p38 MAP kinase mediates transforming-growth factor-β1-induced upregulation of matrix metalloproteinase-9 but not -2 in human brain pericytes

Brain Research

Volumn 1593, Issue , 2014, Pages 1-8

  Takahashi, Yoko ^a,b   Maki, Takakuni ^b   Liang, Anna C ^b   Itoh, Kanako ^b   Lok, Josephine ^b   Osumi, Noriko ^a   Arai, Ken ^b  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

MMP 9; Neurovascular unit; p38 MAP kinase; Pericyte

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; CENTRAL NERVOUS SYSTEM AGENTS; ENZYME INHIBITOR; GELATINASE A; GELATINASE B; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE P38; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; PYRIDINE DERIVATIVE; RECOMBINANT PROTEIN; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANTAGONISTS AND INHIBITORS; BRAIN; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; HUMAN; METABOLISM; PERICYTE; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; UPREGULATION;

BENZAMIDES; BRAIN; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM AGENTS; DIOXOLES; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERICYTES; PHOSPHORYLATION; PYRIDINES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84916226547     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.10.029     Document Type: Article

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