메뉴 건너뛰기




Volumn 9, Issue 11, 2014, Pages

Overexpression of Mcl-1L splice variant is associated with poor and prognosis chemoresistance in oral cancers

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; MESSENGER RNA; OBATOCLAX; PROTEIN MCL 1; ANTINEOPLASTIC AGENT; ISOPROTEIN; MCL1 PROTEIN, HUMAN; PYRROLE DERIVATIVE;

EID: 84913554608     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111927     Document Type: Article
Times cited : (43)

References (46)
  • 2
    • 84867818844 scopus 로고    scopus 로고
    • Challenges of the oral cancer burden in India
    • Coelho KR (2012) Challenges of the oral cancer burden in India. Journal of cancer epidemiology 2012.
    • (2012) Journal of Cancer Epidemiology , pp. 2012
    • Coelho, K.R.1
  • 3
    • 0032877668 scopus 로고    scopus 로고
    • Dysregulation of apoptosis in cancer
    • Reed JC (1999) Dysregulation of apoptosis in cancer. Journal of Clinical Oncology 17: 2941-2941.
    • (1999) Journal of Clinical Oncology , vol.17 , pp. 2941-2941
    • Reed, J.C.1
  • 4
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-ordeath switch
    • Cory S, Adams JM (2002) The Bcl2 family: regulators of the cellular life-ordeath switch. Nature Reviews Cancer 2: 647-656.
    • (2002) Nature Reviews Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 5
    • 0036234124 scopus 로고    scopus 로고
    • MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis. Leukemia: Official journal of the Leukemia Society of America
    • Craig R (2002) MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis. Leukemia: official journal of the Leukemia Society of America, Leukemia Research Fund, UK 16: 444.
    • (2002) Leukemia Research Fund, Uk , vol.16 , pp. 444
    • Craig, R.1
  • 6
    • 77954175674 scopus 로고    scopus 로고
    • Mcl-1; the molecular regulation of protein function
    • Thomas LW, Lam C, Edwards SW (2010) Mcl-1; the molecular regulation of protein function. FEBS letters 584: 2981-2989.
    • (2010) FEBS Letters , vol.584 , pp. 2981-2989
    • Thomas, L.W.1    Lam, C.2    Edwards, S.W.3
  • 7
    • 22244464818 scopus 로고    scopus 로고
    • Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
    • Willis SN, Chen L, Dewson G, Wei A, Naik E, et al. (2005) Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes & development 19: 1294-1305.
    • (2005) Genes & Development , vol.19 , pp. 1294-1305
    • Willis, S.N.1    Chen, L.2    Dewson, G.3    Wei, A.4    Naik, E.5
  • 8
    • 67349136004 scopus 로고    scopus 로고
    • Mcl-1 is a potential therapeutic target in multiple types of cancer
    • Akgul C (2009) Mcl-1 is a potential therapeutic target in multiple types of cancer. Cellular and molecular life sciences 66: 1326-1336.
    • (2009) Cellular and Molecular Life Sciences , vol.66 , pp. 1326-1336
    • Akgul, C.1
  • 11
    • 70349246434 scopus 로고    scopus 로고
    • Prognostic role of myeloid cell leukemia-1 protein (Mcl-1) expression in human gastric cancer
    • Likui W, Qun L, Wanqing Z, Haifeng S, Fangqiu L, et al. (2009) Prognostic role of myeloid cell leukemia-1 protein (Mcl-1) expression in human gastric cancer. Journal of surgical oncology 100: 396-400.
    • (2009) Journal of Surgical Oncology , vol.100 , pp. 396-400
    • Likui, W.1    Qun, L.2    Wanqing, Z.3    Haifeng, S.4    Fangqiu, L.5
  • 12
    • 84872822854 scopus 로고    scopus 로고
    • The expression of Mcl- 1 in human cervical cancer and its clinical significance
    • Zhang T, Zhao C, Luo L, Zhao H, Cheng J, et al. (2012) The expression of Mcl- 1 in human cervical cancer and its clinical significance. Medical Oncology 29: 1985-1991.
    • (2012) Medical Oncology , vol.29 , pp. 1985-1991
    • Zhang, T.1    Zhao, C.2    Luo, L.3    Zhao, H.4    Cheng, J.5
  • 13
    • 0036313642 scopus 로고    scopus 로고
    • Increased MCL-1 Expression Is Associated with Poor Prognosis in Ovarian Carcinomas
    • Shigemasa K, Katoh O, Shiroyama Y, Mihara S, Mukai K, et al. (2002) Increased MCL-1 Expression Is Associated with Poor Prognosis in Ovarian Carcinomas. Cancer Science 93: 542-550.
