메뉴 건너뛰기




Volumn 135, Issue 2, 2014, Pages 349-358

The search for biomarkers to direct antiangiogenic treatment in epithelial ovarian cancer

Author keywords

Antiangiogenic agents; Biomarkers; Epithelial ovarian cancer

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOPOIETIN 1; ANGIOPOIETIN 2; BEVACIZUMAB; BIOLOGICAL MARKER; CD31 ANTIGEN; CISPLATIN; DOCETAXEL; FIBROBLAST GROWTH FACTOR; FLUOROURACIL; GEMCITABINE; INTERLEUKIN 6; MESOTHELIN; MOTESANIB; OCTREOTIDE; OROSOMUCOID; OSTEOPONTIN; PAZOPANIB; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE KINASE INHIBITOR; SORAFENIB; STROMAL CELL DERIVED FACTOR 1; TEMSIROLIMUS; UNINDEXED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN D; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3; TUMOR MARKER;

EID: 84913610076     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2014.08.033     Document Type: Review
Times cited : (25)

References (93)
  • 1
    • 79952818552 scopus 로고    scopus 로고
    • Overview of anti-angiogenic agents in development for ovarian cancer
    • R.A. Burger Overview of anti-angiogenic agents in development for ovarian cancer Gynecol Oncol 121 2011 230 238
    • (2011) Gynecol Oncol , vol.121 , pp. 230-238
    • Burger, R.A.1
  • 2
    • 41849092178 scopus 로고    scopus 로고
    • Angiogenesis as a strategic target for ovarian cancer therapy
    • W.A. Spannuth, A.K. Sood, and R.L. Coleman Angiogenesis as a strategic target for ovarian cancer therapy Nat Clin Pract Oncol 5 2008 194 204
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 194-204
    • Spannuth, W.A.1    Sood, A.K.2    Coleman, R.L.3
  • 3
    • 77954722597 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptors VEGFR-2 and VEGFR-3 are localized primarily to the vasculature in human primary solid cancers
    • N.R. Smith, D. Baker, and N.H. James Vascular endothelial growth factor receptors VEGFR-2 and VEGFR-3 are localized primarily to the vasculature in human primary solid cancers Clin Cancer Res 16 2010 3548 3561
    • (2010) Clin Cancer Res , vol.16 , pp. 3548-3561
    • Smith, N.R.1    Baker, D.2    James, N.H.3
  • 4
    • 84855425106 scopus 로고    scopus 로고
    • Incorporation of bevacizumab in the primary treatment of ovarian cancer
    • R.A. Burger, M.F. Brady, and M.A. Bookman Incorporation of bevacizumab in the primary treatment of ovarian cancer N Engl J Med 365 2011 2473 2483
    • (2011) N Engl J Med , vol.365 , pp. 2473-2483
    • Burger, R.A.1    Brady, M.F.2    Bookman, M.A.3
  • 5
    • 84855466019 scopus 로고    scopus 로고
    • A phase 3 trial of bevacizumab in ovarian cancer
    • T.J. Perren, A.M. Swart, and J. Pfisterer A phase 3 trial of bevacizumab in ovarian cancer N Engl J Med 365 2011 2484 2496
    • (2011) N Engl J Med , vol.365 , pp. 2484-2496
    • Perren, T.J.1    Swart, A.M.2    Pfisterer, J.3
  • 6
    • 84861736119 scopus 로고    scopus 로고
    • OCEANS: A randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer
    • C. Aghajanian, S.V. Blank, and B.A. Goff OCEANS: a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer J Clin Oncol 30 2012 2039 2045
    • (2012) J Clin Oncol , vol.30 , pp. 2039-2045
    • Aghajanian, C.1    Blank, S.V.2    Goff, B.A.3
  • 7
    • 84866493383 scopus 로고    scopus 로고
    • AURELIA: A randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC)
    • [Abstract LBA5002]
    • E. Pujade-Lauraine, F. Hilpert, and B. Weber AURELIA: a randomized phase III trial evaluating bevacizumab (BEV) plus chemotherapy (CT) for platinum (PT)-resistant recurrent ovarian cancer (OC) J Clin Oncol 30 2012 [Abstract LBA5002]
    • (2012) J Clin Oncol , vol.30
    • Pujade-Lauraine, E.1    Hilpert, F.2    Weber, B.3
  • 8
    • 84873054760 scopus 로고    scopus 로고
    • Advanced ovarian cancer: What should be the standard of care?
