C-abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in alzheimer's disease

Molecular Cell

Volumn 56, Issue 1, 2014, Pages 163-173

  Gonzalez Zuñiga, Marcelo ^a,c   Contreras, Pablo S ^a   Estrada, Lisbell D ^a,c   Chamorro, David ^a   Villagra, Alejandro ^b   Zanlungo, Silvana ^a   Seto, Edward ^b   Alvarez, Alejandra R ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c UNIVERSIDAD BERNARDO O'HIGGINS   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; HISTONE DEACETYLASE 2; IMATINIB; HDAC2 PROTEIN, HUMAN; TYROSINE;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; EPIGENETIC REPRESSION; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC STABILITY; MOUSE; NERVE CELL; NONHUMAN; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HELA CELL LINE; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

MUS MUSCULUS;

ALZHEIMER DISEASE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HELA CELLS; HISTONE DEACETYLASE 2; HUMANS; NEURONS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-ABL; TYROSINE;

EID: 84916605627     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.08.013     Document Type: Article

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