Localization of dendritic cells in the gut epithelium requires MAdCAM-1

Clinical Immunology

Volumn 156, Issue 1, 2015, Pages 74-84

  Clahsen, Thomas ^a   Pabst, Oliver ^a,b   Tenbrock, Klaus ^a   Schippers, Angela ^a   Wagner, Norbert ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Dendritic cells; ; MAdCAM 1; ; Migration; ; 7 integrin

Indexed keywords

BETA7 INTEGRIN; BROXURIDINE; CD103 ANTIGEN; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN A; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; CELL ADHESION MOLECULE; MADCAM1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CELL SUSPENSION; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; DENDRITIC CELL; FLOW CYTOMETRY; HOMEOSTASIS; IMMUNE RESPONSE; INTESTINE EPITHELIUM; MELANOMA B16; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; T LYMPHOCYTE; ANIMAL; CELL MOTION; CYTOLOGY; GENETICS; INTESTINE MUCOSA; METABOLISM;

ANIMALS; CELL ADHESION MOLECULES; CELL MOVEMENT; DENDRITIC CELLS; FLOW CYTOMETRY; INTESTINAL MUCOSA; MICE;

EID: 84914145168     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2014.11.005     Document Type: Article

References (41)

1. Steinman R.M., Banchereau J. Taking dendritic cells into medicine. Nature 2007, 449:419-426.
2. Iwasaki A. Mucosal dendritic cells. Annu. Rev. Immunol. 2007, 25:381-418.
3. Rescigno M., Di Sabatino A. Dendritic cells in intestinal homeostasis and disease. J. Clin. Invest. 2009, 119:2441-2450.
4. + dendritic cells in the regulation of tissue-selective T cell homing. J. Exp. Med. 2005, 202:1063-1073.
5. Bogunovic M., Ginhoux F., Helft J., Shang L., Hashimoto D., Greter M., Liu K., Jakubzick C., Ingersoll M.A., Leboeuf M., Stanley E.R., Nussenzweig M., Lira S.A., Randolph G.J., Merad M. Origin of the lamina propria dendritic cell network. Immunity 2009, 31:513-525.
6. Annacker O., Coombes J.L., Malmstrom V., Uhlig H.H., Bourne T., Johansson-Lindbom B., Agace W.W., Parker C.M., Powrie F. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J. Exp. Med. 2005, 202:1051-1061.
7. + regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med. 2007, 204:1757-1764.
8. +, antigen sampling cells migrate in lymph and serve classical dendritic cell functions. J. Exp. Med. 2009, 206:3101-3114.
9. Jung S., Aliberti J., Graemmel P., Sunshine M.J., Kreutzberg G.W., Sher A., Littman D.R. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell. Biol. 2000, 20:4106-4114.
10. Niess J.H., Brand S., Gu X., Landsman L., Jung S., McCormick B.A., Vyas J.M., Boes M., Ploegh H.L., Fox J.G., Littman D.R., Reinecker H.C. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 2005, 307:254-258.
11. Rescigno M., Urbano M., Valzasina B., Francolini M., Rotta G., Bonasio R., Granucci F., Kraehenbuhl J.P., Ricciardi-Castagnoli P. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol. 2001, 2:361-367.
12. Bain C.C., Mowat A.M. Macrophages in intestinal homeostasis and inflammation. Immunol. Rev. 2014, 260:102-117.
13. Contractor N., Louten J., Kim L., Biron C.A., Kelsall B.L. Cutting edge: Peyer's patch plasmacytoid dendritic cells (pDCs) produce low levels of type I interferons: possible role for IL-10, TGFbeta, and prostaglandin E2 in conditioning a unique mucosal pDC phenotype. J. Immunol. 2007, 179:2690-2694.
14. Wendland M., Czeloth N., Mach N., Malissen B., Kremmer E., Pabst O., Forster R. CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:6347-6352.
15. Swiecki M., Colonna M. Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance. Immunol. Rev. 2010, 234:142-162.
16. Goubier A., Dubois B., Gheit H., Joubert G., Villard-Truc F., Asselin-Paturel C., Trinchieri G., Kaiserlian D. Plasmacytoid dendritic cells mediate oral tolerance. Immunity 2008, 29:464-475.
17. Viney J.L., Jones S., Chiu H.H., Lagrimas B., Renz M.E., Presta L.G., Jackson D., Hillan K.J., Lew S., Fong S. Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif. J. Immunol. 1996, 157:2488-2497.
18. Butcher E.C., Williams M., Youngman K., Rott L., Briskin M. Lymphocyte trafficking and regional immunity. Adv. Immunol. 1999, 72:209-253.
19. Berg E.L., McEvoy L.M., Berlin C., Bargatze R.F., Butcher E.C. L-selectin-mediated lymphocyte rolling on MAdCAM-1. Nature 1993, 366:695-698.