    • B.A. Goff Advanced ovarian cancer: what should be the standard of care? J Gynecol Oncol 24 2013 83 91
    • (2013) J Gynecol Oncol , vol.24 , pp. 83-91
    • Goff, B.A.1
  • 9
    • 84894046261 scopus 로고    scopus 로고
    • AGO-OVAR 12: A randomized placebo-controlled GCIG/ENGOT-intergroup phase III trial of standard frontline chemotherapy +/- nintedanib for advanced ovarian cancer
    • A. du Bois, G. Kristensen, and I. Ray-Coquard AGO-OVAR 12: a randomized placebo-controlled GCIG/ENGOT-intergroup phase III trial of standard frontline chemotherapy +/- nintedanib for advanced ovarian cancer Int J Gynecol Cancer 23 2013 LBA 1
    • (2013) Int J Gynecol Cancer , vol.23 , pp. 1
    • Du Bois, A.1    Kristensen, G.2    Ray-Coquard, I.3
  • 11
    • 84975065203 scopus 로고    scopus 로고
    • A phase III, randomized, double-blind trial of weekly paclitaxel plus the angiopoietin 1 and 2 inhibitor, trebananib, or placebo in women with recurrent ovarian cancer: TRINOVA-1
    • [Abstract 41]
    • B.J. Monk, A. Poveda, and I. Vergote A phase III, randomized, double-blind trial of weekly paclitaxel plus the angiopoietin 1 and 2 inhibitor, trebananib, or placebo in women with recurrent ovarian cancer: TRINOVA-1 Presented at: the European Cancer Congress; September 27-October 1, 2013; Amsterdam, Netherlands 2013 [Abstract 41]
    • (2013) Presented At: The European Cancer Congress; September 27-October 1, 2013; Amsterdam, Netherlands
    • Monk, B.J.1    Poveda, A.2    Vergote, I.3
  • 12
    • 0035187771 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Its prognostic, predictive, and therapeutic implications
    • M. Toi, T. Matsumoto, and H. Bando Vascular endothelial growth factor: its prognostic, predictive, and therapeutic implications Lancet Oncol 2 2001 667 673
    • (2001) Lancet Oncol , vol.2 , pp. 667-673
    • Toi, M.1    Matsumoto, T.2    Bando, H.3
  • 13
    • 0036793818 scopus 로고    scopus 로고
    • Preoperative serum vascular endothelial growth factor levels: Significance in ovarian cancer
    • B.C. Cooper, J.M. Ritchie, and C.L. Broghammer Preoperative serum vascular endothelial growth factor levels: significance in ovarian cancer Clin Cancer Res 8 2002 3193 3197
    • (2002) Clin Cancer Res , vol.8 , pp. 3193-3197
    • Cooper, B.C.1    Ritchie, J.M.2    Broghammer, C.L.3
  • 14
    • 1842850792 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and interleukin-8 are associated with poor prognosis in epithelial ovarian cancer patients
    • S.K. Kassim, E.M. El-Salahy, and S.T. Fayed Vascular endothelial growth factor and interleukin-8 are associated with poor prognosis in epithelial ovarian cancer patients Clin Biochem 37 2004 363 369
    • (2004) Clin Biochem , vol.37 , pp. 363-369
    • Kassim, S.K.1    El-Salahy, E.M.2    Fayed, S.T.3
  • 15
    • 3242658330 scopus 로고    scopus 로고
    • Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer
    • L. Li, L. Wang, and W. Zhang Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer Anticancer Res 24 2004 1973 1979
    • (2004) Anticancer Res , vol.24 , pp. 1973-1979
    • Li, L.1    Wang, L.2    Zhang, W.3
  • 16
    • 33751006991 scopus 로고    scopus 로고
    • Preoperative serum vascular endothelial growth factor as a prognostic parameter in ovarian cancer
    • L.A. Hefler, R. Zeillinger, and C. Grimm Preoperative serum vascular endothelial growth factor as a prognostic parameter in ovarian cancer Gynecol Oncol 103 2006 512 517
    • (2006) Gynecol Oncol , vol.103 , pp. 512-517
    • Hefler, L.A.1    Zeillinger, R.2    Grimm, C.3
  • 17
    • 49649107704 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in ovarian cancer: A model for targeted use of novel therapies?
    • T.J. Duncan, A. Al-Attar, and P. Rolland Vascular endothelial growth factor expression in ovarian cancer: a model for targeted use of novel therapies? Clin Cancer Res 14 2008 3030 3035
    • (2008) Clin Cancer Res , vol.14 , pp. 3030-3035
    • Duncan, T.J.1    Al-Attar, A.2    Rolland, P.3
  • 18
    • 78149359739 scopus 로고    scopus 로고
    • Predictive and prognostic angiogenic markers in a gynecologic oncology group phase II trial of bevacizumab in recurrent and persistent ovarian or peritoneal cancer
    • E.S. Han, R.A. Burger, and K.M. Darcy Predictive and prognostic angiogenic markers in a gynecologic oncology group phase II trial of bevacizumab in recurrent and persistent ovarian or peritoneal cancer Gynecol Oncol 119 2010 484 490
    • (2010) Gynecol Oncol , vol.119 , pp. 484-490
    • Han, E.S.1    Burger, R.A.2    Darcy, K.M.3
  • 19
    • 84874095390 scopus 로고    scopus 로고
