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Volumn 34, Issue 10, 2014, Pages 2224-2231

Thin-cap fibroatheroma rupture is associated with a fine interplay of shear and wall stress

Author keywords

Atherosclerosis; Biomechanical phenomena; Cellular mechanotransduction; Genomics

Indexed keywords

ANGIOCARDIOGRAPHY; ARTERIAL STIFFNESS; ARTERIAL WALL THICKNESS; ATHEROSCLEROTIC PLAQUE; BIOMECHANICS; BLOOD FLOW; BLOOD VESSEL RUPTURE; CELL FUNCTION; CONCENTRATION PROCESS; DISEASE ASSOCIATION; ENDOTHELIUM CELL; FINITE ELEMENT ANALYSIS; HEMODYNAMICS; HISTOPATHOLOGY; HUMAN; INFLAMMATION; MECHANICS; MECHANOTRANSDUCTION; MOLECULAR EVOLUTION; MOLECULAR IMAGING; REGULATORY MECHANISM; REVIEW; SHEAR STRESS; THIN CAP FIBROATHEROMA RUPTURE; WALL STRESS; ANIMAL; ARTERY; ATHEROSCLEROSIS; COMPLICATION; DISEASE COURSE; FIBROSIS; MECHANICAL STRESS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RISK FACTOR; RUPTURE;

EID: 84914168061     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303426     Document Type: Review
Times cited : (48)

References (58)
  • 2
    • 84883878365 scopus 로고    scopus 로고
    • Mechanisms of acute coronary syndromes
    • Libby P. Mechanisms of acute coronary syndromes. N Engl J Med. 2013;369:883-884.
    • (2013) N Engl J Med , vol.369 , pp. 883-884
    • Libby, P.1
  • 3
    • 0026585495 scopus 로고
    • Anatomic features in victims of sudden coronary death. Coronary artery pathology
    • Davies MJ. Anatomic features in victims of sudden coronary death. Coronary artery pathology. Circulation. 1992;85(1 Suppl):I19-I24.
    • (1992) Circulation , vol.85 , Issue.1 , pp. I19-I24
    • Davies, M.J.1
  • 4
    • 0038201864 scopus 로고    scopus 로고
    • Pathology of the thin-cap fibroatheroma: A type of vulnerable plaque
    • Virmani R, Burke AP, Kolodgie FD, Farb A. Pathology of the thin-cap fibroatheroma: a type of vulnerable plaque. J Interv Cardiol. 2003;16:267-272.
    • (2003) J Interv Cardiol , vol.16 , pp. 267-272
    • Virmani, R.1    Burke, A.P.2    Kolodgie, F.D.3    Farb, A.4
  • 7
    • 49349089984 scopus 로고    scopus 로고
    • Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris. A 3-vessel optical coherence tomography study
    • Fujii K, Masutani M, Okumura T, Kawasaki D, Akagami T, Ezumi A, Sakoda T, Masuyama T, Ohyanagi M. Frequency and predictor of coronary thin-cap fibroatheroma in patients with acute myocardial infarction and stable angina pectoris. A 3-vessel optical coherence tomography study. J Am Coll Cardiol. 2008;52:787-788.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 787-788
    • Fujii, K.1    Masutani, M.2    Okumura, T.3    Kawasaki, D.4    Akagami, T.5    Ezumi, A.6    Sakoda, T.7    Masuyama, T.8    Ohyanagi, M.9
  • 12
    • 39149116773 scopus 로고    scopus 로고
    • Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels
    • Humphrey JD. Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels. Cell Biochem Biophys. 2008;50:53-78.
    • (2008) Cell Biochem Biophys , vol.50 , pp. 53-78
    • Humphrey, J.D.1
  • 14
    • 3042739820 scopus 로고    scopus 로고
    • A constrained mixture model for arterial adaptations to a sustained step change in blood flow
    • Humphrey JD, Rajagopal KR. A constrained mixture model for arterial adaptations to a sustained step change in blood flow. Biomech Model Mechanobiol. 2003;2:109-126.
