메뉴 건너뛰기




Volumn 16, Issue 11-12, 2014, Pages 364-373

Gene delivery targeted to oligodendrocytes using a lentiviral vector

Author keywords

CNP promoter; EGFP; Gene therapy; Leukodystrophy

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; ENHANCED GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; GREEN FLUORESCENT PROTEIN;

EID: 84916606169     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.2813     Document Type: Article
Times cited : (11)

References (57)
  • 1
    • 64049098693 scopus 로고    scopus 로고
    • Innate immune recognition of viruses and viral vectors
    • Huang X, Yang Y. Innate immune recognition of viruses and viral vectors. Hum Gene Ther 2009; 20: 293-301.
    • (2009) Hum Gene Ther , vol.20 , pp. 293-301
    • Huang, X.1    Yang, Y.2
  • 2
    • 84879041937 scopus 로고    scopus 로고
    • Glial promoter selectivity following AAV-delivery to the immature brain
    • von Jonquieres G, Mersmann N, Klugmann CB, et al. Glial promoter selectivity following AAV-delivery to the immature brain. PLoS One 2013; 8: e65646.
    • (2013) PLoS One , vol.8 , pp. e65646
    • von Jonquieres, G.1    Mersmann, N.2    Klugmann, C.B.3
  • 3
    • 32844456598 scopus 로고    scopus 로고
    • Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain
    • Broekman ML, Comer LA, Hyman BT, et al. Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain. Neuroscience 2006; 138: 501-510.
    • (2006) Neuroscience , vol.138 , pp. 501-510
    • Broekman, M.L.1    Comer, L.A.2    Hyman, B.T.3
  • 4
    • 6944232374 scopus 로고    scopus 로고
    • Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors
    • Consiglio A, Gritti A, Dolcetta D, et al. Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proc Natl Acad Sci U S A 2004; 101: 14835-14840.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14835-14840
    • Consiglio, A.1    Gritti, A.2    Dolcetta, D.3
  • 5
    • 0035099437 scopus 로고    scopus 로고
    • In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice
    • Consiglio A, Quattrini A, Martino S, et al. In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice. Nat Med 2001; 7: 310-316.
    • (2001) Nat Med , vol.7 , pp. 310-316
    • Consiglio, A.1    Quattrini, A.2    Martino, S.3
  • 6
    • 0029993858 scopus 로고    scopus 로고
    • Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
    • Naldini L, Blomer U, Gage FH, et al. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A 1996; 93: 11382-11388.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11382-11388
    • Naldini, L.1    Blomer, U.2    Gage, F.H.3
  • 7
    • 0028169741 scopus 로고
    • Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
    • Kaplitt MG, Leone P, Samulski RJ, et al. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet 1994; 8: 148-154.
    • (1994) Nat Genet , vol.8 , pp. 148-154
    • Kaplitt, M.G.1    Leone, P.2    Samulski, R.J.3
  • 8
    • 77649271981 scopus 로고    scopus 로고
    • Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain
    • Markakis EA, Vives KP, Bober J, et al. Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain. Mol Ther 2010; 18: 588-593.
    • (2010) Mol Ther , vol.18 , pp. 588-593
    • Markakis, E.A.1    Vives, K.P.2    Bober, J.3
  • 9
    • 77953522837 scopus 로고    scopus 로고
    • Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models
    • Lattanzi A, Neri M, Maderna C, et al. Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models. Hum Mol Genet 2010; 19: 2208-2227.
    • (2010) Hum Mol Genet , vol.19 , pp. 2208-2227
    • Lattanzi, A.1    Neri, M.2    Maderna, C.3
  • 10
    • 33745670134 scopus 로고    scopus 로고
    • Lentiviral vectors mediate efficient and stable gene transfer in adult neural stem cells in vivo
    • Geraerts M, Eggermont K, Hernandez-Acosta P, et al. Lentiviral vectors mediate efficient and stable gene transfer in adult neural stem cells in vivo. Hum Gene Ther 2006; 17: 635-650.
