Determinants of vitamin D levels in Italian children and adolescents: A longitudinal evaluation of cholecalciferol supplementation versus the improvement of factors influencing 25(OH)D status

International Journal of Endocrinology

Volumn 2014, Issue , 2014, Pages

  Stagi, Stefano ^a   Pelosi, Paola ^a   Strano, Massimo ^b   Poggi, Giovanni ^a   Manoni, Cristina ^a   De Martino, Maurizio ^a   Seminara, Salvatore ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b SANTA MARIA ANNUNZIATA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; COLECALCIFEROL; VITAMIN D;

ADOLESCENT; ARTICLE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; INTERVENTION STUDY; ITALIAN (CITIZEN); LIFESTYLE MODIFICATION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; NORMAL VALUE; OUTCOME ASSESSMENT; PHYSICAL ACTIVITY; RISK FACTOR; SEASONAL VARIATION; TREATMENT DURATION; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION;

EID: 84913582849     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2014/583039     Document Type: Article

References (48)

1. McKenna M. J., Differences in vitamin D status between countries in young adults and the elderly. The American Journal of Medicine 1992 93 1 69 77 10.1016/0002-9343(92)90682-2 2-s2.0-0026653787
2. Lips P., Duong T., Oleksik A., Black D., Cummings S., Cox D., Nickelsen T., A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. The Journal of Clinical Endocrinology and Metabolism 2001 86 3 1212 1221 10.1210/jc.86.3.1212 2-s2.0-0035048979
3. Holick M. F., Vitamin D deficiency. New England Journal of Medicine 2007 357 3 266 281 10.1056/NEJMra070553 2-s2.0-34447514029
4. Stagi S., Cavalli L., Bertini F., de Martino M., Matucci Cerinic M., Brandi M. L., Falcini F., Vitamin D levels in children, adolescents, and young adults with juvenile-onset systemic lupus erythematosus: a cross-sectional study. Lupus 2014 23 10 1059 1065 10.1177/0961203314532564
5. Stagi S., Bertini F., Cavalli L., Matucci Cerinic M., Brandi M. L., Falcini F., Determinants of vitamin D levels in children, adolescents, and young adults with juvenile idiopathic arthritis. Journal of Rheumatology 2014
6. Gerdhem P., Ringsberg K. A. M., Obrant K. J., Akesson K., Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women. Osteoporosis International 2005 16 11 1425 1431 10.1007/s00198-005-1860-1 2-s2.0-27544456849
7. Lippi G., Montagnana M., Targher G., Vitamin D deficiency among Italian children. Canadian Medical Association Journal 2007 177 12 1529 1530 10.1503/cmaj.1070102 2-s2.0-37049030197
8. Vierucci F., Del Pistoia M., Fanos M., Gori M., Carlone G., Erba P., Massimetti G., Federico G., Saggese G., Vitamin D status and predictors of hypovitaminosis D in Italian children and adolescents: a cross-sectional study. European Journal of Pediatrics 2013 172 12 1607 1617 10.1007/s00431-013-2119-z 2-s2.0-84890427565
9. Vierucci F., del Pistoia M., Fanos M., Erba P., Saggese G., Prevalence of hypovitaminosis D and predictors of vitamin D status in Italian healthy adolescents. Acta Veterinaria Scandinavica 2014 40 54 63 10.1186/1824-7288-40-54 2-s2.0-84901729989
10. Bellone S., Esposito S., Giglione E., Genoni G., Fiorito C., Petri A., Bona G., Prodam F., Vitamin D levels in a paediatric population of normal weight and obese subjects. Journal of Endocrinological Investigation 2014
