Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Wang, Yue J ^a   McAllister, Florencia ^a   Bailey, Jennifer M ^a   Scott, Sherri Gae ^a   Hendley, Audrey M ^a   Leach, Steven D ^a,b   Ghosh, Bidyut ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; DEAD BOX PROTEIN; DICER1 PROTEIN, MOUSE; KRAS2 PROTEIN, MOUSE; PROTEIN P21; RIBONUCLEASE III;

ACINAR CELL; ACINAR TO DUCTAL METAPLASIA; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL LEVEL; CELL POLARITY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE ACTIVATION; GENE DELETION; GENE DOSAGE; HISTOPATHOLOGY; IN VITRO STUDY; METAPLASIA; MOUSE; NONHUMAN; ONCOGENE K RAS; PANCREAS ADENOMA; PHENOTYPIC PLASTICITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANIMAL; CYTOLOGY; DEFICIENCY; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; METABOLISM; PANCREAS; PANCREAS TUMOR; PHYSIOLOGY;

ACINAR CELLS; ANIMALS; CELL POLARITY; DEAD-BOX RNA HELICASES; EPITHELIAL-MESENCHYMAL TRANSITION; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; MICE; PANCREAS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS P21(RAS); RIBONUCLEASE III;

EID: 84915750650     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113127     Document Type: Article

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