메뉴 건너뛰기




Volumn 24, Issue 4, 2011, Pages 631-642

Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching

Author keywords

LEF1; Melanoma; MITF; TCF4; WNT5A

Indexed keywords

BETA CATENIN; LYMPHOID ENHANCER FACTOR 1; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR TCF4; UNCLASSIFIED DRUG; WNT PROTEIN; WNT5A PROTEIN;

EID: 80051875971     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2011.00871.x     Document Type: Article
Times cited : (79)

References (63)
  • 1
    • 0032563564 scopus 로고    scopus 로고
    • Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein
    • Adams, C.L., Chen, Y.T., Smith, S.J., and Nelson, W.J. (1998). Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein. J. Cell Biol. 142, 1105-1119.
    • (1998) J. Cell Biol. , vol.142 , pp. 1105-1119
    • Adams, C.L.1    Chen, Y.T.2    Smith, S.J.3    Nelson, W.J.4
  • 3
    • 33845355511 scopus 로고    scopus 로고
    • Diversity of LEF/TCF action in development and disease
    • Arce, L., Yokoyama, N.N., and Waterman, M.L. (2006). Diversity of LEF/TCF action in development and disease. Oncogene 25, 7492-7504.
    • (2006) Oncogene , vol.25 , pp. 7492-7504
    • Arce, L.1    Yokoyama, N.N.2    Waterman, M.L.3
  • 4
    • 67649859499 scopus 로고    scopus 로고
    • Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression
    • Arce, L., Pate, K.T., and Waterman, M.L. (2009). Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression. BMC Cancer 9, 159.
    • (2009) BMC Cancer , vol.9 , pp. 159
    • Arce, L.1    Pate, K.T.2    Waterman, M.L.3
  • 5
    • 29344459785 scopus 로고    scopus 로고
    • Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma
    • Bachmann, I.M., Straume, O., Puntervoll, H.E., Kalvenes, M.B., and Akslen, L.A. (2005). Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clin. Cancer Res. 11, 8606-8614.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 8606-8614
    • Bachmann, I.M.1    Straume, O.2    Puntervoll, H.E.3    Kalvenes, M.B.4    Akslen, L.A.5
  • 6
    • 41049114747 scopus 로고    scopus 로고
    • How to make a melanoma: what do we know of the primary clonal events?
    • Bennett, D.C. (2008). How to make a melanoma: what do we know of the primary clonal events? Pigment Cell Melanoma Res. 21, 27-38.
    • (2008) Pigment Cell Melanoma Res. , vol.21 , pp. 27-38
    • Bennett, D.C.1
  • 7
    • 0034601455 scopus 로고    scopus 로고
    • Molecular classification of cutaneous malignant melanoma by gene expression profiling
    • Bittner, M., Meltzer, P., Chen, Y. et al. (2000). Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature 406, 536-540.
    • (2000) Nature , vol.406 , pp. 536-540
    • Bittner, M.1    Meltzer, P.2    Chen, Y.3
  • 8
    • 0036124896 scopus 로고    scopus 로고
    • TCF: lady Justice casting the final verdict on the outcome of Wnt signalling
    • Brantjes, H., Barker, N., Van Es, J., and Clevers, H. (2002). TCF: lady Justice casting the final verdict on the outcome of Wnt signalling. Biol. Chem. 383, 255-261.
    • (2002) Biol. Chem. , vol.383 , pp. 255-261
    • Brantjes, H.1    Barker, N.2    Van Es, J.3    Clevers, H.4
  • 9
    • 0035110161 scopus 로고    scopus 로고
    • Analysis of microphthalmia transcription factor expression in normal tissues and tumors, and comparison of its expression with S-100 protein, gp100, and tyrosinase in desmoplastic malignant melanoma
    • Busam, K.J., Iversen, K., Coplan, K.C., and Jungbluth, A.A. (2001). Analysis of microphthalmia transcription factor expression in normal tissues and tumors, and comparison of its expression with S-100 protein, gp100, and tyrosinase in desmoplastic malignant melanoma. Am. J. Surg. Pathol. 25, 197-204.
