The tumor cytosol miRNAs, fluid miRNAs and exosome miRNAs in lung cancer

Frontiers in Oncology

Volumn 4, Issue NOV, 2014, Pages

  Qin, Xin ^a,b,c   Xu, Haisheng ^b   Gong, Wenrong ^a   Deng, Wenbin ^a,c  

^a HUBEI UNIVERSITY OF ARTS AND SCIENCE   (China)

^b Xiangyang Central Hospital   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biomarker; Lung cancer; microRNA

Indexed keywords

MICRORNA; MICRORNA 106A; MICRORNA 1254; MICRORNA 141; MICRORNA 146; MICRORNA 155; MICRORNA 17 3P; MICRORNA 191; MICRORNA 192; MICRORNA 203; MICRORNA 205; MICRORNA 21; MICRORNA 210; MICRORNA 212; MICRORNA 214; MICRORNA 361 3P; MICRORNA 574; MICRORNA 625; UNCLASSIFIED DRUG;

APOPTOSIS; BODY FLUID; CARCINOGENESIS; EPIGENETICS; GENE EXPRESSION; HUMAN; HYPOXIA; LUNG CANCER; NON SMALL CELL LUNG CANCER; REVIEW;

EID: 84915784783     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2014.00357     Document Type: Review

References (64)

