메뉴 건너뛰기




Volumn 46, Issue 6, 2014, Pages 511-518

Effects of diabetes on oxidative and nitrosative stress in kidney mitochondria from aged rats

Author keywords

Aging; Diabetes; Glutathione; Kidney; Mitochondria; Nitric oxide; Oxidative stress

Indexed keywords

ACONITATE HYDRATASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; LIPID PEROXIDASE; NITRIC OXIDE; PROTEIN; STREPTOZOCIN; REACTIVE OXYGEN METABOLITE;

EID: 84916600708     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-014-9594-4     Document Type: Article
Times cited : (32)

References (52)
  • 1
    • 0019740345 scopus 로고
    • Assay of glutathione, glutathione disuylfide, and glutathione mixed disulfides in biological samples
    • COI: 1:CAS:528:DyaL38Xkt1Sjs7s%3D
    • Akerboom TP, Sies H (1981) Assay of glutathione, glutathione disuylfide, and glutathione mixed disulfides in biological samples. Methods Enzymol 77:373–382
    • (1981) Methods Enzymol , vol.77 , pp. 373-382
    • Akerboom, T.P.1    Sies, H.2
  • 2
    • 83055176412 scopus 로고    scopus 로고
    • Nitric oxide synthase derangements and hypertension in kidney disease
    • COI: 1:CAS:528:DC%2BC3MXhsFOgtrfL
    • Baylis C (2012) Nitric oxide synthase derangements and hypertension in kidney disease. Curr Opin Nephrol Hypertens 21(1):1–6
    • (2012) Curr Opin Nephrol Hypertens , vol.21 , Issue.1 , pp. 1-6
    • Baylis, C.1
  • 3
    • 0029682870 scopus 로고    scopus 로고
    • Oxidative damage and tyrosine nitration from peroxynitrite
    • COI: 1:CAS:528:DyaK28Xjs1Oktbk%3D
    • Beckman JS (1996) Oxidative damage and tyrosine nitration from peroxynitrite. Chem Res Toxicol 9(5):836–844
    • (1996) Chem Res Toxicol , vol.9 , Issue.5 , pp. 836-844
    • Beckman, J.S.1
  • 4
    • 0029012812 scopus 로고
    • Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system
    • COI: 1:CAS:528:DyaK2MXlvVagtrs%3D
    • Benzi G, Moretti A (1995) Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system. Free Radic Biol Med 19(1):77–101
    • (1995) Free Radic Biol Med , vol.19 , Issue.1 , pp. 77-101
    • Benzi, G.1    Moretti, A.2
  • 6
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buegue JA, Aust SD (1978) Microsomal lipid peroxidation. Methods Enzymol 52:302–320
    • (1978) Methods Enzymol , vol.52 , pp. 302-320
    • Buegue, J.A.1    Aust, S.D.2
  • 7
    • 0027409872 scopus 로고
    • Changes in uncoupling protein and GLUT4 glucose transporter expressions in interscapular brown adipose tissue of diabetic rats: relative roles of hyperglycaemia and hypoinsulinaemia
    • COI: 1:CAS:528:DyaK3sXitlWmsLs%3D
    • Burcelin R, Kande J, Ricquier D, Girard J (1993) Changes in uncoupling protein and GLUT4 glucose transporter expressions in interscapular brown adipose tissue of diabetic rats: relative roles of hyperglycaemia and hypoinsulinaemia. Biochem J 291(Pt 1):109–113
    • (1993) Biochem J , vol.291 , pp. 109-113
    • Burcelin, R.1    Kande, J.2    Ricquier, D.3    Girard, J.4
  • 8
    • 0033991466 scopus 로고    scopus 로고
    • Oxidative damage and protection of the RPE
    • COI: 1:CAS:528:DC%2BD3cXhtFarurs%3D
    • Cai J, Nelson KC, Wu M (2000) Oxidative damage and protection of the RPE. Prog Retin Eye Res 19(2):205–221
