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Volumn 70, Issue 9, 2010, Pages 3813-3822

Microphthalmia-associated transcription factor controls the DNA damage response and a lineage-specific senescence program in melanomas

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYUREA; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PROTEIN P53;

EID: 77951743475     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-2913     Document Type: Article
Times cited : (104)

References (50)
  • 2
    • 21844478747 scopus 로고    scopus 로고
    • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
    • Garraway LA, Widlund HR, Rubin MA, et al. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 2005;436:117-122
    • (2005) Nature , vol.436 , pp. 117-122
    • Garraway, L.A.1    Widlund, H.R.2    Rubin, M.A.3
  • 3
    • 84887212492 scopus 로고    scopus 로고
    • Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: Clinical implications
    • Halaban R, Krauthammer M, Pelizzola M, et al. Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. PLoS One 2009;4:e4563.
    • (2009) PLoS One , vol.4
    • Halaban, R.1    Krauthammer, M.2    Pelizzola, M.3
  • 7
    • 70349609036 scopus 로고    scopus 로고
    • Simultaneous suppression of MITF and BRAF V600E enhanced inhibition of melanoma cell proliferation
    • Kido K, Sumimoto H, Asada S, et al. Simultaneous suppression of MITF and BRAF V600E enhanced inhibition of melanoma cell proliferation. Cancer Sci 2009;100:1863-1869
    • (2009) Cancer Sci , vol.100 , pp. 1863-1869
    • Kido, K.1    Sumimoto, H.2    Asada, S.3
  • 8
    • 44849094211 scopus 로고    scopus 로고
    • Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas
    • Dynek JN, Chan SM, Liu J, Zha J, Fairbrother WJ, Vucic D. Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas. Cancer Res 2008;68:3124-3132
    • (2008) Cancer Res , vol.68 , pp. 3124-3132
    • Dynek, J.N.1    Chan, S.M.2    Liu, J.3    Zha, J.4    Fairbrother, W.J.5    Vucic, D.6
  • 10
    • 33846929162 scopus 로고    scopus 로고
    • Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting Mitf
    • DOI 10.1038/sj.gt.3302868, PII 3302868
    • Nakai N, Kishida T, Shin-Ya M, et al. Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting Mitf. Gene Ther 2007;14:357-365 (Pubitemid 46231929)
    • (2007) Gene Therapy , vol.14 , Issue.4 , pp. 357-365
    • Nakai, N.1    Kishida, T.2    Shin-Ya, M.3    Imanishi, J.4    Ueda, Y.5    Kishimoto, S.6    Mazda, O.7
  • 11
    • 19544367637 scopus 로고    scopus 로고
    • Dynamic regulation of the human dopachrome tautomerase promoter by MITF, ER-α and chromatin remodelers during proliferation and senescence of human melanocytes
    • Schwahn DJ, Timchenko NA, Shibahara S, Medrano EE. Dynamic regulation of the human dopachrome tautomerase promoter by MITF, ER-α and chromatin remodelers during proliferation and senescence of human melanocytes. Pigment Cell Res 2005;18:203-213
    • (2005) Pigment Cell Res , vol.18 , pp. 203-213
    • Schwahn, D.J.1    Timchenko, N.A.2    Shibahara, S.3    Medrano, E.E.4
  • 14
  • 17
    • 34247505472 scopus 로고    scopus 로고
    • DNA repair pathways involved in anaphase bridge formation
    • DOI 10.1002/gcc.20425
    • Acilan C, Potter DM, Saunders WS. DNA repair pathways involved in anaphase bridge formation. Genes Chromosomes Cancer 2007;46: 522-531 (Pubitemid 46649567)