    • (2003) Biomech Model Mechanobiol , vol.2 , pp. 109-126
    • Humphrey, J.D.1    Rajagopal, K.R.2
  • 15
    • 0027359717 scopus 로고
    • Five-year angiographic follow-up of factors associated with progression of coronary artery disease in the coronary artery surgery study (cass). Cass participating investigators and staff
    • Alderman EL, Corley SD, Fisher LD, Chaitman BR, Faxon DP, Foster ED, Killip T, Sosa JA, Bourassa MG. Five-year angiographic follow-up of factors associated with progression of coronary artery disease in the Coronary Artery Surgery Study (CASS). CASS Participating Investigators and Staff. J Am Coll Cardiol. 1993;22:1141-1154.
    • (1993) J Am Coll Cardiol , vol.22 , pp. 1141-1154
    • Alderman, E.L.1    Corley, S.D.2    Fisher, L.D.3    Chaitman, B.R.4    Faxon, D.P.5    Foster, E.D.6    Killip, T.7    Sosa, J.A.8    Bourassa, M.G.9
  • 17
    • 0023722916 scopus 로고
    • Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?
    • Little WC, Constantinescu M, Applegate RJ, Kutcher MA, Burrows MT, Kahl FR, Santamore WP. Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? Circulation. 1988;78(5, Part 1):1157-1166.
    • (1988) Circulation , vol.78 , Issue.5 , pp. 1157-1166
    • Little, W.C.1    Constantinescu, M.2    Applegate, R.J.3    Kutcher, M.A.4    Burrows, M.T.5    Kahl, F.R.6    Santamore, W.P.7
  • 18
    • 0026524594 scopus 로고
    • Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography
    • Giroud D, Li JM, Urban P, Meier B, Rutishauer W. Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography. Am J Cardiol. 1992;69:729-732.
    • (1992) Am J Cardiol , vol.69 , pp. 729-732
    • Giroud, D.1    Li, J.M.2    Urban, P.3    Meier, B.4    Rutishauer, W.5
  • 21
    • 0026450676 scopus 로고
    • Why do plaques rupture?
    • Falk E. Why do plaques rupture? Circulation. 1992;86(6 Suppl):III30-III42.
    • (1992) Circulation , vol.86 , Issue.6 , pp. III30-III42
    • Falk, E.1
  • 22
    • 0024330373 scopus 로고
    • Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques
    • Richardson PD, Davies MJ, Born GV. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet. 1989;2:941-944.
    • (1989) Lancet , vol.2 , pp. 941-944
    • Richardson, P.D.1    Davies, M.J.2    Born, G.V.3
  • 23
    • 0026787340 scopus 로고
    • Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels
    • Loree HM, Kamm RD, Stringfellow RG, Lee RT. Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels. Circ Res. 1992;71:850-858.
    • (1992) Circ Res , vol.71 , pp. 850-858
    • Loree, H.M.1    Kamm, R.D.2    Stringfellow, R.G.3    Lee, R.T.4
  • 24
    • 0027516690 scopus 로고
    • Distribution of circumferential stress in ruptured and stable atherosclerotic lesions. A structural analysis with histopathological correlation
    • Cheng GC, Loree HM, Kamm RD, Fishbein MC, Lee RT. Distribution of circumferential stress in ruptured and stable atherosclerotic lesions. A structural analysis with histopathological correlation. Circulation. 1993;87:1179-1187.
    • (1993) Circulation , vol.87 , pp. 1179-1187
    • Cheng, G.C.1    Loree, H.M.2    Kamm, R.D.3    Fishbein, M.C.4    Lee, R.T.5
  • 25
    • 33947575785 scopus 로고    scopus 로고
    • Structural analysis and magnetic resonance imaging predict plaque vulnerability: A study comparing symptomatic and asymptomatic individuals
    • Li ZY, Howarth SP, Tang T, Graves MJ, U-King-Im J, Trivedi RA, Kirkpatrick PJ, Gillard JH. Structural analysis and magnetic resonance imaging predict plaque vulnerability: a study comparing symptomatic and asymptomatic individuals. J Vasc Surg. 2007;45:768-775.