    • (2006) Hum Gene Ther , vol.17 , pp. 635-650
    • Geraerts, M.1    Eggermont, K.2    Hernandez-Acosta, P.3
  • 11
    • 84879508240 scopus 로고    scopus 로고
    • Dynamic activity of miR-125b and miR-93 during murine neural stem cell differentiation and in the subventricular zone neurogenic niche
    • Lattanzi A, Gentner B, Corno D, et al. Dynamic activity of miR-125b and miR-93 during murine neural stem cell differentiation and in the subventricular zone neurogenic niche. PLoS One 2013; 8: e67411.
    • (2013) PLoS One , vol.8 , pp. e67411
    • Lattanzi, A.1    Gentner, B.2    Corno, D.3
  • 12
    • 0029849257 scopus 로고    scopus 로고
    • Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
    • Dong JY, Fan PD, Frizzell RA. Quantitative analysis of the packaging capacity of recombinant adeno-associated virus. Hum Gene Ther 1996; 7: 2101-2112.
    • (1996) Hum Gene Ther , vol.7 , pp. 2101-2112
    • Dong, J.Y.1    Fan, P.D.2    Frizzell, R.A.3
  • 13
    • 84877578223 scopus 로고    scopus 로고
    • Progress in gene therapy for neurological disorders
    • Simonato M, Bennett J, Boulis NM, et al. Progress in gene therapy for neurological disorders. Nat Rev Neurol 2013; 9: 277-291.
    • (2013) Nat Rev Neurol , vol.9 , pp. 277-291
    • Simonato, M.1    Bennett, J.2    Boulis, N.M.3
  • 14
    • 0036897235 scopus 로고    scopus 로고
    • Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease
    • Azzouz M, Martin-Rendon E, Barber RD, et al. Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease. J Neurosci 2002; 22: 10302-10312.
    • (2002) J Neurosci , vol.22 , pp. 10302-10312
    • Azzouz, M.1    Martin-Rendon, E.2    Barber, R.D.3
  • 15
    • 60649116702 scopus 로고    scopus 로고
    • Applications of lentiviral vectors for biology and gene therapy of neurological disorders
    • Lundberg C, Bjorklund T, Carlsson T, et al. Applications of lentiviral vectors for biology and gene therapy of neurological disorders. Curr Gene Ther 2008; 8: 461-473.
    • (2008) Curr Gene Ther , vol.8 , pp. 461-473
    • Lundberg, C.1    Bjorklund, T.2    Carlsson, T.3
  • 16
    • 84901292902 scopus 로고    scopus 로고
    • Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy
    • Lattanzi A, Salvagno C, Maderna C, et al. Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy. Hum Mol Genet 2014; 23: 3250-3268.
    • (2014) Hum Mol Genet , vol.23 , pp. 3250-3268
    • Lattanzi, A.1    Salvagno, C.2    Maderna, C.3
  • 17
    • 27644550940 scopus 로고    scopus 로고
    • Lentiviral transduction of murine oligodendrocytes in vivo
    • McIver SR, Lee CS, Lee JM, et al. Lentiviral transduction of murine oligodendrocytes in vivo. J Neurosci Res 2005; 82: 397-403.
    • (2005) J Neurosci Res , vol.82 , pp. 397-403
    • McIver, S.R.1    Lee, C.S.2    Lee, J.M.3
  • 18
    • 0033557611 scopus 로고    scopus 로고
    • Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virus
    • Chen H, McCarty DM, Bruce AT, et al. Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virus. J Neurosci Res 1999; 55: 504-513.
    • (1999) J Neurosci Res , vol.55 , pp. 504-513
    • Chen, H.1    McCarty, D.M.2    Bruce, A.T.3
  • 19
    • 70349850388 scopus 로고    scopus 로고
    • Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates
    • Lawlor PA, Bland RJ, Mouravlev A, et al. Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates. Mol Ther 2009; 17: 1692-1702.
    • (2009) Mol Ther , vol.17 , pp. 1692-1702
    • Lawlor, P.A.1    Bland, R.J.2    Mouravlev, A.3
  • 20
    • 0031904562 scopus 로고    scopus 로고
    • Four-kilobase sequence of the mouse CNP gene directs spatial and temporal expression of lacZ in transgenic mice
    • Gravel M, Di Polo A, Valera PB, et al. Four-kilobase sequence of the mouse CNP gene directs spatial and temporal expression of lacZ in transgenic mice. J Neurosci Res 1998; 53: 393-404.