    • (2001) Am. J. Surg. Pathol. , vol.25 , pp. 197-204
    • Busam, K.J.1    Iversen, K.2    Coplan, K.C.3    Jungbluth, A.A.4
  • 13
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers, H. (2006). Wnt/beta-catenin signaling in development and disease. Cell 127, 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 14
    • 58149100136 scopus 로고    scopus 로고
    • Novel regulation of vascular endothelial growth factor-A (VEGF-A) by transforming growth factor (beta)1: requirement for Smads, (beta)-CATENIN, AND GSK3(beta)
    • Clifford, R.L., Deacon, K., and Knox, A.J. (2008). Novel regulation of vascular endothelial growth factor-A (VEGF-A) by transforming growth factor (beta)1: requirement for Smads, (beta)-CATENIN, AND GSK3(beta). J. Biol. Chem. 283, 35337-35353.
    • (2008) J. Biol. Chem. , vol.283 , pp. 35337-35353
    • Clifford, R.L.1    Deacon, K.2    Knox, A.J.3
  • 17
    • 36249026528 scopus 로고    scopus 로고
    • Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development
    • Delmas, V., Beermann, F., Martinozzi, S. et al. (2007). Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev. 21, 2923-2935.
    • (2007) Genes Dev. , vol.21 , pp. 2923-2935
    • Delmas, V.1    Beermann, F.2    Martinozzi, S.3
  • 18
    • 0036229264 scopus 로고    scopus 로고
    • Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations
    • Demunter, A., Libbrecht, L., Degreef, H., De Wolf-Peeters, C., and Van Den Oord, J.J. (2002). Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations. Mod. Pathol. 15, 454-461.
    • (2002) Mod. Pathol. , vol.15 , pp. 454-461
    • Demunter, A.1    Libbrecht, L.2    Degreef, H.3    De Wolf-Peeters, C.4    Van Den Oord, J.J.5
  • 19
    • 34447131518 scopus 로고    scopus 로고
    • The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition
    • Dissanayake, S.K., Wade, M., Johnson, C.E. et al. (2007). The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. J. Biol. Chem. 282, 17259-17271.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17259-17271
    • Dissanayake, S.K.1    Wade, M.2    Johnson, C.E.3
  • 20
    • 57749098673 scopus 로고    scopus 로고
    • Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation
    • Dissanayake, S.K., Olkhanud, P.B., O'connell, M.P. et al. (2008). Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res. 68, 10205-10214.
    • (2008) Cancer Res. , vol.68 , pp. 10205-10214
    • Dissanayake, S.K.1    Olkhanud, P.B.2    O'connell, M.P.3
  • 21
    • 0032569852 scopus 로고    scopus 로고
    • Control of neural crest cell fate by the Wnt signalling pathway
    • Dorsky, R.I., Moon, R.T., and Raible, D.W. (1998). Control of neural crest cell fate by the Wnt signalling pathway. Nature 396, 370-373.
    • (1998) Nature , vol.396 , pp. 370-373
    • Dorsky, R.I.1    Moon, R.T.2    Raible, D.W.3
  • 22
    • 77954656425 scopus 로고    scopus 로고
    • The immunohistochemistry of invasive and proliferative phenotype switching in melanoma: a case report
    • Eichhoff, O.M., Zipser, M.C., Xu, M., Weeraratna, A.T., Mihic, D., Dummer, R., and Hoek, K.S. (2010). The immunohistochemistry of invasive and proliferative phenotype switching in melanoma: a case report. Melanoma Res. 20, 349-355.
    • (2010) Melanoma Res. , vol.20 , pp. 349-355
    • Eichhoff, O.M.1    Zipser, M.C.2    Xu, M.3    Weeraratna, A.T.4    Mihic, D.5    Dummer, R.6    Hoek, K.S.7
  • 23
    • 0031660839 scopus 로고    scopus 로고
    • Higher frequency of selective losses of HLA-A and -B allospecificities in metastasis than in primary melanoma lesions
    • Geertsen, R.C., Hofbauer, G.F., Yue, F.Y., Manolio, S., Burg, G., and Dummer, R. (1998). Higher frequency of selective losses of HLA-A and -B allospecificities in metastasis than in primary melanoma lesions. J. Invest. Dermatol. 111, 497-502.
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 497-502
    • Geertsen, R.C.1    Hofbauer, G.F.2    Yue, F.Y.3    Manolio, S.4    Burg, G.5    Dummer, R.6
  • 25
    • 70350728812 scopus 로고    scopus 로고
    • Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis
    • Haughian, J.M., Reno, E.M., Thorne, A.M., and Bradford, A.P. (2009). Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis. Int. J. Cancer 125, 2556-2564.
