메뉴 건너뛰기




Volumn 28, Issue 1, 2015, Pages 1-9

Caveats of mesenchymal stem cell therapy in solid organ transplantation

Author keywords

mesenchymal stem cells; risks; solid organ transplantation; stromal cells

Indexed keywords

IMMUNOSUPPRESSIVE AGENT;

EID: 84916599780     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12415     Document Type: Review
Times cited : (43)

References (72)
  • 1
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF,. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143.
    • (1999) Science , vol.284 , pp. 143
    • Pittenger, M.F.1
  • 2
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D, Schwarz EJ, Prockop DJ, Black IB,. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000; 61: 364.
    • (2000) J Neurosci Res , vol.61 , pp. 364
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 3
    • 0028788268 scopus 로고
    • Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine
    • Wakitani S, Saito T, Caplan AI,. Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve 1995; 18: 1417.
    • (1995) Muscle Nerve , vol.18 , pp. 1417
    • Wakitani, S.1    Saito, T.2    Caplan, A.I.3
  • 4
    • 10944256054 scopus 로고    scopus 로고
    • In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions
    • Anjos-Afonso F, Siapati EK, Bonnet D,. In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions. J Cell Sci 2004; 117: 5655.
    • (2004) J Cell Sci , vol.117 , pp. 5655
    • Anjos-Afonso, F.1    Siapati, E.K.2    Bonnet, D.3
  • 5
    • 0036050976 scopus 로고    scopus 로고
    • Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cells from a related donor with one fully mismatched human leucocyte antigen haplotype
    • Lee ST, Jang JH, Cheong J-W, et al,. Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cells from a related donor with one fully mismatched human leucocyte antigen haplotype. Br J Haematol 2002; 118: 1128.
    • (2002) Br J Haematol , vol.118 , pp. 1128
    • Lee, S.T.1    Jang, J.H.2    Cheong, J.-W.3
  • 6
    • 35348831024 scopus 로고    scopus 로고
    • Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis
    • Wu Y, Chen L, Scott PG, Tredget EE,. Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells 2007; 25: 2648.
    • (2007) Stem Cells , vol.25 , pp. 2648
    • Wu, Y.1    Chen, L.2    Scott, P.G.3    Tredget, E.E.4
  • 7
    • 21244470714 scopus 로고    scopus 로고
    • Immunogenicity of adult mesenchymal stem cells: Lessons from the fetal allograft
    • Barry FP, Murphy JM, English K, Mahon BP,. Immunogenicity of adult mesenchymal stem cells: lessons from the fetal allograft. Stem Cell Dev 2005; 14: 252.
    • (2005) Stem Cell Dev , vol.14 , pp. 252
    • Barry, F.P.1    Murphy, J.M.2    English, K.3    Mahon, B.P.4
  • 8
    • 84876510229 scopus 로고    scopus 로고
    • Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: Results of a phase i study
    • Reinders ME, de Fijter JW, Roelofs H, et al,. Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study. Stem Cells Transl Med 2013; 2: 107.
    • (2013) Stem Cells Transl Med , vol.2 , pp. 107
    • Reinders, M.E.1    De Fijter, J.W.2    Roelofs, H.3
  • 9
    • 34548044258 scopus 로고    scopus 로고
    • Potential risks of bone marrow cell transplantation into infarcted hearts
    • Breitbach M, Bostani T, Roell W, et al,. Potential risks of bone marrow cell transplantation into infarcted hearts. Blood 2007; 110: 1362.
    • (2007) Blood , vol.110 , pp. 1362
    • Breitbach, M.1    Bostani, T.2    Roell, W.3
  • 10
    • 84882450956 scopus 로고    scopus 로고
    • Mesenchymal stromal cells and kidney transplantation: Pretransplant infusion protects from graft dysfunction while fostering immunoregulation
    • Perico N, Casiraghi F, Gotti E, et al,. Mesenchymal stromal cells and kidney transplantation: pretransplant infusion protects from graft dysfunction while fostering immunoregulation. Transpl Int 2013; 26: 867.