    • (1998) J Neurosci Res , vol.53 , pp. 393-404
    • Gravel, M.1    Di Polo, A.2    Valera, P.B.3
  • 21
    • 65549112949 scopus 로고    scopus 로고
    • Connexin32 mutations cause loss of function in Schwann cells and oligodendrocytes leading to PNS and CNS myelination defects
    • Sargiannidou I, Vavlitou N, Aristodemou S, et al. Connexin32 mutations cause loss of function in Schwann cells and oligodendrocytes leading to PNS and CNS myelination defects. J Neurosci 2009; 29: 4736-4749.
    • (2009) J Neurosci , vol.29 , pp. 4736-4749
    • Sargiannidou, I.1    Vavlitou, N.2    Aristodemou, S.3
  • 22
    • 0035370760 scopus 로고    scopus 로고
    • A distal upstream enhancer from the myelin basic protein gene regulates expression in myelin-forming schwann cells
    • Forghani R, Garofalo L, Foran DR, et al. A distal upstream enhancer from the myelin basic protein gene regulates expression in myelin-forming schwann cells. J Neurosci 2001; 21: 3780-3787.
    • (2001) J Neurosci , vol.21 , pp. 3780-3787
    • Forghani, R.1    Garofalo, L.2    Foran, D.R.3
  • 23
    • 0034667678 scopus 로고    scopus 로고
    • A transgenic mouse model for inducible and reversible dysmyelination
    • Mathis C, Hindelang C, LeMeur M, et al. A transgenic mouse model for inducible and reversible dysmyelination. J Neurosci 2000; 20: 7698-7705.
    • (2000) J Neurosci , vol.20 , pp. 7698-7705
    • Mathis, C.1    Hindelang, C.2    LeMeur, M.3
  • 24
    • 79960969591 scopus 로고    scopus 로고
    • Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans
    • Tress O, Maglione M, Zlomuzica A, et al. Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans. PLoS Genet 2011; 7: e1002146.
    • (2011) PLoS Genet , vol.7 , pp. e1002146
    • Tress, O.1    Maglione, M.2    Zlomuzica, A.3
  • 25
    • 3242693178 scopus 로고    scopus 로고
    • Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like disease
    • Uhlenberg B, Schuelke M, Ruschendorf F, et al. Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like disease. Am J Hum Genet 2004; 75: 251-260.
    • (2004) Am J Hum Genet , vol.75 , pp. 251-260
    • Uhlenberg, B.1    Schuelke, M.2    Ruschendorf, F.3
  • 26
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • Dull T, Zufferey R, Kelly M, et al. A third-generation lentivirus vector with a conditional packaging system. J Virol 1998; 72: 8463-8471.
    • (1998) J Virol , vol.72 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3
  • 27
    • 84865133559 scopus 로고    scopus 로고
    • Myelination in coculture of established neuronal and Schwann cell lines
    • Sango K, Kawakami E, Yanagisawa H, et al. Myelination in coculture of established neuronal and Schwann cell lines. Histochem Cell Biol 2012; 137: 829-839.
    • (2012) Histochem Cell Biol , vol.137 , pp. 829-839
    • Sango, K.1    Kawakami, E.2    Yanagisawa, H.3
  • 28
    • 0028363067 scopus 로고
    • Differential regulation of the 2',3'-cyclic nucleotide 3'-phosphodiesterase gene during oligodendrocyte development
    • Scherer SS, Braun PE, Grinspan J, et al. Differential regulation of the 2', 3'-cyclic nucleotide 3'-phosphodiesterase gene during oligodendrocyte development. Neuron 1994; 12: 1363-1375.
    • (1994) Neuron , vol.12 , pp. 1363-1375
    • Scherer, S.S.1    Braun, P.E.2    Grinspan, J.3
  • 29
    • 68149181689 scopus 로고    scopus 로고
    • Lentiviral vector-mediated rescue of motor behaviour in spontaneously occurring hereditary ataxic mice
    • Iizuka A, Takayama K, Torashima T, et al. Lentiviral vector-mediated rescue of motor behaviour in spontaneously occurring hereditary ataxic mice. Neurobiol Dis 2009; 35: 457-465.
