메뉴 건너뛰기




Volumn 76, Issue 6, 2014, Pages 769-783

Neuroimaging biomarkers for Parkinson disease: Facts and fantasy

Author keywords

[No Author keywords available]

Indexed keywords

6 FLUORODOPAMINE F 18; BIOLOGICAL MARKER;

EID: 84913582942     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.24291     Document Type: Article
Times cited : (40)

References (80)
  • 1
    • 84873564460 scopus 로고    scopus 로고
    • Binding of the radioligand SIL23 to alpha-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease imaging agent
    • Bagchi DP, Yu L, Perlmutter JS, et al. Binding of the radioligand SIL23 to alpha-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease imaging agent. PLoS One 2013;8:e55031.
    • (2013) Plos One , vol.8 , pp. e55031
    • Bagchi, D.P.1    Yu, L.2    Perlmutter, J.S.3
  • 2
    • 0242302336 scopus 로고    scopus 로고
    • Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease
    • suppl 1
    • Brooks DJ, Frey KA, Marek KL, et al. Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease. Exp Neurol 2003;184(suppl 1):S68-S79.
    • (2003) Exp Neurol , vol.184 , pp. S68-S79
    • Brooks, D.J.1    Frey, K.A.2    Marek, K.L.3
  • 3
    • 0030659028 scopus 로고    scopus 로고
    • MPTP induces dystonia and parkinsonism: Clues to the pathophysiology of dystonia
    • Perlmutter JS, Tempel LW, Black KJ, et al. MPTP induces dystonia and parkinsonism: clues to the pathophysiology of dystonia. Neurology 1997;49:1432-1438.
    • (1997) Neurology , vol.49 , pp. 1432-1438
    • Perlmutter, J.S.1    Tempel, L.W.2    Black, K.J.3
  • 4
    • 0026793873 scopus 로고
    • Parkinson's disease in twins studied with 18F-dopa and positron emission tomography
    • Burn DJ, Mark MH, Playford ED, et al. Parkinson's disease in twins studied with 18F-dopa and positron emission tomography. Neurology 1992;42:1894-1900.
    • (1992) Neurology , vol.42 , pp. 1894-1900
    • Burn, D.J.1    Mark, M.H.2    Playford, E.D.3
  • 5
    • 34548278879 scopus 로고    scopus 로고
    • Progressive changes of preand post-synaptic dopaminergic biomarkers in conscious MPTPtreated cynomolgus monkeys measured by positron emission tomography
    • Nagai Y, Obayashi S, Ando K, et al. Progressive changes of preand post-synaptic dopaminergic biomarkers in conscious MPTPtreated cynomolgus monkeys measured by positron emission tomography. Synapse 2007;61:809-819.
    • (2007) Synapse , vol.61 , pp. 809-819
    • Nagai, Y.1    Obayashi, S.2    Ando, K.3
  • 6
    • 0023696415 scopus 로고
    • Asymptomatic striatal dopamine depletion: PET scans in unilateral MPTP monkeys
    • Guttman M, Yong VW, Kim SU, et al. Asymptomatic striatal dopamine depletion: PET scans in unilateral MPTP monkeys. Synapse 1988;2:469-473.
    • (1988) Synapse , vol.2 , pp. 469-473
    • Guttman, M.1    Yong, V.W.2    Kim, S.U.3
  • 7
    • 70249090695 scopus 로고    scopus 로고
    • Negative predictive value of SPECT with I123 ioflupane in movement disorders
    • (reply) [in Spanish]
    • Serrano VJ, Garcia BL, Duran BC, et al. Negative predictive value of SPECT with I123 ioflupane in movement disorders (reply) [in Spanish]. Rev Esp Med Nucl 2009;28:267-268.
    • (2009) Rev Esp Med Nucl , vol.28 , pp. 267-268
    • Serrano, V.J.1    Garcia, B.L.2    Duran, B.C.3
  • 8
    • 84864803421 scopus 로고    scopus 로고
    • Low nigrostriatal reserve for motor parkinsonism in nonhuman primates
    • Tabbal SD, Tian L, Karimi M, et al. Low nigrostriatal reserve for motor parkinsonism in nonhuman primates. Exp Neurol 2012;237: 355-362.
