메뉴 건너뛰기




Volumn 464, Issue 3, 2014, Pages 365-375

Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20

Author keywords

Inpp5e; Phagocytosis; Phagosome maturation; PtdIns3P; Rab20; Rab5

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; PEPTIDES AND PROTEINS; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN INPP5E; RAB PROTEIN; RAB20 PROTEIN; UNCLASSIFIED DRUG; ACID; PHOSPHATASE; PHOSPHOINOSITIDE 5-PHOSPHATASE; POLYPHOSPHOINOSITIDE; PROTEIN BINDING; RAB20 PROTEIN, MOUSE;

EID: 84915766664     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140916     Document Type: Article
Times cited : (16)

References (42)
  • 1
    • 64749091309 scopus 로고    scopus 로고
    • Antimicrobial mechanisms of phagocytes and bacterial evasion strategies
    • CrossRef PubMed
    • Flannagan, R. S., Cosío, G. and Grinstein, S. (2009) Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nat. Rev. Microbiol. 7, 355-366 CrossRef PubMed
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 355-366
    • Flannagan, R.S.1    Cosío, G.2    Grinstein, S.3
  • 2
    • 52449127462 scopus 로고    scopus 로고
    • Phagosome maturation: Going through the acid test
    • CrossRef PubMed
    • Kinchen, J. M. and Ravichandran, K. S. (2008) Phagosome maturation: going through the acid test. Nat. Rev. Mol. Cell Biol. 9, 781-795 CrossRef PubMed
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 781-795
    • Kinchen, J.M.1    Ravichandran, K.S.2
  • 3
    • 47749107873 scopus 로고    scopus 로고
    • Shaping cups into phagosomes and macropinosomes
    • CrossRef PubMed
    • Swanson, J. A. (2008) Shaping cups into phagosomes and macropinosomes. Nat. Rev. Mol. Cell Biol. 9, 639-649 CrossRef PubMed
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 639-649
    • Swanson, J.A.1
  • 4
    • 33645078650 scopus 로고    scopus 로고
    • Regulation of membrane traffic by phosphoinositide 3-kinases
    • CrossRef PubMed
    • Lindmo, K. and Stenmark, H. (2006) Regulation of membrane traffic by phosphoinositide 3-kinases. J. Cell Sci. 119, 605-614 CrossRef PubMed
    • (2006) J. Cell Sci. , vol.119 , pp. 605-614
    • Lindmo, K.1    Stenmark, H.2
  • 5
    • 0036532121 scopus 로고    scopus 로고
    • Roles of PI3Ks in leukocyte chemotaxis and phagocytosis
    • CrossRef PubMed
    • Stephens, L., Ellson, C. and Hawkins, P. (2002) Roles of PI3Ks in leukocyte chemotaxis and phagocytosis. Curr. Opin. Cell Biol. 14, 203-213 CrossRef PubMed
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 203-213
    • Stephens, L.1    Ellson, C.2    Hawkins, P.3
  • 6
    • 34548550595 scopus 로고    scopus 로고
    • Lipid signaling and the modulation of surface charge during phagocytosis
    • CrossRef PubMed
    • Yeung, T. and Grinstein, S. (2007) Lipid signaling and the modulation of surface charge during phagocytosis. Immunol. Rev. 219, 17-36 CrossRef PubMed
    • (2007) Immunol. Rev. , vol.219 , pp. 17-36
    • Yeung, T.1    Grinstein, S.2
  • 7
    • 0035954430 scopus 로고    scopus 로고
    • Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis
    • CrossRef PubMed
    • Marshall, J. G., Booth, J. W., Stambolic, V., Mak, T., Balla, T., Schreiber, A. D., Meyer, T. and Grinstein, S. (2001) Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis. J. Cell Biol. 153, 1369-1380 CrossRef PubMed
    • (2001) J. Cell Biol. , vol.153 , pp. 1369-1380
    • Marshall, J.G.1    Booth, J.W.2    Stambolic, V.3    Mak, T.4    Balla, T.5    Schreiber, A.D.6    Meyer, T.7    Grinstein, S.8
  • 8
    • 0030459125 scopus 로고    scopus 로고