    • (2002) Cancer Science , vol.93 , pp. 542-550
    • Shigemasa, K.1    Katoh, O.2    Shiroyama, Y.3    Mihara, S.4    Mukai, K.5
  • 14
    • 60549100502 scopus 로고    scopus 로고
    • Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1
    • Mallick S, Patil R, Gyanchandani R, Pawar S, Palve V, et al. (2009) Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1. The Journal of pathology 217: 398-407.
    • (2009) The Journal of Pathology , vol.217 , pp. 398-407
    • Mallick, S.1    Patil, R.2    Gyanchandani, R.3    Pawar, S.4    Palve, V.5
  • 15
    • 77956394297 scopus 로고    scopus 로고
    • PCNA and antiapoptotic Mcl-1 proteins predict disease-free survival in oral cancer patients treated with definitive radiotherapy
    • Mallick S, Agarwal J, Kannan S, Pawar S, Kane S, et al. (2010) PCNA and antiapoptotic Mcl-1 proteins predict disease-free survival in oral cancer patients treated with definitive radiotherapy. Oral oncology 46: 688-693.
    • (2010) Oral Oncology , vol.46 , pp. 688-693
    • Mallick, S.1    Agarwal, J.2    Kannan, S.3    Pawar, S.4    Kane, S.5
  • 16
    • 69249226222 scopus 로고    scopus 로고
    • MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death
    • Kim J-H, Sim S-H, Ha H-J, Ko J-J, Lee K, et al. (2009) MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death. FEBS letters 583: 2758-2764.
    • (2009) FEBS Letters , vol.583 , pp. 2758-2764
    • Kim, J.-H.1    Sim, S.-H.2    Ha, H.-J.3    Ko, J.-J.4    Lee, K.5
  • 17
    • 84864550534 scopus 로고    scopus 로고
    • Association of anti-apoptotic Mcl-1L isoform expression with radioresistance of oral squamous carcinoma cells
    • Palve VC, Teni TR (2012) Association of anti-apoptotic Mcl-1L isoform expression with radioresistance of oral squamous carcinoma cells. Radiation Oncology 7: 1-11.
    • (2012) Radiation Oncology , vol.7 , pp. 1-11
    • Palve, V.C.1    Teni, T.R.2
  • 18
    • 34447635894 scopus 로고    scopus 로고
    • Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells
    • Yang C, Kaushal V, Shah SV, Kaushal GP (2007) Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells. American Journal of Physiology-Renal Physiology 292: F1710-F1717.
    • (2007) American Journal of Physiology-Renal Physiology , vol.292 , pp. F1710-F1717
    • Yang, C.1    Kaushal, V.2    Shah, S.V.3    Kaushal, G.P.4
  • 19
    • 70949089720 scopus 로고    scopus 로고
    • Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells
    • Simonin K, Brotin E, Dufort S, Dutoit S, Goux D, et al. (2009) Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells. Molecular cancer therapeutics 8: 3162-3170.
    • (2009) Molecular Cancer Therapeutics , vol.8 , pp. 3162-3170
    • Simonin, K.1    Brotin, E.2    Dufort, S.3    Dutoit, S.4    Goux, D.5
  • 20
    • 79955468507 scopus 로고    scopus 로고
    • Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines
    • Zhang H, Guttikonda S, Roberts L, Uziel T, Semizarov D, et al. (2010) Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines. Oncogene 30: 1963-1968.
    • (2010) Oncogene , vol.30 , pp. 1963-1968
    • Zhang, H.1    Guttikonda, S.2    Roberts, L.3    Uziel, T.4    Semizarov, D.5
  • 23
    • 79955447372 scopus 로고    scopus 로고
    • Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance
    • Park HR, Kim SH, Lee SY, Sung JM, Park AR, et al. (2011) Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance. Cancer 117: 1864-1873.
    • (2011) Cancer , vol.117 , pp. 1864-1873
    • Park, H.R.1    Kim, S.H.2    Lee, S.Y.3    Sung, J.M.4    Park, A.R.5
  • 24
    • 0019471387 scopus 로고
    • Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas
    • Rheinwald JG, Beckett MA (1981) Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas. Cancer research 41: 1657-1663.
    • (1981) Cancer Research , vol.41 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 25
    • 40749138126 scopus 로고    scopus 로고
    • Chromosomal imbalances in oral squamous cell carcinoma: Examination of 31 cell lines and review of the literature
    • Martin CL, Reshmi SC, Ried T, Gottberg W, Wilson JW, et al. (2008) Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature. Oral oncology 44: 369-382.
    • (2008) Oral Oncology , vol.44 , pp. 369-382
    • Martin, C.L.1    Reshmi, S.C.2    Ried, T.3    Gottberg, W.4    Wilson, J.W.5
  • 27
    • 4043082812 scopus 로고    scopus 로고
    • Implications of cytokeratin 8/18 filament formation in stratified epithelial cells: Induction of transformed phenotype
    • Raul U, Sawant S, Dange P, Kalraiya R, Ingle A, et al. (2004) Implications of cytokeratin 8/18 filament formation in stratified epithelial cells: induction of transformed phenotype. Int J Cancer 111: 662-668.
