-
1
-
-
20144363712
-
A potential decline in life expectancy in the United States in the 21st century
-
Olshansky SJ, Passaro DJ, Hershow RC, et al. A potential decline in life expectancy in the United States in the 21st century. N Engl J Med. 2005;352:1138-1145.
-
(2005)
N Engl J Med
, vol.352
, pp. 1138-1145
-
-
Olshansky, S.J.1
Passaro, D.J.2
Hershow, R.C.3
-
2
-
-
27844483012
-
Childhood obesity and type 2 diabetes mellitus
-
Hannon TS, Rao G, Arslanian SA. Childhood obesity and type 2 diabetes mellitus. Pediatrics. 2005;116:473-480.
-
(2005)
Pediatrics
, vol.116
, pp. 473-480
-
-
Hannon, T.S.1
Rao, G.2
Arslanian, S.A.3
-
3
-
-
61849142246
-
Prevalence of pre-diabetes and its association with clustering of cardiometabolic risk factors and hyperinsulinemia among US adolescents: NHANES 2005-2006
-
Li C, Ford ES, Zhao G, Mokdad AH. Prevalence of pre-diabetes and its association with clustering of cardiometabolic risk factors and hyperinsulinemia among US adolescents: NHANES 2005-2006. Diabetes Care. 2009;32:342-347.
-
(2009)
Diabetes Care
, vol.32
, pp. 342-347
-
-
Li, C.1
Ford, E.S.2
Zhao, G.3
Mokdad, A.H.4
-
4
-
-
78650053173
-
Insulin resistance in children: Consensus, perspective, and future directions
-
Levy-Marchal C, Arslanian S, Cutfield W, et al. ESPE-LWPES-ISPAD-APPES-APEG-SLEP-JSPE; Insulin Resistance in Children Consensus Conference Group. Insulin resistance in children: consensus, perspective, and future directions. J Clin Endocrinol Metab. 2010;95:5189-5198.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 5189-5198
-
-
Levy-Marchal, C.1
Arslanian, S.2
Cutfield, W.3
ESPE-LWPES-ISPAD-APPES-APEG-SLEP-JSPE4
-
5
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-419.
-
(1985)
Diabetologia
, vol.28
, Issue.7
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
6
-
-
2342509057
-
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole animal insulin resistance
-
An J, Muoio DM, Shiota M, et al. Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole animal insulin resistance. Nat Med. 2004;10:268-274.
-
(2004)
Nat Med
, vol.10
, pp. 268-274
-
-
An, J.1
Muoio, D.M.2
Shiota, M.3
-
7
-
-
0025129387
-
Tandem mass spectrometry: A new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism
-
Millington DS, Kodo N, Norwood DL, Roe CR. Tandem mass spectrometry: a new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism. J Inherit Metab Dis. 1990;13:321-324.
-
(1990)
J Inherit Metab Dis
, vol.13
, pp. 321-324
-
-
Millington, D.S.1
Kodo, N.2
Norwood, D.L.3
Roe, C.R.4
-
8
-
-
85047690932
-
ENU mutagenesis identifies mice with mitochondrial branched chain aminotransferase deficiency resembling human maple syrup urine disease
-
Wu JY, Kao HJ, Li SC, et al. ENU mutagenesis identifies mice with mitochondrial branched chain aminotransferase deficiency resembling human maple syrup urine disease. J Clin Invest. 2004;113:434-440.
-
(2004)
J Clin Invest
, vol.113
, pp. 434-440
-
-
Wu, J.Y.1
Kao, H.J.2
Li, S.C.3
-
9
-
-
0028895728
-
Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry
-
Chace DH, Hillman SL, Millington DS, Kahler SG, Roe CR, Naylor EW. Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry. Clin Chem. 1995;41:62-68.