    • (2007) Genes Chromosomes and Cancer , vol.46 , Issue.6 , pp. 522-531
    • Acilan, C.1    Potter, D.M.2    Saunders, W.S.3
  • 18
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998;273:5858-5868
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 19
    • 0037378527 scopus 로고    scopus 로고
    • P53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice
    • DOI 10.1128/MCB.23.7.2556-2563.2003
    • Ward IM, Minn K, van Deursen J, Chen J. p53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. Mol Cell Biol 2003;23:2556-2563 (Pubitemid 36351034)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.7 , pp. 2556-2563
    • Ward, I.M.1    Minn, K.2    Van Deursen, J.3    Chen, J.4
  • 20
    • 36949005417 scopus 로고    scopus 로고
    • DNA damage signalling guards against activated oncogenes and tumour progression
    • DOI 10.1038/sj.onc.1210881, PII 1210881
    • Bartek J, Bartkova J, Lukas J. DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene 2007;26:7773-7779 (Pubitemid 350242463)
    • (2007) Oncogene , vol.26 , Issue.56 , pp. 7773-7779
    • Bartek, J.1    Bartkova, J.2    Lukas, J.3
  • 21
    • 61649093808 scopus 로고    scopus 로고
    • Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks
    • Shiotani B, Zou L. Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol Cell 2009;33:547-558
    • (2009) Mol Cell , vol.33 , pp. 547-558
    • Shiotani, B.1    Zou, L.2
  • 22
    • 0141619287 scopus 로고    scopus 로고
    • Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1
    • Veuger SJ, Curtin NJ, Richardson CJ, Smith GC, Durkacz BW. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1. Cancer Res 2003;63:6008-6015
    • (2003) Cancer Res , vol.63 , pp. 6008-6015
    • Veuger, S.J.1    Curtin, N.J.2    Richardson, C.J.3    Smith, G.C.4    Durkacz, B.W.5
  • 23
    • 0033552595 scopus 로고    scopus 로고
    • Regulation of p53 in response to DNA damage
    • Lakin ND, Jackson SP. Regulation of p53 in response to DNA damage. Oncogene 1999;18:7644-7655
    • (1999) Oncogene , vol.18 , pp. 7644-7655
    • Lakin, N.D.1    Jackson, S.P.2
  • 24
    • 53649106518 scopus 로고    scopus 로고
    • 15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation
    • 15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation. Cell Cycle 2008;7:3048-3055
    • (2008) Cell Cycle , vol.7 , pp. 3048-3055
    • Zhao, H.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 25
    • 33746616991 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
    • DOI 10.1038/ncb1448, PII NCB1448
    • KortleverRM, Higgins PJ, Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat Cell Biol 2006;8:877-884 (Pubitemid 44151592)
    • (2006) Nature Cell Biology , vol.8 , Issue.8 , pp. 878-884
    • Kortlever, R.M.1    Higgins, P.J.2    Bernards, R.3
  • 26
    • 0038793948 scopus 로고    scopus 로고
    • Apoptosis and melanoma chemoresistance
    • Soengas MS, Lowe SW. Apoptosis and melanoma chemoresistance. Oncogene 2003;22:3138-3151
    • (2003) Oncogene , vol.22 , pp. 3138-3151
    • Soengas, M.S.1    Lowe, S.W.2
  • 28
    • 5444227865 scopus 로고    scopus 로고
    • Guilty as charged: B-RAF is a human oncogene
    • DOI 10.1016/j.ccr.2004.09.022, PII S153561080400279X
