Merging bioactivity with liquid chromatography-mass spectrometry-based chemometrics to identify minor immunomodulatory compounds from a Micronesian adaptogen, Phaleria nisidai

Journal of Chromatography A

Volumn 1364, Issue , 2014, Pages 74-82

  Kulakowski, Daniel M ^a   Wu, Shi Biao ^a   Balick, Michael J ^b   Kennelly, Edward J ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b INSTITUTE OF ECONOMIC BOTANY   (United States)

Author keywords

Chemometrics; Daphnane diterpenes; Immunomodulation; LC TOF MS; Multivariate statistics; Thymelaeceae

Indexed keywords

DATA HANDLING; DRUG PRODUCTS; ESTERS; INDUCTIVELY COUPLED PLASMA; MASS SPECTROMETRY; METABOLITES; MULTIVARIANT ANALYSIS; OLEFINS; STATISTICAL MECHANICS;

CHEMOMETRICS; DITERPENES; IMMUNO MODULATIONS; LC-TOF-MS; MULTIVARIATE STATISTICS; THYMELAECEAE;

LIQUID CHROMATOGRAPHY;

ACETOXYHURATOXIN; DITERPENE; GAMMA INTERFERON; GENKWANINE D; GENKWANINE H; HURATOXIN; IMMUNOMODULATING AGENT; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 6; PHALERIA NISIDAI EXTRACT; PLANT EXTRACT; PROSTRATIN; SIMPLEXIN; STELLERAMACRIN B; TERPENOID; UNCLASSIFIED DRUG; CYTOKINE; ESTER; IMMUNOLOGIC FACTOR; MEZEREIN; TERPENE;

ARTICLE; CHEMOMETRIC ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEDERATED STATES OF MICRONESIA; FRACTIONATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSTIMULATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHALERIA NISIDAI; REVERSED PHASE LIQUID CHROMATOGRAPHY; THYMELAEACEAE; TIME OF FLIGHT MASS SPECTROMETRY; BLOOD; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; MONONUCLEAR CELL; PROCEDURES;

PHALERIA; THYMELAEACEAE;

CHROMATOGRAPHY, REVERSE-PHASE; CYTOKINES; DITERPENES; ESTERS; HUMANS; IMMUNOLOGIC FACTORS; LEUKOCYTES, MONONUCLEAR; MASS SPECTROMETRY; PLANT EXTRACTS; TERPENES; THYMELAEACEAE;

EID: 84915786246     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.08.049     Document Type: Article

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