11. Jones G., Strugnell S. A., DeLuca H. F., Current understanding of the molecular actions of vitamin D. Physiological Reviews 1998 78 4 1193 1231 2-s2.0-0031755168
12. Arnson Y., Amital H., Shoenfeld Y., Vitamin D and autoimmunity: new aetiological and therapeutic considerations. Annals of the Rheumatic Diseases 2007 66 9 1137 1142 10.1136/ard.2007.069831 2-s2.0-34548150136
13. Stagi S., Bertini F., Rigante D., Falcini F., Vitamin D levels and effects of vitamin D replacement in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. International Journal of Pediatric Otorhinolaryngology 2014 78 6 964 968 10.1016/j.ijporl.2014.03.026 2-s2.0-84899954212
14. Holick M. F., Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. The American Journal of Clinical Nutrition 2004 80 6 1678S 1688S 2-s2.0-16544381338
15. Visser M., Deeg D. J., Lips P., Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. Journal of Clinical Endocrinology and Metabolism 2003 88 12 5766 5772 10.1210/jc.2003-030604 2-s2.0-0346732368
16. Rovner A. J., O'Brien K. O., Hypovitaminosis D among healthy children in the United States: a review of the current evidence. Archives of Pediatrics and Adolescent Medicine 2008 162 6 513 519 10.1001/archpedi.162.6.513 2-s2.0-44649090758
17. Heaney R. P., Lessons for nutritional science from vitamin D. The American Journal of Clinical Nutrition 1999 69 5 825 826 2-s2.0-0032913016
18. Wagner C. L., Greer F. R., American Academy of Pediatrics Section on Breastfeeding; American Academy of Pediatrics Committee on Nutrition, Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics 2008 122 5 1142 1152
19. Gartner L. M., Greer F. R., Black L. S., Lawrence R. A., Naylor A. J., O'Hare D., Schanler R. J., Eidelman A. I., Krebs N. F., Baker R. D. Jr., Heyman M. B., Jaksic T., Lifshitz F., Prevention of rickets and vitamin D deficiency: new guidelines for vitamin D intake. Pediatrics 2003 111 4 908 910 10.1542/peds.111.4.908 2-s2.0-0037383521
20. Stagi S., Lapi E., Gambineri E., Manoni C., Genuardi M., Colarusso G., Conti C., Chiarelli F., De Martino M., Azzari C., Bone density and metabolism in subjects with microdeletion of chromosome 22q11 (del22q11). European Journal of Endocrinology 2010 163 2 329 337 10.1530/EJE-10-0167 2-s2.0-77955394161
21. Webb A. R., Pilbeam C., Hanafin N., Holick M. F., An evaluation of the relative contributions of exposure to sunlight and of diet to the circulating concentrations of 25-hydroxyvitamin D in an elderly nursing home population in Boston. The American Journal of Clinical Nutrition 1990 51 6 1075 1081 2-s2.0-0025372715
22. Absoud M., Cummins C., Lim M. J., Wassmer E., Shaw N., Prevalence and predictors of vitamin D insufficiency in children: a great britain population based study. PLoS ONE 2011 6 7 e22179 10.1371/journal.pone.0022179 2-s2.0-79960670102
23. Al-Daghri N. M., Al-Attas O. S., Alokail M. S., Alkharfy K. M., El-Kholie E., Yousef M., Al-Othman A., Al-Saleh Y., Sabico S., Kumar S., Chrousos G. P., Increased vitamin D supplementation recommended during summer season in the gulf region: a counterintuitive seasonal effect in vitamin D levels in adult, overweight and obese Middle Eastern residents. Clinical Endocrinology 2012 76 3 346 350 10.1111/j.1365-2265.2011.04219.x 2-s2.0-84863011591
24. Balk S. J., Ultraviolet radiation: a hazard to children and adolescents. Council on Environmental Health, Section on Dermatology. Pediatrics 2011 127 3 588 597 10.1542/peds.2010-3501