    • (2000) Prog Retin Eye Res , vol.19 , Issue.2 , pp. 205-221
    • Cai, J.1    Nelson, K.C.2    Wu, M.3
  • 9
    • 0022272480 scopus 로고
    • Glutathione reductase
    • COI: 1:CAS:528:DyaL28XkslCqsQ%3D%3D
    • Carlberg I, Mannervick B (1985) Glutathione reductase. Methods Enzymol 113:484–490
    • (1985) Methods Enzymol , vol.113 , pp. 484-490
    • Carlberg, I.1    Mannervick, B.2
  • 10
    • 79952562826 scopus 로고    scopus 로고
    • Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species
    • COI: 1:CAS:528:DC%2BC3MXjt1SqtL8%3D
    • Duan J, Kasper DL (2011) Oxidative depolymerization of polysaccharides by reactive oxygen/nitrogen species. Glycobiology 21(4):401–409
    • (2011) Glycobiology , vol.21 , Issue.4 , pp. 401-409
    • Duan, J.1    Kasper, D.L.2
  • 11
    • 0030697859 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in mitochondria
    • COI: 1:CAS:528:DyaK2sXnsVyjs74%3D
    • Ghafourifar P, Richter C (1997) Nitric oxide synthase activity in mitochondria. FEBS Lett 418(3):291–296
    • (1997) FEBS Lett , vol.418 , Issue.3 , pp. 291-296
    • Ghafourifar, P.1    Richter, C.2
  • 15
    • 0842328003 scopus 로고    scopus 로고
    • Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes
    • Green K, Brand MD, Murphy MP (2004) Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 53(Supl 1):110–118
    • (2004) Diabetes , vol.53 , Issue.Supl 1 , pp. 110-118
    • Green, K.1    Brand, M.D.2    Murphy, M.P.3
  • 16
    • 0014198972 scopus 로고
    • Purification and kinetic studies of beef liver cytoplasmic aconitase
    • COI: 1:CAS:528:DyaF2sXkslSksb4%3D
    • Henson CP, Cleland WW (1967) Purification and kinetic studies of beef liver cytoplasmic aconitase. J Biol Chem 242(17):3833–3838
    • (1967) J Biol Chem , vol.242 , Issue.17 , pp. 3833-3838
    • Henson, C.P.1    Cleland, W.W.2
  • 17
    • 77951818902 scopus 로고    scopus 로고
    • Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation
    • COI: 1:CAS:528:DC%2BC3cXms1amsrg%3D
    • Hou J, Chong ZZ, Shang YC, Maiese K (2010) Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation. Curr Neurovasc Res 7(2):95–112
    • (2010) Curr Neurovasc Res , vol.7 , Issue.2 , pp. 95-112
    • Hou, J.1    Chong, Z.Z.2    Shang, Y.C.3    Maiese, K.4
  • 18
    • 70449707755 scopus 로고    scopus 로고
    • Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1MXhtlyqtrzE
    • Kim MK, Ko SH, Baek KH, Ahn YB, Yoon KH, Kang MI, Lee KW, Song KH (2009) Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes. Korean J Intern Med 24(3):227–232
    • (2009) Korean J Intern Med , vol.24 , Issue.3 , pp. 227-232
    • Kim, M.K.1    Ko, S.H.2    Baek, K.H.3    Ahn, Y.B.4    Yoon, K.H.5    Kang, M.I.6    Lee, K.W.7    Song, K.H.8
  • 20
    • 0027365312 scopus 로고
    • Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
    • COI: 1:CAS:528:DyaK2cXitFenu78%3D
    • Ku HH, Brunk UT, Sohal RS (1993) Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Radic Biol Med 15(6):621–627
    • (1993) Free Radic Biol Med , vol.15 , Issue.6 , pp. 621-627
    • Ku, H.H.1    Brunk, U.T.2    Sohal, R.S.3
  • 21
    • 33750011601 scopus 로고    scopus 로고
    • Mitochondrial glutathione transport: physiological, pathological and toxicological implications
