Behavioral phenotyping of Parkin-deficient mice: Looking for early preclinical features of Parkinson's disease

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Rial, Daniel ^a,b   Castro, Adalberto A ^a   Machado, Nuno ^b   Garҫão, Pedro ^b   Gonҫalves, Francisco Q ^b   Silva, Henrique B ^b   Tomé, Ângelo R ^b,d   Köfalvi, Attila ^b   Corti, Olga ^c   Raisman Vozari, Rita ^c   Cunha, Rodrigo A ^b,e   Prediger, Rui D ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; DOPAMINE; GLUTAMIC ACID; GLUTAMINE; PARKIN; UBIQUITIN PROTEIN LIGASE;

AMNESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CLINICAL FEATURE; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; DOPAMINE RELEASE; ELEVATED PLUS MAZE TEST; EMOTION; EXON; EXPLORATORY BEHAVIOR TEST; FORCED SWIM TEST; GENE; GENE DELETION; GRIP STRENGTH; HABITUATION; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MOUSE; NERVE CELL PLASTICITY; NERVE ENDING; NONHUMAN; OLFACTORY DISCRIMINATION; OLFACTORY SYSTEM; OPEN FIELD TEST; PARKIN GENE; PARKINSON DISEASE; PHENOTYPE; POLE TEST; ROTAROD TEST; SPATIAL MEMORY; TAIL SUSPENSION TEST; Y-MAZE TEST; ANIMAL; DEFICIENCY; DISEASE MODEL; GENETICS; HOMOZYGOTE; KNOCKOUT MOUSE; LOCOMOTION; MEMORY; METABOLISM; MOTOR ACTIVITY; PATHOPHYSIOLOGY;

MUS;

ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DOPAMINE; GENE DELETION; HIPPOCAMPUS; HOMOZYGOTE; LOCOMOTION; LONG-TERM POTENTIATION; MALE; MEMORY; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NERVE ENDINGS; PARKINSON DISEASE; PHENOTYPE; UBIQUITIN-PROTEIN LIGASES;

EID: 84915758165     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114216     Document Type: Article

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