Serum metabolomic profiling in acute alcoholic hepatitis identifies multiple dysregulated pathways

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Rachakonda, Vikrant ^a   Gabbert, Charles ^a   Raina, Amit ^a,d   Bell, Lauren N ^b   Cooper, Sara ^c   Malik, Shahid ^a   Behari, Jaideep ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b METABOLON INC   (United States)

^c HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^d EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLADENOSINE; 3 HYDROXY 2 METHYLPROPIONIC ACID; ACETYLCARNITINE; ALANINE AMINOTRANSFERASE; ALBUMIN; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CREATININE; DEOXYCHOLIC ACID; DOCOSAPENTAENOIC ACID; FATTY ACID; GLUCOSE; GLUCURONIC ACID; GLUTATHIONE; GLYCEROPHOSPHORYLCHOLINE; GLYCODEOXYCHOLIC ACID; HEMOGLOBIN; ICOSAPENTAENOIC ACID; KETONE; MONOACYLGLYCEROL; OMEGA 3 FATTY ACID; PENTOSE PHOSPHATE; PIPECOLIC ACID; PROPYLENE GLYCOL; RIBITOL; TRIACYLGLYCEROL; TRICARBOXYLIC ACID; XYLITOL; BILE ACID; BIOLOGICAL MARKER; XENOBIOTIC AGENT;

ACCURACY; ADULT; ALCOHOL LIVER DISEASE; ARTICLE; BLOOD SAMPLING; CASE CONTROL STUDY; CELL MEMBRANE; CITRIC ACID CYCLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DYSBIOSIS; ENERGY BALANCE; FATTY ACID OXIDATION; FEMALE; FOLLOW UP; GLUCOSE INTAKE; HEPATITIS B; HEPATITIS C; HUMAN; INTERNATIONAL NORMALIZED RATIO; LEUKOCYTE COUNT; LIPOLYSIS; LIVER CIRRHOSIS; LOGISTIC REGRESSION ANALYSIS; MALE; METABOLOMICS; MIDDLE AGED; MODEL FOR END STAGE LIVER DISEASE SCORE; OUTPATIENT; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PROGNOSIS; PROSPECTIVE STUDY; PROTEIN METABOLISM; RANDOM FOREST; SURVIVAL RATE; THROMBOCYTE COUNT; ACUTE DISEASE; ADIPOSE TISSUE; BLOOD; CLUSTER ANALYSIS; ENERGY METABOLISM; INFLAMMATION; LIPID METABOLISM; METABOLISM; METABOLOME; MITOCHONDRION; OXIDATION REDUCTION REACTION; PATHOLOGY; PROCEDURES; STATISTICAL MODEL;

ACUTE DISEASE; ADIPOSE TISSUE; BILE ACIDS AND SALTS; BIOMARKERS; CASE-CONTROL STUDIES; CELL MEMBRANE; CLUSTER ANALYSIS; DYSBIOSIS; ENERGY METABOLISM; FATTY ACIDS; FEMALE; GLUCOSE; HEPATITIS, ALCOHOLIC; HUMANS; INFLAMMATION; LIPID METABOLISM; LOGISTIC MODELS; MALE; METABOLIC NETWORKS AND PATHWAYS; METABOLOME; METABOLOMICS; MIDDLE AGED; MITOCHONDRIA; OXIDATION-REDUCTION; PRINCIPAL COMPONENT ANALYSIS; XENOBIOTICS;

EID: 84914693446     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113860     Document Type: Article

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