How much oxycodone is needed for adequate analgesia after breast cancer surgery: Effect of the OPRM1 118A>G polymorphism

Journal of Pain

Volumn 15, Issue 12, 2014, Pages 1248-1256

  Cajanus, Kristiina ^a   Kaunisto, Mari A ^b,c   Tallgren, Minna ^a   Jokela, Ritva ^a   Kalso, Eija ^a,d  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Analgesics; experimental pain; mu polymorphism; opioid; oxycodone pain; postoperative receptors; single nucleotide

Indexed keywords

ADENINE; GUANINE; OXYCODONE; MU OPIATE RECEPTOR; NARCOTIC ANALGESIC AGENT; OPRM1 PROTEIN, HUMAN; PHARMACOLOGICAL BIOMARKER;

ADULT; ANALGESIA; ARTICLE; BREAST CANCER; CANCER SURGERY; COLD SENSITIVITY; DRUG USE; FEMALE; GENE OPRM1; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HEAT SENSITIVITY; HUMAN; MAJOR CLINICAL STUDY; MARKER GENE; NOCICEPTION; PATIENT CONTROLLED ANALGESIA; PHENOTYPE; POSTOPERATIVE PAIN; BREAST NEOPLASMS; GENETIC ASSOCIATION; GENETICS; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PATHOPHYSIOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; BIOMARKERS, PHARMACOLOGICAL; BREAST NEOPLASMS; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; LINEAR MODELS; MIDDLE AGED; OXYCODONE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, OPIOID, MU;

EID: 84916215984     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2014.09.002     Document Type: Article

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