    • COI: 1:CAS:528:DC%2BD28XhtFSksbzF
    • Lash LH (2006) Mitochondrial glutathione transport: physiological, pathological and toxicological implications. Chem Biol Interact 163(1–2):54–67
    • (2006) Chem Biol Interact , vol.163 , Issue.1-2 , pp. 54-67
    • Lash, L.H.1
  • 22
    • 71849104860 scopus 로고
    • Protein measurement with the folin phenol reagent
    • COI: 1:CAS:528:DyaG38XhsVyrsw%3D%3D
    • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193(1):265–275
    • (1951) J Biol Chem , vol.193 , Issue.1 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3    Randall, R.J.4
  • 23
    • 84880495688 scopus 로고    scopus 로고
    • Methionine restriction affects oxidative stress and glutathione-related redox pathways in the rat
    • Maddineni S, Nichenametla S, Sinha R, Wilson RP, Richie JP Jr (2013) Methionine restriction affects oxidative stress and glutathione-related redox pathways in the rat. Exp Biol Med (Maywood) 238(4):392–399
    • (2013) Exp Biol Med (Maywood) , vol.238 , Issue.4 , pp. 392-399
    • Maddineni, S.1    Nichenametla, S.2    Sinha, R.3    Wilson, R.P.4    Richie, J.P.5
  • 24
    • 70349172654 scopus 로고    scopus 로고
    • Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: activation of polyol pathway and oxidative stress responsive signaling cascades
    • COI: 1:CAS:528:DC%2BD1MXhtFGksr7F
    • Manna P, Sinha M, Sil PC (2009) Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: activation of polyol pathway and oxidative stress responsive signaling cascades. Chem Biol Interact 181(3):297–308
    • (2009) Chem Biol Interact , vol.181 , Issue.3 , pp. 297-308
    • Manna, P.1    Sinha, M.2    Sil, P.C.3
  • 25
    • 80052681109 scopus 로고    scopus 로고
    • Peripheral vascular dysfunction in chronic kidney disease
    • 267257
    • Martens CR, Edwards DG (2011) Peripheral vascular dysfunction in chronic kidney disease. Cardiol Res Pract 2011:267257
    • (2011) Cardiol Res Pract , vol.2011
    • Martens, C.R.1    Edwards, D.G.2
  • 27
    • 4644327947 scopus 로고    scopus 로고
    • Highly selective and prolonged depletion of mitochondrial glutathione in astrocytes markedly increases sensitivity to peroxynitrite
    • COI: 1:CAS:528:DC%2BD2cXotVyis7s%3D
    • Muyderman H, Nilsson M, Sims NR (2004) Highly selective and prolonged depletion of mitochondrial glutathione in astrocytes markedly increases sensitivity to peroxynitrite. J Neurosci 24(37):8019–8028
    • (2004) J Neurosci , vol.24 , Issue.37 , pp. 8019-8028
    • Muyderman, H.1    Nilsson, M.2    Sims, N.R.3
  • 28
    • 0029564967 scopus 로고
    • Aged related changes in the lipofuscin accumulation of brain and heart
    • COI: 1:CAS:528:DyaK28XhsFGru7w%3D
    • Nakano M, Oenzil F, Mizuno T, Gotoh S (1995) Aged related changes in the lipofuscin accumulation of brain and heart. Int J Exp Clin Gerontol 41(2):69–79
    • (1995) Int J Exp Clin Gerontol , vol.41 , Issue.2 , pp. 69-79
    • Nakano, M.1    Oenzil, F.2    Mizuno, T.3    Gotoh, S.4
  • 30
    • 84857682442 scopus 로고    scopus 로고
    • Lipid peroxidative damage on cisplatin exposure and alterations in antioxidant defense system in rat kidneys: a possible protective effect of selenium
