메뉴 건너뛰기




Volumn 11, Issue 2, 2015, Pages 1366-1371

Chloroquine inhibits MGC803 gastric cancer cell migration via the Toll-like receptor 9/nuclear factor kappa B signaling pathway

Author keywords

Cell migration; Chloroquine; Gastric cancer; Nuclear factor KB p65; Toll like receptor 9

Indexed keywords

ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT; CHLOROQUINE; CYCLOOXYGENASE 2; GELATINASE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRILYSIN; MESSENGER RNA; TLR9 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR RELA;

EID: 84916197147     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2839     Document Type: Article
Times cited : (25)

References (31)
  • 2
    • 84902149178 scopus 로고    scopus 로고
    • Prognostic significance of metastatic lymph node ratio in patients with gastric cancer: An evaluation in North-East of Iran
    • Taghizadeh-Kermani A, Yahouiyan SZ, AliAkbarian M and Seilanian Toussi M: Prognostic significance of metastatic lymph node ratio in patients with gastric cancer: an evaluation in North-East of Iran. Iran J Cancer Prev 7: 73-79, 2014.
    • (2014) Iran J Cancer Prev , vol.7 , pp. 73-79
    • Taghizadeh-Kermani, A.1    Yahouiyan, S.Z.2    Aliakbarian, M.3    Seilanian Toussi, M.4
  • 3
    • 84909640386 scopus 로고    scopus 로고
    • Microarray analysis in gastric cancer: A review
    • D'Angelo G, Di Rienzo T and Ojetti V: Microarray analysis in gastric cancer: A review. World J Gastroenterol 20: 11972-11976, 2014.
    • (2014) World J Gastroenterol , vol.20 , pp. 11972-11976
    • D'Angelo, G.1    Di Rienzo, T.2    Ojetti, V.3
  • 4
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A and Ulevitch RJ: Toll-like receptors in the induction of the innate immune response. Nature 406: 782-787, 2000.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 5
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K and Akira S: Toll-like receptors in innate immunity. Int Immunol 17: 1-14, 2005.
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 6
    • 84865571191 scopus 로고    scopus 로고
    • TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification
    • Oldenburg M, Krger A, Ferstl R, Kaufmann A, Nees G, Sigmund A, et al: TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. Science 337: 1111-1115, 2012.
    • (2012) Science , vol.337 , pp. 1111-1115
    • Oldenburg, M.1    Krger, A.2    Ferstl, R.3    Kaufmann, A.4    Nees, G.5    Sigmund, A.6
  • 8
    • 77957269986 scopus 로고    scopus 로고
    • Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors
    • Berger R, Fiegl H, Goebel G, Obexer P, Ausserlechner M, Doppler wW, et al: Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors. Cancer Sci 101: 1059-1066, 2010.
    • (2010) Cancer Sci , vol.101 , pp. 1059-1066
    • Berger, R.1    Fiegl, H.2    Goebel, G.3    Obexer, P.4    Ausserlechner, M.5    Doppler, W.6
  • 9
    • 2542510727 scopus 로고    scopus 로고
    • Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection
    • Schmausser B, Andrulis M, Endrich S, Lee SK, Josenhans C, Mller-Hermelink HK, et al: Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection. Clin Exp Immunol 136: 521-526, 2004.
    • (2004) Clin Exp Immunol , vol.136 , pp. 521-526
    • Schmausser, B.1    Andrulis, M.2    Endrich, S.3    Lee, S.K.4    Josenhans, C.5    Mller-Hermelink, H.K.6
  • 11
    • 84878923605 scopus 로고    scopus 로고
    • TLR9 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