    • (2013) Transpl Int , vol.26 , pp. 867
    • Perico, N.1    Casiraghi, F.2    Gotti, E.3
  • 11
    • 33745433769 scopus 로고    scopus 로고
    • Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation
    • Miura M, Miura Y, Padilla-Nash HM, et al,. Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation. Stem Cells 2006; 24: 1095.
    • (2006) Stem Cells , vol.24 , pp. 1095
    • Miura, M.1    Miura, Y.2    Padilla-Nash, H.M.3
  • 12
    • 56049100237 scopus 로고    scopus 로고
    • Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate
    • Popp FC, Eggenhofer E, Renner P, et al,. Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate. Transpl Immunol 2008; 20: 55.
    • (2008) Transpl Immunol , vol.20 , pp. 55
    • Popp, F.C.1    Eggenhofer, E.2    Renner, P.3
  • 13
    • 67650932291 scopus 로고    scopus 로고
    • Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance
    • Ge W, Jiang J, Baroja ML, et al,. Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance. Am J Transplant 2009; 9: 1760.
    • (2009) Am J Transplant , vol.9 , pp. 1760
    • Ge, W.1    Jiang, J.2    Baroja, M.L.3
  • 14
    • 0038376000 scopus 로고    scopus 로고
    • Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration
    • Rafii S, Lyden D,. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med 2003; 9: 702.
    • (2003) Nat Med , vol.9 , pp. 702
    • Rafii, S.1    Lyden, D.2
  • 15
    • 33845341472 scopus 로고    scopus 로고
    • Spontaneous transformation of cultured mouse bone marrow-derived stromal cells
    • Zhou YF, Bosch-Marce M, Okuyama H, et al,. Spontaneous transformation of cultured mouse bone marrow-derived stromal cells. Cancer Res 2006; 66: 10849.
    • (2006) Cancer Res , vol.66 , pp. 10849
    • Zhou, Y.F.1    Bosch-Marce, M.2    Okuyama, H.3
  • 16
    • 58949095822 scopus 로고    scopus 로고
    • Development of sarcomas in mice implanted with mesenchymal stem cells seeded onto bioscaffolds
    • Tasso R, Augello A, Carida M, et al,. Development of sarcomas in mice implanted with mesenchymal stem cells seeded onto bioscaffolds. Carcinogenesis 2009; 30: 150.
    • (2009) Carcinogenesis , vol.30 , pp. 150
    • Tasso, R.1    Augello, A.2    Carida, M.3
  • 17
    • 34547567884 scopus 로고    scopus 로고
    • The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles
    • Hall B, Andreeff M, Marini F,. The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles. Handb Exp Pharmacol 2007; 180: 263.
    • (2007) Handb Exp Pharmacol , vol.180 , pp. 263
    • Hall, B.1    Andreeff, M.2    Marini, F.3
  • 18
    • 33846483151 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: Impact on in vivo tumor growth
    • Ramasamy R, Lam EW, Soeiro I, Tisato V, Bonnet D, Dazzi F,. Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth. Leukemia 2007; 21: 304.
    • (2007) Leukemia , vol.21 , pp. 304
    • Ramasamy, R.1    Lam, E.W.2    Soeiro, I.3    Tisato, V.4    Bonnet, D.5    Dazzi, F.6
  • 19
    • 84884820906 scopus 로고    scopus 로고
    • Impact of cyclosporine versus tacrolimus on the incidence of de novo malignancy following liver transplantation: A single center experience with 609 patients
    • Wimmer CD, Angele MK, Schwarz B, et al,. Impact of cyclosporine versus tacrolimus on the incidence of de novo malignancy following liver transplantation: a single center experience with 609 patients. Transpl Int 2013; 26: 999.
    • (2013) Transpl Int , vol.26 , pp. 999
    • Wimmer, C.D.1    Angele, M.K.2    Schwarz, B.3
  • 20
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • Dominici M, Le Blanc K, Mueller I, et al,. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8: 315.