1. DeSantis CE, Lin CC, Mariotto AB, Siegel RL, Stein KD, Kramer JL, Alteri R, Robbins AS, Jemal A. Cancer treatment and survivorship statistics, 2014. CA Cancer J Clin.2014 Jun 1.doi: 10.3322/caac.21235. [Epub ahead of print]
2. Mallick R, Patnaik SK, Yendamuri S. MicroRNAs and lung cancer: Biology and applications in diagnosis and prognosis. J Carcinog.2010; 9.pii: 8
3. Dali Zheng, Shadi Haddadin, Yong Wang, Li Qun Gu, Michael C. Perry, Carl E. Freter, Michael X. Wang. Plasma microRNAs as novel biomarkers for early detection of lung cancer. Int J Clin Exp Pathol, 2011; 4(6):575-586
4. Bartel, D.P. MicroRNAs: target recognition and regulatory functions. Cell. 2009; 136(2): 215-233.
5. Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993; 75(5):843-54.
6. Kozomara A, Griffiths-Jones S. miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res. 2014; 42(Database issue):D68-73.
7. Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M, Stephens RM, Okamoto A, Yokota J, Tanaka T, Calin GA, Liu CG, Croce CM, Harris CC. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell. 2006; 9(3):189-98.
8. Lin PY, Yu SL, Yang PC. MicroRNA in lung cancer. Br J Cancer. 2010; 103(8): 1144-8.
9. Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, Harano T, Yatabe Y, Nagino M, Nimura Y, Mitsudomi T, Takahashi T. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 2004; 64(11): 3753-6.
10. Johnson SM, Grosshans H, Shingara J et al. RAS is regulated by the let-7 microRNA family. Cell 2005; 120(5): 635-47.
11. Lee YS, Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev. 2007; 21(9):1025-1030.
12. Meyer B, Loeschke S, Schultze A, Weigel T, Sandkamp M, Goldmann T, Vollmer E, Bullerdiek J. HMGA2 overexpression in non-small cell lung cancer. Mol Carcinog.2007; 46(7): 503-511.
13. Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet, 2007; 39(5):673-677.
14. Koscianska E, Baev V, Skreka K, Oikonomaki K, Rusinov V, Tabler M, Kalantidis K. Prediction and preliminary validation of oncogene regulation by miRNAs. BMC Mol Biol, 2007; 8(1):79.
15. Johnson CD, Esquela-Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown D, Slack FJ. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 2007; 67(16):7713-7722.
16. Ota, A., Tagawa, H., Karnan, S., Tsuzuki, S., Karpas, A., Kira, S., Yoshida, Y., and Seto, M. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res. 2004; 64(9), 3087-3095.
17. Hayashita Y, Osada H, Tatematsu Y et al. A polycistronic microRNA cluster, miR- 17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005; 65(21): 9628-32.
18. Davidson MR, Larsen JE, Yang IA, Hayward NK, Clarke BE, Duhig EE, Passmore LH, Bowman RV, Fong KM. MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma. PLoS One. 2010; 5(9):e12560
19. Mark E. Hatley, DavidM. Patrick, MatthewR. Garcia, James A. Richardson, RhondaBassel-Duby, Eva van Rooij, Eric N. Olson, Modulation of K-Ras- Dependent Lung Tumorigenesis by microRNA-21. Cancer Cell, 2010; 18, 282-293
20. Akira Mogi and Hiroyuki Kuwano, TP53 Mutations in Nonsmall Cell Lung Cancer. J Biomed Biotechnol. 2011; 2011:583929
21. He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW, Cleary MA, Hannon GJ. A microRNA component of the p53 tumour suppressor network. Nature. 2007; 447(7148):1130-4.
22. Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ. 2010; 17(2): 193-9.
23. Yamakuchi M, Lowenstein q. MiR-34, SIRT1 and p53:the feedback loop. Cell Cycle, 2009; 8(5):712-715.
24. Kasinski AL1, Slack FJ.miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. Cancer Res. 2012; 72(21):5576-87.
25. Liu B, Peng XC, Zheng XL, Wang J, Qin YW. MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer. 2009; 66(2):169-75.
26. Crawford M, Brawner E, Batte K, Yu L, Hunter MG, Otterson GA, Nuovo G, Marsh CB, Nana-Sinkam SP. MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines. Biochem Biophy Res Commun. 2008; 373(4):607-612.
27. Feller, S. M. Crk family adaptors-signalling complex formation and biological roles. Oncogene. 2001; 20(44):6348-6371.
28. Kobashigawa Y, Sakai M, Naito M, Yokochi M, Kumeta H, Makino Y, Ogura K, Tanaka S, Inagaki F. Structural basis for the transforming activity of human cancerrelated signaling adaptor protein CRK. Nat Struct Mol Biol. 2007; 14(6):503-510.
29. Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, Goodall GJ, Thilaganathan N, Du L, Zhang Y, Pertsemlidis A, Kurie JM. Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev. 2009; 23(18):2140-2151
30. Jiang L, Huang Q, Zhang S, Zhang Q, Chang J, Qiu X, Wang E. Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells. BMC Cancer. 2010; 10:318.
31. Zhang JG, Wang JJ, Zhao F, Liu Q, Jiang K, Yang GH. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin ChimActa. 2010; 411(11-12):846-52.
32. Savita U, Karunagaran D. BiochemBiophys Res Commun. 2013; 434(4):841-7.
33. Zhu W, Shan X, Wang T, Shu Y, Liu P.miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int J Cancer.2010; 127(11):2520-9.