    • Predictive impact of circulating vascular endothelial growth factor in four phase III trials evaluating bevacizumab
    • P.S. Hegde, A.M. Jubb, and D. Chen Predictive impact of circulating vascular endothelial growth factor in four phase III trials evaluating bevacizumab Clin Cancer Res 19 2013 929 937
    • (2013) Clin Cancer Res , vol.19 , pp. 929-937
    • Hegde, P.S.1    Jubb, A.M.2    Chen, D.3
  • 21
    • 84859156536 scopus 로고    scopus 로고
    • Targeting angiogenesis in ovarian cancer
    • J. Schmitt, and D. Matei Targeting angiogenesis in ovarian cancer Cancer Treat Rev 38 2012 272 283
    • (2012) Cancer Treat Rev , vol.38 , pp. 272-283
    • Schmitt, J.1    Matei, D.2
  • 22
    • 77954169274 scopus 로고    scopus 로고
    • Significance of phospho-vascular endothelial growth factor receptor-2 expression in pancreatic cancer
    • Y. Doi, M. Yashiro, and N. Yamada Significance of phospho-vascular endothelial growth factor receptor-2 expression in pancreatic cancer Cancer Sci 101 2010 1529 1535
    • (2010) Cancer Sci , vol.101 , pp. 1529-1535
    • Doi, Y.1    Yashiro, M.2    Yamada, N.3
  • 23
    • 84856801993 scopus 로고    scopus 로고
    • Increased gene copy number of KIT and VEGFR2 at 4q12 in primary breast cancer is related to an aggressive phenotype and impaired prognosis
    • I. Johansson, K.E. Aaltonen, and A. Ebbesson Increased gene copy number of KIT and VEGFR2 at 4q12 in primary breast cancer is related to an aggressive phenotype and impaired prognosis Genes Chromosomes Cancer 51 2012 375 383
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 375-383
    • Johansson, I.1    Aaltonen, K.E.2    Ebbesson, A.3
  • 24
    • 84872194939 scopus 로고    scopus 로고
    • Biomarker (BM) results from GOG-0218, a phase 3 trial of front-line bevacizumab (BV) + chemotherapy (CT) for ovarian cancer (OC)
    • [Abstract 198P]
    • M.J. Birrer, H. Lankes, and R.A. Burger Biomarker (BM) results from GOG-0218, a phase 3 trial of front-line bevacizumab (BV) + chemotherapy (CT) for ovarian cancer (OC) Ann Oncol 23 ix81 2012 [Abstract 198P]
    • (2012) Ann Oncol , vol.23 , Issue.IX81
    • Birrer, M.J.1    Lankes, H.2    Burger, R.A.3
  • 26
    • 0031213636 scopus 로고    scopus 로고
    • VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
    • S.J. Oh, M.M. Jeltsch, and R. Birkenhager VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane Dev Biol 188 1997 96 109
    • (1997) Dev Biol , vol.188 , pp. 96-109
    • Oh, S.J.1    Jeltsch, M.M.2    Birkenhager, R.3
  • 27
    • 39449096958 scopus 로고    scopus 로고
    • Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b + macrophages in advanced ovarian cancer
    • B.H. Jeon, C. Jang, and J. Han Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b + macrophages in advanced ovarian cancer Cancer Res 68 2008 1100 1109
    • (2008) Cancer Res , vol.68 , pp. 1100-1109
    • Jeon, B.H.1    Jang, C.2    Han, J.3
  • 29
    • 79251473728 scopus 로고    scopus 로고
    • Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer
    • A.M. Jubb, K.D. Miller, and H.S. Rugo Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer Clin Cancer Res 17 2011 372 381
    • (2011) Clin Cancer Res , vol.17 , pp. 372-381
    • Jubb, A.M.1    Miller, K.D.2    Rugo, H.S.3
  • 30
    • 0037468102 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma
    • Y. Yokoyama, D.S. Charnock-Jones, and D. Licence Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma Br J Cancer 88 2003 237 244
    • (2003) Br J Cancer , vol.88 , pp. 237-244
    • Yokoyama, Y.1    Charnock-Jones, D.S.2    Licence, D.3
  • 31
    • 84890774281 scopus 로고    scopus 로고
    • Prognostic and predictive blood-based biomarkers in patients with advanced pancreatic cancer: Results from CALGB80303 (Alliance)
    • A.B. Nixon, H. Pang, and M.D. Starr Prognostic and predictive blood-based biomarkers in patients with advanced pancreatic cancer: results from CALGB80303 (Alliance) Clin Cancer Res 19 2013 6957-6966
    • (2013) Clin Cancer Res , vol.19 , pp. 6957-6966
    • Nixon, A.B.1    Pang, H.2    Starr, M.D.3
  • 32
    • 84884562902 scopus 로고    scopus 로고
    • Predicting response to bevacizumab in ovarian cancer: A panel of potential biomarkers informing treatment selection
    • F. Collinson, M. Hutchinson, and R.A. Craven Predicting response to bevacizumab in ovarian cancer: a panel of potential biomarkers informing treatment selection Clin Cancer Res 19 2013 5227 5239
    • (2013) Clin Cancer Res , vol.19 , pp. 5227-5239
    • Collinson, F.1    Hutchinson, M.2    Craven, R.A.3
  • 33