    • (2007) J Vasc Surg , vol.45 , pp. 768-775
    • Li, Z.Y.1    Howarth, S.P.2    Tang, T.3    Graves, M.J.4    U-King-Im, J.5    Trivedi, R.A.6    Kirkpatrick, P.J.7    Gillard, J.H.8
  • 26
    • 34548818769 scopus 로고    scopus 로고
    • Identifying vulnerable carotid plaques in vivo using high resolution magnetic resonance imaging-based finite element analysis
    • Trivedi RA, Li ZY, U-King-Im J, Graves MJ, Kirkpatrick PJ, Gillard JH. Identifying vulnerable carotid plaques in vivo using high resolution magnetic resonance imaging-based finite element analysis. J Neurosurg. 2007;107:536-542.
    • (2007) J Neurosurg , vol.107 , pp. 536-542
    • Trivedi, R.A.1    Li, Z.Y.2    U-King-Im, J.3    Graves, M.J.4    Kirkpatrick, P.J.5    Gillard, J.H.6
  • 27
    • 70349661679 scopus 로고    scopus 로고
    • Sites of rupture in human atherosclerotic carotid plaques are associated with high structural stresses: An in vivo mri-based 3d fluid-structure interaction study
    • Tang D, Teng Z, Canton G, Yang C, Ferguson M, Huang X, Zheng J, Woodard PK, Yuan C. Sites of rupture in human atherosclerotic carotid plaques are associated with high structural stresses: an in vivo MRI-based 3D fluid-structure interaction study. Stroke. 2009;40:3258-3263.
    • (2009) Stroke , vol.40 , pp. 3258-3263
    • Tang, D.1    Teng, Z.2    Canton, G.3    Yang, C.4    Ferguson, M.5    Huang, X.6    Zheng, J.7    Woodard, P.K.8    Yuan, C.9
  • 28
    • 77954951042 scopus 로고    scopus 로고
    • Stress analysis of carotid atheroma in a transient ischaemic attack patient using the mribased fluid-structure interaction method
    • Gao H, Long Q, Sadat U, Graves M, Gillard JH, Li ZY. Stress analysis of carotid atheroma in a transient ischaemic attack patient using the MRIbased fluid-structure interaction method. Br J Radiol. 2009;82 Spec No 1:S46-S54.
    • (2009) Br J Radiol , vol.82 , pp. S46-S54
    • Gao, H.1    Long, Q.2    Sadat, U.3    Graves, M.4    Gillard, J.H.5    Li, Z.Y.6
  • 29
    • 77955175980 scopus 로고    scopus 로고
    • Carotid atheroma rupture observed in vivo and fsi-predicted stress distribution based on pre-rupture imaging
    • Leach JR, Rayz VL, Soares B, Wintermark M, Mofrad MR, Saloner D. Carotid atheroma rupture observed in vivo and FSI-predicted stress distribution based on pre-rupture imaging. Ann Biomed Eng. 2010;38:2748-2765.
    • (2010) Ann Biomed Eng , vol.38 , pp. 2748-2765
    • Leach, J.R.1    Rayz, V.L.2    Soares, B.3    Wintermark, M.4    Mofrad, M.R.5    Saloner, D.6
  • 30
    • 84870902110 scopus 로고    scopus 로고
    • Relation between plaque type, plaque thickness, blood shear stress, and plaque stress in coronary arteries assessed by x-ray angiography and intravascular ultrasound
    • Balocco S, Gatta C, Alberti M, Carrillo X, Rigla J, Radeva P. Relation between plaque type, plaque thickness, blood shear stress, and plaque stress in coronary arteries assessed by X-ray angiography and intravascular ultrasound. Med Phys. 2012;39:7430-7445.
    • (2012) Med Phys , vol.39 , pp. 7430-7445
    • Balocco, S.1    Gatta, C.2    Alberti, M.3    Carrillo, X.4    Rigla, J.5    Radeva, P.6
  • 31
    • 84897935190 scopus 로고    scopus 로고
    • Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: An ivus-based fluid-structure interaction multi-patient study
    • Fan R, Tang D, Yang C, Zheng J, Bach R, Wang L, Muccigrosso D, Billiar K, Zhu J, Ma G, Maehara A, Mintz GS. Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: an IVUS-based fluid-structure interaction multi-patient study. Biomed Eng Online. 2014;13:32.