    • (2006) Cytotherapy , vol.8 , pp. 315
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3
  • 21
    • 77954439580 scopus 로고    scopus 로고
    • GMP-manufactured density gradient media for optimized mesenchymal stromal/stem cell isolation and expansion
    • Grisendi G, Anneren C, Cafarelli L, et al,. GMP-manufactured density gradient media for optimized mesenchymal stromal/stem cell isolation and expansion. Cytotherapy 2010; 12: 466.
    • (2010) Cytotherapy , vol.12 , pp. 466
    • Grisendi, G.1    Anneren, C.2    Cafarelli, L.3
  • 23
    • 84884972512 scopus 로고    scopus 로고
    • Culture expansion induces non-tumorigenic aneuploidy in adipose tissue-derived mesenchymal stromal cells
    • Roemeling-van Rhijn M, de Klein A, Douben H, et al,. Culture expansion induces non-tumorigenic aneuploidy in adipose tissue-derived mesenchymal stromal cells. Cytotherapy 2013; 15: 1352.
    • (2013) Cytotherapy , vol.15 , pp. 1352
    • Roemeling-Van Rhijn, M.1    De Klein, A.2    Douben, H.3
  • 24
    • 33846910469 scopus 로고    scopus 로고
    • Sarcoma derived from cultured mesenchymal stem cells
    • Tolar J, Nauta AJ, Osborn MJ, et al,. Sarcoma derived from cultured mesenchymal stem cells. Stem Cells 2007; 25: 371.
    • (2007) Stem Cells , vol.25 , pp. 371
    • Tolar, J.1    Nauta, A.J.2    Osborn, M.J.3
  • 25
    • 34547115678 scopus 로고    scopus 로고
    • Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung
    • Aguilar S, Nye E, Chan J, et al,. Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung. Stem Cells 2007; 25: 1586.
    • (2007) Stem Cells , vol.25 , pp. 1586
    • Aguilar, S.1    Nye, E.2    Chan, J.3
  • 26
    • 17144363265 scopus 로고    scopus 로고
    • Spontaneous human adult stem cell transformation
    • Rubio D, Garcia-Castro J, Martin MC, et al,. Spontaneous human adult stem cell transformation. Cancer Res 2005; 65: 3035.
    • (2005) Cancer Res , vol.65 , pp. 3035
    • Rubio, D.1    Garcia-Castro, J.2    Martin, M.C.3
  • 27
    • 42349104345 scopus 로고    scopus 로고
    • High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence
    • Meza-Zepeda LA, Noer A, Dahl JA, Micci F, Myklebost O, Collas P,. High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence. J Cell Mol Med 2008; 12: 553.
    • (2008) J Cell Mol Med , vol.12 , pp. 553
    • Meza-Zepeda, L.A.1    Noer, A.2    Dahl, J.A.3    Micci, F.4    Myklebost, O.5    Collas, P.6
  • 28
    • 61449505236 scopus 로고    scopus 로고
    • Genetic and epigenetic instability of human bone marrow mesenchymal stem cells expanded in autologous serum or fetal bovine serum
    • Dahl JA, Duggal S, Coulston N, et al,. Genetic and epigenetic instability of human bone marrow mesenchymal stem cells expanded in autologous serum or fetal bovine serum. Int J Dev Biol 2008; 52: 1033.
    • (2008) Int J Dev Biol , vol.52 , pp. 1033
    • Dahl, J.A.1    Duggal, S.2    Coulston, N.3
  • 30
    • 84873713507 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cell therapy and risk of malignancies
    • Casiraghi F, Remuzzi G, Abbate M, Perico N,. Multipotent mesenchymal stromal cell therapy and risk of malignancies. Stem Cell Rev 2013; 9: 65.
    • (2013) Stem Cell Rev , vol.9 , pp. 65
    • Casiraghi, F.1    Remuzzi, G.2    Abbate, M.3    Perico, N.4
  • 31
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, et al,. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007; 449: 557.
    • (2007) Nature , vol.449 , pp. 557
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3
  • 32
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F, Plence P, Bony C, et al,. Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood 2003; 102: 3837.