    • (2012) Exp Neurol , vol.237 , pp. 355-362
    • Tabbal, S.D.1    Tian, L.2    Karimi, M.3
  • 9
    • 84876479290 scopus 로고    scopus 로고
    • Validation of nigrostriatal positron emission tomography measures: Critical limits
    • Karimi M, Tian L, Brown CA, et al. Validation of nigrostriatal positron emission tomography measures: critical limits. Ann Neurol 2013;73:390-396.
    • (2013) Ann Neurol , vol.73 , pp. 390-396
    • Karimi, M.1    Tian, L.2    Brown, C.A.3
  • 10
    • 75749128636 scopus 로고    scopus 로고
    • Abnormalities in metabolic network activity precede the onset of motor symptoms in Parkinson's disease
    • Tang CC, Poston KL, Dhawan V, et al. Abnormalities in metabolic network activity precede the onset of motor symptoms in Parkinson's disease. J Neurosci 2010;30:1049-1056.
    • (2010) J Neurosci , vol.30 , pp. 1049-1056
    • Tang, C.C.1    Poston, K.L.2    Dhawan, V.3
  • 11
    • 0033603794 scopus 로고    scopus 로고
    • Users' guides to the medical literature: XIX. Applying clinical trial results. A. How to use an article measuring the effect of an intervention on surrogate end points. Evidence-Based Medicine Working Group
    • Bucher HC, Guyatt GH, Cook DJ, et al. Users' guides to the medical literature: XIX. Applying clinical trial results. A. How to use an article measuring the effect of an intervention on surrogate end points. Evidence-Based Medicine Working Group. JAMA 1999; 282:771-778.
    • (1999) Jama , vol.282 , pp. 771-778
    • Bucher, H.C.1    Guyatt, G.H.2    Cook, D.J.3
  • 12
    • 0030268577 scopus 로고    scopus 로고
    • Surrogate end points in clinical trials: Are we being misled?
    • Fleming TR, DeMets DL. Surrogate end points in clinical trials: are we being misled? Ann Intern Med 1996;125:605-613.
    • (1996) Ann Intern Med , vol.125 , pp. 605-613
    • Fleming, T.R.1    DeMets, D.L.2
  • 13
    • 0037132607 scopus 로고    scopus 로고
    • Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT)
    • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). JAMA 2002;288:2998-3007.
    • (2002) Jama , vol.288 , pp. 2998-3007
  • 14
    • 0026011647 scopus 로고
    • Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial
    • Echt DS, Liebson PR, Mitchell LB, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med 1991;324:781-788.
    • (1991) N Engl J Med , vol.324 , pp. 781-788
    • Echt, D.S.1    Liebson, P.R.2    Mitchell, L.B.3
  • 15
    • 0024158956 scopus 로고
    • Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: The CAPS
    • Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS. Am J Cardiol 1988;61:501-509.
    • (1988) Am J Cardiol , vol.61 , pp. 501-509
  • 16
    • 18244404294 scopus 로고    scopus 로고
    • Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using Doppler embolic signal detection: The Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial
    • Markus HS, Droste DW, Kaps M, et al. Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using Doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial. Circulation 2005;111:2233-2240.
    • (2005) Circulation , vol.111 , pp. 2233-2240
    • Markus, H.S.1    Droste, D.W.2    Kaps, M.3
  • 17
    • 19744378296 scopus 로고    scopus 로고
    • Levodopa and the progression of Parkinson's disease
    • Fahn S, Oakes D, Shoulson I, et al. Levodopa and the progression of Parkinson's disease. N Engl J Med 2004;351:2498-2508.
    • (2004) N Engl J Med , vol.351 , pp. 2498-2508
    • Fahn, S.1    Oakes, D.2    Shoulson, I.3
  • 18
    • 0037785449 scopus 로고    scopus 로고
    • Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study
    • Whone AL, Watts RL, Stoessl AJ, et al. Slower progression of Parkinson's disease with ropinirole versus levodopa: the REAL-PET study. Ann Neurol 2003;54:93-101.
    • (2003) Ann Neurol , vol.54 , pp. 93-101
    • Whone, A.L.1    Watts, R.L.2    Stoessl, A.J.3
  • 19
    • 19944432710 scopus 로고    scopus 로고
    • The role of radiotracer imaging in Parkinson disease
    • Ravina B, Eidelberg D, Ahlskog JE, et al. The role of radiotracer imaging in Parkinson disease. Neurology 2005;64:208-215.
    • (2005) Neurology , vol.64 , pp. 208-215
    • Ravina, B.1    Eidelberg, D.2    Ahlskog, J.E.3
  • 20
    • 33644833272 scopus 로고    scopus 로고
    • Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
    • Lang AE, Gill S, Patel NK, et al. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol 2006;59:459-466.