    • A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages
    • CrossRef PubMed
    • Araki, N., Johnson, M. T. and Swanson, J. A. (1996) A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages. J. Cell Biol. 135, 1249-1260 CrossRef PubMed
    • (1996) J. Cell Biol. , vol.135 , pp. 1249-1260
    • Araki, N.1    Johnson, M.T.2    Swanson, J.A.3
  • 9
    • 0033555931 scopus 로고    scopus 로고
    • A requirement for phosphatidylinositol 3-kinase in pseudopod extension
    • CrossRef PubMed
    • Cox, D., Tseng, C. C., Bjekic, G. and Greenberg, S. (1999) A requirement for phosphatidylinositol 3-kinase in pseudopod extension. J. Biol. Chem. 274, 1240-1247 CrossRef PubMed
    • (1999) J. Biol. Chem. , vol.274 , pp. 1240-1247
    • Cox, D.1    Tseng, C.C.2    Bjekic, G.3    Greenberg, S.4
  • 11
    • 0035817635 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest
    • CrossRef PubMed
    • Fratti, R. A., Backer, J. M., Gruenberg, J., Corvera, S. and Deretic, V. (2001) Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J. Cell Biol. 154, 631-644 CrossRef PubMed
    • (2001) J. Cell Biol. , vol.154 , pp. 631-644
    • Fratti, R.A.1    Backer, J.M.2    Gruenberg, J.3    Corvera, S.4    Deretic, V.5
  • 12
    • 0037106460 scopus 로고    scopus 로고
    • Phagosome maturation: Aging gracefully
    • PubMed
    • Vieira, O. V., Botelho, R. J. and Grinstein, S. (2002) Phagosome maturation: aging gracefully. Biochem. J. 366, 689-704 PubMed
    • (2002) Biochem. J. , vol.366 , pp. 689-704
    • Vieira, O.V.1    Botelho, R.J.2    Grinstein, S.3
  • 15
    • 15244340430 scopus 로고    scopus 로고
    • Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis
    • CrossRef PubMed
    • Vergne, I., Chua, J., Lee, H. H., Lucas, M., Belisle, J. and Deretic, V. (2005) Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 102, 4033-4038 CrossRef PubMed
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 4033-4038
    • Vergne, I.1    Chua, J.2    Lee, H.H.3    Lucas, M.4    Belisle, J.5    Deretic, V.6
  • 16
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • CrossRef PubMed
    • Engelman, J. A., Luo, J. and Cantley, L. C. (2006) The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 7, 606-619 CrossRef PubMed
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 17
    • 62749155738 scopus 로고    scopus 로고
    • The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease
    • CrossRef PubMed
    • Ooms, L. M., Horan, K. A., Rahman, P., Seaton, G., Gurung, R., Kethesparan, D. S. and Mitchell, C. A. (2009) The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease. Biochem. J. 419, 29-49 CrossRef PubMed
    • (2009) Biochem. J. , vol.419 , pp. 29-49
    • Ooms, L.M.1    Horan, K.A.2    Rahman, P.3    Seaton, G.4    Gurung, R.5    Kethesparan, D.S.6    Mitchell, C.A.7
  • 18
    • 70349763941 scopus 로고    scopus 로고
    • Specific role of phosphoinositide 3-kinase p110alpha in the regulation of phagocytosis and pinocytosis in macrophages
    • CrossRef PubMed
    • Tamura, N., Hazeki, K., Okazaki, N., Kametani, Y., Murakami, H., Takaba, Y., Ishikawa, Y., Nigorikawa, K. and Hazeki, O. (2009) Specific role of phosphoinositide 3-kinase p110alpha in the regulation of phagocytosis and pinocytosis in macrophages. Biochem. J. 423, 99-108 CrossRef PubMed
    • (2009) Biochem. J. , vol.423 , pp. 99-108
    • Tamura, N.1    Hazeki, K.2    Okazaki, N.3    Kametani, Y.4    Murakami, H.5    Takaba, Y.6    Ishikawa, Y.7    Nigorikawa, K.8    Hazeki, O.9
  • 19
    • 30444450889 scopus 로고    scopus 로고