    • (2003) Blood , vol.102 , pp. 3837
    • Djouad, F.1    Plence, P.2    Bony, C.3
  • 33
    • 40749112327 scopus 로고    scopus 로고
    • The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: Outcome of a pilot clinical study
    • Ning H, Yang F, Jiang M, et al,. The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study. Leukemia 2008; 22: 593.
    • (2008) Leukemia , vol.22 , pp. 593
    • Ning, H.1    Yang, F.2    Jiang, M.3
  • 34
    • 77952584405 scopus 로고    scopus 로고
    • Cotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning
    • Baron F, Lechanteur C, Willems E, et al,. Cotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning. Biol Blood Marrow Transplant 2010; 16: 838.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 838
    • Baron, F.1    Lechanteur, C.2    Willems, E.3
  • 35
    • 80052592013 scopus 로고    scopus 로고
    • Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids
    • Roodhart JM, Daenen LG, Stigter EC, et al,. Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids. Cancer Cell 2011; 20: 370.
    • (2011) Cancer Cell , vol.20 , pp. 370
    • Roodhart, J.M.1    Daenen, L.G.2    Stigter, E.C.3
  • 36
    • 0038281370 scopus 로고    scopus 로고
    • Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates
    • Devine SM, Cobbs C, Jennings M, Bartholomew A, Hoffman R,. Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates. Blood 2003; 101: 2999.
    • (2003) Blood , vol.101 , pp. 2999
    • Devine, S.M.1    Cobbs, C.2    Jennings, M.3    Bartholomew, A.4    Hoffman, R.5
  • 37
    • 0033678140 scopus 로고    scopus 로고
    • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
    • Liechty KW, MacKenzie TC, Shaaban AF, et al,. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 2000; 6: 1282.
    • (2000) Nat Med , vol.6 , pp. 1282
    • Liechty, K.W.1    MacKenzie, T.C.2    Shaaban, A.F.3
  • 39
    • 0037380791 scopus 로고    scopus 로고
    • Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ
    • Helczynska K, Kronblad A, Jogi A, et al,. Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ. Cancer Res 2003; 63: 1441.
    • (2003) Cancer Res , vol.63 , pp. 1441
    • Helczynska, K.1    Kronblad, A.2    Jogi, A.3
  • 40
    • 0037076385 scopus 로고    scopus 로고
    • Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype
    • Jogi A, Ora I, Nilsson H, et al,. Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype. Proc Natl Acad Sci USA 2002; 99: 7021.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7021
    • Jogi, A.1    Ora, I.2    Nilsson, H.3
  • 42
    • 18144384703 scopus 로고    scopus 로고
    • Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling
    • Nobta M, Tsukazaki T, Shibata Y, et al,. Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling. J Biol Chem 2005; 280: 15842.
    • (2005) J Biol Chem , vol.280 , pp. 15842
    • Nobta, M.1    Tsukazaki, T.2    Shibata, Y.3
  • 43
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki J, Smith AG,. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000; 24: 372.
    • (2000) Nat Genet , vol.24 , pp. 372
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 44
    • 79956010254 scopus 로고    scopus 로고
    • JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation
    • Pietras A, von Stedingk K, Lindgren D, Pahlman S, Axelson H,. JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation. Mol Cancer Res 2011; 9: 626.
    • (2011) Mol Cancer Res , vol.9 , pp. 626
    • Pietras, A.1    Von Stedingk, K.2    Lindgren, D.3    Pahlman, S.4    Axelson, H.5
  • 45
    • 79953196468 scopus 로고    scopus 로고
    • Nuclear orphan receptor TLX induces Oct-3/4 for the survival and maintenance of adult hippocampal progenitors upon hypoxia
    • Chavali PL, Saini RK, Matsumoto Y, Agren H, Funa K,. Nuclear orphan receptor TLX induces Oct-3/4 for the survival and maintenance of adult hippocampal progenitors upon hypoxia. J Biol Chem 2011; 286: 9393.