34. Galluzzi L, Morselli E, Vitale I, Kepp O, Senovilla L, Criollo A, Servant N, Paccard C, Hupé P, Robert T, Ripoche H, Lazar V, Harel-Bellan A, Dessen P, Barillot E, Kroemer G.miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res. 2010;70(5):1793-803.
35. Chatterjee A, Chattopadhyay D, Chakrabarti G. miR-17-5p Downregulation Contributes to Paclitaxel Resistance of Lung Cancer Cells through Altering Beclin1 Expression. PLoS One. 2014; 9(4):e95716.
36. Zhong M, Ma X, Sun C, Chen L. MicroRNAsreduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer. Chem Biol Interact. 2010; 84(3): 431-8.
37. Weber, J. A., Baxter, D. H., Zhang, S., Huang, D. Y., Huang, K. H., Lee, M. J., Galas, D. J., and Wang, K. The microRNA spectrum in 12 body fluids. Clin. Chem. 2010; 56, 1733-1741
38. Tzimagiorgis, G., Michailidou, E. Z., Kritis, A., Markopoulos, A. K., and Kouidou, S. Recovering circulating extracellular or cell-free RNA from bodily fluids. Cancer Epidemiol. 2011; 35, 580-589.
39. Mitchell P S, Parkin R K, Kroh E M, et al. Circulating microRNAs as stable bloodbased markers for cancer detection. Proc Natl Acad Sci USA, 2008;105:10513-10518
40. Chen X, Ba Y, Ma L, et al. Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res, 2008; 18: 997-1006
41. Roth C, Kasimir-Bauer S, Pantel K, et al. Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer. Mol Oncol, 2011;5(3): 281-91.
42. Foss KM, Sima C, Ugolini D, et al. MiR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer. J Thorac Oncol, 2011; 6:482-488
43. Chang Liu, Youping Deng, Leilei Wang, Yong Mei, and Rui Zhang. Early Diagnostic Value of Circulating MiRNA-21 in Lung Cancer: A Meta-Analysis. Tsinghua Science and Technology. 2013;18(5): 441-445
44. Roth C, Stückrath I, Pantel K, Izbicki JR, Tachezy M, Schwarzenbach H. Low levels of cell-free circulating miR-361-3p and miR-625* as blood-based markers for discriminating malignant from benign lung tumors. PLoS One. 2012; 7(6):e38248.
45. Roth C, Kasimir-Bauer S, Pantel K, Schwarzenbach H. Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer. Mol Oncol. 2011; 5(3):281-91.
46. Zhibin Hu, Xi Chen, Yang Zhao, et al. Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol, 2010;28:1721-1726
47. Boeri M, Verri C, Conte D,.MicroRNA signatures in tissues and cancer. Cancer Imaging, 2011; 6, 9-12.
48. Guoku Hu, Kristen M. Drescher, Xian Ming Chen. Exosomal miRNAs: biological properties and therapeutic potential. Frontiers in genetics.2012; 3:56.doi: 10.3389/fgene.2012.00056. eCollection 2012.
49. Riccardo Cazzoli, PhD1,4, Fiamma Buttitta, Marta Di Nicola, Sara Malatesta, Antonio Marchetti, Harvey I. Pass, MicroRNAs derived from circulating exosomes as non-invasive biomarkers for screening and diagnose lung cancer. J Thorac Oncol. 2013; 8(9): 1156-1162.
50. Rabinowits, G., Gercel-Taylor, C., Day, J. M., Taylor, D. D., and Kloecker, G. H. Exosomal microRNA: a diagnostic marker for lungcancer. Clin. Lung Cancer, 2009; 10, 42-46.
51. Gilad S, Meiri E, Yogev Y, et al. Serum microRNAs are promising novel biomarkers. PLoS One, 2008; 3: e3148
52. Tie Y1, Liu B, Fu H, Zheng X. Circulating miRNA and cancer diagnosis. Sci China C Life Sci. 2009; 52(12):1117-22.
53. Chiba M, Kimura M, Asari S., Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines. Oncol Rep. 2012; 28(5):1551-8.
54. Vasily N. Aushev, Irina B. Zborovskaya, Konstantin K. Laktionov, Nicolas Girard, Marie-Pierre Cros, ZdenkoHerceg, Vladimir Krutovskikh. Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma. PLoS One, 2013; 8(10):e78649
55. Alessia Gallo, Mayank Tandon, Ilias Alevizos, Gabor G. Illei. The majority of microRNAs detectable in serum and saliva isconcentrated in exosomes. PLoS One, 2012; 7(3):e30679).
56. Cheng G. Circulating miRNAs: Roles in cancer diagnosis, prognosis and therapy. Adv Drug Deliv Rev. 2014 Sep 16. pii: S0169-409X(14)00199-9. doi: 10.1016/j.addr.2014.09.001. [Epub ahead of print]
57. Filipowicz W1, Bhattacharyya SN, Sonenberg N. Mechanisms of posttranscriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet. 2008; 9(2):102-14.
58. Lee YS, Pressman S, Andress AP, et al. Silencing by small RNAs is linked to endosomaltraffcking. Nat Cell Biol. 2009; 11(9):1150-1156.
59. Gibbings DJ, Ciaudo C, Erhardt M, Voinnet O. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat Cell Biol. 2009; 11(9):1143-1149.
60. Raponi, M., Dossey, L., Jatkoe, T., Wu, X., Chen, G., Fan, H., and Beer, D. G. MicroRNA classifiers for predicting prognosis of squamous cell lung cancer. Cancer Res. 2009; 69, 5776-5783.
61. Villarroya-Beltri C, Gutierrez-Vazquez C, Sanchez-Cabo F, Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specifc motifs. Nat Commun. 2013; 4:2980.
62. Leidinger P1, Keller A, Meese E. MicroRNAs-Important Molecules in Lung Cancer Research. Front Genet. 2012, 23; 2:104.
63. Turchinovich A, Weiz L, Langheinz A, BurwinkelB Characterization of extracellular circulating microRNA. Nucleic Acids Res, 2011; 39(16): 7223-33.
64. Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, Mitchell PS, Bennett CF, Pogosova-Agadjanyan EL, Stirewalt DL, Tait JF, Tewari M. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci USA, 2011; 108(12):5003-5008.