메뉴 건너뛰기




Volumn 746, Issue , 2015, Pages 63-69

Antiplatelet activity of loureirin A by attenuating Akt phosphorylation: In vitro studies

Author keywords

Aggregation; Loureirin A; PI3K Akt; Platelet; Spreading

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTITHROMBOCYTIC AGENT; CHALCONE DERIVATIVE; DRAGON'S BLOOD; FIBRINOGEN; IMMOBILIZED PROTEIN; LOUREIRIN A; PADGEM PROTEIN; PLANT EXTRACT; PROTEIN KINASE B; THROMBIN;

EID: 84913570671     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.10.059     Document Type: Article
Times cited : (30)

References (28)
  • 1
    • 4444269330 scopus 로고    scopus 로고
    • Impaired platelet responses to thrombin and collagen in AKT-1-deficient mice
    • J. Chen, S. De, D.S. Damron, W.S. Chen, N. Hay, and T.V. Byzova Impaired platelet responses to thrombin and collagen in AKT-1-deficient mice Blood 104 2004 1703 1710
    • (2004) Blood , vol.104 , pp. 1703-1710
    • Chen, J.1    De, S.2    Damron, D.S.3    Chen, W.S.4    Hay, N.5    Byzova, T.V.6
  • 3
    • 33751187650 scopus 로고    scopus 로고
    • Continuous signaling via PI3K isoforms beta and gamma is required for platelet ADP receptor function in dynamic thrombus stabilization
    • J.M.E.M. Cosemans, L.C.A. Munnix, R. Wetzker, R. Heller, S.P. Jackson, and J.W.M. Heemskerk Continuous signaling via PI3K isoforms beta and gamma is required for platelet ADP receptor function in dynamic thrombus stabilization Blood 108 2006 3045 3052
    • (2006) Blood , vol.108 , pp. 3045-3052
    • Cosemans, J.M.E.M.1    Munnix, L.C.A.2    Wetzker, R.3    Heller, R.4    Jackson, S.P.5    Heemskerk, J.W.M.6
  • 4
    • 79951711056 scopus 로고    scopus 로고
    • Modulation of platelet function and signaling by flavonoids
    • M. El Haouari, and J.A. Rosado Modulation of platelet function and signaling by flavonoids Mini Rev. Med. Chem. 11 2011 131 142
    • (2011) Mini Rev. Med. Chem. , vol.11 , pp. 131-142
    • El Haouari, M.1    Rosado, J.A.2
  • 5
    • 70450284458 scopus 로고    scopus 로고
    • Simultaneous quantification of five major constituents in stems of Dracaena plants and related medicinal preparations from China and Vietnam by HPLC-DAD
    • L.L. Fan, P.F. Tu, H.B. Chen, and S.Q. Cai Simultaneous quantification of five major constituents in stems of Dracaena plants and related medicinal preparations from China and Vietnam by HPLC-DAD Biomed. Chromatogr. 23 2009 1191 1200
    • (2009) Biomed. Chromatogr. , vol.23 , pp. 1191-1200
    • Fan, L.L.1    Tu, P.F.2    Chen, H.B.3    Cai, S.Q.4
  • 7
    • 37549000584 scopus 로고    scopus 로고
    • Dragons blood: Botany, chemistry and therapeutic uses
    • D. Gupta, B. Bleakley, and R.K. Gupta Dragons blood: botany, chemistry and therapeutic uses J. Ethnopharmacol. 115 2008 361 380
    • (2008) J. Ethnopharmacol. , vol.115 , pp. 361-380
    • Gupta, D.1    Bleakley, B.2    Gupta, R.K.3
  • 8
    • 2342486055 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinases and the regulation of platelet function
    • S.P. Jackson, C.L. Yap, and K.E. Anderson Phosphoinositide 3-kinases and the regulation of platelet function Biochem. Soc. Trans. 32 2004 387 392
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 387-392
    • Jackson, S.P.1    Yap, C.L.2    Anderson, K.E.3
  • 9
    • 84867013588 scopus 로고    scopus 로고
    • Advances in monitoring of aspirin therapy
    • M. Lordkipanidze Advances in monitoring of aspirin therapy Platelets 23 2012 526 536
    • (2012) Platelets , vol.23 , pp. 526-536
    • Lordkipanidze, M.1
  • 10
    • 77952900972 scopus 로고    scopus 로고
    • Mechanisms of oral bacteria-induced platelet activation