    • (2011) J Biol Chem , vol.286 , pp. 9393
    • Chavali, P.L.1    Saini, R.K.2    Matsumoto, Y.3    Agren, H.4    Funa, K.5
  • 46
    • 84855808363 scopus 로고    scopus 로고
    • Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells
    • Sheehy EJ, Buckley CT, Kelly DJ,. Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells. Biochem Biophys Res Commun 2012; 417: 305.
    • (2012) Biochem Biophys Res Commun , vol.417 , pp. 305
    • Sheehy, E.J.1    Buckley, C.T.2    Kelly, D.J.3
  • 47
    • 77049122836 scopus 로고    scopus 로고
    • Hypoxic preconditioning of human mesenchymal stem cells overcomes hypoxia-induced inhibition of osteogenic differentiation
    • Volkmer E, Kallukalam BC, Maertz J, et al,. Hypoxic preconditioning of human mesenchymal stem cells overcomes hypoxia-induced inhibition of osteogenic differentiation. Tissue Eng Part A 2010; 16: 153.
    • (2010) Tissue Eng Part A , vol.16 , pp. 153
    • Volkmer, E.1    Kallukalam, B.C.2    Maertz, J.3
  • 48
    • 0014854456 scopus 로고
    • The effect of prior transfusion on marrow grafts between histocompatible canine siblings
    • Storb R, Epstein RB, Rudolph RH, Thomas ED,. The effect of prior transfusion on marrow grafts between histocompatible canine siblings. J Immunol 1970; 105: 627.
    • (1970) J Immunol , vol.105 , pp. 627
    • Storb, R.1    Epstein, R.B.2    Rudolph, R.H.3    Thomas, E.D.4
  • 49
    • 0017358359 scopus 로고
    • Marrow transplantation for treatment of aplastic anemia. An analysis of factors associated with graft rejection
    • Storb R, Prentice RL, Thomas ED,. Marrow transplantation for treatment of aplastic anemia. An analysis of factors associated with graft rejection. N Engl J Med 1977; 296: 61.
    • (1977) N Engl J Med , vol.296 , pp. 61
    • Storb, R.1    Prentice, R.L.2    Thomas, E.D.3
  • 50
    • 79955037007 scopus 로고    scopus 로고
    • Expression of blood group genes by mesenchymal stem cells
    • Schafer R, Schnaidt M, Klaffschenkel RA, et al,. Expression of blood group genes by mesenchymal stem cells. Br J Haematol 2011; 153: 520.
    • (2011) Br J Haematol , vol.153 , pp. 520
    • Schafer, R.1    Schnaidt, M.2    Klaffschenkel, R.A.3
  • 51
    • 84898007335 scopus 로고    scopus 로고
    • Do ABO blood group antigens hamper the therapeutic efficacy of mesenchymal stromal cells?
    • Moll G, Hult A, von Bahr L, et al,. Do ABO blood group antigens hamper the therapeutic efficacy of mesenchymal stromal cells? PLoS ONE 2014; 9: e85040.
    • (2014) PLoS ONE , vol.9 , pp. e85040
    • Moll, G.1    Hult, A.2    Von Bahr, L.3
  • 52
    • 36348946918 scopus 로고    scopus 로고
    • No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients
    • Sundin M, Ringden O, Sundberg B, Nava S, Gotherstrom C, Le Blanc K,. No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients. Haematologica 2007; 92: 1208.
    • (2007) Haematologica , vol.92 , pp. 1208
    • Sundin, M.1    Ringden, O.2    Sundberg, B.3    Nava, S.4    Gotherstrom, C.5    Le Blanc, K.6
  • 53
    • 0037173116 scopus 로고    scopus 로고
    • Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
    • Horwitz EM, Gordon PL, Koo WK, et al,. Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proc Natl Acad Sci USA 2002; 99: 8932.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8932
    • Horwitz, E.M.1    Gordon, P.L.2    Koo, W.K.3
  • 54
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • Eliopoulos N, Stagg J, Lejeune L, Pommey S, Galipeau J,. Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood 2005; 106: 4057.
