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Volumn 124, Issue 5, 2009, Pages 1045-1053

Functional significance of VEGFR-2 on ovarian cancer cells

Author keywords

Angio genesis; Ovarian carcinoma; VEGFR

Indexed keywords

CRK ASSOCIATED SUBSTRATE PROTEIN; MONOCLONAL ANTIBODY DC101; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; MONOCLONAL ANTIBODY;

EID: 58749097443     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24028     Document Type: Article
Times cited : (126)

References (43)
  • 2
    • 12944315020 scopus 로고    scopus 로고
    • Epithelial ovarian cancer: Prevention, diagnosis, and treatment
    • Partridge EE. Barnes MN. Epithelial ovarian cancer: prevention, diagnosis, and treatment. CA Cancer J Clin 1999;49;297-320.
    • (1999) CA Cancer J Clin , vol.49 , pp. 297-320
    • Partridge, E.E.1    Barnes, M.N.2
  • 3
    • 0043240182 scopus 로고    scopus 로고
    • Ovarian cancer: Strategies for overcoming resistance to chemotherapy
    • Agarwal R, Kaye SB. Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 2003;3:502-16.
    • (2003) Nat Rev Cancer , vol.3 , pp. 502-516
    • Agarwal, R.1    Kaye, S.B.2
  • 4
    • 18844432114 scopus 로고    scopus 로고
    • Ozols RF. Treatment goals in ovarian cancer. Int J Gynecol Cancer 20O5;15Suppl 1:3-11.
    • Ozols RF. Treatment goals in ovarian cancer. Int J Gynecol Cancer 20O5;15Suppl 1:3-11.
  • 5
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak HF. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 2002;20:4368-80.
    • (2002) J Clin Oncol , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 6
    • 28444476260 scopus 로고    scopus 로고
    • Angiogenic inhibitors: A new therapeutic strategy in oncology
    • Gasparini G, Longo R, Toi M, Ferrara N. Angiogenic inhibitors: a new therapeutic strategy in oncology. Nat Clin Pract Oncol 2005;2:562-77.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 562-577
    • Gasparini, G.1    Longo, R.2    Toi, M.3    Ferrara, N.4
  • 8
    • 0028153737 scopus 로고
    • Vascular permeability factor gene expression in normal and neoplastic human ovaries
    • Olson TA, Mohanraj D, Carson LF, Ramakrishnan S. Vascular permeability factor gene expression in normal and neoplastic human ovaries. Cancer Res 1994;54:276-80.
    • (1994) Cancer Res , vol.54 , pp. 276-280
    • Olson, T.A.1    Mohanraj, D.2    Carson, L.F.3    Ramakrishnan, S.4
  • 11
    • 0030817612 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) in epithelial ovarian neoplasms: Correlation with clinicopa-thology and patient survival, and analvsis of serum VEGF levels
    • Yaraamoto S, Konishi I, Mandai M, Kuroda H, Komatsu T, Nanbu K, Sakahara H, Mori T. Expression of vascular endothelial growth factor (VEGF) in epithelial ovarian neoplasms: correlation with clinicopa-thology and patient survival, and analvsis of serum VEGF levels. Br J Cancer 1997;76:1221-7.
    • (1997) Br J Cancer , vol.76 , pp. 1221-1227
    • Yaraamoto, S.1    Konishi, I.2    Mandai, M.3    Kuroda, H.4    Komatsu, T.5    Nanbu, K.6    Sakahara, H.7    Mori, T.8
  • 12
    • 0032944081 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonraalignant disease
    • Kraft A, Weindel K, Ochs A, Marth C, Zmija J, Schumacher P, Unger C, Mamie D, Gastl G. Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonraalignant disease. Cancer 1999;85:178-87.
    • (1999) Cancer , vol.85 , pp. 178-187
    • Kraft, A.1    Weindel, K.2    Ochs, A.3    Marth, C.4    Zmija, J.5    Schumacher, P.6    Unger, C.7    Mamie, D.8    Gastl, G.9
  • 14
    • 0032787305 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and its two receptors (VEGF-Rl-Fltl and VEGF-R2-Flkl/ KDR) in non-small cell lung carcinomas (NSCLCs): Correlation with angiogenesis and survival
    • Decaussin M, Sartelet H, Robert C, Moro D, Claraz C, Brambilla C, Brambilla E. Expression of vascular endothelial growth factor (VEGF) and its two receptors (VEGF-Rl-Fltl and VEGF-R2-Flkl/ KDR) in non-small cell lung carcinomas (NSCLCs): correlation with angiogenesis and survival. J Pathol 1999;188:369-77.
    • (1999) J Pathol , vol.188 , pp. 369-377
    • Decaussin, M.1    Sartelet, H.2    Robert, C.3    Moro, D.4    Claraz, C.5    Brambilla, C.6    Brambilla, E.7
  • 16
    • 0035885932 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors
    • Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood 2001;98:1904-13.
    • (2001) Blood , vol.98 , pp. 1904-1913