    • (2009) Neurobiol Dis , vol.35 , pp. 457-465
    • Iizuka, A.1    Takayama, K.2    Torashima, T.3
  • 30
    • 67650239137 scopus 로고    scopus 로고
    • Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain
    • Pilpel N, Landeck N, Klugmann M, et al. Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain. J Neurosci Methods 2009; 182: 55-63.
    • (2009) J Neurosci Methods , vol.182 , pp. 55-63
    • Pilpel, N.1    Landeck, N.2    Klugmann, M.3
  • 31
    • 84897076939 scopus 로고    scopus 로고
    • Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial
    • Palfi S, Gurruchaga JM, Ralph GS, et al. Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial. Lancet 2014; 383: 1138-1146.
    • (2014) Lancet , vol.383 , pp. 1138-1146
    • Palfi, S.1    Gurruchaga, J.M.2    Ralph, G.S.3
  • 32
    • 84874354091 scopus 로고    scopus 로고
    • Patient monitoring and follow-up in lentiviral clinical trials
    • McGarrity GJ, Hoyah G, Winemiller A, et al. Patient monitoring and follow-up in lentiviral clinical trials. J Gene Med 2013; 15: 78-82.
    • (2013) J Gene Med , vol.15 , pp. 78-82
    • McGarrity, G.J.1    Hoyah, G.2    Winemiller, A.3
  • 33
    • 22944458202 scopus 로고    scopus 로고
    • Altering the tropism of lentiviral vectors through pseudotyping
    • Cronin J, Zhang XY, Reiser J. Altering the tropism of lentiviral vectors through pseudotyping. Curr Gene Ther 2005; 5: 387-398.
    • (2005) Curr Gene Ther , vol.5 , pp. 387-398
    • Cronin, J.1    Zhang, X.Y.2    Reiser, J.3
  • 34
    • 84988042486 scopus 로고    scopus 로고
    • Stereotaxic gene delivery in the rodent brain
    • Cetin A, Komai S, Eliava M, et al. Stereotaxic gene delivery in the rodent brain. Nat Protoc 2006; 1: 3166-3173.
    • (2006) Nat Protoc , vol.1 , pp. 3166-3173
    • Cetin, A.1    Komai, S.2    Eliava, M.3
  • 35
    • 0035207862 scopus 로고    scopus 로고
    • Neurogenesis in the subventricular zone and rostral migratory stream of the neonatal and adult primate forebrain
    • Pencea V, Bingaman KD, Freedman LJ, et al. Neurogenesis in the subventricular zone and rostral migratory stream of the neonatal and adult primate forebrain. Exp Neurol 2001; 172: 1-16.
    • (2001) Exp Neurol , vol.172 , pp. 1-16
    • Pencea, V.1    Bingaman, K.D.2    Freedman, L.J.3
  • 36
    • 0037079996 scopus 로고    scopus 로고
    • Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents
    • Gritti A, Bonfanti L, Doetsch F, et al. Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents. J Neurosci 2002; 22: 437-445.
    • (2002) J Neurosci , vol.22 , pp. 437-445
    • Gritti, A.1    Bonfanti, L.2    Doetsch, F.3
  • 37
    • 0031983640 scopus 로고    scopus 로고
    • Gene transfer and expression in oligodendrocytes under the control of myelin basic protein transcriptional control region mediated by adeno-associated virus
    • Chen H, McCarty DM, Bruce AT, et al. Gene transfer and expression in oligodendrocytes under the control of myelin basic protein transcriptional control region mediated by adeno-associated virus. Gene Ther 1998; 5: 50-58.
    • (1998) Gene Ther , vol.5 , pp. 50-58
    • Chen, H.1    McCarty, D.M.2    Bruce, A.T.3
  • 38
    • 0037110703 scopus 로고    scopus 로고
    • Expression of the green fluorescent protein in the oligodendrocyte lineage: a transgenic mouse for developmental and physiological studies
    • Yuan X, Chittajallu R, Belachew S, et al. Expression of the green fluorescent protein in the oligodendrocyte lineage: a transgenic mouse for developmental and physiological studies. J Neurosci Res 2002; 70: 529-545.
