yuchao ^a   Hu, Henglong ^a   Qin, Baolong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Idiopathic hypercalciuria; Renal tubular epithelial cell; Transforming growth factor 1

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CALCITRIOL RECEPTOR; CALCIUM ION; MESSENGER RNA; OSTEOPONTIN; TRANSFORMING GROWTH FACTOR BETA1; CALCIUM;

ADULT; ARTICLE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IDIOPATHIC HYPERCALCIURIA; KIDNEY TUBULE CELL; NEPHROLITHIASIS; PHENOTYPE; PRIMARY CELL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; BLOOD; BONE; CASE CONTROL STUDY; CELL LINE; CELL TRANSDIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; FEMALE; GENETICS; HYPERCALCIURIA; KIDNEY; MALE; METABOLISM; MIDDLE AGED; YOUNG ADULT;

ADULT; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 2; CALCIUM; CASE-CONTROL STUDIES; CELL LINE; CELL TRANSDIFFERENTIATION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; HUMANS; HYPERCALCIURIA; KIDNEY; MALE; MIDDLE AGED; NEPHROLITHIASIS; OSTEOPONTIN; PHENOTYPE; TRANSFORMING GROWTH FACTOR BETA1; YOUNG ADULT;

EID: 84916613625     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2941     Document Type: Article

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