-
(1995)
Clin Chem
, vol.41
, pp. 62-68
-
-
Chace, D.H.1
Hillman, S.L.2
Millington, D.S.3
Kahler, S.G.4
Roe, C.R.5
Naylor, E.W.6
-
10
-
-
41949105208
-
Genetic network of liver metabolism revealed by integration of metabolic and transcriptional profiling
-
Ferrara CT, Wang P, Neto EC, et al. Genetic network of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet. 2008;4(3):e1000034.
-
(2008)
PLoS Genet
, vol.4
, Issue.3
, pp. e1000034
-
-
Ferrara, C.T.1
Wang, P.2
Neto, E.C.3
-
12
-
-
63449111894
-
A branched-chain amino acidrelated metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
-
Newgard CB, An J, Bain JR, et al. A branched-chain amino acidrelated metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab. 2009;9(4):311-326.
-
(2009)
Cell Metab
, vol.9
, Issue.4
, pp. 311-326
-
-
Newgard, C.B.1
An, J.2
Bain, J.R.3
-
13
-
-
70350560562
-
Metabolomics applied to diabetes research: Moving from information to knowledge
-
Bain JR, Stevens RD, Wenner BR, Ilkayeva O, Muoio DM, Newgard CB. Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes. 2009;58:2429-2443.
-
(2009)
Diabetes
, vol.58
, pp. 2429-2443
-
-
Bain, J.R.1
Stevens, R.D.2
Wenner, B.R.3
Ilkayeva, O.4
Muoio, D.M.5
Newgard, C.B.6
-
14
-
-
79953737332
-
Metabolite profiles and the risk of developing diabetes
-
Wang TJ, Larson MG, Vasan RS, et al. Metabolite profiles and the risk of developing diabetes. Nat Med. 2011;17(4):448-453.
-
(2011)
Nat Med
, vol.17
, Issue.4
, pp. 448-453
-
-
Wang, T.J.1
Larson, M.G.2
Vasan, R.S.3
-
15
-
-
84879550459
-
Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness
-
Batch BC, Shah SH, Newgard CB, et al. Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness. Metabolism. 2013;62(7):961-969.
-
(2013)
Metabolism
, vol.62
, Issue.7
, pp. 961-969
-
-
Batch, B.C.1
Shah, S.H.2
Newgard, C.B.3
-
16
-
-
77953667219
-
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events
-
Shah SH, Bain JR, Muehlbauer MJ, et al. Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet. 2010;3(2):207-214.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, Issue.2
, pp. 207-214
-
-
Shah, S.H.1
Bain, J.R.2
Muehlbauer, M.J.3
-
17
-
-
84873032392
-
Targeted metabolomics finds its mark in diabetes research
-
Bain JR. Targeted metabolomics finds its mark in diabetes research. Diabetes. 2013;62(2):349-351.
-
(2013)
Diabetes
, vol.62
, Issue.2
, pp. 349-351
-
-
Bain, J.R.1
-
18
-
-
84859073302
-
Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: Evidence for enhanced mitochondrial oxidation
-
Mihalik SJ, Michaliszyn SF, de las Heras J, et al. Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: evidence for enhanced mitochondrial oxidation. Diabetes Care. 2012;35(3):605-611.
-
(2012)
Diabetes Care
, vol.35
, Issue.3
, pp. 605-611
-
-
Mihalik, S.J.1
Michaliszyn, S.F.2
De Las Heras, J.3
-
19
-
-
84868628375
-
Metabolomic profiling of amino acids and β-cell function relative to insulin sensitivity in youth
-
Michaliszyn SF, Sjaarda LA, Mihalik SJ, et al. Metabolomic profiling of amino acids and β-cell function relative to insulin sensitivity in youth. J Clin Endocrinol Metab. 2012;97(11):E2119-E2124.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, Issue.11
, pp. E2119-E2124
-
-
Michaliszyn, S.F.1
Sjaarda, L.A.2
Mihalik, S.J.3
-
20
-
-
84874800752
-
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents
-
McCormack SE, Shaham O, McCarthy MA, et al. Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents. Pediatr Obes. 2013;8:52-61.