    • Masood, R.1    Cai, J.2    Zheng, T.3    Smith, D.L.4    Hinton, D.R.5    Gill, P.S.6
  • 17
    • 33747498714 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma
    • Wu Y, Hooper AT, Zhong Z, Witte L, Bohlen P, Rafii S, Hicklin DJ. The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma. Int J Cancer 2006; 119:1519-29.
    • (2006) Int J Cancer , vol.119 , pp. 1519-1529
    • Wu, Y.1    Hooper, A.T.2    Zhong, Z.3    Witte, L.4    Bohlen, P.5    Rafii, S.6    Hicklin, D.J.7
  • 19
    • 0033083962 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies
    • Bellamy WT, Richter L, Frutiger Y, Grogan TM. Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies. Cancer Res 1999;59:728-33.
    • (1999) Cancer Res , vol.59 , pp. 728-733
    • Bellamy, W.T.1    Richter, L.2    Frutiger, Y.3    Grogan, T.M.4
  • 22
    • 7244236494 scopus 로고    scopus 로고
    • Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo
    • Wang ES, Teruya-Feldstein J, Wu Y, Zhu Z, Hicklin DJ, Moore MA. Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo. Blood 2004;104:2893-902.
    • (2004) Blood , vol.104 , pp. 2893-2902
    • Wang, E.S.1    Teruya-Feldstein, J.2    Wu, Y.3    Zhu, Z.4    Hicklin, D.J.5    Moore, M.A.6
  • 23
    • 4444324696 scopus 로고    scopus 로고
    • VEGF, VEGFRs expressions and activated. STATs in ovarian epithelial carcinoma
    • Chen H, Ye D, Xie X, Chen B, Lu W. VEGF, VEGFRs expressions and activated. STATs in ovarian epithelial carcinoma. Gynecol Oncol 2004;94:630-5.
    • (2004) Gynecol Oncol , vol.94 , pp. 630-635
    • Chen, H.1    Ye, D.2    Xie, X.3    Chen, B.4    Lu, W.5
  • 24
    • 4444378842 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma
    • Nishida N, Yano H, Komai K, Nishida T, Kamura T, Kojiro M. Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma. Cancer 2004; 101:1364 - 74.
    • (2004) Cancer , vol.101 , pp. 1364-1374
    • Nishida, N.1    Yano, H.2    Komai, K.3    Nishida, T.4    Kamura, T.5    Kojiro, M.6
  • 25
    • 0029929046 scopus 로고    scopus 로고
    • Strong expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in ovarian borderline and malignant neoplasms
    • Abu-Jawdeh GM, Faix JD, Niloff J, Tognazzi K, Manseau E, Dvorak HF, Brown LF. Strong expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in ovarian borderline and malignant neoplasms. Lab Invest 1996;74:1105-15.
    • (1996) Lab Invest , vol.74 , pp. 1105-1115
    • Abu-Jawdeh, G.M.1    Faix, J.D.2    Niloff, J.3    Tognazzi, K.4    Manseau, E.5    Dvorak, H.F.6    Brown, L.F.7
  • 26
    • 27644479545 scopus 로고    scopus 로고
    • Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors
    • Thaker PH, Yazici S, Nilsson MB, Yokoi K, Tsan RZ, He J, Kim SJ, Fidler IJ, Sood AK. Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors. Clin Cancer Res 2005;11:4923-33.
    • (2005) Clin Cancer Res , vol.11 , pp. 4923-4933
    • Thaker, P.H.1    Yazici, S.2    Nilsson, M.B.3    Yokoi, K.4    Tsan, R.Z.5    He, J.6    Kim, S.J.7    Fidler, I.J.8    Sood, A.K.9
  • 28
    • 3042717667 scopus 로고    scopus 로고
    • Regulation of integrin-mediated cellular responses through assetnblv of a CAS/Crk scaffold
    • Chodniewicz D, Klemke RL. Regulation of integrin-mediated cellular responses through assetnblv of a CAS/Crk scaffold. Biochim Biophys Acta 2004;1692;63-76.
    • (2004) Biochim Biophys Acta , vol.1692 , pp. 63-76
    • Chodniewicz, D.1    Klemke, R.L.2
  • 29
    • 0032559562 scopus 로고    scopus 로고
    • Klemke RL, Leng J, Molander R, Brooks PC, Vuori K. Cheresh DA. CAS/Crk coupling serves as a molecular switch for induction of cell migration. J Cell Biol 1998;140:961-72.
    • Klemke RL, Leng J, Molander R, Brooks PC, Vuori K. Cheresh DA. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J Cell Biol 1998;140:961-72.
  • 31
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor. KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
    • Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM. Expression of vascular endothelial growth factor and its receptor. KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 1995;55:3964-8.
    • (1995) Cancer Res , vol.55 , pp. 3964-3968
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 32
    • 0032146088 scopus 로고    scopus 로고
    • Expression of two angiogenic factors, vascular endothelial growth factor and platelet-derived endothelial cell growth factor in human pancreatic cancer, and its relationship to angiogenesis