    • (2006) Ann Neurol , vol.59 , pp. 459-466
    • Lang, A.E.1    Gill, S.2    Patel, N.K.3
  • 22
    • 0035826089 scopus 로고    scopus 로고
    • Transplantation of embryonic dopamine neurons for severe Parkinson's disease
    • Freed CR, Greene PE, Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 2001;344:710-718.
    • (2001) N Engl J Med , vol.344 , pp. 710-718
    • Freed, C.R.1    Greene, P.E.2    Breeze, R.E.3
  • 23
    • 0027219169 scopus 로고
    • Correlation of striatal fluorodopa uptake in the MPTP monkey with dopaminergic indices
    • Pate BD, Kawamata T, Yamada T, et al. Correlation of striatal fluorodopa uptake in the MPTP monkey with dopaminergic indices. Ann Neurol 1993;34:331-338.
    • (1993) Ann Neurol , vol.34 , pp. 331-338
    • Pate, B.D.1    Kawamata, T.2    Yamada, T.3
  • 24
    • 0027327049 scopus 로고
    • Human positron emission tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels
    • Snow BJ, Tooyama I, McGeer EG, et al. Human positron emission tomographic [18F]fluorodopa studies correlate with dopamine cell counts and levels. Ann Neurol 1993;34:324-330.
    • (1993) Ann Neurol , vol.34 , pp. 324-330
    • Snow, B.J.1    Tooyama, I.2    McGeer, E.G.3
  • 25
    • 34548846637 scopus 로고    scopus 로고
    • Quantitative [(123)I]FP-CIT pinhole SPECT imaging predicts striatal dopamine levels, but not number of nigral neurons in different mouse models of Parkinson's disease
    • Alvarez-Fischer D, Blessmann G, Trosowski C, et al. Quantitative [(123)I]FP-CIT pinhole SPECT imaging predicts striatal dopamine levels, but not number of nigral neurons in different mouse models of Parkinson's disease. Neuroimage 2007;38:5-12.
    • (2007) Neuroimage , vol.38 , pp. 5-12
    • Alvarez-Fischer, D.1    Blessmann, G.2    Trosowski, C.3
  • 26
    • 33746419587 scopus 로고    scopus 로고
    • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced acute transient dystonia in monkeys associated with low striatal dopamine
    • Tabbal SD, Mink JW, Antenor JA, et al. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced acute transient dystonia in monkeys associated with low striatal dopamine. Neuroscience 2006;141:1281-1287.
    • (2006) Neuroscience , vol.141 , pp. 1281-1287
    • Tabbal, S.D.1    Mink, J.W.2    Antenor, J.A.3
  • 27
    • 0029664364 scopus 로고    scopus 로고
    • [123I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease
    • Marek KL, Seibyl JP, Zoghbi SS, et al. [123I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease. Neurology 1996;46:231-237.
    • (1996) Neurology , vol.46 , pp. 231-237
    • Marek, K.L.1    Seibyl, J.P.2    Zoghbi, S.S.3
  • 28
    • 84880932230 scopus 로고    scopus 로고
    • Disease duration and the integrity of the nigrostriatal system in Parkinson's disease
    • Kordower JH, Olanow CW, Dodiya HB, et al. Disease duration and the integrity of the nigrostriatal system in Parkinson's disease. Brain 2013;136:2419-2431.
    • (2013) Brain , vol.136 , pp. 2419-2431
    • Kordower, J.H.1    Olanow, C.W.2    Dodiya, H.B.3
  • 29
    • 84863115493 scopus 로고    scopus 로고
    • No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease
    • Tian L, Karimi M, Loftin SK, et al. No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease. PLoS One 2012;7:e31439.
    • (2012) Plos One , vol.7 , pp. e31439
    • Tian, L.1    Karimi, M.2    Loftin, S.K.3
  • 30
    • 84903272267 scopus 로고    scopus 로고
    • In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment
    • Tian L, Karimi M, Brown CA, et al. In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment. Brain Res 2014; 1571:49-60.
    • (2014) Brain Res , vol.1571 , pp. 49-60
    • Tian, L.1    Karimi, M.2    Brown, C.A.3
  • 31
    • 84890123415 scopus 로고    scopus 로고
    • Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaques
    • Brown CA, Karimi MK, Tian L, et al. Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaques. Ann Neurol 2013;74:602-610.