    • (2005) Blood , vol.106 , pp. 4057
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3    Pommey, S.4    Galipeau, J.5
  • 55
    • 33746514768 scopus 로고    scopus 로고
    • Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting
    • Nauta AJ, Westerhuis G, Kruisselbrink AB, Lurvink EG, Willemze R, Fibbe WE,. Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006; 108: 2114.
    • (2006) Blood , vol.108 , pp. 2114
    • Nauta, A.J.1    Westerhuis, G.2    Kruisselbrink, A.B.3    Lurvink, E.G.4    Willemze, R.5    Fibbe, W.E.6
  • 56
    • 78649374199 scopus 로고    scopus 로고
    • Immunological aspects of allogeneic mesenchymal stem cell therapies
    • Griffin MD, Ritter T, Mahon BP,. Immunological aspects of allogeneic mesenchymal stem cell therapies. Hum Gene Ther 2010; 21: 1641.
    • (2010) Hum Gene Ther , vol.21 , pp. 1641
    • Griffin, M.D.1    Ritter, T.2    Mahon, B.P.3
  • 58
    • 38049181475 scopus 로고    scopus 로고
    • Immunogenicity of umbilical cord tissue derived cells
    • Cho PS, Messina DJ, Hirsh EL, et al,. Immunogenicity of umbilical cord tissue derived cells. Blood 2008; 111: 430.
    • (2008) Blood , vol.111 , pp. 430
    • Cho, P.S.1    Messina, D.J.2    Hirsh, E.L.3
  • 59
    • 79960655506 scopus 로고    scopus 로고
    • Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation-a phase i study (MISOT-I)
    • Popp FC, Fillenberg B, Eggenhofer E, et al,. Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation-a phase I study (MISOT-I). J Transl Med 2011; 9: 124.
    • (2011) J Transl Med , vol.9 , pp. 124
    • Popp, F.C.1    Fillenberg, B.2    Eggenhofer, E.3
  • 60
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells
    • Glennie S, Soeiro I, Dyson PJ, Lam EW, Dazzi F,. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood 2005; 105: 2821.
    • (2005) Blood , vol.105 , pp. 2821
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3    Lam, E.W.4    Dazzi, F.5
  • 61
    • 0033828190 scopus 로고    scopus 로고
    • Evidence for migration of donor bone marrow stromal cells into recipient thymus after bone marrow transplantation plus bone grafts
    • Li Y, Hisha H, Inaba M, et al,. Evidence for migration of donor bone marrow stromal cells into recipient thymus after bone marrow transplantation plus bone grafts. Exp Hematol 2000; 28: 950.
    • (2000) Exp Hematol , vol.28 , pp. 950
    • Li, Y.1    Hisha, H.2    Inaba, M.3
  • 62
    • 0141484485 scopus 로고    scopus 로고
    • HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells
    • Le Blanc K, Tammik C, Rosendahl K, Zetterberg E, Ringden O,. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 2003; 31: 890.
    • (2003) Exp Hematol , vol.31 , pp. 890
    • Le Blanc, K.1    Tammik, C.2    Rosendahl, K.3    Zetterberg, E.4    Ringden, O.5
  • 63
    • 84916641663 scopus 로고    scopus 로고
    • Human allogeneic bone marrow and adipose tissue derived mesenchymal stromal cells induce CD8+ cytotoxic T cell reactivity
    • Roemeling-van Rhijn M, Reinders ME, Franquesa M, et al,. Human allogeneic bone marrow and adipose tissue derived mesenchymal stromal cells induce CD8+ cytotoxic T cell reactivity. J Stem Cell Res Ther 2013; 3: 004.
    • (2013) J Stem Cell Res Ther , vol.3 , pp. 004
    • Roemeling-Van Rhijn, M.1    Reinders, M.E.2    Franquesa, M.3
  • 64
    • 62449124523 scopus 로고    scopus 로고
    • Glycomics of bone marrow-derived mesenchymal stem cells can be used to evaluate their cellular differentiation stage
    • Heiskanen A, Hirvonen T, Salo H, et al,. Glycomics of bone marrow-derived mesenchymal stem cells can be used to evaluate their cellular differentiation stage. Glycoconj J 2009; 26: 367.