    • Fujimoto K, Hosotani R, Wada M, Lee JU, Koshiba T, Miyamoto Y, Tsuji S, Nakajima S, Doi R, Imamura M. Expression of two angiogenic factors, vascular endothelial growth factor and platelet-derived endothelial cell growth factor in human pancreatic cancer, and its relationship to angiogenesis. Eur J Cancer 1998;34:1439-47.
    • (1998) Eur J Cancer , vol.34 , pp. 1439-1447
    • Fujimoto, K.1    Hosotani, R.2    Wada, M.3    Lee, J.U.4    Koshiba, T.5    Miyamoto, Y.6    Tsuji, S.7    Nakajima, S.8    Doi, R.9    Imamura, M.10
  • 34
    • 0034772250 scopus 로고    scopus 로고
    • Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480
    • George DJ, Halabi S, Shepard TF, Vogelzang NJ, Hayes DF, Small EJ, Kantoff PW. Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clin Cancer Res 2001;7:1932-6.
    • (2001) Clin Cancer Res , vol.7 , pp. 1932-1936
    • George, D.J.1    Halabi, S.2    Shepard, T.F.3    Vogelzang, N.J.4    Hayes, D.F.5    Small, E.J.6    Kantoff, P.W.7
  • 35
    • 0141721698 scopus 로고    scopus 로고
    • Gorski DH, Leal AD, Goydos JS. Differential expression of vascular endothelial growth factor-A isoforms at different stages of melanoma\ progression. J Am Coll Surg 2003;197:408-18.
    • Gorski DH, Leal AD, Goydos JS. Differential expression of vascular endothelial growth factor-A isoforms at different stages of melanoma\ progression. J Am Coll Surg 2003;197:408-18.
  • 36
    • 0030921126 scopus 로고    scopus 로고
    • The expression of vascular endothelial growth factor and transforming growth factor-beta associates with angiogenesis in epithelial ovarian cancer
    • Nakanishi Y, Kodama J, Yoshinouchi M, Tokumo K, Kamimura S, Okuda H, Kudo T. The expression of vascular endothelial growth factor and transforming growth factor-beta associates with angiogenesis in epithelial ovarian cancer. Int J Gynecol Pathol 1997;16:256-62.
    • (1997) Int J Gynecol Pathol , vol.16 , pp. 256-262
    • Nakanishi, Y.1    Kodama, J.2    Yoshinouchi, M.3    Tokumo, K.4    Kamimura, S.5    Okuda, H.6    Kudo, T.7
  • 37
  • 38
    • 0242331176 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF
    • Endo A, Fukuhara S, Masuda M, Ohmori T, Mochizuki N. Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF. J Recept Signal Transduct Res 2003;23:239-54.
    • (2003) J Recept Signal Transduct Res , vol.23 , pp. 239-254
    • Endo, A.1    Fukuhara, S.2    Masuda, M.3    Ohmori, T.4    Mochizuki, N.5
  • 39
    • 38449123004 scopus 로고    scopus 로고
    • Activation of the FAK-src molecular scaffolds and pl30Cas-JNK signaling cascades by alpha 1-integrins during colon cancer cell invasion
    • Van Slambrouck S, Grijelmo C, De Wever O, Bruyneel E, Emami S, Gespach C, Steelant WF. Activation of the FAK-src molecular scaffolds and pl30Cas-JNK signaling cascades by alpha 1-integrins during colon cancer cell invasion. Tnt J Oncol 2007;31:1501-8.
    • (2007) Tnt J Oncol , vol.31 , pp. 1501-1508
    • Van Slambrouck, S.1    Grijelmo, C.2    De Wever, O.3    Bruyneel, E.4    Emami, S.5    Gespach, C.6    Steelant, W.F.7
  • 40
    • 33746721000 scopus 로고    scopus 로고
    • Immunolocalizations of VEGF, its receptors fit-1, KDR and. TGF-beta's in epithelial ovarian tumors
    • Tnan S, Vatansever S, Celik-Ozenci C, Sanci M, Dicle N, Demir R. Immunolocalizations of VEGF, its receptors fit-1, KDR and. TGF-beta's in epithelial ovarian tumors. Histol Histopathol 2006;21:1055-64.
    • (2006) Histol Histopathol , vol.21 , pp. 1055-1064
    • Tnan, S.1    Vatansever, S.2    Celik-Ozenci, C.3    Sanci, M.4    Dicle, N.5    Demir, R.6
  • 43
    • 62549135184 scopus 로고    scopus 로고
    • Camidge DR, Eckhardt SG, Diab S, Gore L, Chow L, O'Bryant C, Temmer E, Ervin-Haynes A, Kate T, Fox F, Cohen RB. A phase I dose-escalation study of weekly IMC-1121B, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR2) IgG 1 monoclonal antibody (Mab). in patients (pts) with advanced cancer [abstract #3032]. J Clin Oncol 2006;24(18S)
    • Camidge DR, Eckhardt SG, Diab S, Gore L, Chow L, O'Bryant C, Temmer E, Ervin-Haynes A, Kate T, Fox F, Cohen RB. A phase I dose-escalation study of weekly IMC-1121B, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR2) IgG 1 monoclonal antibody (Mab). in patients (pts) with advanced cancer [abstract #3032]. J Clin Oncol 2006;24(18S)


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