Dimer-dependent intrinsic/basal activity of the class b g protein-coupled receptor pac1 promotes cellular anti-apoptotic activity through wnt/b-catenin pathways that are associated with dimer endocytosis

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Yu, Rongjie ^a   Cui, Zekai ^a   Li, Mei ^a   Yang, Yanxu ^a  

^a JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 2 [4 (TRIFLUOROMETHYL)PHENYL] 5H THIOPYRANO[4,3 D]PYRIMIDIN 4 OL; ACETYLCYSTEINE; BETA CATENIN; CASPASE 3; CYCLIN D1; DIMER; DOXYCYCLINE; DUAL SPECIFICITY PHOSPHATASE 2; G PROTEIN COUPLED RECEPTOR; LIGAND; MUTANT PROTEIN; MYC PROTEIN; PROTEIN BCL 2; TETRACYCLINE; WNT PROTEIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ASSAY; CHO CELL LINE; CONTROLLED STUDY; DIMERIZATION; DOWN REGULATION; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME REGULATION; GENE EXPRESSION; MOUSE; NEURO2A CELL LINE; NEUROBLASTOMA CELL LINE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SERUM; SIGNAL TRANSDUCTION; ANIMAL; CRICETULUS; GENETICS; HAMSTER; METABOLISM; MUTATION; PROTEIN MULTIMERIZATION; WNT SIGNALING PATHWAY;

CITRUS MAXIMA; CRICETULUS GRISEUS;

ANIMALS; APOPTOSIS; BETA CATENIN; CHO CELLS; CRICETINAE; CRICETULUS; ENDOCYTOSIS; MICE; MUTATION; PROTEIN MULTIMERIZATION; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84913568938     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113913     Document Type: Article

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