Analytical validation considerations of multiplex mass-spectrometry-based proteomic platforms for measuring protein biomarkers

Journal of Proteome Research

Volumn 13, Issue 12, 2014, Pages 5325-5332

  Boja, Emily S ^a   Fehniger, Thomas E ^b,c   Baker, Mark S ^d   Marko Varga, György ^b,c,e   Rodriguez, Henry ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b LUND UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d MACQUARIE UNIVERSITY   (Australia)

^e TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

immunoassays; MRM MS; multiplex proteomics assays; protein biomarker; quantitative targeted proteomics

Indexed keywords

BIOLOGICAL MARKER; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA; PROTEIN; RECOMBINANT PROTEIN; RNA 16S; PROTEOME; TUMOR MARKER;

AMINO ACID SEQUENCE; ARTICLE; CHEMILUMINESCENCE IMMUNOASSAY; DNA MICROARRAY; FOOD AND DRUG ADMINISTRATION; GENE SEQUENCE; GENOMICS; HEALTH CARE SYSTEM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; PHENOTYPE; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; BIOLOGY; DEVICES; MEDICAL RESEARCH; METABOLISM; NEOPLASMS; PROCEDURES; REPRODUCIBILITY; STANDARDS; TRENDS;

BIOMARKERS, TUMOR; BIOMEDICAL RESEARCH; COMPUTATIONAL BIOLOGY; HUMANS; MASS SPECTROMETRY; NEOPLASMS; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS;

EID: 84915751027     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr500753r     Document Type: Article

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