The protective effect of curcumin against the 19-kDa Mycobacterium tuberculosis protein-induced inflammation and apoptosis in human macrophages

Molecular Medicine Reports

Volumn 10, Issue 6, 2014, Pages 3261-3267

  Li, Mingying ^a   Wu, Zhenxuan ^a   Niu, Wenyi ^a   Wan, Yonggan ^a   Zhang, Ligong ^a   Shi, Guangcan ^a   Xi, Xiu'E ^a  

^a XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; c Jun N terminal kinase; Curcumin; Macrophages; Mycobacterium tuberculosis 19 kDa lipoprotein

Indexed keywords

MYCOBACTERIUM TUBERCULOSIS;

19 KDA ANTIGEN, MYCOBACTERIUM; BACTERIAL PROTEIN; CURCUMIN; DEATH RECEPTOR; INTERLEUKIN 6; LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; CELL LINE; DRUG EFFECTS; HUMAN; INFLAMMATION; MACROPHAGE; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUBERCULOSIS;

APOPTOSIS; BACTERIAL PROTEINS; CELL LINE; CURCUMIN; HUMANS; INFLAMMATION; INTERLEUKIN-6; LIPOPROTEINS; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MYCOBACTERIUM TUBERCULOSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84914162396     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2615     Document Type: Article

References (34)

1. Dye C, Scheele S, Dolin P, Pathania V and Raviglione MC: Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project. JAMA 282: 677-686, 1999.
2. Bhatt K and Salgame P: Host innate immune response to Mycobacterium tuberculosis. J Clin Immunol 27: 347-362, 2007.
3. Akira S, Uematsu S and Takeuchi O: Pathogen recognition and innate immunity. Cell 124: 783-801, 2006.
4. Underhill DM, Ozinsky A, Smith KD and Aderem A: Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc Natl Acad Sci USA 96: 14459-14463, 1999.
5. Quesniaux V, Fremond C, Jacobs M, et al: Toll-like receptor pathways in the immune responses to mycobacteria. Microbes Infect 6: 946-959, 2004.
6. Holscher C, Reiling N, Schaible UE, et al: Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9. Eur J Immunol 38: 680-694, 2008.
7. Cole ST, Brosch R, Parkhill J, et al: Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544, 1998.
8. Boom WH, Husson RN, Young RA, David JR and Piessens WF: In vivo and in vitro characterization of murine T-cell clones reactive to Mycobacterium tuberculosis. Infect Immun 55: 2223-2229, 1987.
9. Brightbill HD, Libraty DH, Krutzik SR, et al: Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 285: 732-736, 1999.
10. Diaz-Silvestre H, Espinosa-Cueto P, Sanchez-Gonzalez A, et al: The 19-kDa antigen of Mycobacterium tuberculosis is a major adhesin that binds the mannose receptor of THP-1 monocytic cells and promotes phagocytosis of mycobacteria. Microb Pathog 39: 97-107, 2005.
11. Sanchez A, Espinosa P, Garcia T and Mancilla R: The 19 kDa Mycobacterium tuberculosis lipoprotein (LpqH) induces macrophage apoptosis through extrinsic and intrinsic pathways: a role for the mitochondrial apoptosis-inducing factor. Clin Dev Immunol 2012: 950503, 2012.
12. Kuo ML, Huang TS and Lin JK: Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells. Biochim Biophys Acta 1317: 95-100, 1996.
13. Goel A, Kunnumakkara AB and Aggarwal BB: Curcumin as 'Curecumin': from kitchen to clinic. Biochem Pharmacol 75: 787-809, 2008.
14. Marathe SA, Dasgupta I, Gnanadhas DP and Chakravortty D: Multifaceted roles of curcumin: two sides of a coin! Expert Opin Biol Ther 11: 1485-1499, 2011.
15. Bukhari SN, Franzblau SG, Jantan I and Jasamai M: Current prospects of synthetic curcumin analogs and chalcone derivatives against Mycobacterium tuberculosis. Med Chem 9: 897-903, 2013.
16. Kawamori T, Lubet R, Steele VE, et al: Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res 59: 597-601, 1999.
17. Lu YP, Chang RL, Lou YR, et al: Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis. Carcinogenesis 15: 2363-2370, 1994.
18. Azuine MA and Bhide SV: Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice. Nutr Cancer 17: 77-83, 1992.
19. Shuto T, Ono T, Ohira Y, et al: Curcumin decreases toll-like receptor-2 gene expression and function in human monocytes and neutrophils. Biochem Biophys Res Commun 398: 647-652, 2010.
20. Schlesinger LS, Bellinger-kawahara CG, Payne NR and Horwitz MA: Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component-C3. J Immunol 144: 2771-2780, 1990.
21. Sanchez A, Espinosa P, Garcia T and Mancilla R: The 19 kDa Mycobacterium tuberculosis lipoprotein (LpqH) induces macrophage apoptosis through extrinsic and intrinsic pathways: a role for the mitochondrial apoptosis-inducing factor. Clin Dev Immunol 2012: 950503, 2012.
22. Lopez M, Sly LM, Luu Y, Young D, Cooper H and Reiner NE: The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through toll-like receptor-2. J Immunol 170: 2409-2416, 2003.
23. Thangapazham RL, Sharma A and Maheshwari RK: Multiple molecular targets in cancer chemoprevention by curcumin. AAPS J 8: E443-E449, 2006.
24. Singh RP and Agarwal R: Mechanisms of action of novel agents for prostate cancer chemoprevention. Endocr Relat Cancer 13: 751-778, 2006.
25. Salehi P, Makhoul G, Roy R, Malhotra M, Mood ZA and Daniel SJ: Curcumin loaded NIPAAM/VP/PEG-A nanoparticles: physicochemical and chemopreventive properties. J Biomater Sci Polym Ed 24: 574-588, 2013.
26. Lopez-Lazaro M: Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent. Mol Nutr Food Res 52 (Suppl 1): S103-S127, 2008.
27. Campbell FC and Collett GP: Chemopreventive properties of curcumin. Future Oncol 1: 405-414, 2005.
28. Ammon HP and Wahl MA: Pharmacology of Curcuma longa. Planta Med 57: 1-7, 1991.
29. Jee SH, Shen SC, Tseng CR, Chiu HC and Kuo ML: Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells. J Invest Dermatol 111: 656-661, 1998.
30. Uddin S, Hussain AR, Manogaran PS, et al: Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma. Oncogene 24: 7022-7030, 2005.
31. Sen S, Sharma H and Singh N: Curcumin enhances Vinorelbine mediated apoptosis in NSCLC cells by the mitochondrial pathway. Biochem Biophys Res Commun 331: 1245-1252, 2005.
32. Singh S and Aggarwal BB: Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 270: 24995-25000, 1995.
33. Bush JA, Cheung KJ Jr and Li G: Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53. Exp Cell Res 271: 305-314, 2001.
34. Watanabe I, Ichiki M, Shiratsuchi A and Nakanishi Y: TLR2-mediated survival of Staphylococcus aureus in macrophages: a novel bacterial strategy against host innate immunity. J Immunol 178: 4917-4925, 2007.