    • A. McNicol, and S.J. Israels Mechanisms of oral bacteria-induced platelet activation Can. J. Physiol. Pharmacol. 88 2010 510 524
    • (2010) Can. J. Physiol. Pharmacol. , vol.88 , pp. 510-524
    • McNicol, A.1    Israels, S.J.2
  • 11
    • 84882407357 scopus 로고    scopus 로고
    • Flow cytometric assessment of agonist-induced P-selectin expression as a measure of platelet quality in stored platelet concentrates
    • R.A. Middelburg, M. Roest, J. Ham, M. Coccoris, J.J. Zwaginga, and P.F. van der Meer Flow cytometric assessment of agonist-induced P-selectin expression as a measure of platelet quality in stored platelet concentrates Transfusion 53 2013 1780 1787
    • (2013) Transfusion , vol.53 , pp. 1780-1787
    • Middelburg, R.A.1    Roest, M.2    Ham, J.3    Coccoris, M.4    Zwaginga, J.J.5    Van Der Meer, P.F.6
  • 12
    • 84873671033 scopus 로고    scopus 로고
    • Dual regulation of glycogen synthase kinase 3 (GSK3)alpha/beta by protein kinase C (PKC)alpha and Akt promotes thrombin-mediated integrin alphaIIbbeta3 activation and granule secretion in platelets
    • S.F. Moore, M.T. van den Bosch, R.W. Hunter, K. Sakamoto, A.W. Poole, and I. Hers Dual regulation of glycogen synthase kinase 3 (GSK3)alpha/beta by protein kinase C (PKC)alpha and Akt promotes thrombin-mediated integrin alphaIIbbeta3 activation and granule secretion in platelets J. Biol. Chem. 288 2013 3918 3928
    • (2013) J. Biol. Chem. , vol.288 , pp. 3918-3928
    • Moore, S.F.1    Van Den Bosch, M.T.2    Hunter, R.W.3    Sakamoto, K.4    Poole, A.W.5    Hers, I.6
  • 13
    • 84865447255 scopus 로고    scopus 로고
    • ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3beta
    • K.A. OBrien, T.K. Gartner, N. Hay, and X. Du ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3beta Arterioscler. Thromb. Vasc. Biol. 32 2012 2232 2240
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 2232-2240
    • Obrien, K.A.1    Gartner, T.K.2    Hay, N.3    Du, X.4
  • 14
    • 80054119619 scopus 로고    scopus 로고
    • An important role for Akt3 in platelet activation and thrombosis
    • K.A. OBrien, A. Stojanovic-Terpo, N. Hay, and X. Du An important role for Akt3 in platelet activation and thrombosis Blood 118 2011 4215 4223
    • (2011) Blood , vol.118 , pp. 4215-4223
    • Obrien, K.A.1    Stojanovic-Terpo, A.2    Hay, N.3    Du, X.4
  • 15
    • 84872124879 scopus 로고    scopus 로고
    • Dual roles of quercetin in platelets: Phosphoinositide-3-kinase and MAP kinases inhibition, and cAMP-dependent vasodilator-stimulated phosphoprotein stimulation
    • W.J. Oh, M. Endale, S.C. Park, J.Y. Cho, and M.H. Rhee Dual roles of quercetin in platelets: phosphoinositide-3-kinase and MAP kinases inhibition, and cAMP-dependent vasodilator-stimulated phosphoprotein stimulation Evi. Based Complement. Alternat. Med. 2012 2012 485262
    • (2012) Evi. Based Complement. Alternat. Med. , vol.2012 , pp. 485262
    • Oh, W.J.1    Endale, M.2    Park, S.C.3    Cho, J.Y.4    Rhee, M.H.5
  • 17
    • 0036851876 scopus 로고    scopus 로고
    • Platelets in atherothrombosis
    • Z.M. Ruggeri Platelets in atherothrombosis Nat. Med. 8 2002 1227 1234
    • (2002) Nat. Med. , vol.8 , pp. 1227-1234
    • Ruggeri, Z.M.1
  • 18
    • 4444264392 scopus 로고    scopus 로고
    • Integrins: Dynamic scaffolds for adhesion and signaling in platelets
    • S.J. Shattil, and P.J. Newman Integrins: dynamic scaffolds for adhesion and signaling in platelets Blood 104 2004 1606 1615
    • (2004) Blood , vol.104 , pp. 1606-1615
    • Shattil, S.J.1    Newman, P.J.2
  • 19
    • 34848900430 scopus 로고    scopus 로고
    • Inhibitory mechanisms of resveratrol in platelet activation: Pivotal roles of p38 MAPK and NO/cyclic GMP