25. Cacciari E., Milani S., Balsamo A., Spada E., Bona G., Cavallo L., Cerutti F., Gargantini L., Greggio N., Tonini G., Cicognani A., Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr). Journal of Endocrinological Investigation 2006 29 7 581 593 10.1007/BF03344156 2-s2.0-33748998206
26. Stagi S., Galli L., Cecchi C., Chiappini E., Losi S., Gattinara C. G., Gabiano C., Tovo P. A., Bernardi S., Chiarelli F., De Martino M., Final height in patients perinatally infected with the human immunodeficiency virus. Hormone Research in Paediatrics 2010 74 3 165 171 10.1159/000281018 2-s2.0-78049476817
27. Tanner J. M., Whitehouse R. H., Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Archives of Disease in Childhood 1976 51 3 170 179 10.1136/adc.51.3.170 2-s2.0-0017261757
28. Salvini S., Parpinel M., Gnagnarella P., Maisonneuve P., Turrini A., Dati di composizione degli alimenti per studi epidemiologici in Italia 1998 Milano, Italy Istituto Europeo di Oncologia
29. Callaghan A. L., Moy R. J. D., Booth I. W., Debelle G., Shaw N. J., Incidence of symptomatic vitamin D deficiency. Archives of Disease in Childhood 2006 91 7 606 607 10.1136/adc.2006.095075 2-s2.0-33745775633
30. Gessner B. D., Plotnik J., Muth P. T., 25-Hydroxyvitamin D levels among healthy children in Alaska. Journal of Pediatrics 2003 143 4 434 437 10.1067/S0022-3476(03)00410-4 2-s2.0-0242267077
31. Gordon C. M., Feldman H. A., Sinclair L., Williams A. L., Kleinman P. K., Perez-Rossello J., Cox J. E., Prevalence of vitamin D deficiency among healthy infants and toddlers. Archives of Pediatrics and Adolescent Medicine 2008 162 6 505 512 10.1001/archpedi.162.6.505 2-s2.0-42549138539
32. Raimundo F. V., Lang M. A. B., Scopel L., Marcondes N. A., Araújo M. G. A., Faulhaber G. A. M., Furlanetto T. W., Effect of fat on serum 25-hydroxyvitamin D levels after a single oral dose of vitamin D in young healthy adults: a double-blind randomized placebo-controlled study. European Journal of Nutrition 2014 10.1007/s00394-014-0718-8 2-s2.0-84901516109
33. Raimundo F. V., Faulhaber G. A. M., Menegatti P. K., Marques L. D. S., Furlanetto T. W., Effect of high- versus low-fat meal on serum 25-hydroxyvitamin D levels after a single oral dose of vitamin D: a single-blind, parallel, randomized trial. International Journal of Endocrinology 2011 2011 5 809069 10.1155/2011/809069 2-s2.0-84855598846
34. Mose F. H., Vase H., Larsen T., Kancir A. S. P., Kosierkiewic R., Jonczy B., Hansen A. B., Oczachowska-Kulik A. E., Thomsen I. M., Bech J. N., Pedersen E. B., Cardiovascular effects of cholecalciferol treatment in dialysis patients-a randomized controlled trial. BMC Nephrology 2014 15 1, article 50 10.1186/1471-2369-15-50 2-s2.0-84899089999
35. Dalbeni A., Scaturro G., Degan M., Minuz P., Delva P., Effects of six months of vitamin D supplementation in patients with heart failure: a randomized double-blind controlled trial. Nutrition, Metabolism and Cardiovascular Diseases 2014 24 8 861 868 10.1016/j.numecd.2014.02.015 2-s2.0-84898715851
36. Shroff R., Wan M., Gullett A., Ledermann S., Shute R., Knott C., Wells D., Aitkenhead H., Manickavasagar B., van't Hoff W., Rees L., Ergocalciferol supplementation in children with CKD delays the onset of secondary hyperparathyroidism: a randomized trial. Clinical Journal of the American Society of Nephrology 2012 7 2 216 223 10.2215/CJN.04760511 2-s2.0-84857188798