    • Ognjanovic BI, Djorjovic NZ, Matic MM, Obradovic JM, Mladenovic JM, Stajn AS, Saicic ZS (2012) Lipid peroxidative damage on cisplatin exposure and alterations in antioxidant defense system in rat kidneys: a possible protective effect of selenium. Int J Mol Sci 13(2):1790–1803
    • (2012) Int J Mol Sci , vol.13 , Issue.2 , pp. 1790-1803
    • Ognjanovic, B.I.1    Djorjovic, N.Z.2    Matic, M.M.3    Obradovic, J.M.4    Mladenovic, J.M.5    Stajn, A.S.6    Saicic, Z.S.7
  • 31
    • 33746540481 scopus 로고    scopus 로고
    • Decrease in tetrahydrobiopterin as a possible cause of nephropathy in type II diabetic rats
    • COI: 1:CAS:528:DC%2BD28XnsVChtrY%3D
    • Okumura M, Masada M, Yoshida Y, Hosoi M, Konishi Y, Morikawa T, Miura K (2006) Decrease in tetrahydrobiopterin as a possible cause of nephropathy in type II diabetic rats. Kidney Int 70(3):471–476
    • (2006) Kidney Int , vol.70 , Issue.3 , pp. 471-476
    • Okumura, M.1    Masada, M.2    Yoshida, Y.3    Hosoi, M.4    Konishi, Y.5    Morikawa, T.6    Miura, K.7
  • 32
    • 84878650897 scopus 로고    scopus 로고
    • Dietary avocado oil supplementation attenuates the alterations induced by type I diabetes and oxidative stress in electron transfer at the complex II-complex III segment of the electron transport chain in rat kidney mitochondria
    • COI: 1:CAS:528:DC%2BC3sXosFKrtbY%3D
    • Ortiz-Avila O, Sámano-García CA, Calderón-Cortés E, Pérez-Hernández IH, Mejía-Zepeda R, Rodríguez-Orozco AR, Saavedra-Molina A, Cortés-Rojo C (2013) Dietary avocado oil supplementation attenuates the alterations induced by type I diabetes and oxidative stress in electron transfer at the complex II-complex III segment of the electron transport chain in rat kidney mitochondria. J Bioenerg Bioembr 45(3):271–287
    • (2013) J Bioenerg Bioembr , vol.45 , Issue.3 , pp. 271-287
    • Ortiz-Avila, O.1    Sámano-García, C.A.2    Calderón-Cortés, E.3    Pérez-Hernández, I.H.4    Mejía-Zepeda, R.5    Rodríguez-Orozco, A.R.6    Saavedra-Molina, A.7    Cortés-Rojo, C.8
  • 33
    • 84864928432 scopus 로고    scopus 로고
    • Age-related changes in the rat brain mitochondrial antioxidative enzyme ratios: modulation by melatonin
    • Öztürk G, Akbulut KG, Güney S, Acuña-Castroviejo D (2012) Age-related changes in the rat brain mitochondrial antioxidative enzyme ratios: modulation by melatonin. Exp Gerontol 47(9):706–711
    • (2012) Exp Gerontol , vol.47 , Issue.9 , pp. 706-711
    • Öztürk, G.1    Akbulut, K.G.2    Güney, S.3    Acuña-Castroviejo, D.4
  • 34
    • 84926095457 scopus 로고    scopus 로고
    • Endothelin, nitric oxide, and reactive oxygen species in diabetic kidney disease
    • COI: 1:CAS:528:DC%2BC3MXhsFWjsr3P
    • Pollock JS, Pollock DM (2011) Endothelin, nitric oxide, and reactive oxygen species in diabetic kidney disease. Contrib Nephrol 172:149–159
    • (2011) Contrib Nephrol , vol.172 , pp. 149-159
    • Pollock, J.S.1    Pollock, D.M.2
  • 35
    • 35848956112 scopus 로고    scopus 로고
    • Diabetic nephropathy is associated with oxidative stress and decreased renal nitric oxide production
    • COI: 1:CAS:528:DC%2BD2sXhtlGgsbjN