    • (2004) Int J Cancer , vol.111 , pp. 662-668
    • Raul, U.1    Sawant, S.2    Dange, P.3    Kalraiya, R.4    Ingle, A.5
  • 28
    • 0026683812 scopus 로고
    • DOK, a cell line established from human dysplastic oral mucosa, shows a partially transformed nonmalignant phenotype
    • Chang SE, Foster S, Betts D, Marnock WE (1992) DOK, a cell line established from human dysplastic oral mucosa, shows a partially transformed nonmalignant phenotype. International journal of cancer 52: 896-902.
    • (1992) International Journal Of Cancer , vol.52 , pp. 896-902
    • Chang, S.E.1    Foster, S.2    Betts, D.3    Marnock, W.E.4
  • 29
    • 40749138126 scopus 로고    scopus 로고
    • Chromosomal imbalances in oral squamous cell carcinoma. Examination of 31 cell lines and review of the literature
    • Martin CL, Reshmi SC, Ried T, Gottberg W, Wilson JW, et al. (2008) Chromosomal imbalances in oral squamous cell carcinoma. Examination of 31 cell lines and review of the literature. Oral oncology 44: 369.
    • (2008) Oral Oncology , vol.44 , pp. 369
    • Martin, C.L.1    Reshmi, S.C.2    Ried, T.3    Gottberg, W.4    Wilson, J.W.5
  • 30
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative CT method
    • Schmittgen TD, Livak KJ (2008) Analyzing real-time PCR data by the comparative CT method. Nature protocols 3: 1101-1108.
    • (2008) Nature Protocols , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 31
    • 65449131246 scopus 로고    scopus 로고
    • Expression of Mcl-1 splicing variants in clear-cell renal cancer and their correlation with histopathological parameters and prognosis
    • Kempkensteffen C, Hinz S, Johannsen M, Krause H, Magheli A, et al. (2009) Expression of Mcl-1 splicing variants in clear-cell renal cancer and their correlation with histopathological parameters and prognosis. Tumor Biology 30: 73-79.
    • (2009) Tumor Biology , vol.30 , pp. 73-79
    • Kempkensteffen, C.1    Hinz, S.2    Johannsen, M.3    Krause, H.4    Magheli, A.5
  • 32
    • 84872675104 scopus 로고    scopus 로고
    • MiR-101 and Mcl-1 in non-small- cell lung cancer: Expression profile and clinical significance
    • Luo L, Zhang T, Liu H, Lv T, Yuan D, et al. (2012) MiR-101 and Mcl-1 in non-small- cell lung cancer: expression profile and clinical significance. Medical Oncology 29: 1681-1686.
    • (2012) Medical Oncology , vol.29 , pp. 1681-1686
    • Luo, L.1    Zhang, T.2    Liu, H.3    Lv, T.4    Yuan, D.5
  • 33
    • 0034682837 scopus 로고    scopus 로고
    • MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain
    • Bae J, Leo CP, Hsu SY, Hsueh AJ (2000) MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain. J Biol Chem 275: 25255-25261.
    • (2000) J Biol Chem , vol.275 , pp. 25255-25261
    • Bae, J.1    Leo, C.P.2    Hsu, S.Y.3    Hsueh, A.J.4
  • 34
    • 84872822854 scopus 로고    scopus 로고
    • The expression of Mcl- 1 in human cervical cancer and its clinical significance
    • Zhang T, Zhao C, Luo L, Zhao H, Cheng J, et al. (2012) The expression of Mcl- 1 in human cervical cancer and its clinical significance. Medical Oncology: 1-7.
    • (2012) Medical Oncology , pp. 1-7
    • Zhang, T.1    Zhao, C.2    Luo, L.3    Zhao, H.4    Cheng, J.5
  • 35
    • 55749105701 scopus 로고    scopus 로고
    • Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers
    • Pepper C, Lin TT, Pratt G, Hewamana S, Brennan P, et al. (2008) Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 112: 3807-3817.
    • (2008) Blood , vol.112 , pp. 3807-3817
    • Pepper, C.1    Lin, T.T.2    Pratt, G.3    Hewamana, S.4    Brennan, P.5
  • 36
    • 85046914188 scopus 로고    scopus 로고
    • Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists
    • Lestini BJ, Goldsmith KC, Fluchel MN, Liu X, Chen NL, et al. (2009) Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists. Cancer biology & therapy 8: 1587-1595.