    • Garnett MJ, Marais R. Guilty as charged: B-RAF is a human oncogene. Cancer Cell 2004;6:313-319 (Pubitemid 39361432)
    • (2004) Cancer Cell , vol.6 , Issue.4 , pp. 313-319
    • Garnett, M.J.1    Marais, R.2
  • 29
    • 56149126490 scopus 로고    scopus 로고
    • C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells
    • Zhuang D, Mannava S, Grachtchouk V, et al. C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells. Oncogene 2008;27:6623-6634
    • (2008) Oncogene , vol.27 , pp. 6623-6634
    • Zhuang, D.1    Mannava, S.2    Grachtchouk, V.3
  • 31
    • 34447635892 scopus 로고    scopus 로고
    • Dynamic assembly of chromatin complexes during cellular senescence: Implications for the growth arrest of human melanocytic nevi
    • DOI 10.1111/j.1474-9726.2007.00308.x
    • Bandyopadhyay D, Curry JL, Lin Q, et al. Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi. Aging Cell 2007;6: 577-591 (Pubitemid 47087062)
    • (2007) Aging Cell , vol.6 , Issue.4 , pp. 577-591
    • Bandyopadhyay, D.1    Curry, J.L.2    Lin, Q.3    Richards, H.W.4    Chen, D.5    Hornsby, P.J.6    Timchenko, N.A.7    Medrano, E.E.8
  • 33
    • 19544392134 scopus 로고    scopus 로고
    • CDK2 translational down-regulation during endothelial senescence
    • DOI 10.1016/j.yexcr.2005.03.025, PII S0014482705001503
    • Freedman DA, Folkman J. CDK2 translational down-regulation during endothelial senescence. Exp Cell Res 2005;307:118-130 (Pubitemid 40732738)
    • (2005) Experimental Cell Research , vol.307 , Issue.1 , pp. 118-130
    • Freedman, D.A.1    Folkman, J.2
  • 34
    • 33846128155 scopus 로고    scopus 로고
    • The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence
    • DOI 10.1101/gad.1487307
    • Mallette FA, Gaumont-Leclerc MF, Ferbeyre G. The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. Genes Dev 2007;21:43-48 (Pubitemid 46089705)
    • (2007) Genes and Development , vol.21 , Issue.1 , pp. 43-48
    • Mallette, F.A.1    Gaumont-Leclerc, M.-F.2    Ferbeyre, G.3
  • 35
    • 15744386741 scopus 로고    scopus 로고
    • Regulation of CHK2 by DNA-dependent protein kinase
    • DOI 10.1074/jbc.M412445200
    • Li J, Stern DF. Regulation of CHK2 by DNA-dependent protein kinase. J Biol Chem 2005;280:12041-12050 (Pubitemid 40418523)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.12 , pp. 12041-12050
    • Li, J.1    Stern, D.F.2
  • 37
    • 23844476499 scopus 로고    scopus 로고
    • p53-dependent transcriptional repression of c-myc is required for G1 cell cycle arrest
    • Ho JS, Ma W, Mao DY, Benchimol S. p53-dependent transcriptional repression of c-myc is required for G1 cell cycle arrest. Mol Cell Biol 2005;25:7423-7431
    • (2005) Mol Cell Biol , vol.25 , pp. 7423-7431
    • Ho, J.S.1    Ma, W.2    Mao, D.Y.3    Benchimol, S.4
  • 38
    • 14644410453 scopus 로고    scopus 로고
    • The signals and pathways activating cellular senescence
    • Ben-Porath I, Weinberg RA. The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 2005;37:961-976
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 961-976
    • Ben-Porath, I.1    Weinberg, R.A.2
  • 39
    • 33747192833 scopus 로고    scopus 로고
    • Cellular senescence in naevi and immortalisation in melanoma: A role for p16?
    • Gray-Schopfer VC, Cheong SC, Chong H, et al. Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br J Cancer 2006;95:496-505.