    • (2014) Biomed Eng Online , vol.13 , pp. 32
    • Fan, R.1    Tang, D.2    Yang, C.3    Zheng, J.4    Bach, R.5    Wang, L.6    Muccigrosso, D.7    Billiar, K.8    Zhu, J.9    Ma, G.10    Maehara, A.11    Mintz, G.S.12
  • 32
    • 84873356541 scopus 로고    scopus 로고
    • Biomechanical factors in coronary vulnerable plaque risk of rupture: Intravascular ultrasound-based patient-specific fluid-structure interaction studies
    • Liang X, Xenos M, Alemu Y, Rambhia SH, Lavi I, Kornowski R, Gruberg L, Fuchs S, Einav S, Bluestein D. Biomechanical factors in coronary vulnerable plaque risk of rupture: intravascular ultrasound-based patient-specific fluid-structure interaction studies. Coron Artery Dis. 2013;24:75-87.
    • (2013) Coron Artery Dis , vol.24 , pp. 75-87
    • Liang, X.1    Xenos, M.2    Alemu, Y.3    Rambhia, S.H.4    Lavi, I.5    Kornowski, R.6    Gruberg, L.7    Fuchs, S.8    Einav, S.9    Bluestein, D.10
  • 34
    • 0025896776 scopus 로고
    • Structuredependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques
    • Lee RT, Grodzinsky AJ, Frank EH, Kamm RD, Schoen FJ. Structuredependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques. Circulation. 1991;83:1764-1770.
    • (1991) Circulation , vol.83 , pp. 1764-1770
    • Lee, R.T.1    Grodzinsky, A.J.2    Frank, E.H.3    Kamm, R.D.4    Schoen, F.J.5
  • 35
    • 70450184150 scopus 로고    scopus 로고
    • Nanomechanical properties of calcification, fibrous tissue, and hematoma from atherosclerotic plaques
    • Ebenstein DM, Coughlin D, Chapman J, Li C, Pruitt LA. Nanomechanical properties of calcification, fibrous tissue, and hematoma from atherosclerotic plaques. J Biomed Mater Res A. 2009;91:1028-1037.
    • (2009) J Biomed Mater Res A , vol.91 , pp. 1028-1037
    • Ebenstein, D.M.1    Coughlin, D.2    Chapman, J.3    Li, C.4    Pruitt, L.A.5
  • 36
    • 79952453592 scopus 로고    scopus 로고
    • Mapping elasticity moduli of atherosclerotic plaque in situ via atomic force microscopy
    • Tracqui P, Broisat A, Toczek J, Mesnier N, Ohayon J, Riou L. Mapping elasticity moduli of atherosclerotic plaque in situ via atomic force microscopy. J Struct Biol. 2011;174:115-123.
    • (2011) J Struct Biol , vol.174 , pp. 115-123
    • Tracqui, P.1    Broisat, A.2    Toczek, J.3    Mesnier, N.4    Ohayon, J.5    Riou, L.6
  • 38
    • 0034019601 scopus 로고    scopus 로고
    • Lessons from sudden coronary death: A comprehensive morphological classification scheme for atherosclerotic lesions
    • Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 2000;20:1262-1275.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1262-1275
    • Virmani, R.1    Kolodgie, F.D.2    Burke, A.P.3    Farb, A.4    Schwartz, S.M.5
  • 41
    • 33845944188 scopus 로고    scopus 로고
    • Multiaxial mechanical characteristics of carotid plaque: Analysis by multiarray echotracking system
    • Paini A, Boutouyrie P, Calvet D, Zidi M, Agabiti-Rosei E, Laurent S. Multiaxial mechanical characteristics of carotid plaque: analysis by multiarray echotracking system. Stroke. 2007;38:117-123.
    • (2007) Stroke , vol.38 , pp. 117-123
    • Paini, A.1    Boutouyrie, P.2    Calvet, D.3    Zidi, M.4    Agabiti-Rosei, E.5    Laurent, S.6
  • 42
    • 79955939930 scopus 로고    scopus 로고
    • Mechanical and structural characteristics of carotid plaques by combined analysis with echotracking system and mr imaging
    • Beaussier H, Naggara O, Calvet D, et al. Mechanical and structural characteristics of carotid plaques by combined analysis with echotracking system and MR imaging. J Am Coll Cardiol Cardiovasc Imaging. 2011;4:468-477.