37. Wykes C., Arasaretnam A., O'Driscoll S., Farnham L., Moniz C., Rees D. C., Vitamin D deficiency and its correction in children with sickle cell anaemia. Annals of Hematology 2014
38. Pappa H. M., Mitchell P. D., Jiang H., Kassiff S., Filip-Dhima R., DiFabio D., Quinn N., Lawton R. C., Bronzwaer M., Koenen M., Gordon C. M., Maintenance of optimal vitamin D status in children and adolescents with inflammatory bowel disease: a randomized clinical trial comparing two regimens. Journal of Clinical Endocrinology & Metabolism 2014 99 9 3408 3417 10.1210/jc.2013-4218
39. Lewis R. D., Laing E. M., Hill Gallant K. M., Hall D. B., McCabe G. P., Hausman D. B., Martin B. R., Warden S. J., Peacock M., Weaver C. M., A randomized trial of vitamin D3 supplementation in children: dose-Response effects on vitamin D metabolites and calcium absorption. Journal of Clinical Endocrinology and Metabolism 2013 98 12 4816 4825 10.1210/jc.2013-2728 2-s2.0-84889868253
40. Cosenza L., Pezzella V., Nocerino R., Di Costanzo M., Coruzzo A., Passariello A., Leone L., Savoia M., Del Puente A., Esposito A., Terrin G., Canani R. B., Calcium and vitamin D intakes in children: a randomized controlled trial. BMC Pediatrics 2013 13 1, article 86 10.1186/1471-2431-13-86 2-s2.0-84878007669
41. Marrone G., Rosso I., Moretti R., Valent F., Romanello C., Is vitamin D status known among children living in Northern Italy? European Journal of Nutrition 2012 51 2 143 149 10.1007/s00394-011-0200-9 2-s2.0-84860682585
42. Maguire J. L., Lebovic G., Kandasamy S., Khovratovich M., Mamdani M., Birken C. S., Parkin P. C., The relationship between cow's milk and stores of vitamin D and iron in early childhood. Pediatrics 2013 131 1 e144 e151 10.1542/peds.2012-1793 2-s2.0-84872860219
43. El Hayek J., Egeland G., Weiler H., Vitamin D status of Inuit preschoolers reflects season and vitamin D intake. Journal of Nutrition 2010 140 10 1839 1845 10.3945/jn.110.124644 2-s2.0-77958128997
44. Schmid A., Walther B., Natural vitamin D content in animal products. Advances in Nutrition 2013 4 4 453 462 10.3945/an.113.003780 2-s2.0-84891712285
45. Al-Othman A., Al-Musharaf S., Al-Daghri N. M., Krishnaswamy S., Yusuf D. S., Alkharfy K. M., Al-Saleh Y., Al-Attas O. S., Alokail M. S., Moharram O., Sabico S., Chrousos G. P., Effect of physical activity and sun exposure on vitamin D status of Saudi children and adolescents. BMC Pediatrics 2012 12, article 92 10.1186/1471-2431-12-92 2-s2.0-84863204507
46. Dahifar H., Faraji A., Ghorbani A., Yassobi S., Impact of dietary and lifestyle on vitamin D in healthy student girls aged 11-15 years. Journal of Medical Investigation 2006 53 3-4 204 208 10.2152/jmi.53.204 2-s2.0-33750303828
47. Dong Y., Pollock N., Stallmann-Jorgensen I. S., Gutin B., Lan L., Chen T. C., Keeton D., Petty K., Holick M. F., Zhu H., Low 25-hydroxyvitamin D levels in adolescents: race, season, adiposity, physical activity, and fitness. Pediatrics 2010 125 6 1104 1111 10.1542/peds.2009-2055 2-s2.0-77953047816
48. Houghton L. A., Gray A. R., Szymlek-Gay E. A., Heath A.-L. M., Ferguson E. L., Vitamin D-Fortified milk achieves the targeted serum 25-hydroxyvitamin D concentration without affecting that of parathyroid hormone in New Zealand toddlers. Journal of Nutrition 2011 141 10 1840 1846 10.3945/jn.111.145052 2-s2.0-81055137600