cAMP regulates expression of the cyclic nucleotide transporter MRP4 (ABCC4) through the EPAC pathway

Pharmacogenetics and Genomics

Volumn 24, Issue 10, 2014, Pages 522-526

  Bröderdorf, Susanne ^a   Zang, Sebastian ^a   Schaletzki, Yvonne ^a   Grube, Markus ^a   Kroemer, Heyo K ^a,b   Jedlitschky, Gabriele ^a  

^a Medical University of Greifswald   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

Cyclic AMP; Exchange protein activated by cyclic AMP; Mitogen activated protein kinases; Multidrug resistance protein 4 (MRP4 ABCC4); Reporter gene assay; Transcriptional regulation

Indexed keywords

ANTIPORTER; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; EXCHANGE PROTEIN ACTIVATED BY CYCLIC AMP; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 4; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ABCC4 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN;

ARTICLE; CELL TYPE; CONTROLLED STUDY; HELA CELL LINE; HUMAN; HUMAN CELL; LONG TERM CARE; MYELOID LEUKEMIA; PROMOTER REGION; REPORTER GENE; SMOOTH MUSCLE FIBER; UPREGULATION; ANALOGS AND DERIVATIVES; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUSCLE CELL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE;

CELLS, CULTURED; CYCLIC AMP; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUSCLE CELLS; MUSCLE, SMOOTH; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84916212304     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0000000000000084     Document Type: Article

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