    • (2011) J Am Coll Cardiol Cardiovasc Imaging , vol.4 , pp. 468-477
    • Beaussier, H.1    Naggara, O.2    Calvet, D.3
  • 43
    • 58049213790 scopus 로고    scopus 로고
    • Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology
    • Davies PF. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovasc Med. 2009;6:16-26.
    • (2009) Nat Clin Pract Cardiovasc Med , vol.6 , pp. 16-26
    • Davies, P.F.1
  • 44
    • 58049211966 scopus 로고    scopus 로고
    • Mechanotransduction at a distance: Mechanically coupling the extracellular matrix with the nucleus
    • Wang N, Tytell JD, Ingber DE. Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol. 2009;10:75-82.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 75-82
    • Wang, N.1    Tytell, J.D.2    Ingber, D.E.3
  • 45
    • 0036843301 scopus 로고    scopus 로고
    • Role of integrins in endothelial mechanosensing of shear stress
    • Shyy JY, Chien S. Role of integrins in endothelial mechanosensing of shear stress. Circ Res. 2002;91:769-775.
    • (2002) Circ Res , vol.91 , pp. 769-775
    • Shyy, J.Y.1    Chien, S.2
  • 46
    • 0034771241 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cyclic strain-induced endothelin- 1 gene expression via ras/raf/extracellular signal-regulated kinase pathway in endothelial cells
    • Cheng TH, Shih NL, Chen SY, Loh SH, Cheng PY, Tsai CS, Liu SH, Wang DL, Chen JJ. Reactive oxygen species mediate cyclic strain-induced endothelin- 1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells. J Mol Cell Cardiol. 2001;33:1805-1814.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 1805-1814
    • Cheng, T.H.1    Shih, N.L.2    Chen, S.Y.3    Loh, S.H.4    Cheng, P.Y.5    Tsai, C.S.6    Liu, S.H.7    Wang, D.L.8    Chen, J.J.9
  • 47
    • 0029978375 scopus 로고    scopus 로고
    • Cyclical strain increases monocyte chemotactic protein-1 secretion in human endothelial cells
    • Wung BS, Cheng JJ, Chao YJ, Lin J, Shyy YJ, Wang DL. Cyclical strain increases monocyte chemotactic protein-1 secretion in human endothelial cells. Am J Physiol. 1996;270(4, Part 2):H1462-H1468.
    • (1996) Am J Physiol , vol.270 , Issue.4 , pp. H1462-H1468
    • Wung, B.S.1    Cheng, J.J.2    Chao, Y.J.3    Lin, J.4    Shyy, Y.J.5    Wang, D.L.6
  • 48
    • 0031799830 scopus 로고    scopus 로고
    • Cyclic stretch upregulates production of interleukin-8 and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in human endothelial cells
    • Okada M, Matsumori A, Ono K, Furukawa Y, Shioi T, Iwasaki A, Matsushima K, Sasayama S. Cyclic stretch upregulates production of interleukin-8 and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in human endothelial cells. Arterioscler Thromb Vasc Biol. 1998;18:894-901.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 894-901
    • Okada, M.1    Matsumori, A.2    Ono, K.3    Furukawa, Y.4    Shioi, T.5    Iwasaki, A.6    Matsushima, K.7    Sasayama, S.8
  • 49
    • 36048976652 scopus 로고    scopus 로고
    • Cyclic stretch controls the expression of cd40 in endothelial cells by changing their transforming growth factorbeta1 response
    • Korff T, Aufgebauer K, Hecker M. Cyclic stretch controls the expression of CD40 in endothelial cells by changing their transforming growth factorbeta1 response. Circulation. 2007;116:2288-2297.