    • 58749097443 scopus 로고    scopus 로고
    • Functional significance of VEGFR-2 on ovarian cancer cells
    • W.A. Spannuth, A.M. Nick, and N.B. Jennings Functional significance of VEGFR-2 on ovarian cancer cells Int J Cancer 124 2009 1045 1053
    • (2009) Int J Cancer , vol.124 , pp. 1045-1053
    • Spannuth, W.A.1    Nick, A.M.2    Jennings, N.B.3
  • 34
    • 70350571185 scopus 로고    scopus 로고
    • VEGFR-2 silencing by small interference RNA (siRNA) suppresses LPA-induced epithelial ovarian cancer (EOC) invasion
    • F.Q. Wang, E. Barfield, S. Dutta, T. Pua, and D.A. Fishman VEGFR-2 silencing by small interference RNA (siRNA) suppresses LPA-induced epithelial ovarian cancer (EOC) invasion Gynecol Oncol 115 2009 414 423
    • (2009) Gynecol Oncol , vol.115 , pp. 414-423
    • Wang, F.Q.1    Barfield, E.2    Dutta, S.3    Pua, T.4    Fishman, D.A.5
  • 35
    • 57849106330 scopus 로고    scopus 로고
    • PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment
    • Y. Crawford, I. Kasman, and L. Yu PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment Cancer Cell 15 2009 21 34
    • (2009) Cancer Cell , vol.15 , pp. 21-34
    • Crawford, Y.1    Kasman, I.2    Yu, L.3
  • 36
    • 34547100525 scopus 로고    scopus 로고
    • Dual targeting of endothelial cells and pericytes in antivascular therapy for ovarian carcinoma
    • C. Lu, A.A. Kamat, and Y.G. Lin Dual targeting of endothelial cells and pericytes in antivascular therapy for ovarian carcinoma Clin Cancer Res 13 2007 4209 4217
    • (2007) Clin Cancer Res , vol.13 , pp. 4209-4217
    • Lu, C.1    Kamat, A.A.2    Lin, Y.G.3
  • 37
    • 41349089301 scopus 로고    scopus 로고
    • Impact of vessel maturation on antiangiogenic therapy in ovarian cancer
    • C. Lu, P.H. Thaker, and Y.G. Lin Impact of vessel maturation on antiangiogenic therapy in ovarian cancer Am J Obstet Gynecol 198 2008 477 479
    • (2008) Am J Obstet Gynecol , vol.198 , pp. 477-479
    • Lu, C.1    Thaker, P.H.2    Lin, Y.G.3
  • 38
    • 20044396551 scopus 로고    scopus 로고
    • Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab′, leads to fluid accumulation and is associated with increased tumor vascularized volume
    • G.C. Jayson, G.J. Parker, and S. Mullamitha Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab′, leads to fluid accumulation and is associated with increased tumor vascularized volume J Clin Oncol 23 2005 973 981
    • (2005) J Clin Oncol , vol.23 , pp. 973-981
    • Jayson, G.C.1    Parker, G.J.2    Mullamitha, S.3
  • 39
    • 34250200790 scopus 로고    scopus 로고
    • Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas
    • M.J. Birrer, M.E. Johnson, and K. Hao Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas J Clin Oncol 25 2007 2281 2287
    • (2007) J Clin Oncol , vol.25 , pp. 2281-2287
    • Birrer, M.J.1    Johnson, M.E.2    Hao, K.3
  • 40
    • 0035855624 scopus 로고    scopus 로고
    • Induction of FGF receptor 2-IIIb expression and response to its ligands in epithelial ovarian cancer
    • I.A. Steele, R.J. Edmondson, J.N. Bulmer, B.S. Bolger, H.Y. Leung, and B.R. Davies Induction of FGF receptor 2-IIIb expression and response to its ligands in epithelial ovarian cancer Oncogene 20 2001 5878 5887
    • (2001) Oncogene , vol.20 , pp. 5878-5887
    • Steele, I.A.1    Edmondson, R.J.2    Bulmer, J.N.3    Bolger, B.S.4    Leung, H.Y.5    Davies, B.R.6
  • 41
    • 0032542703 scopus 로고    scopus 로고
    • Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice
    • J. Yoneda, H. Kuniyasu, M.A. Crispens, J.E. Price, C.D. Bucana, and I.J. Fidler Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice J Natl Cancer Inst 90 1998 447 454
    • (1998) J Natl Cancer Inst , vol.90 , pp. 447-454
    • Yoneda, J.1    Kuniyasu, H.2    Crispens, M.A.3    Price, J.E.4    Bucana, C.D.5    Fidler, I.J.6
  • 42
    • 0142248954 scopus 로고    scopus 로고
    • Vascular endothelial growth factor synthesis by human omental mesothelial cells is augmented by fibroblast growth factor-2: Possible role of mesothelial cell on the development of peritoneal metastasis
    • A. Sako, J. Kitayama, and H. Yamaguchi Vascular endothelial growth factor synthesis by human omental mesothelial cells is augmented by fibroblast growth factor-2: possible role of mesothelial cell on the development of peritoneal metastasis J Surg Res 115 2003 113 120
    • (2003) J Surg Res , vol.115 , pp. 113-120
    • Sako, A.1    Kitayama, J.2    Yamaguchi, H.3
  • 44
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • O. Casanovas, D.J. Hicklin, G. Bergers, and D. Hanahan Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors Cancer Cell 8 2005 299 309