    • (2013) Ann Neurol , vol.74 , pp. 602-610
    • Brown, C.A.1    Karimi, M.K.2    Tian, L.3
  • 32
    • 15544391275 scopus 로고    scopus 로고
    • Parkinson's disease: In vivo assessment of disease progression using positron emission tomography
    • Au WL, Adams JR, Troiano AR, Stoessl AJ. Parkinson's disease: in vivo assessment of disease progression using positron emission tomography. Brain Res Mol Brain Res 2005;134:24-33.
    • (2005) Brain Res Mol Brain Res , vol.134 , pp. 24-33
    • Au, W.L.1    Adams, J.R.2    Troiano, A.R.3    Stoessl, A.J.4
  • 33
    • 0035849532 scopus 로고    scopus 로고
    • Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD
    • Guttman M, Stewart D, Hussey D, et al. Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD. Neurology 2001;56:1559-1564.
    • (2001) Neurology , vol.56 , pp. 1559-1564
    • Guttman, M.1    Stewart, D.2    Hussey, D.3
  • 34
    • 78649504565 scopus 로고    scopus 로고
    • Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTPtreated monkeys
    • Fernagut PO, Li Q, Dovero S, et al. Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTPtreated monkeys. PLoS One 2010;5:e14053.
    • (2010) Plos One , vol.5 , pp. e14053
    • Fernagut, P.O.1    Li, Q.2    Dovero, S.3
  • 35
    • 0033408426 scopus 로고    scopus 로고
    • Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [123I]beta-CIT
    • Innis RB, Marek KL, Sheff K, et al. Effect of treatment with L-dopa/carbidopa or L-selegiline on striatal dopamine transporter SPECT imaging with [123I]beta-CIT. Mov Disord 1999;14:436-442.
    • (1999) Mov Disord , vol.14 , pp. 436-442
    • Innis, R.B.1    Marek, K.L.2    Sheff, K.3
  • 36
    • 33645972896 scopus 로고    scopus 로고
    • [18F]FDOPA PET as an endophenotype for Parkinson's disease linkage studies
    • Racette BA, Good L, Antenor JA, et al. [18F]FDOPA PET as an endophenotype for Parkinson's disease linkage studies. Am J Med Genet B Neuropsychiatr Genet 2006;141:245-249.
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 , pp. 245-249
    • Racette, B.A.1    Good, L.2    Antenor, J.A.3
  • 37
    • 20344362679 scopus 로고    scopus 로고
    • [18F]FDOPA PET and clinical features in parkinsonism due to manganism
    • Racette BA, Antenor JA, McGee-Minnich L, et al. [18F]FDOPA PET and clinical features in parkinsonism due to manganism. Mov Disord 2005;20:492-496.
    • (2005) Mov Disord , vol.20 , pp. 492-496
    • Racette, B.A.1    Antenor, J.A.2    McGee-Minnich, L.3
  • 38
    • 84858595211 scopus 로고    scopus 로고
    • Reduced uptake of FDOPA PET in end-stage liver disease with elevated manganese levels
    • Criswell SR, Perlmutter JS, Crippin JS, et al. Reduced uptake of FDOPA PET in end-stage liver disease with elevated manganese levels. Arch Neurol 2012;69:394-397.
    • (2012) Arch Neurol , vol.69 , pp. 394-397
    • Criswell, S.R.1    Perlmutter, J.S.2    Crippin, J.S.3
  • 39
    • 0024452083 scopus 로고
    • Positron emission tomography in manganese intoxication
    • Wolters EC, Huang CC, Clark C, et al. Positron emission tomography in manganese intoxication. Ann Neurol 1989;26:647-651.
    • (1989) Ann Neurol , vol.26 , pp. 647-651
    • Wolters, E.C.1    Huang, C.C.2    Clark, C.3
  • 40
    • 0030847395 scopus 로고    scopus 로고
    • Differentiating between multiple system atrophy and Parkinson's disease by positron emission tomography with 18F-dopa and 18F-FDG
    • Otsuka M, Kuwabara Y, Ichiya Y, et al. Differentiating between multiple system atrophy and Parkinson's disease by positron emission tomography with 18F-dopa and 18F-FDG. Ann Nucl Med 1997;11:251-257.