    • (2002) J Neurosci Res , vol.70 , pp. 529-545
    • Yuan, X.1    Chittajallu, R.2    Belachew, S.3
  • 39
    • 80052005086 scopus 로고    scopus 로고
    • Lentiviral-mediated gene transfer to the sheep brain: implications for gene therapy in Batten disease
    • Linterman KS, Palmer DN, Kay GW, et al. Lentiviral-mediated gene transfer to the sheep brain: implications for gene therapy in Batten disease. Hum Gene Ther 2011; 22: 1011-1020.
    • (2011) Hum Gene Ther , vol.22 , pp. 1011-1020
    • Linterman, K.S.1    Palmer, D.N.2    Kay, G.W.3
  • 40
    • 0037437148 scopus 로고    scopus 로고
    • Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    • Belachew S, Chittajallu R, Aguirre AA, et al. Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. J Cell Biol 2003; 161: 169-186.
    • (2003) J Cell Biol , vol.161 , pp. 169-186
    • Belachew, S.1    Chittajallu, R.2    Aguirre, A.A.3
  • 41
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch F, Caille I, Lim DA, et al. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 1999; 97: 703-716.
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3
  • 42
    • 0027405346 scopus 로고
    • Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain
    • Levison SW, Goldman JE. Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain. Neuron 1993; 10: 201-212.
    • (1993) Neuron , vol.10 , pp. 201-212
    • Levison, S.W.1    Goldman, J.E.2
  • 43
    • 0035499887 scopus 로고    scopus 로고
    • The development of neural stem cells
    • Temple S. The development of neural stem cells. Nature 2001; 414: 112-117.
    • (2001) Nature , vol.414 , pp. 112-117
    • Temple, S.1
  • 44
    • 2542456620 scopus 로고    scopus 로고
    • NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus
    • Aguirre AA, Chittajallu R, Belachew S, et al. NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus. J Cell Biol 2004; 165: 575-589.
    • (2004) J Cell Biol , vol.165 , pp. 575-589
    • Aguirre, A.A.1    Chittajallu, R.2    Belachew, S.3
  • 45
  • 46
    • 84875240244 scopus 로고    scopus 로고
    • Adeno-associated virus (AAV) gene therapy for neurological disease
    • Weinberg MS, Samulski RJ, McCown TJ. Adeno-associated virus (AAV) gene therapy for neurological disease. Neuropharmacology 2013; 69: 82-88.
    • (2013) Neuropharmacology , vol.69 , pp. 82-88
    • Weinberg, M.S.1    Samulski, R.J.2    McCown, T.J.3
  • 47
    • 77957328253 scopus 로고    scopus 로고
    • Molecular mechanisms of gap junction mutations in myelinating cells
    • Sargiannidou I, Markoullis K, Kleopa KA. Molecular mechanisms of gap junction mutations in myelinating cells. Histol Histopathol 2010; 25: 1191-1206.
    • (2010) Histol Histopathol , vol.25 , pp. 1191-1206
    • Sargiannidou, I.1    Markoullis, K.2    Kleopa, K.A.3
  • 48
    • 13844255953 scopus 로고    scopus 로고
    • Transgenic expression of human connexin32 in myelinating Schwann cells prevents demyelination in connexin32-null mice
    • Scherer SS, Xu YT, Messing A, et al. Transgenic expression of human connexin32 in myelinating Schwann cells prevents demyelination in connexin32-null mice. J Neurosci 2005; 25: 1550-1559.
    • (2005) J Neurosci , vol.25 , pp. 1550-1559
    • Scherer, S.S.1    Xu, Y.T.2    Messing, A.3
  • 49
    • 75649138386 scopus 로고    scopus 로고
    • Astroglial networks: a step further in neuroglial and gliovascular interactions
    • Giaume C, Koulakoff A, Roux L, et al. Astroglial networks: a step further in neuroglial and gliovascular interactions. Nat Rev Neurosci 2010; 11: 87-99.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 87-99
    • Giaume, C.1    Koulakoff, A.2    Roux, L.3
  • 50
    • 13844299470 scopus 로고    scopus 로고
    • The combined effects of inhibitory and electrical synapses in synchrony
    • Pfeuty B, Mato G, Golomb D, et al. The combined effects of inhibitory and electrical synapses in synchrony. Neural Comput 2005; 17: 633-670.
