Membrane active phenylalanine conjugated lipophilic norspermidine derivatives with selective antibacterial activity

Journal of Medicinal Chemistry

Volumn 57, Issue 22, 2014, Pages 9409-9423

  Konai, Mohini M ^a   Ghosh, Chandradhish ^a   Yarlagadda, Venkateswarlu ^a   Samaddar, Sandip ^a   Haldar, Jayanta ^a  

^a JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; AROMATIC AMINO ACID; COLISTIN; SPERMIDINE DERIVATIVE; VANCOMYCIN; BETA LACTAM; MICELLE; NORSPERMIDINE; PHENYLALANINE; SPERMIDINE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; CELL VIABILITY; CRITICAL MICELLE CONCENTRATION; HEMOLYSIS; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; VANCOMYCIN RESISTANT ENTEROCOCCUS; WILD TYPE; ANALOGS AND DERIVATIVES; BACTERIAL INFECTIONS; CHEMISTRY; CONFORMATION; DRUG DESIGN; DRUG EFFECTS; ENTEROCOCCUS FAECIUM; HUMAN; KINETICS; MICELLE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PLASMA; SERUM; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BETA-LACTAMS; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS FAECIUM; HUMANS; KINETICS; KLEBSIELLA PNEUMONIAE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICELLES; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; PHENYLALANINE; PLASMA; SERUM; SPERMIDINE; TETRAZOLIUM SALTS; THIAZOLES; VANCOMYCIN;

EID: 84913593686     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm5013566     Document Type: Article

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