    • (1997) Ann Nucl Med , vol.11 , pp. 251-257
    • Otsuka, M.1    Kuwabara, Y.2    Ichiya, Y.3
  • 41
    • 79954669576 scopus 로고    scopus 로고
    • Reduced uptake of [18F]FDOPA PET in asymptomatic welders with occupational manganese exposure
    • Criswell SR, Perlmutter JS, Videen TO, et al. Reduced uptake of [18F]FDOPA PET in asymptomatic welders with occupational manganese exposure. Neurology 2011;76:1296-1301.
    • (2011) Neurology , vol.76 , pp. 1296-1301
    • Criswell, S.R.1    Perlmutter, J.S.2    Videen, T.O.3
  • 42
    • 0025695511 scopus 로고
    • The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease
    • Leenders KL, Salmon EP, Tyrrell P, et al. The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease. Arch Neurol 1990;47:1290-1298.
    • (1990) Arch Neurol , vol.47 , pp. 1290-1298
    • Leenders, K.L.1    Salmon, E.P.2    Tyrrell, P.3
  • 43
    • 0027296568 scopus 로고
    • Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease
    • Frost JJ, Rosier AJ, Reich SG, et al. Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease. Ann Neurol 1993;34:423-431.
    • (1993) Ann Neurol , vol.34 , pp. 423-431
    • Frost, J.J.1    Rosier, A.J.2    Reich, S.G.3
  • 44
    • 0025091036 scopus 로고
    • The metabolic anatomy of Parkinson's disease: Complementary [18F]fluorodeoxyglucose and [18F]fluorodopa positron emission tomographic studies
    • Eidelberg D, Moeller JR, Dhawan V, et al. The metabolic anatomy of Parkinson's disease: complementary [18F]fluorodeoxyglucose and [18F]fluorodopa positron emission tomographic studies. Mov Disord 1990;5:203-213.
    • (1990) Mov Disord , vol.5 , pp. 203-213
    • Eidelberg, D.1    Moeller, J.R.2    Dhawan, V.3
  • 45
    • 0028868355 scopus 로고
    • Complementary positron emission tomographic studies of the striatal dopaminergic system in Parkinson's disease
    • Antonini A, Vontobel P, Psylla M, et al. Complementary positron emission tomographic studies of the striatal dopaminergic system in Parkinson's disease. Arch Neurol 1995;52:1183-1190.
    • (1995) Arch Neurol , vol.52 , pp. 1183-1190
    • Antonini, A.1    Vontobel, P.2    Psylla, M.3
  • 46
    • 0029873012 scopus 로고    scopus 로고
    • Clinical significance of striatal DOPA decarboxylase activity in Parkinson's disease
    • Ishikawa T, Dhawan V, Chaly T, et al. Clinical significance of striatal DOPA decarboxylase activity in Parkinson's disease. J Nucl Med 1996;37:216-222.
    • (1996) J Nucl Med , vol.37 , pp. 216-222
    • Ishikawa, T.1    Dhawan, V.2    Chaly, T.3
  • 47
    • 0029981856 scopus 로고    scopus 로고
    • An [18F]dopa-PET and clinical study of the rate of the progression in Parkinson's disease
    • Morrish PK, Sawle GV, Brooks DJ. An [18F]dopa-PET and clinical study of the rate of the progression in Parkinson's disease. Brain 1996;119:585-591.
    • (1996) Brain , vol.119 , pp. 585-591
    • Morrish, P.K.1    Sawle, G.V.2    Brooks, D.J.3
  • 48
    • 33747348188 scopus 로고    scopus 로고
    • Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease
    • Bohnen NI, Albin RL, Koeppe RA, et al. Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease. J Cereb Blood Flow Metab 2006;26:1198-1212.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1198-1212
    • Bohnen, N.I.1    Albin, R.L.2    Koeppe, R.A.3
  • 49
    • 0029094141 scopus 로고
    • Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease
    • Seibyl JP, Marek KL, Quinlan D, et al. Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease. Ann Neurol 1995;38:589-598.
    • (1995) Ann Neurol , vol.38 , pp. 589-598
    • Seibyl, J.P.1    Marek, K.L.2    Quinlan, D.3
  • 50
    • 0028271363 scopus 로고
    • Separating Parkinson's disease from normality. Discriminant function analysis of fluorodopa F 18 positron emission tomography data
    • Sawle GV, Playford ED, Burn DJ, et al. Separating Parkinson's disease from normality. Discriminant function analysis of fluorodopa F 18 positron emission tomography data. Arch Neurol 1994;51: 237-243.