    • (2005) Cancer Cell , vol.8 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 45
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • T.T. Batchelor, A.G. Sorensen, and E. di Tomaso AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients Cancer Cell 11 2007 83 95
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    Di Tomaso, E.3
  • 47
    • 34547401519 scopus 로고    scopus 로고
    • Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2
    • S.F. Winter, V.D. Acevedo, R.D. Gangula, K.W. Freeman, D.M. Spencer, and N.M. Greenberg Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2 Oncogene 26 2007 4897 4907
    • (2007) Oncogene , vol.26 , pp. 4897-4907
    • Winter, S.F.1    Acevedo, V.D.2    Gangula, R.D.3    Freeman, K.W.4    Spencer, D.M.5    Greenberg, N.M.6
  • 48
  • 50
    • 85067715541 scopus 로고    scopus 로고
    • Measurement of baseline serum SDF-1 levels as a predictive biomarker for outcomes in the NCIC CTG MA. 14 trial of octreotide, a somatostatin analogue in postmenopausal breast cancer
    • [Abstract 577]
    • A. Aguilar-Mahecha, M. Basik, and J.W. Chapman Measurement of baseline serum SDF-1 levels as a predictive biomarker for outcomes in the NCIC CTG MA. 14 trial of octreotide, a somatostatin analogue in postmenopausal breast cancer J Clin Oncol 29 2011 [Abstract 577]
    • (2011) J Clin Oncol , vol.29
    • Aguilar-Mahecha, A.1    Basik, M.2    Chapman, J.W.3
  • 51
    • 85067721248 scopus 로고    scopus 로고
    • Angiogenic marker associated with resistance to neoadjuvant chemoradiotherapy in rectal cancer
    • [Abstract 11030]
    • H. Kim, M.Y. Lee, and T.S. Ahn Angiogenic marker associated with resistance to neoadjuvant chemoradiotherapy in rectal cancer J Clin Oncol 31 2013 [Abstract 11030]
    • (2013) J Clin Oncol , vol.31
    • Kim, H.1    Lee, M.Y.2    Ahn, T.S.3
  • 53
    • 33744460515 scopus 로고    scopus 로고
    • Preoperative plasma osteopontin level as a biomarker complementary to carbohydrate antigen 125 in predicting ovarian cancer
    • M. Nakae, I. Iwamoto, and T. Fujino Preoperative plasma osteopontin level as a biomarker complementary to carbohydrate antigen 125 in predicting ovarian cancer J Obstet Gynaecol Res 32 2006 309 314
    • (2006) J Obstet Gynaecol Res , vol.32 , pp. 309-314
    • Nakae, M.1    Iwamoto, I.2    Fujino, T.3
  • 54
    • 84913609540 scopus 로고    scopus 로고
    • The role of serum osteopontin (OPN) as a prognostic and predictive marker in patients with advanced gastric cancer
    • [Abstract e14627]
    • O. Yazici, H. Akbulut, N. Akgun, G. Utkan, B. Yalcin, and F. Idi The role of serum osteopontin (OPN) as a prognostic and predictive marker in patients with advanced gastric cancer J Clin Oncol 29 2011 [Abstract e14627]
    • (2011) J Clin Oncol , vol.29
    • Yazici, O.1    Akbulut, H.2    Akgun, N.3    Utkan, G.4    Yalcin, B.5    Idi, F.6
  • 55
    • 84867499521 scopus 로고    scopus 로고
    • Interleukin-6/interleukin-6 receptor pathway as a new therapy target in epithelial ovarian cancer
    • E.M. Dijkgraaf, M.J. Welters, J.W. Nortier, S.H. van der Burg, and J.R. Kroep Interleukin-6/interleukin-6 receptor pathway as a new therapy target in epithelial ovarian cancer Curr Pharm Des 18 2012 3816 3827
    • (2012) Curr Pharm des , vol.18 , pp. 3816-3827
    • Dijkgraaf, E.M.1    Welters, M.J.2    Nortier, J.W.3    Van Der Burg, S.H.4    Kroep, J.R.5
  • 56
    • 84864333467 scopus 로고    scopus 로고
    • Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: A retrospective analysis of phase 2 and phase 3 trials
    • H.T. Tran, Y. Liu, and A.J. Zurita Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials Lancet Oncol 13 2012 827 837
    • (2012) Lancet Oncol , vol.13 , pp. 827-837
    • Tran, H.T.1    Liu, Y.2    Zurita, A.J.3
  • 57
    • 84885650535 scopus 로고    scopus 로고
    • Identification of predictive biomarkers of overall survival (OS) in patients (pts) with advanced renal cell carcinoma (RCC) treated with interferon alpha (I) with or without bevacizumab (B): Results from CALGB 90206 (Alliance)
    • [Abstract 4520]
    • A.B. Nixon, S. Halabi, and I. Shterev Identification of predictive biomarkers of overall survival (OS) in patients (pts) with advanced renal cell carcinoma (RCC) treated with interferon alpha (I) with or without bevacizumab (B): results from CALGB 90206 (Alliance) J Clin Oncol 31 2013 [Abstract 4520]
    • (2013) J Clin Oncol , vol.31
    • Nixon, A.B.1    Halabi, S.2    Shterev, I.3
  • 58
    • 84913618495 scopus 로고    scopus 로고