    • The inositol phosphatase SHIP-2 down-regulates FcgammaR-mediated phagocytosis in murine macrophages independently of SHIP-1
    • CrossRef PubMed
    • Ai, J., Maturu, A., Johnson, W., Wang, Y., Marsh, C. B. and Tridandapani, S. (2006) The inositol phosphatase SHIP-2 down-regulates FcgammaR-mediated phagocytosis in murine macrophages independently of SHIP-1. Blood 107, 813-820 CrossRef PubMed
    • (2006) Blood , vol.107 , pp. 813-820
    • Ai, J.1    Maturu, A.2    Johnson, W.3    Wang, Y.4    Marsh, C.B.5    Tridandapani, S.6
  • 20
    • 1842424697 scopus 로고    scopus 로고
    • The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports toll-like receptor 4 signaling in murine peritoneal macrophages
    • CrossRef PubMed
    • Cao, X., Wei, G., Fang, H., Guo, J., Weinstein, M., Marsh, C. B., Ostrowski, M. C. and Tridandapani, S. (2004) The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports toll-like receptor 4 signaling in murine peritoneal macrophages. J. Immunol. 172, 4851-4857 CrossRef PubMed
    • (2004) J. Immunol. , vol.172 , pp. 4851-4857
    • Cao, X.1    Wei, G.2    Fang, H.3    Guo, J.4    Weinstein, M.5    Marsh, C.B.6    Ostrowski, M.C.7    Tridandapani, S.8
  • 21
    • 39649123775 scopus 로고    scopus 로고
    • Regulation of FcgammaR-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3 mediated phagocytosis by differential recruitment of these 5-phosphatases to the phagocytic cup
    • CrossRef PubMed
    • Horan, K. A., Watanabe, K., Kong, A. M., Bailey, C. G., Rasko, J. E., Sasaki, T. and Mitchell, C. A. (2007) Regulation of FcgammaR-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3 mediated phagocytosis by differential recruitment of these 5-phosphatases to the phagocytic cup. Blood 110, 4480-4491 CrossRef PubMed
    • (2007) Blood , vol.110 , pp. 4480-4491
    • Horan, K.A.1    Watanabe, K.2    Kong, A.M.3    Bailey, C.G.4    Rasko, J.E.5    Sasaki, T.6    Mitchell, C.A.7
  • 22
    • 84862726617 scopus 로고    scopus 로고
    • Coordination between RAB GTPase and phosphoinositide regulation and functions
    • CrossRef PubMed
    • Jean, S. and Kiger, A. A. (2012) Coordination between RAB GTPase and phosphoinositide regulation and functions. Nat. Rev. Mol. Cell Biol. 13, 463-470 CrossRef PubMed
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 463-470
    • Jean, S.1    Kiger, A.A.2
  • 23
    • 84864134613 scopus 로고    scopus 로고
    • How nascent phagosomes mature to become phagolysosomes
    • CrossRef PubMed
    • Fairn, G. D. and Grinstein, S. (2012) How nascent phagosomes mature to become phagolysosomes. Trends Immunol. 33, 397-405 CrossRef PubMed
    • (2012) Trends Immunol. , vol.33 , pp. 397-405
    • Fairn, G.D.1    Grinstein, S.2
  • 24
    • 78449274207 scopus 로고    scopus 로고
    • Analysis of phagosomal proteomes: From latex-bead to bacterial phagosomes
    • CrossRef PubMed
    • Li, Q., Jagannath, C., Rao, P. K., Singh, C. R. and Lostumbo, G. (2010) Analysis of phagosomal proteomes: from latex-bead to bacterial phagosomes. Proteomics 10, 4098-4116 CrossRef PubMed
    • (2010) Proteomics , vol.10 , pp. 4098-4116
    • Li, Q.1    Jagannath, C.2    Rao, P.K.3    Singh, C.R.4    Lostumbo, G.5
  • 26
    • 84855407584 scopus 로고    scopus 로고
    • Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling
    • CrossRef PubMed
    • Bohdanowicz, M., Balkin, D. M., De Camilli, P. and Grinstein, S. (2012) Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Mol. Biol. Cell 23, 176-187 CrossRef PubMed