    • (2009) Glycoconj J , vol.26 , pp. 367
    • Heiskanen, A.1    Hirvonen, T.2    Salo, H.3
  • 65
    • 33644522374 scopus 로고    scopus 로고
    • The immunogenicity and immunomodulatory function of osteogenic cells differentiated from mesenchymal stem cells
    • Liu H, Kemeny DM, Heng BC, Ouyang HW, Melendez AJ, Cao T,. The immunogenicity and immunomodulatory function of osteogenic cells differentiated from mesenchymal stem cells. J Immunol 2006; 176: 2864.
    • (2006) J Immunol , vol.176 , pp. 2864
    • Liu, H.1    Kemeny, D.M.2    Heng, B.C.3    Ouyang, H.W.4    Melendez, A.J.5    Cao, T.6
  • 66
    • 84863338204 scopus 로고    scopus 로고
    • Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: A randomized controlled trial
    • Tan J, Wu W, Xu X, et al,. Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial. JAMA 2012; 307: 1169.
    • (2012) JAMA , vol.307 , pp. 1169
    • Tan, J.1    Wu, W.2    Xu, X.3
  • 67
    • 67650145156 scopus 로고    scopus 로고
    • Results of a pilot study on the use of third-party donor mesenchymal stromal cells in cord blood transplantation in adults
    • Gonzalo-Daganzo R, Regidor C, Martin-Donaire T, et al,. Results of a pilot study on the use of third-party donor mesenchymal stromal cells in cord blood transplantation in adults. Cytotherapy 2009; 11: 278.
    • (2009) Cytotherapy , vol.11 , pp. 278
    • Gonzalo-Daganzo, R.1    Regidor, C.2    Martin-Donaire, T.3
  • 68
    • 20244389227 scopus 로고    scopus 로고
    • Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients
    • Lazarus HM, Koc ON, Devine SM, et al,. Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients. Biol Blood Marrow Transplant 2005; 11: 389.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 389
    • Lazarus, H.M.1    Koc, O.N.2    Devine, S.M.3
  • 69
    • 84905819811 scopus 로고    scopus 로고
    • Impact of cotransplantation of mesenchymal stem cells on lung function after unrelated allogeneic hematopoietic stem cell transplantation following non-myeloablative conditioning
    • Moermans C, Lechanteur C, Baudoux E, et al,. Impact of cotransplantation of mesenchymal stem cells on lung function after unrelated allogeneic hematopoietic stem cell transplantation following non-myeloablative conditioning. Transplantation 2014; 98: 348.
    • (2014) Transplantation , vol.98 , pp. 348
    • Moermans, C.1    Lechanteur, C.2    Baudoux, E.3
  • 70
    • 84901627546 scopus 로고    scopus 로고
    • Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy
    • Han Z, Jing Y, Xia Y, et al,. Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy. Cell Biosci 2014; 4: 22.
    • (2014) Cell Biosci , vol.4 , pp. 22
    • Han, Z.1    Jing, Y.2    Xia, Y.3
  • 71
    • 84902106468 scopus 로고    scopus 로고
    • Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-kappaB mediates chemoresistance
    • Jacamo R, Chen Y, Wang Z, et al,. Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-kappaB mediates chemoresistance. Blood 2014; 123: 2691.
    • (2014) Blood , vol.123 , pp. 2691
    • Jacamo, R.1    Chen, Y.2    Wang, Z.3
  • 72
    • 84872164299 scopus 로고    scopus 로고
    • Detrimental effects of rat mesenchymal stromal cell pre-treatment in a model of acute kidney rejection
    • Seifert M, Stolk M, Polenz D, Volk HD,. Detrimental effects of rat mesenchymal stromal cell pre-treatment in a model of acute kidney rejection. Front Immunol 2012; 3: 202.
    • (2012) Front Immunol , vol.3 , pp. 202
    • Seifert, M.1    Stolk, M.2    Polenz, D.3    Volk, H.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.