    • Circulating cytokines and angiogenic factors (CAF) as markers of clinical response in the study of trametinib (T) plus gemcitabine (G) versus placebo (P) plus gemcitabine for patients (pts) with untreated metastatic adenocarcinoma of the pancreas (MEK113487)
    • [Abstract 4042]
    • J. Heymach, H.T. Tran, and A.B. Nixon Circulating cytokines and angiogenic factors (CAF) as markers of clinical response in the study of trametinib (T) plus gemcitabine (G) versus placebo (P) plus gemcitabine for patients (pts) with untreated metastatic adenocarcinoma of the pancreas (MEK113487) J Clin Oncol 31 2013 [Abstract 4042]
    • (2013) J Clin Oncol , vol.31
    • Heymach, J.1    Tran, H.T.2    Nixon, A.B.3
  • 59
    • 58149165081 scopus 로고    scopus 로고
    • Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer
    • J.S. de Bono, H.I. Scher, and R.B. Montgomery Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer Clin Cancer Res 14 2008 6302 6309
    • (2008) Clin Cancer Res , vol.14 , pp. 6302-6309
    • De Bono, J.S.1    Scher, H.I.2    Montgomery, R.B.3
  • 60
    • 79952764349 scopus 로고    scopus 로고
    • Phase I/II study of pemetrexed with or without ABT-751 in advanced or metastatic non-small-cell lung cancer
    • C.M. Rudin, A. Mauer, and M. Smakal Phase I/II study of pemetrexed with or without ABT-751 in advanced or metastatic non-small-cell lung cancer J Clin Oncol 29 2011 1075 1082
    • (2011) J Clin Oncol , vol.29 , pp. 1075-1082
    • Rudin, C.M.1    Mauer, A.2    Smakal, M.3
  • 61
    • 4143094988 scopus 로고    scopus 로고
    • Circulating tumor cells, disease progression, and survival in metastatic breast cancer
    • M. Cristofanilli, G.T. Budd, and M.J. Ellis Circulating tumor cells, disease progression, and survival in metastatic breast cancer N Engl J Med 351 2004 781 791
    • (2004) N Engl J Med , vol.351 , pp. 781-791
    • Cristofanilli, M.1    Budd, G.T.2    Ellis, M.J.3
  • 62
    • 80052588957 scopus 로고    scopus 로고
    • Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: A Gynecologic Oncology Group study
    • K. Behbakht, M.W. Sill, and K.M. Darcy Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a Gynecologic Oncology Group study Gynecol Oncol 123 2011 19 26
    • (2011) Gynecol Oncol , vol.123 , pp. 19-26
    • Behbakht, K.1    Sill, M.W.2    Darcy, K.M.3
  • 63
    • 84875461329 scopus 로고    scopus 로고
    • A phase II evaluation of motesanib (AMG 706) in the treatment of persistent or recurrent ovarian, fallopian tube and primary peritoneal carcinomas: A Gynecologic Oncology Group study
    • R.J. Schilder, M.W. Sill, and H.A. Lankes A phase II evaluation of motesanib (AMG 706) in the treatment of persistent or recurrent ovarian, fallopian tube and primary peritoneal carcinomas: a Gynecologic Oncology Group study Gynecol Oncol 129 2013 86 91
    • (2013) Gynecol Oncol , vol.129 , pp. 86-91
    • Schilder, R.J.1    Sill, M.W.2    Lankes, H.A.3
  • 64
    • 54949123511 scopus 로고    scopus 로고
    • Immunohistochemistry in the evaluation of neovascularization in tumor xenografts
    • D. Wang, C.R. Stockard, and L. Harkins Immunohistochemistry in the evaluation of neovascularization in tumor xenografts Biotech Histochem 83 2008 179 189
    • (2008) Biotech Histochem , vol.83 , pp. 179-189
    • Wang, D.1    Stockard, C.R.2    Harkins, L.3
  • 65
    • 84873503854 scopus 로고    scopus 로고
    • Significance analysis of prognostic signatures
    • A.H. Beck, N.W. Knoblauch, and M.M. Hefti Significance analysis of prognostic signatures PLoS Comput Biol 9 2013 e1002875
    • (2013) PLoS Comput Biol , vol.9 , pp. 1002875
    • Beck, A.H.1    Knoblauch, N.W.2    Hefti, M.M.3
  • 66
    • 84863139258 scopus 로고    scopus 로고
    • Angiogenic mRNA and microRNA gene expression signature predicts a novel subtype of serous ovarian cancer
    • S. Bentink, B. Haibe-Kains, and T. Risch Angiogenic mRNA and microRNA gene expression signature predicts a novel subtype of serous ovarian cancer PLoS One 7 2012 e30269
    • (2012) PLoS One , vol.7 , pp. 30269
    • Bentink, S.1    Haibe-Kains, B.2    Risch, T.3
  • 67
    • 85067726993 scopus 로고    scopus 로고
    • Prognostic significance of differential expression of angiogenic genes in women with invasive high-grade serous ovarian carcinoma
    • [Abstract 5509]
    • S. Siamakpour-Reihani, K. Owzar, and C. Jiang Prognostic significance of differential expression of angiogenic genes in women with invasive high-grade serous ovarian carcinoma J Clin Oncol 31 2013 [Abstract 5509]
    • (2013) J Clin Oncol , vol.31
    • Siamakpour-Reihani, S.1    Owzar, K.2    Jiang, C.3
  • 68