    • Prabhakar S, Starnes J, Shi S, Lonis B, Tran R (2007) Diabetic nephropathy is associated with oxidative stress and decreased renal nitric oxide production. J Am Soc Nephrol 18(11):2945–2952
    • (2007) J Am Soc Nephrol , vol.18 , Issue.11 , pp. 2945-2952
    • Prabhakar, S.1    Starnes, J.2    Shi, S.3    Lonis, B.4    Tran, R.5
  • 36
    • 0036244508 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite interactions with mitochondria
    • COI: 1:CAS:528:DC%2BD38XksVajtrY%3D
    • Radi R, Cassina A, Hodara R (2002) Nitric oxide and peroxynitrite interactions with mitochondria. Biol Chem 383(3–4):401–409
    • (2002) Biol Chem , vol.383 , Issue.3-4 , pp. 401-409
    • Radi, R.1    Cassina, A.2    Hodara, R.3
  • 37
    • 0030808919 scopus 로고    scopus 로고
    • Effect of extra-and intra-mitochondrial calcium on citrulline synthesis in rat liver
    • COI: 1:CAS:528:DyaK2sXkvFKgs7c%3D
    • Saavedra-Molina A, Devlin TM (1997) Effect of extra-and intra-mitochondrial calcium on citrulline synthesis in rat liver. Amino Acids 12:293–298
    • (1997) Amino Acids , vol.12 , pp. 293-298
    • Saavedra-Molina, A.1    Devlin, T.M.2
  • 38
    • 77449156533 scopus 로고    scopus 로고
    • The mitochondrial free radical theory of aging: a critical review
    • COI: 1:CAS:528:DC%2BD1cXnsFWku78%3D
    • Sanz A, Rhoda SKA (2008) The mitochondrial free radical theory of aging: a critical review. Curr Aging Sci 1(1):10–21
    • (2008) Curr Aging Sci , vol.1 , Issue.1 , pp. 10-21
    • Sanz, A.1    Rhoda, S.K.A.2
  • 39
    • 20844432671 scopus 로고    scopus 로고
    • Pathogenetic mechanisms of diabetic nephropathy
    • COI: 1:CAS:528:DC%2BD2MXivVOmt70%3D
    • Schena FP, Gesualdo L (2005) Pathogenetic mechanisms of diabetic nephropathy. J Am Soc Nephrol 16(Suppl 1):S30–S33
    • (2005) J Am Soc Nephrol , vol.16 , pp. S30-S33
    • Schena, F.P.1    Gesualdo, L.2
  • 40
    • 0028085968 scopus 로고
    • Alterations in free radicals activity in aging drosophila
    • Shi I, Sawada M (1994) Alterations in free radicals activity in aging drosophila. Exp Gerontol 29(5):574–584
    • (1994) Exp Gerontol , vol.29 , Issue.5 , pp. 574-584
    • Shi, I.1    Sawada, M.2
  • 41
    • 0027457521 scopus 로고
    • The free radical hypothesis of aging: an appraisal of the current status
    • COI: 1:STN:280:DyaK3s3ksVeitQ%3D%3D
    • Sohal RS (1993) The free radical hypothesis of aging: an appraisal of the current status. Aging (Milano) 5(1):3–17
    • (1993) Aging (Milano) , vol.5 , Issue.1 , pp. 3-17
    • Sohal, R.S.1
  • 42
    • 0025640126 scopus 로고
    • Aged-related changes in antioxidants enzymes and pro-oxidant generation in tissues of the rat with special reference to parameters in two insect species
    • COI: 1:CAS:528:DyaK3MXltlamtLs%3D
    • Sohal RS, Arnold LA, Sohal BH (1990) Aged-related changes in antioxidants enzymes and pro-oxidant generation in tissues of the rat with special reference to parameters in two insect species. Free Radic Biol Med 9(6):495–500
    • (1990) Free Radic Biol Med , vol.9 , Issue.6 , pp. 495-500
    • Sohal, R.S.1    Arnold, L.A.2    Sohal, B.H.3
  • 43
    • 33847658682 scopus 로고    scopus 로고
    • Mitochondrial aconitase reaction with nitric oxide, S-nitrosoglutathione, and peroxynitrite: mechanisms and relative contributions to aconitase inactivation