    • (1994) Arch Neurol , vol.51 , pp. 237-243
    • Sawle, G.V.1    Playford, E.D.2    Burn, D.J.3
  • 51
    • 57049114326 scopus 로고    scopus 로고
    • Predictive value of nigrostriatal dysfunction in isolated tremor: A clinical and SPECT study
    • Ceravolo R, Antonini A, Volterrani D, et al. Predictive value of nigrostriatal dysfunction in isolated tremor: a clinical and SPECT study. Mov Disord 2008;23:2049-2054.
    • (2008) Mov Disord , vol.23 , pp. 2049-2054
    • Ceravolo, R.1    Antonini, A.2    Volterrani, D.3
  • 52
    • 84901312035 scopus 로고    scopus 로고
    • Diagnoses behind patients with hard-to-classify tremor and normal DaTSPECT: A clinical follow up study
    • Menendez-Gonzalez M, Tavares F, Zeidan N, et al. Diagnoses behind patients with hard-to-classify tremor and normal DaTSPECT: a clinical follow up study. Front Aging Neurosci 2014;6: 56.
    • (2014) Front Aging Neurosci , vol.6 , pp. 56
    • Menendez-Gonzalez, M.1    Tavares, F.2    Zeidan, N.3
  • 53
    • 4043084987 scopus 로고    scopus 로고
    • (123I) beta-CIT and singlephoton emission computed tomographic imaging vs clinical evaluation in Parkinsonian syndrome: Unmasking an early diagnosis
    • Jennings DL, Seibyl JP, Oakes D, et al. (123I) beta-CIT and singlephoton emission computed tomographic imaging vs clinical evaluation in Parkinsonian syndrome: unmasking an early diagnosis. Arch Neurol 2004;61:1224-1229.
    • (2004) Arch Neurol , vol.61 , pp. 1224-1229
    • Jennings, D.L.1    Seibyl, J.P.2    Oakes, D.3
  • 54
    • 84860800663 scopus 로고    scopus 로고
    • Role of DaTSCAN and clinical diagnosis in Parkinson disease
    • Fuente-Fernandez R. Role of DaTSCAN and clinical diagnosis in Parkinson disease. Neurology 2012;78:696-701.
    • (2012) Neurology , vol.78 , pp. 696-701
    • Fuente-Fernandez, R.1
  • 55
    • 45049084405 scopus 로고    scopus 로고
    • The cost effectiveness of 123I-FP-CIT SPECT imaging in patients with an uncertain clinical diagnosis of parkinsonism
    • Van Laere K, Everaert L, Annemans L, et al. The cost effectiveness of 123I-FP-CIT SPECT imaging in patients with an uncertain clinical diagnosis of parkinsonism. Eur J Nucl Med Mol Imaging 2008; 35:1367-1376.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 1367-1376
    • Van Laere, K.1    Everaert, L.2    Annemans, L.3
  • 56
    • 0242288107 scopus 로고    scopus 로고
    • Dopamine transporter imaging and SPECT in diagnostic work-up of Parkinson's disease: A decision-analytic approach
    • suppl 7
    • Dodel RC, Hoffken H, Moller JC, et al. Dopamine transporter imaging and SPECT in diagnostic work-up of Parkinson's disease: a decision-analytic approach. Mov Disord 2003;18(suppl 7):S52-S62.
    • (2003) Mov Disord , vol.18 , pp. S52-S62
    • Dodel, R.C.1    Hoffken, H.2    Moller, J.C.3
  • 57
    • 58249086346 scopus 로고    scopus 로고
    • Radionuclide scanning to diagnose Parkinson disease: Is it cost-effective?
    • Stoessl AJ. Radionuclide scanning to diagnose Parkinson disease: is it cost-effective? Nat Clin Pract Neurol 2009;5:10-11.
    • (2009) Nat Clin Pract Neurol , vol.5 , pp. 10-11
    • Stoessl, A.J.1
  • 58
    • 84860829158 scopus 로고    scopus 로고
    • To scan or not to scan: DaT is the question
    • Perlmutter JS, Eidelberg D. To scan or not to scan: DaT is the question. Neurology 2012;78:688-689.
    • (2012) Neurology , vol.78 , pp. 688-689
    • Perlmutter, J.S.1    Eidelberg, D.2
  • 59
    • 0028300346 scopus 로고
    • Biochemical and fluorodopa positron emission tomographic findings in an asymptomatic carrier of the gene for dopa-responsive dystonia
    • Takahashi H, Levine RA, Galloway MP, et al. Biochemical and fluorodopa positron emission tomographic findings in an asymptomatic carrier of the gene for dopa-responsive dystonia. Ann Neurol 1994;35:354-356.