    • (2012) Mol. Biol. Cell , vol.23 , pp. 176-187
    • Bohdanowicz, M.1    Balkin, D.M.2    De Camilli, P.3    Grinstein, S.4
  • 28
    • 17344377424 scopus 로고    scopus 로고
    • A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
    • CrossRef PubMed
    • Horiuchi, H., Lippé, R., McBride, H. M., Rubino, M., Woodman, P., Stenmark, H., Rybin, V., Wilm, M., Ashman, K., Mann, M. and Zerial, M. (1997) A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell 90, 1149-1159 CrossRef PubMed
    • (1997) Cell , vol.90 , pp. 1149-1159
    • Horiuchi, H.1    Lippé, R.2    McBride, H.M.3    Rubino, M.4    Woodman, P.5    Stenmark, H.6    Rybin, V.7    Wilm, M.8    Ashman, K.9    Mann, M.10    Zerial, M.11
  • 29
    • 0035171352 scopus 로고    scopus 로고
    • Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex
    • CrossRef PubMed
    • Lippé, R., Miaczynska, M., Rybin, V., Runge, A. and Zerial, M. (2001) Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex. Mol. Biol. Cell 12, 2219-2228 CrossRef PubMed
    • (2001) Mol. Biol. Cell , vol.12 , pp. 2219-2228
    • Lippé, R.1    Miaczynska, M.2    Rybin, V.3    Runge, A.4    Zerial, M.5
  • 30
    • 84860141356 scopus 로고    scopus 로고
    • Rab20 regulates phagosome maturation in RAW264 macrophages during Fc gamma receptor-mediated phagocytosis
    • CrossRef PubMed
    • Egami, Y. and Araki, N. (2012) Rab20 regulates phagosome maturation in RAW264 macrophages during Fc gamma receptor-mediated phagocytosis. PLoS One 7, e35663 CrossRef PubMed
    • (2012) PLoS One , vol.7 , pp. e35663
    • Egami, Y.1    Araki, N.2
  • 31
    • 79952807443 scopus 로고    scopus 로고
    • Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes
    • CrossRef PubMed
    • Seto, S., Tsujimura, K. and Koide, Y. (2011) Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. Traffic 12, 407-420 CrossRef PubMed
    • (2011) Traffic , vol.12 , pp. 407-420
    • Seto, S.1    Tsujimura, K.2    Koide, Y.3
  • 32
    • 84899763957 scopus 로고    scopus 로고
    • Identification of an immune-regulated phagosomal Rab cascade in macrophages
    • CrossRef PubMed
    • Pei, G., Repnik, U., Griffiths, G. and Gutierrez, M. G. (2014) Identification of an immune-regulated phagosomal Rab cascade in macrophages. J. Cell. Sci. 127, 2071-2082 CrossRef PubMed
    • (2014) J. Cell. Sci. , vol.127 , pp. 2071-2082
    • Pei, G.1    Repnik, U.2    Griffiths, G.3    Gutierrez, M.G.4
  • 33
    • 46749156739 scopus 로고    scopus 로고
    • Large scale screening for novel rab effectors reveals unexpected broad Rab binding specificity
    • CrossRef PubMed
    • Fukuda, M., Kanno, E., Ishibashi, K. and Itoh, T. (2008) Large scale screening for novel rab effectors reveals unexpected broad Rab binding specificity. Mol. Cell Proteomics 7, 1031-1042 CrossRef PubMed
    • (2008) Mol. Cell Proteomics , vol.7 , pp. 1031-1042
    • Fukuda, M.1    Kanno, E.2    Ishibashi, K.3    Itoh, T.4
  • 34
    • 29644446699 scopus 로고    scopus 로고
    • Specific role for p85/p110beta in GTP-binding-protein-mediated activation of Akt
    • CrossRef PubMed
    • Kubo, H., Hazeki, K., Takasuga, S. and Hazeki, O. (2005) Specific role for p85/p110beta in GTP-binding-protein-mediated activation of Akt. Biochem. J. 392, 607-614 CrossRef PubMed
    • (2005) Biochem. J. , vol.392 , pp. 607-614
    • Kubo, H.1    Hazeki, K.2    Takasuga, S.3    Hazeki, O.4
  • 35
    • 42149110310 scopus 로고    scopus 로고
    • Critical roles of the p110 beta subtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264.7 cells
    • CrossRef PubMed