    • 84913616149 scopus 로고    scopus 로고
    • Prognostic relevance of gene signatures in high-grade serous ovarian carcinoma
    • [Abstract 5510]
    • G.E. Konecny, C. Wang, and B. Winterhoff Prognostic relevance of gene signatures in high-grade serous ovarian carcinoma J Clin Oncol 31 2013 [Abstract 5510]
    • (2013) J Clin Oncol , vol.31
    • Konecny, G.E.1    Wang, C.2    Winterhoff, B.3
  • 69
    • 84855593872 scopus 로고    scopus 로고
    • Biomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies
    • R. Ben-Hamo, and S. Efroni Biomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies BMC Syst Biol 6 2012 3
    • (2012) BMC Syst Biol , vol.6 , pp. 3
    • Ben-Hamo, R.1    Efroni, S.2
  • 70
    • 84901652486 scopus 로고    scopus 로고
    • MiR-378 as a biomarker for response to anti-angiogenic treatment in ovarian cancer
    • J.K. Chan, T.K. Kiet, and K. Blansit MiR-378 as a biomarker for response to anti-angiogenic treatment in ovarian cancer Gynecol Oncol 133 2014 568 574
    • (2014) Gynecol Oncol , vol.133 , pp. 568-574
    • Chan, J.K.1    Kiet, T.K.2    Blansit, K.3
  • 71
    • 84856466661 scopus 로고    scopus 로고
    • The role of EZH2 in tumour progression
    • C.J. Chang, and M.C. Hung The role of EZH2 in tumour progression Br J Cancer 106 2012 243 247
    • (2012) Br J Cancer , vol.106 , pp. 243-247
    • Chang, C.J.1    Hung, M.C.2
  • 72
    • 77955541508 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by EZH2
    • C. Lu, H.D. Han, and L.S. Mangala Regulation of tumor angiogenesis by EZH2 Cancer Cell 18 2010 185 197
    • (2010) Cancer Cell , vol.18 , pp. 185-197
    • Lu, C.1    Han, H.D.2    Mangala, L.S.3
  • 73
    • 53749093040 scopus 로고    scopus 로고
    • Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100
    • B.P. Schneider, M. Wang, and M. Radovich Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100 J Clin Oncol 26 2008 4672 4678
    • (2008) J Clin Oncol , vol.26 , pp. 4672-4678
    • Schneider, B.P.1    Wang, M.2    Radovich, M.3
  • 74
    • 84908319663 scopus 로고    scopus 로고
    • Molecular subgroup of high-grade serous ovarian cancer (HGSOC) as a predictor of outcome following bevacizumab
    • [Abstract 5502]
    • C. Gourley, A. McCavigan, and T. Perren Molecular subgroup of high-grade serous ovarian cancer (HGSOC) as a predictor of outcome following bevacizumab J Clin Oncol 32 2014 [Abstract 5502]
    • (2014) J Clin Oncol , vol.32
    • Gourley, C.1    McCavigan, A.2    Perren, T.3
  • 77
    • 84855186144 scopus 로고    scopus 로고
    • Toxicity as a biomarker of efficacy of molecular targeted therapies: Focus on EGFR and VEGF inhibiting anticancer drugs
    • R. Dienstmann, I. Brana, J. Rodon, and J. Tabernero Toxicity as a biomarker of efficacy of molecular targeted therapies: focus on EGFR and VEGF inhibiting anticancer drugs Oncologist 16 2011 1729 1740
    • (2011) Oncologist , vol.16 , pp. 1729-1740
    • Dienstmann, R.1    Brana, I.2    Rodon, J.3    Tabernero, J.4
  • 78
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • S.M. Wilhelm, C. Carter, and L. Tang BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis Cancer Res 64 2004 7099 7109
    • (2004) Cancer Res , vol.64 , pp. 7099-7109
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3
  • 79
    • 79960096827 scopus 로고    scopus 로고
    • Normalization of the vasculature for treatment of cancer and other diseases
    • S. Goel, D.G. Duda, and L. Xu Normalization of the vasculature for treatment of cancer and other diseases Physiol Rev 91 2011 1071 1121
    • (2011) Physiol Rev , vol.91 , pp. 1071-1121
    • Goel, S.1    Duda, D.G.2    Xu, L.3
  • 80
    • 79959765946 scopus 로고    scopus 로고
    • DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6
    • J.P. O'Connor, C.J. Rose, and A. Jackson DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6 Br J Cancer 105 2011 139 145
    • (2011) Br J Cancer , vol.105 , pp. 139-145
    • O'Connor, J.P.1    Rose, C.J.2    Jackson, A.3
  • 81
    • 34547121206 scopus 로고    scopus 로고
    • Hypoxia in cancer: Significance and impact on clinical outcome
    • P. Vaupel, and A. Mayer Hypoxia in cancer: significance and impact on clinical outcome Cancer Metastasis Rev 26 2007 225 239
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 225-239
    • Vaupel, P.1    Mayer, A.2
  • 82
    • 46749143345 scopus 로고    scopus 로고
    • Molecular imaging of hypoxia
    • K.A. Krohn, J.M. Link, and R.P. Mason Molecular imaging of hypoxia J Nucl Med 49 Suppl. 2 2008 129S 148S
    • (2008) J Nucl Med , vol.49 , pp. 129S-148S
    • Krohn, K.A.1    Link, J.M.2    Mason, R.P.3