    • M.Y. Shen, G. Hsiao, C.L. Liu, T.H. Fong, K.H. Lin, D.S. Chou, and J.R. Sheu Inhibitory mechanisms of resveratrol in platelet activation: pivotal roles of p38 MAPK and NO/cyclic GMP Br. J. Haematol. 139 2007 475 485
    • (2007) Br. J. Haematol. , vol.139 , pp. 475-485
    • Shen, M.Y.1    Hsiao, G.2    Liu, C.L.3    Fong, T.H.4    Lin, K.H.5    Chou, D.S.6    Sheu, J.R.7
  • 22
    • 1542317617 scopus 로고    scopus 로고
    • Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
    • D. Woulfe, H. Jiang, A. Morgans, R. Monks, M. Birnbaum, and L.F. Brass Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2 J. Clin. Investig. 113 2004 441 450
    • (2004) J. Clin. Investig. , vol.113 , pp. 441-450
    • Woulfe, D.1    Jiang, H.2    Morgans, A.3    Monks, R.4    Birnbaum, M.5    Brass, L.F.6
  • 23
    • 84871746740 scopus 로고    scopus 로고
    • Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugs
    • B. Wright, J.P.E. Spencer, J.A. Lovegrove, and J.M. Gibbins Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugs Cardiovasc. Res. 97 2013 13 22
    • (2013) Cardiovasc. Res. , vol.97 , pp. 13-22
    • Wright, B.1    Spencer, J.P.E.2    Lovegrove, J.A.3    Gibbins, J.M.4
  • 24
    • 84892363888 scopus 로고    scopus 로고
    • 2,3,5,4′-tetrahydroxystilbene-2-O-β-d-glucoside (THSG) attenuates human platelet aggregation, secretion and spreading in vitro
    • K. Xiang, G. Liu, Y.J. Zhou, H.Z. Hao, Z. Yin, A.D. He, X.W. Da, J.Z. Xiang, J.L. Wang, and Z.Y. Ming 2,3,5,4′-tetrahydroxystilbene-2-O-β-d-glucoside (THSG) attenuates human platelet aggregation, secretion and spreading in vitro Thromb. Res. 133 2014 211 217
    • (2014) Thromb. Res. , vol.133 , pp. 211-217
    • Xiang, K.1    Liu, G.2    Zhou, Y.J.3    Hao, H.Z.4    Yin, Z.5    He, A.D.6    Da, X.W.7    Xiang, J.Z.8    Wang, J.L.9    Ming, Z.Y.10
  • 25
    • 79955678071 scopus 로고    scopus 로고
    • Dragons Blood extract has antithrombotic properties, affecting platelet aggregation functions and anticoagulation activities
    • N. Xin, Y.J. Li, Y. Li, R.J. Dai, W.W. Meng, Y. Chen, M. Schlappi, and Y.L. Deng Dragons Blood extract has antithrombotic properties, affecting platelet aggregation functions and anticoagulation activities J. Ethnopharmacol. 135 2011 510 514
    • (2011) J. Ethnopharmacol. , vol.135 , pp. 510-514
    • Xin, N.1    Li, Y.J.2    Li, Y.3    Dai, R.J.4    Meng, W.W.5    Chen, Y.6    Schlappi, M.7    Deng, Y.L.8
  • 26
    • 78751525495 scopus 로고    scopus 로고
    • Inhibitory effects of resveratrol on platelet activation induced by thromboxane a(2) receptor agonist in human platelets
    • Y. Yang, X. Wang, L. Zhang, H. An, and Z. Zao Inhibitory effects of resveratrol on platelet activation induced by thromboxane a(2) receptor agonist in human platelets Am. J. Chin. Med. 39 2011 145 159
    • (2011) Am. J. Chin. Med. , vol.39 , pp. 145-159
    • Yang, Y.1    Wang, X.2    Zhang, L.3    An, H.4    Zao, Z.5
  • 28
    • 84883830422 scopus 로고    scopus 로고
    • Neferine exerts its antithrombotic effect by inhibiting platelet aggregation and promoting dissociation of platelet aggregates
    • Y.-J. Zhou, J.-Z. Xiang, H. Yuan, H. Liu, Q. Tang, H.-Z. Hao, Z. Yin, J. Wang, and Z.-Y. Ming Neferine exerts its antithrombotic effect by inhibiting platelet aggregation and promoting dissociation of platelet aggregates Thromb. Res. 132 2013 202 210
    • (2013) Thromb. Res. , vol.132 , pp. 202-210
    • Zhou, Y.-J.1    Xiang, J.-Z.2    Yuan, H.3    Liu, H.4    Tang, Q.5    Hao, H.-Z.6    Yin, Z.7    Wang, J.8    Ming, Z.-Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.