    • (2005) Neural Comput , vol.17 , pp. 633-670
    • Pfeuty, B.1    Mato, G.2    Golomb, D.3
  • 51
    • 0038383619 scopus 로고    scopus 로고
    • Connexins are critical for normal myelination in the CNS
    • Menichella DM, Goodenough DA, Sirkowski E, et al. Connexins are critical for normal myelination in the CNS. J Neurosci 2003; 23: 5963-5973.
    • (2003) J Neurosci , vol.23 , pp. 5963-5973
    • Menichella, D.M.1    Goodenough, D.A.2    Sirkowski, E.3
  • 52
    • 0038456539 scopus 로고    scopus 로고
    • Connexin 47 (Cx47)-deficient mice with enhanced green fluorescent protein reporter gene reveal predominant oligodendrocytic expression of Cx47 and display vacuolized myelin in the CNS
    • Odermatt B, Wellershaus K, Wallraff A, et al. Connexin 47 (Cx47)-deficient mice with enhanced green fluorescent protein reporter gene reveal predominant oligodendrocytic expression of Cx47 and display vacuolized myelin in the CNS. J Neurosci 2003; 23: 4549-4559.
    • (2003) J Neurosci , vol.23 , pp. 4549-4559
    • Odermatt, B.1    Wellershaus, K.2    Wallraff, A.3
  • 53
    • 33747039269 scopus 로고    scopus 로고
    • GJA12 mutations in children with recessive hypomyelinating leukoencephalopathy
    • Bugiani M, Al Shahwan S, Lamantea E, et al. GJA12 mutations in children with recessive hypomyelinating leukoencephalopathy. Neurology 2006; 67: 273-279.
    • (2006) Neurology , vol.67 , pp. 273-279
    • Bugiani, M.1    Al Shahwan, S.2    Lamantea, E.3
  • 54
    • 84871223039 scopus 로고    scopus 로고
    • High frequency of GJA12/GJC2 mutations in Turkish patients with Pelizaeus-Merzbacher disease
    • Bilir B, Yapici Z, Yalcinkaya C, et al. High frequency of GJA12/GJC2 mutations in Turkish patients with Pelizaeus-Merzbacher disease. Clin Genet 2013; 83: 66-72.
    • (2013) Clin Genet , vol.83 , pp. 66-72
    • Bilir, B.1    Yapici, Z.2    Yalcinkaya, C.3
  • 55
    • 26444604517 scopus 로고    scopus 로고
    • A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease
    • Martino S, Marconi P, Tancini B, et al. A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease. Hum Mol Genet 2005; 14: 2113-2123.
    • (2005) Hum Mol Genet , vol.14 , pp. 2113-2123
    • Martino, S.1    Marconi, P.2    Tancini, B.3
  • 56
    • 25144442267 scopus 로고    scopus 로고
    • Storage solutions: treating lysosomal disorders of the brain
    • Jeyakumar M, Dwek RA, Butters TD, et al. Storage solutions: treating lysosomal disorders of the brain. Nat Rev Neurosci 2005; 6: 713-725.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 713-725
    • Jeyakumar, M.1    Dwek, R.A.2    Butters, T.D.3
  • 57
    • 70349869180 scopus 로고    scopus 로고
    • Neural stem cell transplantation benefits a monogenic neurometabolic disorder during the symptomatic phase of disease
    • Jeyakumar M, Lee JP, Sibson NR, et al. Neural stem cell transplantation benefits a monogenic neurometabolic disorder during the symptomatic phase of disease. Stem Cells 2009; 27: 2362-2370.
    • (2009) Stem Cells , vol.27 , pp. 2362-2370
    • Jeyakumar, M.1    Lee, J.P.2    Sibson, N.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.