    • (2009) Int. J. Cancer , vol.125 , pp. 2556-2564
    • Haughian, J.M.1    Reno, E.M.2    Thorne, A.M.3    Bradford, A.P.4
  • 26
    • 0037423192 scopus 로고    scopus 로고
    • Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4
    • Hecht, A., and Stemmler, M.P. (2003). Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4. J. Biol. Chem. 278, 3776-3785.
    • (2003) J. Biol. Chem. , vol.278 , pp. 3776-3785
    • Hecht, A.1    Stemmler, M.P.2
  • 27
    • 34147093740 scopus 로고    scopus 로고
    • Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling
    • Herzig, M., Savarese, F., Novatchkova, M., Semb, H., and Christofori, G. (2007). Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling. Oncogene 26, 2290-2298.
    • (2007) Oncogene , vol.26 , pp. 2290-2298
    • Herzig, M.1    Savarese, F.2    Novatchkova, M.3    Semb, H.4    Christofori, G.5
  • 28
    • 78049237405 scopus 로고    scopus 로고
    • Cancer stem cells versus phenotype-switching in melanoma
    • Hoek, K.S., and Goding, C.R. (2010). Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell Melanoma Res. 23, 746-759.
    • (2010) Pigment Cell Melanoma Res. , vol.23 , pp. 746-759
    • Hoek, K.S.1    Goding, C.R.2
  • 29
    • 33745753404 scopus 로고    scopus 로고
    • Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature
    • Hoek, K.S., Schlegel, N.C., Brafford, P. et al. (2006). Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Res. 19, 290-302.
    • (2006) Pigment Cell Res. , vol.19 , pp. 290-302
    • Hoek, K.S.1    Schlegel, N.C.2    Brafford, P.3
  • 31
    • 56249119207 scopus 로고    scopus 로고
    • Novel MITF targets identified using a two-step DNA microarray strategy
    • Hoek, K.S., Schlegel, N.C., Eichhoff, O.M. et al. (2008b). Novel MITF targets identified using a two-step DNA microarray strategy. Pigment Cell Melanoma Res. 21, 665-676.
    • (2008) Pigment Cell Melanoma Res. , vol.21 , pp. 665-676
    • Hoek, K.S.1    Schlegel, N.C.2    Eichhoff, O.M.3
  • 32
    • 77954874401 scopus 로고    scopus 로고
    • SK3 signalling in neural development
    • Hur, E.M., and Zhou, F.Q. (2010). SK3 signalling in neural development. Nat. Rev. Neurosci. 11, 539-551.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 539-551
    • Hur, E.M.1    Zhou, F.Q.2
  • 33
    • 77954049394 scopus 로고    scopus 로고
    • A gene expression signature of invasive potential in metastatic melanoma cells
    • Jeffs, A.R., Glover, A.C., Slobbe, L.J. et al. (2009). A gene expression signature of invasive potential in metastatic melanoma cells. PLoS ONE 4, e8461.
    • (2009) PLoS ONE , vol.4
    • Jeffs, A.R.1    Glover, A.C.2    Slobbe, L.J.3
  • 34
    • 67649515610 scopus 로고    scopus 로고
    • Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades
    • Katoh, M. (2009). Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades. Int. J. Mol. Med. 23, 763-769.
    • (2009) Int. J. Mol. Med. , vol.23 , pp. 763-769
    • Katoh, M.1
  • 35
    • 47149097853 scopus 로고    scopus 로고
    • Epigenetic gene silencing in the Wnt pathway in breast cancer
    • Klarmann, G.J., Decker, A., and Farrar, W.L. (2008). Epigenetic gene silencing in the Wnt pathway in breast cancer. Epigenetics 3, 59-63.
    • (2008) Epigenetics , vol.3 , pp. 59-63
    • Klarmann, G.J.1    Decker, A.2    Farrar, W.L.3
  • 36
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus, A., and Birchmeier, W. (2008). Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer 8, 387-398.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 38
    • 78549285669 scopus 로고    scopus 로고
    • LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer
    • Kriegl, L., Horst, D., Reiche, J.A., Engel, J., Kirchner, T., and Jung, A. (2010). LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer. J. Transl. Med. 8, 123.
    • (2010) J. Transl. Med. , vol.8 , pp. 123
    • Kriegl, L.1    Horst, D.2    Reiche, J.A.3    Engel, J.4    Kirchner, T.5    Jung, A.6
  • 39
    • 9144247129 scopus 로고    scopus 로고
    • Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma
    • Kuphal, S., Poser, I., Jobin, C., Hellerbrand, C., and Bosserhoff, A.K. (2004). Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma. Oncogene 23, 8509-8519.