  • 83
    • 0031597439 scopus 로고    scopus 로고
    • Studies of 99mTc-BnAO (HL-91): A non-nitroaromatic compound for hypoxic cell detection
    • X. Zhang, T. Melo, J.R. Ballinger, and A.M. Rauth Studies of 99mTc-BnAO (HL-91): a non-nitroaromatic compound for hypoxic cell detection Int J Radiat Oncol Biol Phys 42 1998 737 740
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 737-740
    • Zhang, X.1    Melo, T.2    Ballinger, J.R.3    Rauth, A.M.4
  • 84
    • 0031793733 scopus 로고    scopus 로고
    • Preclinical evaluation of the novel hypoxic marker 99mTc-HL91 (Prognox) in murine and xenograft systems in vivo
    • D.J. Honess, S.A. Hill, and D.R. Collingridge Preclinical evaluation of the novel hypoxic marker 99mTc-HL91 (Prognox) in murine and xenograft systems in vivo Int J Radiat Oncol Biol Phys 42 1998 731 735
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 731-735
    • Honess, D.J.1    Hill, S.A.2    Collingridge, D.R.3
  • 85
    • 34848893337 scopus 로고    scopus 로고
    • Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole
    • S.T. Lee, and A.M. Scott Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole Semin Nucl Med 37 2007 451 461
    • (2007) Semin Nucl Med , vol.37 , pp. 451-461
    • Lee, S.T.1    Scott, A.M.2
  • 86
    • 84873714403 scopus 로고    scopus 로고
    • Angiogenesis inhibitors in the treatment of epithelial ovarian cancer
    • E.S. Han, M. Wakabayashi, and L. Leong Angiogenesis inhibitors in the treatment of epithelial ovarian cancer Curr Treat Options Oncol 14 2013 22 33
    • (2013) Curr Treat Options Oncol , vol.14 , pp. 22-33
    • Han, E.S.1    Wakabayashi, M.2    Leong, L.3
  • 87
    • 49649123154 scopus 로고    scopus 로고
    • BIBF 1120: Triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy
    • F. Hilberg, G.J. Roth, and M. Krssak BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy Cancer Res 68 2008 4774 4782
    • (2008) Cancer Res , vol.68 , pp. 4774-4782
    • Hilberg, F.1    Roth, G.J.2    Krssak, M.3
  • 88
    • 79956012866 scopus 로고    scopus 로고
    • Assessing the activity of cediranib, a VEGFR-2/3 tyrosine kinase inhibitor, against VEGFR-1 and members of the structurally related PDGFR family
    • S.R. Brave, K. Ratcliffe, and Z. Wilson Assessing the activity of cediranib, a VEGFR-2/3 tyrosine kinase inhibitor, against VEGFR-1 and members of the structurally related PDGFR family Mol Cancer Ther 10 2011 861 873
    • (2011) Mol Cancer Ther , vol.10 , pp. 861-873
    • Brave, S.R.1    Ratcliffe, K.2    Wilson, Z.3
  • 89
    • 84885594084 scopus 로고    scopus 로고
    • Randomized, double-blind, phase III trial of pazopanib versus placebo in women who have not progressed after first-line chemotherapy for advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (AEOC): Results of an international Intergroup trial (AGO-OVAR16)
    • [Abstract LBA 5503]
    • A. du Bois, A. Floquet, and J. Weon Randomized, double-blind, phase III trial of pazopanib versus placebo in women who have not progressed after first-line chemotherapy for advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (AEOC): Results of an international Intergroup trial (AGO-OVAR16) J Clin Oncol 31 2013 [Abstract LBA 5503]
    • (2013) J Clin Oncol , vol.31
    • Du Bois, A.1    Floquet, A.2    Weon, J.3
  • 91
    • 84863012011 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer
    • B.Y. Karlan, A.M. Oza, and G.E. Richardson Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer J Clin Oncol 30 2012 362 371
    • (2012) J Clin Oncol , vol.30 , pp. 362-371
    • Karlan, B.Y.1    Oza, A.M.2    Richardson, G.E.3
  • 92
    • 84903517779 scopus 로고    scopus 로고
    • Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): A randomised, multicentre, double-blind, placebo-controlled phase 3 trial
    • B.J. Monk, A. Poveda, and I. Vergote Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial Lancet Oncol 15 2014 799 808
    • (2014) Lancet Oncol , vol.15 , pp. 799-808
    • Monk, B.J.1    Poveda, A.2    Vergote, I.3
  • 93
    • 83255192931 scopus 로고    scopus 로고
    • Activity of cabozantinib (XL184) in advanced ovarian cancer patients (pts): Results from a phase II randomized discontinuation trial (RDT)
    • [Abstract 5008]
    • R.J. Buckanovich, R. Berger, and A. Sella Activity of cabozantinib (XL184) in advanced ovarian cancer patients (pts): results from a phase II randomized discontinuation trial (RDT) J Clin Oncol 29 2011 [Abstract 5008]
    • (2011) J Clin Oncol , vol.29
    • Buckanovich, R.J.1    Berger, R.2    Sella, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.