    • Wang X, Xue L, Yang Y, Xu L and Zhang G: TLR9 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. PLoS One 8: e65731, 2013.
    • (2013) PLoS One , vol.8 , pp. e65731
    • Wang, X.1    Xue, L.2    Yang, Y.3    Xu, L.4    Zhang, G.5
  • 12
    • 2942679083 scopus 로고    scopus 로고
    • The immunobiology of the TLR9 subfamily
    • Wagner H: The immunobiology of the TLR9 subfamily. Trends Immunol 25: 381-386, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 381-386
    • Wagner, H.1
  • 13
    • 84887557344 scopus 로고    scopus 로고
    • Identification of the IGF1/PI3K/NFkB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer
    • Koti M, Gooding RJ, Nuin P, Haslehurst A, Crane C, Weberpals J, et al: Identification of the IGF1/PI3K/NFkB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer. BMC Cancer 13: 549, 2013.
    • (2013) BMC Cancer , vol.13 , pp. 549
    • Koti, M.1    Gooding, R.J.2    Nuin, P.3    Haslehurst, A.4    Crane, C.5    Weberpals, J.6
  • 14
    • 84894482142 scopus 로고    scopus 로고
    • Autophagy facilitates TLR4-and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination
    • Zhan Z, Xie X, Cao H, Zhou X, Zhang XD, Fan H, et al: Autophagy facilitates TLR4-and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy 10: 257-268, 2013.
    • (2013) Autophagy , vol.10 , pp. 257-268
    • Zhan, Z.1    Xie, X.2    Cao, H.3    Zhou, X.4    Zhang, X.D.5    Fan, H.6
  • 15
    • 84916207595 scopus 로고    scopus 로고
    • Correlations of TLR9 to clinicopathologic features of gastric cancer
    • Ma YJ, Cui L, Zhang YL and Li XP: Correlations of TLR9 to clinicopathologic features of gastric cancer. J Ningxia Med Univ 34: 126-128, 2012.
    • (2012) J Ningxia Med Univ , vol.34 , pp. 126-128
    • Ma, Y.J.1    Cui, L.2    Zhang, Y.L.3    Li, X.P.4
  • 17
    • 84907499482 scopus 로고    scopus 로고
    • Surgical outcomes and prognostic factors of T4 gastric cancer patients without distant metastasis
    • Li MZ, Deng L, Wang JJ, Xiao LB, Wu WH, Yang SB and Li WF: Surgical outcomes and prognostic factors of T4 gastric cancer patients without distant metastasis. PLoS One 9:e107061, 2014.
    • (2014) PLoS One , vol.9 , pp. e107061
    • Li, M.Z.1    Deng, L.2    Wang, J.J.3    Xiao, L.B.4    Wu, W.H.5    Yang, S.B.6    Li, W.F.7
  • 18
    • 84905695208 scopus 로고    scopus 로고
    • Toll-like receptors and cancer: MYD88 mutation and inflammation
    • Wang JQ, Jeelall YS, Ferguson LL and Horikawa K: Toll-like receptors and cancer: MYD88 mutation and inflammation. Front Immunol 5: 367-377, 2014.
    • (2014) Front Immunol , vol.5 , pp. 367-377
    • Wang, J.Q.1    Jeelall, Y.S.2    Ferguson, L.L.3    Horikawa, K.4
  • 21
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM: CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 20: 709-760, 2002.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 23
    • 79251614052 scopus 로고    scopus 로고
    • NF-?B JNK and TLR signaling pathways in hepatocarcinogenesis
    • Maeda S: NF-?B, JNK, and TLR signaling pathways in hepatocarcinogenesis. Gastroenterol Res Pract: 367694, 2010.
    • (2010) Gastroenterol Res Pract , vol.36 , pp. 7694
    • Maeda, S.1
  • 24
    • 0036494318 scopus 로고    scopus 로고
    • Cyclooxygenase-2 activity altered the cell-surface ca-rbohydrate antigens on colon cancer cells and enhanced liver metastasis
    • Kakiuchi Y, Tsuji S, Tsujii M, Murata H, Kawai N and Yasumaru M, et al: Cyclooxygenase-2 activity altered the cell-surface ca-rbohydrate antigens on colon cancer cells and enhanced liver metastasis. Cancer Res 62: 1567-1572, 2002.