-
(2013)
Pediatr Obes
, vol.8
, pp. 52-61
-
-
McCormack, S.E.1
Shaham, O.2
McCarthy, M.A.3
-
21
-
-
38349006256
-
Current approaches for assessing insulin sensitivity and resistance in vivo: Advantages, limitations, and appropriate usage
-
Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab. 2008;294(1):E15-E26.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, Issue.1
, pp. E15-E26
-
-
Muniyappa, R.1
Lee, S.2
Chen, H.3
Quon, M.J.4
-
23
-
-
33845592201
-
Adipose tissue-derived factors: Impact on health and disease
-
Trujillo ME, Scherer PE. Adipose tissue-derived factors: impact on health and disease. Endocr Rev. 2006;27(7):762-778.
-
(2006)
Endocr Rev
, vol.27
, Issue.7
, pp. 762-778
-
-
Trujillo, M.E.1
Scherer, P.E.2
-
24
-
-
13244284806
-
Adiponectin-journey from an adipocyte secretory protein to biomarker of the metabolic syndrome
-
Trujillo ME, Scherer PE. Adiponectin-journey from an adipocyte secretory protein to biomarker of the metabolic syndrome. J Intern Med. 2005;257(2):167-175.
-
(2005)
J Intern Med
, vol.257
, Issue.2
, pp. 167-175
-
-
Trujillo, M.E.1
Scherer, P.E.2
-
25
-
-
33751512005
-
Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome
-
Winer JC, Zern TL, Taksali SE, et al. Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome. J Clin Endocrinol Metab. 2006;91:4415-4423.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4415-4423
-
-
Winer, J.C.1
Zern, T.L.2
Taksali, S.E.3
-
26
-
-
84855993248
-
The triglyceride-to-HDL cholesterol ratio: Association with insulin resistance in obese youths of different ethnic backgrounds
-
Giannini C, Santoro N, Caprio S, et al. The triglyceride-to-HDL cholesterol ratio: association with insulin resistance in obese youths of different ethnic backgrounds. Diabetes Care. 2011;34(8):1869-1874.
-
(2011)
Diabetes Care
, vol.34
, Issue.8
, pp. 1869-1874
-
-
Giannini, C.1
Santoro, N.2
Caprio, S.3
-
27
-
-
84860439210
-
Interplay between lipids and branched chain amino acids in development of insulin resistance
-
Newgard CB. Interplay between lipids and branched chain amino acids in development of insulin resistance. Cell Metab. 2012;15:606-614.
-
(2012)
Cell Metab
, vol.15
, pp. 606-614
-
-
Newgard, C.B.1
-
28
-
-
39749147110
-
Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
-
Muoio DM, Newgard CB. Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol. 2008;9:193-205.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 193-205
-
-
Muoio, D.M.1
Newgard, C.B.2
-
29
-
-
25844432311
-
Peroxisomal proliferator-activated receptor-γ co-activator 1α-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency
-
Koves TR, Li P, An J, et al. Peroxisomal proliferator-activated receptor-γ co-activator 1α-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem. 2005;280:33588-33598.
-
(2005)
J Biol Chem
, vol.280
, pp. 33588-33598
-
-
Koves, T.R.1
Li, P.2
An, J.3
-
30
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves TR, Ussher JR, Noland RC, et al. Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab. 2008;7:45-56.
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
-
31
-
-
84876539834
-
"Prediction is very hard, especially about the future": New biomarkers for type 2 diabetes?
-
Lowe WL Jr, Bain JR. "Prediction is very hard, especially about the future": new biomarkers for type 2 diabetes? Diabetes. 2013;62(5):1384-1385.
-
(2013)
Diabetes
, vol.62
, Issue.5
, pp. 1384-1385
-
-
Lowe, W.L.1
Bain, J.R.2
-
32
-
-
84876575039
-
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance
-
Ferrannini E, Natali A, Camastra S, et al. Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance. Diabetes. 2013;62:1730-1737.