    • (1994) Ann Neurol , vol.35 , pp. 354-356
    • Takahashi, H.1    Levine, R.A.2    Galloway, M.P.3
  • 60
    • 2942538455 scopus 로고    scopus 로고
    • Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies
    • O'Brien JT, Colloby S, Fenwick J, et al. Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies. Arch Neurol 2004;61:919-925.
    • (2004) Arch Neurol , vol.61 , pp. 919-925
    • O'Brien, J.T.1    Colloby, S.2    Fenwick, J.3
  • 61
    • 33847638908 scopus 로고    scopus 로고
    • Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: A phase III, multicentre study
    • McKeith I, O'Brien J, Walker Z, et al. Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study. Lancet Neurol 2007;6:305-313.
    • (2007) Lancet Neurol , vol.6 , pp. 305-313
    • McKeith, I.1    O'Brien, J.2    Walker, Z.3
  • 62
    • 74149085154 scopus 로고    scopus 로고
    • The epidemiology of dementia associated with Parkinson disease
    • Aarsland D, Kurz MW. The epidemiology of dementia associated with Parkinson disease. J Neurol Sci 2010;289:18-22.
    • (2010) J Neurol Sci , vol.289 , pp. 18-22
    • Aarsland, D.1    Kurz, M.W.2
  • 63
    • 41149173996 scopus 로고    scopus 로고
    • The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years
    • Hely MA, Reid WG, Adena MA, et al. The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years. Mov Disord 2008;23:837-844.
    • (2008) Mov Disord , vol.23 , pp. 837-844
    • Hely, M.A.1    Reid, W.G.2    Adena, M.A.3
  • 64
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B
    • Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann Neurol 2004;55:306-319.
    • (2004) Ann Neurol , vol.55 , pp. 306-319
    • Klunk, W.E.1    Engler, H.2    Nordberg, A.3
  • 65
    • 33747048954 scopus 로고    scopus 로고
    • [11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
    • Mintun MA, LaRossa GN, Sheline YI, et al. [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology 2006;67:446-452.
    • (2006) Neurology , vol.67 , pp. 446-452
    • Mintun, M.A.1    LaRossa, G.N.2    Sheline, Y.I.3
  • 66
    • 73549092137 scopus 로고    scopus 로고
    • Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease
    • Morris JC, Roe CM, Grant EA, et al. Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease. Arch Neurol 2009;66:1469-1475.
    • (2009) Arch Neurol , vol.66 , pp. 1469-1475
    • Morris, J.C.1    Roe, C.M.2    Grant, E.A.3
  • 67
    • 84865529158 scopus 로고    scopus 로고
    • Clinical and biomarker changes in dominantly inherited Alzheimer's disease
    • Bateman RJ, Xiong C, Benzinger TL, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 2012;367:795-804.
    • (2012) N Engl J Med , vol.367 , pp. 795-804
    • Bateman, R.J.1    Xiong, C.2    Benzinger, T.L.3
  • 68
    • 56749185181 scopus 로고    scopus 로고
    • Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography
    • Edison P, Rowe CC, Rinne JO, et al. Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography. J Neurol Neurosurg Psychiatry 2008;79:1331-1338.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 1331-1338
    • Edison, P.1    Rowe, C.C.2    Rinne, J.O.3
  • 69
    • 62149140954 scopus 로고    scopus 로고
    • Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics
    • Maetzler W, Liepelt I, Reimold M, et al. Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics. Neurobiol Dis 2009;34:107-112.
    • (2009) Neurobiol Dis , vol.34 , pp. 107-112
    • Maetzler, W.1    Liepelt, I.2    Reimold, M.3
  • 70
    • 54049100454 scopus 로고    scopus 로고
    • Imaging amyloid deposition in Lewy body diseases
    • Gomperts SN, Rentz DM, Moran E, et al. Imaging amyloid deposition in Lewy body diseases. Neurology 2008;71:903-910.
    • (2008) Neurology , vol.71 , pp. 903-910
    • Gomperts, S.N.1    Rentz, D.M.2    Moran, E.3
  • 71
    • 78349250530 scopus 로고    scopus 로고
    • Amyloid imaging of Lewy body-associated disorders
    • Foster ER, Campbell MC, Burack MA, et al. Amyloid imaging of Lewy body-associated disorders. Mov Disord 2010;15:2516-2523.