    • (2009) Cancer Biology [[Ampi]]amp; Therapy , vol.8 , pp. 1587-1595
    • Lestini, B.J.1    Goldsmith, K.C.2    Fluchel, M.N.3    Liu, X.4    Chen, N.L.5
  • 37
    • 40749122965 scopus 로고    scopus 로고
    • Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis
    • Chetoui N, Sylla K, Gagnon-Houde J-V, Alcaide-Loridan C, Charron D, et al. (2008) Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis. Molecular Cancer Research 6: 42-52.
    • (2008) Molecular Cancer Research , vol.6 , pp. 42-52
    • Chetoui, N.1    Sylla, K.2    Gagnon-Houde, J.-V.3    Alcaide-Loridan, C.4    Charron, D.5
  • 38
    • 33750051632 scopus 로고    scopus 로고
    • Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction
    • Schulze-Bergkamen H, Fleischer B, Schuchmann M, Weber A, Weinmann A, et al. (2006) Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction. BMC cancer 6: 232.
    • (2006) BMC Cancer , vol.6 , pp. 232
    • Schulze-Bergkamen, H.1    Fleischer, B.2    Schuchmann, M.3    Weber, A.4    Weinmann, A.5
  • 39
    • 28844437366 scopus 로고    scopus 로고
    • Mcl-1 overexpression in hepatocellular carcinoma: A potential target for antisense therapy
    • Sieghart W, Losert D, Strommer S, Cejka D, Schmid K, et al. (2006) Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy. Journal of hepatology 44: 151-157.
    • (2006) Journal of Hepatology , vol.44 , pp. 151-157
    • Sieghart, W.1    Losert, D.2    Strommer, S.3    Cejka, D.4    Schmid, K.5
  • 41
    • 79960805359 scopus 로고    scopus 로고
    • Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma
    • Tsai LL, Yu CC, Chang YC, Yu CH, Chou MY (2011) Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 40: 621-628.
    • (2011) Journal of Oral Pathology & Medicine , vol.40 , pp. 621-628
    • Tsai, L.L.1    Yu, C.C.2    Chang, Y.C.3    Yu, C.H.4    Chou, M.Y.5
  • 42
    • 84913569492 scopus 로고    scopus 로고
    • Expression of MUC4 is correlated with chemoresistance and survival in oral squamous cell carcinoma
    • Aaoms
    • Hamada T (2014) Expression of MUC4 is correlated with chemoresistance and survival in oral squamous cell carcinoma. 2014 Annual Meeting. Aaoms.
    • (2014) 2014 Annual Meeting
    • Hamada, T.1
  • 43
    • 84904869185 scopus 로고    scopus 로고
    • Secretory Kin17 is Correlated with Chemoresistance in Oral Squamous Cell Carcinoma
    • Liu X, Deng L, Zhang H, Zeng T, Wang H, et al. (2014) Secretory Kin17 is Correlated with Chemoresistance in Oral Squamous Cell Carcinoma. Journal of Analytical Oncology 3: 18-25.
    • (2014) Journal of Analytical Oncology , vol.3 , pp. 18-25
    • Liu, X.1    Deng, L.2    Zhang, H.3    Zeng, T.4    Wang, H.5
  • 44
    • 33846674886 scopus 로고    scopus 로고
    • Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation
    • Chen S, Dai Y, Harada H, Dent P, Grant S (2007) Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation. Cancer research 67: 782-791.
    • (2007) Cancer Research , vol.67 , pp. 782-791
    • Chen, S.1    Dai, Y.2    Harada, H.3    Dent, P.4    Grant, S.5
  • 45
    • 84897019340 scopus 로고    scopus 로고
    • The pan-Bcl-2 blocker obatoclax promotes the expression of Puma, Noxa, and Bim mRNA and induces apoptosis in neoplastic mast cells
    • Peter B, Cerny-Reiterer S, Hadzijusufovic E, Schuch K, Stefanzl G, et al. (2013) The pan-Bcl-2 blocker obatoclax promotes the expression of Puma, Noxa, and Bim mRNA and induces apoptosis in neoplastic mast cells. Journal of leukocyte biology.
    • (2013) Journal of Leukocyte Biology
    • Peter, B.1    Cerny-Reiterer, S.2    Hadzijusufovic, E.3    Schuch, K.4    Stefanzl, G.5
  • 46
    • 84891826874 scopus 로고    scopus 로고
    • Single-agent obatoclax (GX15-070) potently induces apoptosis and pro-survival autophagy in head and neck squamous cell carcinoma cells
    • Yazbeck VY, Li C, Grandis JR, Zang Y, Johnson DE (2014) Single-agent obatoclax (GX15-070) potently induces apoptosis and pro-survival autophagy in head and neck squamous cell carcinoma cells. Oral oncology 50: 120-127.
    • (2014) Oral Oncology , vol.50 , pp. 120-127
    • Yazbeck, V.Y.1    Li, C.2    Grandis, J.R.3    Zang, Y.4    Johnson, D.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.