-
(2013)
Diabetes
, vol.62
, pp. 1730-1737
-
-
Ferrannini, E.1
Natali, A.2
Camastra, S.3
-
33
-
-
0033749264
-
Increased adipose tissue in male and female estrogen receptor-α knockout mice
-
7
-
Heine PA, Taylor JA, Iwamoto GA, Lubahn DB, Cooke PS. Increased adipose tissue in male and female estrogen receptor-α knockout mice. Proc Natl Acad Sci USA. 2000 7;97(23):12729-12734.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.23
, pp. 12729-12734
-
-
Heine, P.A.1
Taylor, J.A.2
Iwamoto, G.A.3
Lubahn, D.B.4
Cooke, P.S.5
-
34
-
-
33244495940
-
Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: Insulin sensitivity in the liver
-
Bryzgalova G1, Gao H, Ahren B, et al. Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver. Diabetologia. 2006;49(3):588-597.
-
(2006)
Diabetologia
, vol.49
, Issue.3
, pp. 588-597
-
-
Bryzgalova, G.1
Gao, H.2
Ahren, B.3
-
35
-
-
33751245563
-
Longitudinal study of physiologic insulin resistance and metabolic changes of puberty
-
Hannon TS, Janosky J, Arslanian SA. Longitudinal study of physiologic insulin resistance and metabolic changes of puberty. Pediatr Res. 2006;60(6):759-763.
-
(2006)
Pediatr Res
, vol.60
, Issue.6
, pp. 759-763
-
-
Hannon, T.S.1
Janosky, J.2
Arslanian, S.A.3
-
36
-
-
0035512070
-
Longitudinal study on pubertal insulin resistance
-
Goran MI, Gower BA. Longitudinal study on pubertal insulin resistance. Diabetes. 2001;50(11):2444-2450.
-
(2001)
Diabetes
, vol.50
, Issue.11
, pp. 2444-2450
-
-
Goran, M.I.1
Gower, B.A.2
-
37
-
-
65549091789
-
Sexual dimorphism of body composition and insulin sensitivity across pubertal development in obese Caucasian subjects
-
Brufani C, Tozzi A, Fintini D, et al. Sexual dimorphism of body composition and insulin sensitivity across pubertal development in obese Caucasian subjects. Eur J Endocrinol. 2009;160(5):769-775.
-
(2009)
Eur J Endocrinol
, vol.160
, Issue.5
, pp. 769-775
-
-
Brufani, C.1
Tozzi, A.2
Fintini, D.3
-
38
-
-
69549097700
-
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women
-
Huffman KM, Shah SH, Stevens RD, et al. Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. Diabetes Care. 2009;32(9):1678-1683.
-
(2009)
Diabetes Care
, vol.32
, Issue.9
, pp. 1678-1683
-
-
Huffman, K.M.1
Shah, S.H.2
Stevens, R.D.3
-
39
-
-
78650904854
-
TODAY Study Group. Characteristics of adolescents and youth with recent-onset type 2 diabetes: The TODAY cohort at baseline
-
Copeland KC, Zeitler P, Geffner M, et al. TODAY Study Group. Characteristics of adolescents and youth with recent-onset type 2 diabetes: the TODAY cohort at baseline. J Clin Endocrinol Metab. 2011;96(1):159-167.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, Issue.1
, pp. 159-167
-
-
Copeland, K.C.1
Zeitler, P.2
Geffner, M.3
-
40
-
-
84862226987
-
A clinical trial to maintain glycemic control in youth with type 2 diabetes
-
TODAY Study Group. A clinical trial to maintain glycemic control in youth with type 2 diabetes. N Engl J Med. 2012;366(24):2247-2256.
-
(2012)
N Engl J Med
, vol.366
, Issue.24
, pp. 2247-2256
-
-
|