    • (2004) Oncogene , vol.23 , pp. 8509-8519
    • Kuphal, S.1    Poser, I.2    Jobin, C.3    Hellerbrand, C.4    Bosserhoff, A.K.5
  • 40
    • 32944460267 scopus 로고    scopus 로고
    • The WNT/Beta-catenin pathway in melanoma
    • Larue, L., and Delmas, V. (2006). The WNT/Beta-catenin pathway in melanoma. Front. Biosci. 11, 733-742.
    • (2006) Front. Biosci. , vol.11 , pp. 733-742
    • Larue, L.1    Delmas, V.2
  • 41
    • 0038578680 scopus 로고    scopus 로고
    • Beta-catenin in the melanocyte lineage
    • Larue, L., Kumasaka, M., and Goding, C.R. (2003). Beta-catenin in the melanocyte lineage. Pigment Cell Res. 16, 312-317.
    • (2003) Pigment Cell Res. , vol.16 , pp. 312-317
    • Larue, L.1    Kumasaka, M.2    Goding, C.R.3
  • 42
    • 33747882661 scopus 로고    scopus 로고
    • MITF: master regulator of melanocyte development and melanoma oncogene
    • Levy, C., Khaled, M., and Fisher, D.E. (2006). MITF: master regulator of melanocyte development and melanoma oncogene. Trends Mol. Med. 12, 406-414.
    • (2006) Trends Mol. Med. , vol.12 , pp. 406-414
    • Levy, C.1    Khaled, M.2    Fisher, D.E.3
  • 43
    • 12144254034 scopus 로고    scopus 로고
    • MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A
    • Loercher, A.E., Tank, E.M., Delston, R.B., and Harbour, J.W. (2005). MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A. J. Cell Biol. 168, 35-40.
    • (2005) J. Cell Biol. , vol.168 , pp. 35-40
    • Loercher, A.E.1    Tank, E.M.2    Delston, R.B.3    Harbour, J.W.4
  • 45
    • 34447641262 scopus 로고    scopus 로고
    • The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia
    • Mikesch, J.H., Steffen, B., Berdel, W.E., Serve, H., and Muller-Tidow, C. (2007). The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia. Leukemia 21, 1638-1647.
    • (2007) Leukemia , vol.21 , pp. 1638-1647
    • Mikesch, J.H.1    Steffen, B.2    Berdel, W.E.3    Serve, H.4    Muller-Tidow, C.5
  • 46
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson, W.J., and Nusse, R. (2004). Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303, 1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 47
    • 0032729458 scopus 로고    scopus 로고
    • Signaling through beta-catenin and Lef/Tcf
    • Novak, A., and Dedhar, S. (1999). Signaling through beta-catenin and Lef/Tcf. Cell. Mol. Life Sci. 56, 523-537.
    • (1999) Cell. Mol. Life Sci. , vol.56 , pp. 523-537
    • Novak, A.1    Dedhar, S.2
  • 48
    • 67449128692 scopus 로고    scopus 로고
    • Wnt5A activates the calpain-mediated cleavage of filamin A
    • O'connell, M.P., Fiori, J.L., Baugher, K.M. et al. (2009). Wnt5A activates the calpain-mediated cleavage of filamin A. J. Invest. Dermatol. 129, 1782-1789.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 1782-1789
    • O'connell, M.P.1    Fiori, J.L.2    Baugher, K.M.3
  • 49
    • 0037055583 scopus 로고    scopus 로고
    • Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC
    • Reifenberger, J., Knobbe, C.B., Wolter, M., Blaschke, B., Schulte, K.W., Pietsch, T., Ruzicka, T., and Reifenberger, G. (2002). Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC. Int. J. Cancer 100, 549-556.
    • (2002) Int. J. Cancer , vol.100 , pp. 549-556
    • Reifenberger, J.1    Knobbe, C.B.2    Wolter, M.3    Blaschke, B.4    Schulte, K.W.5    Pietsch, T.6    Ruzicka, T.7    Reifenberger, G.8
  • 50
    • 0032937232 scopus 로고    scopus 로고
    • Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma
    • Rimm, D.L., Caca, K., Hu, G., Harrison, F.B., and Fearon, E.R. (1999). Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. Am. J. Pathol. 154, 325-329.
