Specific contributions of N-methyl-D-aspartate receptors in the dorsal striatum to cognitive flexibility

Neuroscience

Volumn 284, Issue , 2015, Pages 934-942

  Darvas, M ^a   Palmiter, R D ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Direct pathway; Executive function; Knockout; Learning; Medium spiny neuron; Plasticity

Indexed keywords

ADENOASSOCIATED VIRUS 1 CRE RECOMBINASE GREEN FLUORESCENT PROTEIN; DYNORPHIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG; ENKEPHALIN; GPRIN1 PROTEIN, MOUSE; NERVE PROTEIN; PREPROENKEPHALIN; PROTEIN PRECURSOR;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE FLEXIBILITY; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; GENE; GENE INACTIVATION; GRIN1 GENE; LEARNING; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SUBUNIT; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; EXECUTIVE FUNCTION; EXPLORATORY BEHAVIOR; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; MAZE TEST; METABOLISM; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; TRANSGENIC MOUSE;

ANIMALS; COGNITION; CORPUS STRIATUM; DYNORPHINS; ENKEPHALINS; EXECUTIVE FUNCTION; EXPLORATORY BEHAVIOR; HEK293 CELLS; HUMANS; MAZE LEARNING; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; PROTEIN PRECURSORS; PSYCHOMOTOR PERFORMANCE; RECEPTORS, N-METHYL-D-ASPARTATE; REVERSAL LEARNING;

EID: 84913554063     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.11.011     Document Type: Article

References (47)

