Culture Expansion Induces Non-Tumorigenic Aneuploidy In Adipose Tissue-Derived Mesenchymal Stromal Cells

Cytotherapy

Volumn 15, Issue 11, 2013, Pages 1352-1361

  Roemeling van Rhijn, Marieke ^a   de Klein, Annelies ^a   Douben, Hannie ^a   Pan, Qiuwei ^a   van der Laan, Luc J W ^a   Ijzermans, Jan N M ^a   Betjes, Michiel G H ^a   Baan, Carla C ^a   Weimar, Willem ^a   Hoogduijn, Martin J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Adipose tissue; Aneuploidy; Clinical application; Mesenchymal stromal cell; Senescence; Transformation

Indexed keywords

ADIPOSE TISSUE; ADIPOSE TISSUE DERIVED MESENCHYMAL STROMA CELL; ADULT; AGED; ANEUPLOIDY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CELL CLONING; CELL CULTURE; CELL EXPANSION; CELL ISOLATION; CELL TRANSFORMATION; CONTROLLED STUDY; DEGENERATIVE DISEASE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DOSAGE; GENE MUTATION; GENETIC SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPATHOLOGY; MALE; MESENCHYMAL STROMA CELL; NONHUMAN; NONOBESE DIABETIC MOUSE; PLASTICITY; PRIORITY JOURNAL; SCID MOUSE; SENESCENCE;

ADIPOSE TISSUE; ANEUPLOIDY; CLINICAL APPLICATION; MESENCHYMAL STROMAL CELL; SENESCENCE; TRANSFORMATION;

ADIPOSE TISSUE; ADULT; AGED; ANEUPLOIDY; ANIMALS; CELL AGING; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELL- AND TISSUE-BASED THERAPY; CELLS, CULTURED; CLONE CELLS; FEMALE; GENOMIC INSTABILITY; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, SCID; MIDDLE AGED;

EID: 84884972512     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2013.07.004     Document Type: Article

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