20. Erle D.J., Briskin M.J., Butcher E.C., Garcia-Pardo A., Lazarovits A.I., Tidswell M. Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes. J. Immunol. 1994, 153:517-528.
21. + memory T cells with Hallmarks of gut-trophism. J. Immunol. 1993, 151:717-729.
22. Brandt E.B., Zimmermann N., Muntel E.E., Yamada Y., Pope S.M., Mishra A., Hogan S.P., Rothenberg M.E. The alpha4beta7-integrin is dynamically expressed on murine eosinophils and involved in eosinophil trafficking to the intestine. Clin. Exp. Allergy 2006, 36:543-553.
23. Gorfu G., Rivera-Nieves J., Ley K. Role of beta7 integrins in intestinal lymphocyte homing and retention. Curr. Mol. Med. 2009, 9:836-850.
24. Cepek K.L., Parker C.M., Madara J.L., Brenner M.B. Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J. Immunol. 1993, 150:3459-3470.
25. Wagner N., Lohler J., Kunkel E.J., Ley K., Leung E., Krissansen G., Rajewsky K., Muller W. Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature 1996, 382:366-370.
26. Schon M.P., Arya A., Murphy E.A., Adams C.M., Strauch U.G., Agace W.W., Marsal J., Donohue J.P., Her H., Beier D.R., Olson S., Lefrancois L., Brenner M.B., Grusby M.J., Parker C.M. Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice. J. Immunol. 1999, 162:6641-6649.
27. Villablanca E.J., De Calisto J., Torregrosa Paredes P., Cassani B., Nguyen D.D., Gabrielsson S., Mora J.R. Beta7 integrins are required to give rise to intestinal mononuclear phagocytes with tolerogenic potential. Gut 2014, 63:1431-1440.
28. Zeng R., Oderup C., Yuan R., Lee M., Habtezion A., Hadeiba H., Butcher E.C. Retinoic acid regulates the development of a gut-homing precursor for intestinal dendritic cells. Mucosal Immunol. 2013, 6:847-856.
29. Mach N., Gillessen S., Wilson S.B., Sheehan C., Mihm M., Dranoff G. Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand. Cancer Res. 2000, 60:3239-3246.
30. + dendritic cells into the intestinal epithelium to sample bacterial antigens for presentation. Immunity 2013, 38:581-595.
31. Kuklin N.A., Rott L., Darling J., Campbell J.J., Franco M., Feng N., Muller W., Wagner N., Altman J., Butcher E.C., Greenberg H.B. Alpha(4)beta(7) independent pathway for CD8(+) T cell-mediated intestinal immunity to rotavirus. J. Clin. Invest. 2000, 106:1541-1552.
32. Liu K., Victora G.D., Schwickert T.A., Guermonprez P., Meredith M.M., Yao K., Chu F.F., Randolph G.J., Rudensky A.Y., Nussenzweig M. In vivo analysis of dendritic cell development and homeostasis. Science 2009, 324:392-397.
33. + dendritic cells display unique functional properties that are conserved between mice and humans. J. Exp. Med. 2008, 205:2139-2149.
34. Liu K., Waskow C., Liu X., Yao K., Hoh J., Nussenzweig M. Origin of dendritic cells in peripheral lymphoid organs of mice. Nat. Immunol. 2007, 8:578-583.
35. Varol C., Vallon-Eberhard A., Elinav E., Aychek T., Shapira Y., Luche H., Fehling H.J., Hardt W.D., Shakhar G., Jung S. Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity 2009, 31:502-512.
36. Yrlid U., Cerovic V., Milling S., Jenkins C.D., Klavinskis L.S., MacPherson G.G. A distinct subset of intestinal dendritic cells responds selectively to oral TLR7/8 stimulation. Eur. J. Immunol. 2006, 36:2639-2648.
37. Mullaly S.C., Burrows K., Antignano F., Zaph C. Assessing the role of CD103 in immunity to an intestinal helminth parasite. PLoS One 2011, 6:e19580.
38. Shortman K., Sathe P., Vremec D., Naik S., O'Keeffe M. Plasmacytoid dendritic cell development. Adv. Immunol. 2013, 120:105-126.
39. Geissmann F., Manz M.G., Jung S., Sieweke M.H., Merad M., Ley K. Development of monocytes, macrophages, and dendritic cells. Science 2010, 327:656-661.
40. Cassani B., Villablanca E.J., Quintana F.J., Love P.E., Lacy-Hulbert A., Blaner W.S., Sparwasser T., Snapper S.B., Weiner H.L., Mora J.R. Gut-tropic T cells that express integrin alpha4beta7 and CCR9 are required for induction of oral immune tolerance in mice. Gastroenterology 2011, 141:2109-2118.
41. Schippers A., Kochut A., Pabst O., Frischmann U., Clahsen T., Tenbrock K., Muller W., Wagner N. Beta7 integrin controls immunogenic and tolerogenic mucosal B cell responses. Clin. Immunol. 2012, 144:87-97.