    • (2007) Circulation , vol.116 , pp. 2288-2297
    • Korff, T.1    Aufgebauer, K.2    Hecker, M.3
  • 51
    • 0032754564 scopus 로고    scopus 로고
    • Transmural pressure induces matrixdegrading activity in porcine arteries ex vivo
    • Chesler NC, Ku DN, Galis ZS. Transmural pressure induces matrixdegrading activity in porcine arteries ex vivo. Am J Physiol. 1999;277(5, Part 2):H2002-H2009.
    • (1999) Am J Physiol , vol.277 , Issue.5 , pp. H2002-H2009
    • Chesler, N.C.1    Ku, D.N.2    Galis, Z.S.3
  • 52
    • 0038718531 scopus 로고    scopus 로고
    • Mechanical stretch enhances mrna expression and proenzyme release of matrix metalloproteinase-2 (mmp-2) via nad(p)h oxidase-derived reactive oxygen species
    • Grote K, Flach I, Luchtefeld M, Akin E, Holland SM, Drexler H, Schieffer B. Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species. Circ Res. 2003;92:e80-e86.
    • (2003) Circ Res , vol.92 , pp. e80-e86
    • Grote, K.1    Flach, I.2    Luchtefeld, M.3    Akin, E.4    Holland, S.M.5    Drexler, H.6    Schieffer, B.7
  • 53
    • 84881324368 scopus 로고    scopus 로고
    • Mechanical stretch increases mmp-2 production in vascular smooth muscle cells via activation of pdgfr-β/akt signaling pathway
    • Seo KW, Lee SJ, Kim YH, Bae JU, Park SY, Bae SS, Kim CD. Mechanical stretch increases MMP-2 production in vascular smooth muscle cells via activation of PDGFR-β/Akt signaling pathway. PLoS One. 2013;8:e70437.
    • (2013) PLoS One , vol.8
    • Seo, K.W.1    Lee, S.J.2    Kim, Y.H.3    Bae, J.U.4    Park, S.Y.5    Bae, S.S.6    Kim, C.D.7
  • 54
    • 0029835633 scopus 로고    scopus 로고
    • Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture
    • Lee RT, Schoen FJ, Loree HM, Lark MW, Libby P. Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture. Arterioscler Thromb Vasc Biol. 1996;16:1070-1073.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1070-1073
    • Lee, R.T.1    Schoen, F.J.2    Loree, H.M.3    Lark, M.W.4    Libby, P.5
  • 55
    • 0345465669 scopus 로고    scopus 로고
    • Evidence for increased collagenolysis by interstitial collagenases- 1 and -3 in vulnerable human atheromatous plaques
    • Sukhova GK, Schönbeck U, Rabkin E, Schoen FJ, Poole AR, Billinghurst RC, Libby P. Evidence for increased collagenolysis by interstitial collagenases- 1 and -3 in vulnerable human atheromatous plaques. Circulation. 1999;99:2503-2509.
    • (1999) Circulation , vol.99 , pp. 2503-2509
    • Sukhova, G.K.1    Schönbeck, U.2    Rabkin, E.3    Schoen, F.J.4    Poole, A.R.5    Billinghurst, R.C.6    Libby, P.7
  • 56
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest. 1994;94:2493-2503.
    • (1994) J Clin Invest , vol.94 , pp. 2493-2503
    • Galis, Z.S.1    Sukhova, G.K.2    Lark, M.W.3    Libby, P.4
  • 57
    • 84868111953 scopus 로고    scopus 로고
    • Mechanosensitive mechanisms in transcriptional regulation
    • Mammoto A, Mammoto T, Ingber DE. Mechanosensitive mechanisms in transcriptional regulation. J Cell Sci. 2012;125(Part 13):3061-3073.
    • (2012) J Cell Sci , vol.125 , pp. 3061-3073
    • Mammoto, A.1    Mammoto, T.2    Ingber, D.E.3
  • 58
    • 67849101004 scopus 로고    scopus 로고
    • Mechanosensitive trp channels in cardiovascular pathophysiology
    • Inoue R, Jian Z, Kawarabayashi Y. Mechanosensitive TRP channels in cardiovascular pathophysiology. Pharmacol Ther. 2009;123:371-385.
    • (2009) Pharmacol Ther , vol.123 , pp. 371-385
    • Inoue, R.1    Jian, Z.2    Kawarabayashi, Y.3


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