    • Tórtora V, Quijano C, Freeman B, Radi R, Castro L (2007) Mitochondrial aconitase reaction with nitric oxide, S-nitrosoglutathione, and peroxynitrite: mechanisms and relative contributions to aconitase inactivation. Free Radic Biol Med 42(7):1075–1088
    • (2007) Free Radic Biol Med , vol.42 , Issue.7 , pp. 1075-1088
    • Tórtora, V.1    Quijano, C.2    Freeman, B.3    Radi, R.4    Castro, L.5
  • 45
    • 33749986298 scopus 로고    scopus 로고
    • Free radicals and antioxidants in normal physiological functions and human disease
    • COI: 1:CAS:528:DC%2BD28XhtVygt7%2FF
    • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39(1):44–84
    • (2007) Int J Biochem Cell Biol , vol.39 , Issue.1 , pp. 44-84
    • Valko, M.1    Leibfritz, D.2    Moncol, J.3    Cronin, M.T.4    Mazur, M.5    Telser, J.6
  • 47
    • 84877034863 scopus 로고    scopus 로고
    • Pancreatic islet cell autophagy during aging in rats
    • COI: 1:CAS:528:DC%2BC3sXotlOksLw%3D
    • Wang S, Sun QQ, Xiang B, Li XJ (2013) Pancreatic islet cell autophagy during aging in rats. Clin Invest Med 36(2):E72–E80
    • (2013) Clin Invest Med , vol.36 , Issue.2 , pp. E72-E80
    • Wang, S.1    Sun, Q.Q.2    Xiang, B.3    Li, X.J.4
  • 48
    • 0028109191 scopus 로고
    • Superoxide dismutase, aging and degenerative diseases
    • Warner HR (1994) Superoxide dismutase, aging and degenerative diseases. Free Radic Biol Med 7(3):249–258
    • (1994) Free Radic Biol Med , vol.7 , Issue.3 , pp. 249-258
    • Warner, H.R.1
  • 49
    • 0003725206 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications
    • Geneva, Switzerland:
    • WHO, World Health Organization (1999) Definition, diagnosis and classification of diabetes mellitus and its complications. Report of WHO Consultation, Geneva, Switzerland
    • (1999) Report of WHO Consultation
  • 50
    • 20044371040 scopus 로고    scopus 로고
    • In the aging housefly aconitase is the only citric acid cycle enzyme to decline significantly
    • COI: 1:CAS:528:DC%2BD2MXktlKkt7w%3D
    • Yarian CS, Sohal RS (2005) In the aging housefly aconitase is the only citric acid cycle enzyme to decline significantly. J Bioenerg Biomembr 37(2):91–96
    • (2005) J Bioenerg Biomembr , vol.37 , Issue.2 , pp. 91-96
    • Yarian, C.S.1    Sohal, R.S.2
  • 51
    • 15444370200 scopus 로고    scopus 로고
    • Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria
    • COI: 1:CAS:528:DC%2BD2MXisVCms70%3D
    • Yarian CS, Rebrin I, Sohal RS (2005) Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria. Biochem Biophys Res Commun 330(1):151–156
    • (2005) Biochem Biophys Res Commun , vol.330 , Issue.1 , pp. 151-156
    • Yarian, C.S.1    Rebrin, I.2    Sohal, R.S.3
  • 52
    • 28244454785 scopus 로고    scopus 로고
    • Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice
    • COI: 1:CAS:528:DC%2BD2MXht1Ols7jL
    • Yarian CS, Toroser D, Sohal RS (2006) Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice. Mech Ageing Dev 127(1):79–84
    • (2006) Mech Ageing Dev , vol.127 , Issue.1 , pp. 79-84
    • Yarian, C.S.1    Toroser, D.2    Sohal, R.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.