    • (2010) Mov Disord , vol.15 , pp. 2516-2523
    • Foster, E.R.1    Campbell, M.C.2    Burack, M.A.3
  • 72
    • 34948819200 scopus 로고    scopus 로고
    • Imaging of amyloid burden and distribution in cerebral amyloid angiopathy
    • Johnson KA, Gregas M, Becker JA, et al. Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol 2007;62:229-234.
    • (2007) Ann Neurol , vol.62 , pp. 229-234
    • Johnson, K.A.1    Gregas, M.2    Becker, J.A.3
  • 73
    • 84899971919 scopus 로고    scopus 로고
    • Diagnostic utility of amyloid PET in cerebral amyloid angiopathy-related symptomatic intracerebral hemorrhage
    • Baron JC, Farid K, Dolan E, et al. Diagnostic utility of amyloid PET in cerebral amyloid angiopathy-related symptomatic intracerebral hemorrhage. J Cereb Blood Flow Metab 2014;34:753-758.
    • (2014) J Cereb Blood Flow Metab , vol.34 , pp. 753-758
    • Baron, J.C.1    Farid, K.2    Dolan, E.3
  • 74
    • 74049124939 scopus 로고    scopus 로고
    • In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia
    • Burack MA, Hartlein J, Flores HP, et al. In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia. Neurology 2010;74:77-84.
    • (2010) Neurology , vol.74 , pp. 77-84
    • Burack, M.A.1    Hartlein, J.2    Flores, H.P.3
  • 75
    • 84867390597 scopus 로고    scopus 로고
    • Pathologic accumulation of alpha-synuclein and Abeta in Parkinson disease patients with dementia
    • Kotzbauer PT, Cairns NJ, Campbell MC, et al. Pathologic accumulation of alpha-synuclein and Abeta in Parkinson disease patients with dementia. Arch Neurol 2012;69:1326-1331.
    • (2012) Arch Neurol , vol.69 , pp. 1326-1331
    • Kotzbauer, P.T.1    Cairns, N.J.2    Campbell, M.C.3
  • 76
    • 73549123897 scopus 로고    scopus 로고
    • Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: A case report
    • Cairns NJ, Ikonomovic MD, Benzinger T, et al. Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report. Arch Neurol 2009;66:1557-1562.
    • (2009) Arch Neurol , vol.66 , pp. 1557-1562
    • Cairns, N.J.1    Ikonomovic, M.D.2    Benzinger, T.3
  • 77
    • 84884569192 scopus 로고    scopus 로고
    • Principal component analysis of PiB distribution in Parkinson and Alzheimer diseases
    • Campbell MC, Markham J, Flores H, et al. Principal component analysis of PiB distribution in Parkinson and Alzheimer diseases. Neurology 2013;81:520-527.
    • (2013) Neurology , vol.81 , pp. 520-527
    • Campbell, M.C.1    Markham, J.2    Flores, H.3
  • 78
    • 84873647470 scopus 로고    scopus 로고
    • Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia
    • Gomperts SN, Locascio JJ, Rentz D, et al. Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia. Neurology 2013;80:85-91.
    • (2013) Neurology , vol.80 , pp. 85-91
    • Gomperts, S.N.1    Locascio, J.J.2    Rentz, D.3
  • 79
    • 77957220702 scopus 로고    scopus 로고
    • CSF amyloid {beta} 1-42 predicts cognitive decline in Parkinson disease
    • Siderowf A, Xie SX, Hurtig H, et al. CSF amyloid {beta} 1-42 predicts cognitive decline in Parkinson disease. Neurology 2010;75:1055-1061.
    • (2010) Neurology , vol.75 , pp. 1055-1061
    • Siderowf, A.1    Xie, S.X.2    Hurtig, H.3
  • 80
    • 84920482878 scopus 로고    scopus 로고
    • Correlation between decreased CSF a-synuclein and Ab1-42 in Parkinson disease
    • Epub ahead of print
    • Buddhala C, Campbell MC, Perlmutter JS, Kotzbauer PT. Correlation between decreased CSF a-synuclein and Ab1-42 in Parkinson disease. Neurobiol Aging 2014. pii: S0197-4580(14)00512-0. doi: 10.1016/j.neurobiolaging.2014.07.043. [Epub ahead of print]
    • (2014) Neurobiol Aging
    • Buddhala, C.1    Campbell, M.C.2    Perlmutter, J.S.3    Kotzbauer, P.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.