    • Tsukamoto, K., Hazeki, K., Hoshi, M., Nigorikawa, K., Inoue, N., Sasaki, T. and Hazeki, O. (2008) Critical roles of the p110 beta subtype of phosphoinositide 3-kinase in lipopolysaccharide-induced Akt activation and negative regulation of nitrite production in RAW 264.7 cells. J. Immunol. 180, 2054-2061 CrossRef PubMed
    • (2008) J. Immunol. , vol.180 , pp. 2054-2061
    • Tsukamoto, K.1    Hazeki, K.2    Hoshi, M.3    Nigorikawa, K.4    Inoue, N.5    Sasaki, T.6    Hazeki, O.7
  • 36
    • 0027933578 scopus 로고
    • Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling
    • PubMed
    • Ninomiya, N., Hazeki, K., Fukui, Y., Seya, T., Okada, T., Hazeki, O. and Ui, M. (1994) Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling. J. Biol. Chem. 269, 22732-22737 PubMed
    • (1994) J. Biol. Chem. , vol.269 , pp. 22732-22737
    • Ninomiya, N.1    Hazeki, K.2    Fukui, Y.3    Seya, T.4    Okada, T.5    Hazeki, O.6    Ui, M.7
  • 38
    • 81755184378 scopus 로고    scopus 로고
    • Structural basis of the myosin X PH1(N)-PH2-PH1(C) tandem as a specific and acute cellular PI(3,4, 5)P3 sensor
    • CrossRef PubMed
    • Lu, Q., Yu, J., Yan, J., Wei, Z. and Zhang, M. (2011) Structural basis of the myosin X PH1(N)-PH2-PH1(C) tandem as a specific and acute cellular PI(3,4,5)P3 sensor. Mol. Biol. Cell 22, 4268-4278 CrossRef PubMed
    • (2011) Mol. Biol. Cell , vol.22 , pp. 4268-4278
    • Lu, Q.1    Yu, J.2    Yan, J.3    Wei, Z.4    Zhang, M.5
  • 39
    • 0034604736 scopus 로고    scopus 로고
    • Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network
    • CrossRef PubMed
    • Kong, A. M., Speed, C. J., O'Malley, C. J., Layton, M. J., Meehan, T., Loveland, K. L., Cheema, S., Ooms, L. M. and Mitchell, C. A. (2000) Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network. J. Biol. Chem. 275, 24052-24064 CrossRef PubMed
    • (2000) J. Biol. Chem. , vol.275 , pp. 24052-24064
    • Kong, A.M.1    Speed, C.J.2    O'Malley, C.J.3    Layton, M.J.4    Meehan, T.5    Loveland, K.L.6    Cheema, S.7    Ooms, L.M.8    Mitchell, C.A.9
  • 40
    • 0034733569 scopus 로고    scopus 로고
    • The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase
    • CrossRef PubMed
    • Kisseleva, M. V., Wilson, M. P. and Majerus, P. W. (2000) The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase. J. Biol. Chem. 275, 20110-20116 CrossRef PubMed
    • (2000) J. Biol. Chem. , vol.275 , pp. 20110-20116
    • Kisseleva, M.V.1    Wilson, M.P.2    Majerus, P.W.3
  • 41
    • 0033595149 scopus 로고    scopus 로고
    • Pharbin, a novel inositol polyphosphate 5-phosphatase, induces dendritic appearances in fibroblasts
    • CrossRef PubMed
    • Asano, T., Mochizuki, Y., Matsumoto, K., Takenawa, T. and Endo, T. (1999) Pharbin, a novel inositol polyphosphate 5-phosphatase, induces dendritic appearances in fibroblasts. Biochem. Biophys. Res. Commun. 261, 188-195 CrossRef PubMed
    • (1999) Biochem. Biophys. Res. Commun. , vol.261 , pp. 188-195
    • Asano, T.1    Mochizuki, Y.2    Matsumoto, K.3    Takenawa, T.4    Endo, T.5
  • 42
    • 84871685272 scopus 로고    scopus 로고
    • Spatiotemporal localization of Rab20 in live RAW264 macrophages during macropinocytosis
    • CrossRef PubMed
    • Egami, Y. and Araki, N. (2012) Spatiotemporal localization of Rab20 in live RAW264 macrophages during macropinocytosis. Acta Histochem. Cytochem. 45, 317-323 CrossRef PubMed
    • (2012) Acta Histochem. Cytochem. , vol.45 , pp. 317-323
    • Egami, Y.1    Araki, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.