    • (2006) Br J Cancer , vol.95 , pp. 496-505
    • Gray-Schopfer, V.C.1    Cheong, S.C.2    Chong, H.3
  • 40
    • 13944273767 scopus 로고    scopus 로고
    • Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression
    • Carreira S, Goodall J, Aksan I, et al. Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression. Nature 2005;433:764-769
    • (2005) Nature , vol.433 , pp. 764-769
    • Carreira, S.1    Goodall, J.2    Aksan, I.3
  • 41
    • 1642396456 scopus 로고    scopus 로고
    • Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor
    • Prince S, Carreira S, Vance KW, Abrahams A, Goding CR. Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor. Cancer Res 2004;64:1669-1674
    • (2004) Cancer Res , vol.64 , pp. 1669-1674
    • Prince, S.1    Carreira, S.2    Vance, K.W.3    Abrahams, A.4    Goding, C.R.5
  • 42
    • 58149236959 scopus 로고    scopus 로고
    • Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells
    • Viale A, De Franco F, Orleth A, et al. Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells. Nature 2009;457:51-56
    • (2009) Nature , vol.457 , pp. 51-56
    • Viale, A.1    De Franco, F.2    Orleth, A.3
  • 43
    • 0028228649 scopus 로고
    • Urokinase-type and tissue-type plasminogen activators as growth factors of human fibroblasts
    • De Petro G, Copeta A, Barlati S. Urokinase-type and tissue-type plasminogen activators as growth factors of human fibroblasts. Exp Cell Res 1994;213:286-294
    • (1994) Exp Cell Res , vol.213 , pp. 286-294
    • De Petro, G.1    Copeta, A.2    Barlati, S.3
  • 44
    • 8644254467 scopus 로고    scopus 로고
    • In vivo overexpression of tumstatin domains by tumor cells inhibits their invasive properties in a mouse melanoma model
    • Pasco S, Ramont L, Venteo L, Pluot M, Maquart FX, Monboisse JC. In vivo overexpression of tumstatin domains by tumor cells inhibits their invasive properties in a mouse melanoma model. Exp Cell Res 2004;301:251-265
    • (2004) Exp Cell Res , vol.301 , pp. 251-265
    • Pasco, S.1    Ramont, L.2    Venteo, L.3    Pluot, M.4    Maquart, F.X.5    Monboisse, J.C.6
  • 45
    • 0033580135 scopus 로고    scopus 로고
    • p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells
    • Eymin B, Haugg M, Droin N, Sordet O, Dimanche-Boitrel MT, Solary E. p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells. Oncogene 1999;18:1411-1418
    • (1999) Oncogene , vol.18 , pp. 1411-1418
    • Eymin, B.1    Haugg, M.2    Droin, N.3    Sordet, O.4    Dimanche-Boitrel, M.T.5    Solary, E.6
  • 47
    • 22844445932 scopus 로고    scopus 로고
    • Use of human tissue to assess the oncogenic activity of melanoma-associated mutations
    • Chudnovsky Y, Adams AE, Robbins PB, Lin Q, Khavari PA. Use of human tissue to assess the oncogenic activity of melanoma-associated mutations. Nat Genet 2005;37:745-749
    • (2005) Nat Genet , vol.37 , pp. 745-749
    • Chudnovsky, Y.1    Adams, A.E.2    Robbins, P.B.3    Lin, Q.4    Khavari, P.A.5
  • 48
    • 67049168909 scopus 로고    scopus 로고
    • The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes
    • Yu H, McDaid R, Lee J, et al. The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes. Am J Pathol 2009;174:2367-2377
    • (2009) Am J Pathol , vol.174 , pp. 2367-2377
    • Yu, H.1    McDaid, R.2    Lee, J.3
  • 49
    • 0033637120 scopus 로고    scopus 로고
    • Deregulation of the Rb and p53 pathways in uveal melanoma
    • Brantley MA, Jr., Harbour JW. Deregulation of the Rb and p53 pathways in uveal melanoma. Am J Pathol 2000;157:1795-1801
    • (2000) Am J Pathol , vol.157 , pp. 1795-1801
    • Brantley Jr., M.A.1    Harbour, J.W.2
  • 50
    • 0031975083 scopus 로고    scopus 로고
    • Prognostic implications of p53 overexpression in cutaneous melanoma from sun-exposed and nonexposed sites
    • Essner R, Kuo CT, Wang H, et al. Prognostic implications of p53 overexpression in cutaneous melanoma from sun-exposed and nonexposed sites. Cancer 1998;82:309-316
    • (1998) Cancer , vol.82 , pp. 309-316
    • Essner, R.1    Kuo, C.T.2    Wang, H.3


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