    • (1999) Am. J. Pathol. , vol.154 , pp. 325-329
    • Rimm, D.L.1    Caca, K.2    Hu, G.3    Harrison, F.B.4    Fearon, E.R.5
  • 53
    • 33845373278 scopus 로고    scopus 로고
    • Colorectal cancer and genetic alterations in the Wnt pathway
    • Segditsas, S., and Tomlinson, I. (2006). Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 25, 7531-7537.
    • (2006) Oncogene , vol.25 , pp. 7531-7537
    • Segditsas, S.1    Tomlinson, I.2
  • 54
    • 0037207269 scopus 로고    scopus 로고
    • Phosphorylation of glycogen synthase kinase-3beta at serine-9 by phospholipase Cgamma1 through protein kinase C in rat 3Y1 fibroblasts
    • Shin, S.Y., Yoon, S.C., Kim, Y.H., Kim, Y.S., and Lee, Y.H. (2002). Phosphorylation of glycogen synthase kinase-3beta at serine-9 by phospholipase Cgamma1 through protein kinase C in rat 3Y1 fibroblasts. Exp. Mol. Med. 34, 444-450.
    • (2002) Exp. Mol. Med. , vol.34 , pp. 444-450
    • Shin, S.Y.1    Yoon, S.C.2    Kim, Y.H.3    Kim, Y.S.4    Lee, Y.H.5
  • 55
    • 27744600102 scopus 로고    scopus 로고
    • Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas
    • Smith, A.P., Hoek, K., and Becker, D. (2005). Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas. Cancer Biol. Ther. 4, 1018-1029.
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 1018-1029
    • Smith, A.P.1    Hoek, K.2    Becker, D.3
  • 56
    • 10944234560 scopus 로고    scopus 로고
    • Melanocytes and the microphthalmia transcription factor network
    • Steingrimsson, E., Copeland, N.G., and Jenkins, N.A. (2004). Melanocytes and the microphthalmia transcription factor network. Annu. Rev. Genet. 38, 365-411.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 365-411
    • Steingrimsson, E.1    Copeland, N.G.2    Jenkins, N.A.3
  • 58
    • 59049093707 scopus 로고    scopus 로고
    • Wnt signaling in liver cancer
    • Takigawa, Y., and Brown, A.M. (2008). Wnt signaling in liver cancer. Curr. Drug Targets 9, 1013-1024.
    • (2008) Curr. Drug Targets , vol.9 , pp. 1013-1024
    • Takigawa, Y.1    Brown, A.M.2
  • 59
    • 3342979536 scopus 로고    scopus 로고
    • The transcription network regulating melanocyte development and melanoma
    • Vance, K.W., and Goding, C.R. (2004). The transcription network regulating melanocyte development and melanoma. Pigment Cell Res. 17, 318-325.
    • (2004) Pigment Cell Res. , vol.17 , pp. 318-325
    • Vance, K.W.1    Goding, C.R.2
  • 61
    • 0037119948 scopus 로고    scopus 로고
    • {beta}-Catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor
    • Widlund, H.R., Horstmann, M.A., Price, E.R., Cui, J., Lessnick, S.L., Wu, M., He, X., and Fisher, D.E. (2002). {beta}-Catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor. J. Cell Biol. 158, 1079-1087.
    • (2002) J. Cell Biol. , vol.158 , pp. 1079-1087
    • Widlund, H.R.1    Horstmann, M.A.2    Price, E.R.3    Cui, J.4    Lessnick, S.L.5    Wu, M.6    He, X.7    Fisher, D.E.8
  • 62
    • 0037013860 scopus 로고    scopus 로고
    • Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling
    • Yasumoto, K., Takeda, K., Saito, H., Watanabe, K., Takahashi, K., and Shibahara, S. (2002). Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling. EMBO J. 21, 2703-2714.
    • (2002) EMBO J. , vol.21 , pp. 2703-2714
    • Yasumoto, K.1    Takeda, K.2    Saito, H.3    Watanabe, K.4    Takahashi, K.5    Shibahara, S.6
  • 63
    • 79952601233 scopus 로고    scopus 로고
    • A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status
    • Zipser, M.C., Eichhoff, O.M., Widmer, D.S. et al. (2011). A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status. Pigment Cell Melanoma Res. 24, 326-333.
    • (2011) Pigment Cell Melanoma Res. , vol.24 , pp. 326-333
    • Zipser, M.C.1    Eichhoff, O.M.2    Widmer, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.