1. Abercrombie E.D., Bonatz A.E., Zigmond M.J. Effects of l-dopa on extracellular dopamine in striatum of normal and 6-hydroxydopamine-treated rats. Brain Res 1990, 525:36-44.
2. Albin R.L., Makowiec R.L., Hollingsworth Z.R., Dure LSt, Penney JB, Young AB Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic study. Neuroscience 1992, 46:35-48.
3. Alexander G.E., DeLong M.R., Strick P.L. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 1986, 9:357-381.
4. Beutler L.R., Eldred K.C., Quintana A., Keene C.D., Rose S.E., Postupna N., Montine T.J., Palmiter R.D. Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons. PLoS One 2011, 6:e28168.
5. Boulougouris V., Castane A., Robbins T.W. Dopamine D2/D3 receptor agonist quinpirole impairs spatial reversal learning in rats: investigation of D3 receptor involvement in persistent behavior. Psychopharmacology (Berl) 2009, 202:611-620.
6. Braun S., Hauber W. The dorsomedial striatum mediates flexible choice behavior in spatial tasks. Behav Brain Res 2011, 220:288-293.
7. Buckner R.L. Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate. Neuron 2004, 44:195-208.
8. Clarke H.F., Walker S.C., Crofts H.S., Dalley J.W., Robbins T.W., Roberts A.C. Prefrontal serotonin depletion affects reversal learning but not attentional set shifting. J Neurosci 2005, 25:532-538.
9. Dang M.T., Yokoi F., Yin H.H., Lovinger D.M., Wang Y., Li Y. Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum. Proc Natl Acad Sci USA 2006, 103:15254-15259.
10. Darvas M., Henschen C.W., Palmiter R.D. Contributions of signaling by dopamine neurons in dorsal striatum to cognitive behaviors corresponding to those observed in Parkinson's disease. Neurobiol Dis 2014, 65:112-123.
11. Darvas M., Palmiter R.D. Restriction of dopamine signaling to the dorsolateral striatum is sufficient for many cognitive behaviors. Proc Natl Acad Sci USA 2009, 106:14664-14669.
12. Darvas M., Palmiter R.D. Restricting dopaminergic signaling to either dorsolateral or medial striatum facilitates cognition. J Neurosci 2010, 30:1158-1165.
13. Darvas M., Palmiter R.D. Contributions of striatal dopamine signaling to the modulation of cognitive flexibility. Biol Psychiatry 2011, 69:704-707.
14. De Steno D.A., Schmauss C. A role for dopamine D2 receptors in reversal learning. Neuroscience 2009, 162:118-127.
15. Dorsey E.R., Beck C.A., Darwin K., Nichols P., Brocht A.F., Biglan K.M., Shoulson I. Natural history of Huntington disease. JAMA Neurol 2013, 70:1520-1530. Huntington Study Group CI.
16. Dunnett S.B., Iversen S.D. Sensorimotor impairments following localized kainic acid and 6-hydroxydopamine lesions of the neostriatum. Brain Res 1982, 248:121-127.
17. Floresco S.B., Ghods-Sharifi S., Vexelman C., Magyar O. Dissociable roles for the nucleus accumbens core and shell in regulating set shifting. J Neurosci 2006, 26:2449-2457.
18. Floresco S.B., Magyar O. Mesocortical dopamine modulation of executive functions: beyond working memory. Psychopharmacology (Berl) 2006, 188:567-585.
19. Forrest D., Yuzaki M., Soares H.D., Ng L., Luk D.C., Sheng M., Stewart C.L., Morgan J.I., Connor J.A., Curran T. Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron 1994, 13:325-338.
20. Fricker R.A., Annett L.E., Torres E.M., Dunnett S.B. The placement of a striatal ibotenic acid lesion affects skilled forelimb use and the direction of drug-induced rotation. Brain Res Bull 1996, 41:409-416.
21. Gerfen C.R. The neostriatal mosaic: multiple levels of compartmental organization in the basal ganglia. Annu Rev Neurosci 1992, 15:285-320.
22. Groman S.M., Lee B., London E.D., Mandelkern M.A., James A.S., Feiler K., Rivera R., Dahlbom M., Sossi V., Vandervoort E., Jentsch J.D. Dorsal striatal D2-like receptor availability covaries with sensitivity to positive reinforcement during discrimination learning. J Neurosci 2011, 31:7291-7299.
23. Howard C.D., Keefe K.A., Garris P.A., Daberkow D.P. Methamphetamine neurotoxicity decreases phasic, but not tonic, dopaminergic signaling in the rat striatum. J Neurochem 2011, 118:668-676.
24. Kellendonk C., Simpson E.H., Polan H.J., Malleret G., Vronskaya S., Winiger V., Moore H., Kandel E.R. Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning. Neuron 2006, 49:603-615.
25. Kelley A.E. Memory and addiction: shared neural circuitry and molecular mechanisms. Neuron 2004, 44:161-179.
26. Lawrence A.D., Sahakian B.J., Rogers R.D., Hodge J.R., Robbins T.W. Discrimination, reversal, and shift learning in Huntington's disease: mechanisms of impaired response selection. Neuropsychologia 1999, 37:1359-1374.
27. Lee B., Groman S., London E.D., Jentsch J.D. Dopamine D2/D3 receptors play a specific role in the reversal of a learned visual discrimination in monkeys. Neuropsychopharmacology 2007, 32:2125-2134.
28. Leverenz J.B., Quinn J.F., Zabetian C., Zhang J., Montine K.S., Montine T.J. Cognitive impairment and dementia in patients with Parkinson disease. Curr Top Med Chem 2009, 9:903-912.
29. Lima C.F., Meireles L.P., Fonseca R., Castro S.L., Garrett C. The Frontal Assessment Battery (FAB) in Parkinson's disease and correlations with formal measures of executive functioning. J Neurol 2008, 255:1756-1761.
30. Madisen L., Zwingman T.A., Sunkin S.M., Oh S.W., Zariwala H.A., Gu H., Ng L.L., Palmiter R.D., Hawrylycz M.J., Jones A.R., Lein E.S., Zeng H. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci 2010, 13:133-140.
31. Palencia C.A., Ragozzino M.E. The influence of NMDA receptors in the dorsomedial striatum on response reversal learning. Neurobiol Learn Mem 2004, 82:81-89.
32. Parker J.G., Beutler L.R., Palmiter R.D. The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning. J Neurosci 2011, 31:11362-11369.
33. Pisa M., Cyr J. Regionally selective roles of the rat's striatum in modality-specific discrimination learning and forelimb reaching. Behav Brain Res 1990, 37:281-292.
34. Quintana A., Zanella S., Koch H., Kruse S.E., Lee D., Ramirez J.M., Palmiter R.D. Fatal breathing dysfunction in a mouse model of Leigh syndrome. J Clin Invest 2012, 122:2359-2368.
35. Rabinowitz J.E., Rolling F., Li C., Conrath H., Xiao W., Xiao X., Samulski R.J. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. J Virol 2002, 76:791-801.
36. Ragozzino M.E., Mohler E.G., Prior M., Palencia C.A., Rozman S. Acetylcholine activity in selective striatal regions supports behavioral flexibility. Neurobiol Learn Mem 2009, 91:13-22.
37. Ragozzino M.E., Ragozzino K.E., Mizumori S.J., Kesner R.P. Role of the dorsomedial striatum in behavioral flexibility for response and visual cue discrimination learning. Behav Neurosci 2002, 116:105-115.
38. Richfield E.K., Penney J.B., Young A.B. Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system. Neuroscience 1989, 30:767-777.
39. Robbins T.W. Chemistry of the mind: neurochemical modulation of prefrontal cortical function. J Comp Neurol 2005, 493:140-146.
40. Robinson T.E., Mocsary Z., Camp D.M., Whishaw I.Q. Time course of recovery of extracellular dopamine following partial damage to the nigrostriatal dopamine system. J Neurosci 1994, 14:2687-2696.
41. Samii A., Nutt J.G., Ransom B.R. Parkinson's disease. Lancet 2004, 363:1783-1793.
42. Shaner N.C., Steinbach P.A., Tsien R.Y. A guide to choosing fluorescent proteins. Nat Methods 2005, 2:905-909.
43. Simpson E.H., Kellendonk C., Kandel E. A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia. Neuron 2010, 65:585-596.
44. Tsien J.Z., Huerta P.T., Tonegawa S. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 1996, 87:1327-1338.
45. Voorn P., Vanderschuren L.J., Groenewegen H.J., Robbins T.W., Pennartz C.M. Putting a spin on the dorsal-ventral divide of the striatum. Trends Neurosci 2004, 27:468-474.
46. Wall V.Z., Parker J.G., Fadok J.P., Darvas M., Zweifel L., Palmiter R.D. A behavioral genetics approach to understanding D1 receptor involvement in phasic dopamine signaling. Mol Cell Neurosci 2011, 46:21-31.
47. Wang W., Darvas M., Storey G.P., Bamford I.J., Gibbs J.T., Palmiter R.D., Bamford N.S. Acetylcholine encodes long-lasting presynaptic plasticity at glutamatergic synapses in the dorsal striatum after repeated amphetamine exposure. J Neurosci 2013, 33:10405-10426.