    • (2002) Cancer Res , vol.62 , pp. 1567-1572
    • Kakiuchi, Y.1    Tsuji, S.2    Tsujii, M.3    Murata, H.4    Kawai, N.5    Yasumaru, M.6
  • 25
    • 37849032618 scopus 로고    scopus 로고
    • Cancers take their Toll-The function and regulation of Toll-like receptors in cancer cells
    • Chen R, Alvero AB, Silasi DA, Steffensen KD and Mor G: Cancers take their Toll-the function and regulation of Toll-like receptors in cancer cells. Oncogene 27: 225-233, 2008.
    • (2008) Oncogene , vol.27 , pp. 225-233
    • Chen, R.1    Alvero, A.B.2    Silasi, D.A.3    Steffensen, K.D.4    Mor, G.5
  • 26
    • 63449131596 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 involvement in breast cancer progression: A mini-review
    • Jezierska A and Motyl T: Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review. Med Sci Monit 15: RA32-RA40, 2009.
    • (2009) Med Sci Monit , vol.15 , pp. RA32-RA40
    • Jezierska, A.1    Motyl, T.2
  • 27
    • 79954994442 scopus 로고    scopus 로고
    • Extracellular heat shock protein (Hsp)70 and Hsp90? Assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion
    • Sims JD, McCready J and Jay DG: Extracellular heat shock protein (Hsp)70 and Hsp90? assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion. PLoS One 6: e18848, 2011.
    • (2011) PLoS One , vol.6 , pp. e18848
    • Sims, J.D.1    McCready, J.2    Jay, D.G.3
  • 28
    • 70350746167 scopus 로고    scopus 로고
    • CD44v6 MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer
    • Okayama H, Kumamoto K, Saitou K, Hayase S, Kofunato Y, Sato Y, et al: CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer. Oncol Rep 22: 745-755, 2009.
    • (2009) Oncol Rep , vol.22 , pp. 745-755
    • Okayama, H.1    Kumamoto, K.2    Saitou, K.3    Hayase, S.4    Kofunato, Y.5    Sato, Y.6
  • 29
    • 77954424331 scopus 로고    scopus 로고
    • Elevated serum matrix metalloproteinase-3 and-7 in H. Pylori-related gastric cancer can be biomarkers correlating with a poor survival
    • Yeh YC, Sheu BS, Cheng HC, Wang YL, Yang HB and Wu JJ: Elevated serum matrix metalloproteinase-3 and-7 in H. pylori-related gastric cancer can be biomarkers correlating with a poor survival. Dig Dis Sci 55: 1649-1657, 2010.
    • (2010) Dig Dis Sci , vol.55 , pp. 1649-1657
    • Yeh, Y.C.1    Sheu, B.S.2    Cheng, H.C.3    Wang, Y.L.4    Yang, H.B.5    Wu, J.J.6
  • 30
    • 84899088228 scopus 로고    scopus 로고
    • Cyclooxygenase 2 genotypes influence prostate cancer susceptibility in Japanese men
    • Sugie S, Tsukino H, Mukai S, Akioka T, Shibata N, Nagano M and Kamoto T: Cyclooxygenase 2 genotypes influence prostate cancer susceptibility in Japanese men. Tumour Biol 35: 2717-2721, 2014.
    • (2014) Tumour Biol , vol.35 , pp. 2717-2721
    • Sugie, S.1    Tsukino, H.2    Mukai, S.3    Akioka, T.4    Shibata, N.5    Nagano, M.6    Kamoto, T.7
  • 31
    • 84886998357 scopus 로고    scopus 로고
    • Expression and significance of cyclooxygenase-2 mRNA in benign and malignant ascites
    • Lu J, Li XF, Kong LX, Ma L, Liao SH and Jiang CY: Expression and significance of cyclooxygenase-2 mRNA in benign and malignant ascites. World J Gastroenterol 19: 6883-6887, 2013.
    • (2013) World J Gastroenterol , vol.19 , pp. 6883-6887
    • Lu, J.1    Li, X.F.2    Kong, L.X.3    Ma, L.4    Liao, S.H.5    Jiang, C.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.