Original mechanisms of antipsychotic action by the indole alkaloid alstonine (Picralima nitida)

Phytomedicine

Volumn 22, Issue 1, 2015, Pages 52-55

  Linck, Viviane M ^a   Ganzella, Marcelo ^a   Herrmann, Ana P ^a   Okunji, Christopher O ^b   Souza, Diogo O ^a   Antonelli, Marta C ^c   Elisabetsky, Elaine ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b International Centre for Ethnomedicine and Drug Development (InterCEDD)   (Nigeria)

^c Facultad de Medicina   (Argentina)

Author keywords

Alstonine; Antipsychotics; D2 dopamine receptor; Dopamine uptake; Indole alkaloid; Picralima nitida; Schizophrenia

Indexed keywords

ALSTONINE; CLOZAPINE; DOPAMINE; DOPAMINE 2 RECEPTOR; EMONAPRIDE; INDOLE ALKALOID; NEUROLEPTIC AGENT; UNCLASSIFIED DRUG; RAUWOLFIA ALKALOID; SERPENTINE (ALKALOID);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BRAIN REGION; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINE UPTAKE; DOPAMINERGIC TRANSMISSION; DRUG BINDING; DRUG MECHANISM; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PICRALIMA NITIDA; PUTAMEN; SYNAPTOSOME; ANIMAL; APOCYNACEAE; CHEMISTRY; DRUG EFFECTS; FRUIT; METABOLISM;

PICRALIMA NITIDA;

ANIMALS; ANTIPSYCHOTIC AGENTS; APOCYNACEAE; AUTORADIOGRAPHY; DOPAMINE; FRUIT; MALE; MICE; NUCLEUS ACCUMBENS; PUTAMEN; RECEPTORS, DOPAMINE D2; SECOLOGANIN TRYPTAMINE ALKALOIDS; SYNAPTOSOMES;

EID: 84915822617     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.10.010     Document Type: Article

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