Transcriptome analysis on the inflammatory cell infiltration of nonalcoholic steatohepatitis in Bama minipigs induced by a long-term high-fat, high-sucrose diet

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Xia, Jihan ^a   Yuan, Jing ^a,b   Xin, Leilei ^a   Zhang, Yuanyuan ^c   Kong, Siyuan ^a   Chen, Yaoxing ^c   Yang, Shulin ^a   Li, Kui ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b Clinical Medical College of Yangtze University   (China)

^c CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; CYTOKINE RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C JUN; PROTEIN FOS; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TRANSCRIPTOME; CARBOHYDRATE DIET; FAT INTAKE; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; DATA ANALYSIS; EOSINOPHIL; FEMALE; HIGH THROUGHPUT SEQUENCING; INFLAMMATION; INFLAMMATORY CELL; KUPFFER CELL; LIPID DIET; LIVER; LYMPHOCYTE; MALE; METABOLIC SYNDROME X; MINIPIG; NATURAL KILLER CELL; NEUTROPHIL; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; RNA SEQUENCE; SIGNAL TRANSDUCTION; SUGAR INTAKE; T LYMPHOCYTE; ADVERSE EFFECTS; ANIMAL; CARBOHYDRATE DIET; CHEMICALLY INDUCED; DRUG EFFECTS; FAT INTAKE; GENETICS; HUMAN; METABOLISM; NUCLEIC ACID DATABASE; PATHOLOGY; PHARMACOLOGY; PIG;

ANIMALS; CYTOKINES; DATABASES, NUCLEIC ACID; DIETARY CARBOHYDRATES; DIETARY FATS; FEMALE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INFLAMMATION; KUPFFER CELLS; MALE; MAP KINASE SIGNALING SYSTEM; NON-ALCOHOLIC FATTY LIVER DISEASE; SUCROSE; SWINE; SWINE, MINIATURE; TRANSCRIPTOME;

EID: 84913550645     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113724     Document Type: Article

References (44)

1. Hotamisligil GS (2006) Inflammation and metabolic disorders. Nature 444: 860-867.
2. Cohen JC, Horton JD, Hobbs HHvb (2011) Human fatty liver disease: old questions and new insights. Science Vol.332(6037): 1519-23.
3. Marchesini G, Brizi M, Morselli-Labate AM, Bianchi G, Bugianesi E, et al. (1999) Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 107: 450-455.
4. Harmon RC, Tiniakos DG, Argo CK (2011) Inflammation in nonalcoholic steatohepatitis. Expert Rev Gastroenterol Hepatol 5: 189-200.
5. Argo CK, Northup PG, Al-Osaimi AM, Caldwell SH (2009) Systematic review of risk factors for fibrosis progression in nonalcoholic steatohepatitis. J. Hepatol 51(2), 371-379.
6. Van Gaal LF, Mertens IL, De Block CE (2006) Mechanisms linking obesity with cardiovascular disease. Nature 444: 875-880.
7. Despres JP, Lemieux I (2006) Abdominal obesity and metabolic syndrome. Nature 444: 881-887.
8. Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444: 840-846.
9. Zhang N, Jing W, Cheng J, Cui W, Mu Y, et al. (2011) Molecular characterization and NF-kappaBregulated transcription of selenoprotein S from the Bama mini-pig. Mol Biol Rep 38: 4281-4286.
10. Spurlock ME, Gabler NK (2008) The development of porcine models of obesity and the metabolic syndrome. J Nutr 138(2): 397-402.
11. Kim KH, Kang YJ, Kim DH, Yoon MY, Moon JK, et al. (2011) RNA-Seq analysis of a soybean nearisogenic line carrying bacterial leaf pustule-resistant and-susceptible alleles. DNA Res 18: 483-497.
12. Fullwood MJ, Wei CL, Liu ET, Ruan Y (2009) Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses. Genome Res 19: 521-532.
13. Chen C, Ai H, Ren J, Li W, Li P, et al. (2011) A global view of porcine transcriptome in three tissues from a full-sib pair with extreme phenotypes in growth and fat deposition by paired-end RNA sequencing. BMC Genomics 12: 448.
14. Wilhelm, B T. and J. R Landry (2009) RNA-Seq-quantitative measurement of expression through massively parallel RNA-sequencing. Methods 48(3): 249-257.
15. Blencowe BJ, Ahmad S, Lee LJ (2009) Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes. Genes & Development 23: 1379-1386.
16. Wang Z, Gerstein M, Snyder M (2009) RNA-Seq: a revolutionary tool for transcriptomics. Nature Reviews Genetics 10: 57-63.
17. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR (1999) Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 94: 2467-2474.
18. Mortazavi A, Williams BA, McCue K, Schaeffer L (2008) Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods 5(7): 621-628.
19. Wang L, Feng Z, Wang X, Wang X, Zhang X (2010) DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Bioinformatics 26: 136-138.
20. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society Series B (Methodological) 57: 289-300.
21. Badisco L, Huybrechts J, Simonet G, Verlinden H, Marchal E, et al. (2011) Transcriptome analysis of the desert locust central nervous system: production and annotation of a Schistocerca gregaria EST database. PLoS ONE 6(3): e17274.
22. Farrell GC, Larter CZ (2006) Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43: S99-S112.
23. Brunt EM (2010) Pathology of nonalcoholic fatty liver disease. Nat Rev Gastroenterol Hepatol 7: 195-203.
24. Valenti L, Fracanzani AL, Fargion S (2009) The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease? Semin Immunopathol 31: 359-369.
25. Baffy G (2009) Kupffer cells in nonalcoholic fatty liver disease: the emerging view. J Hepatol 51: 212-223.
26. Ikura Y, Ohsawa M, Suekane T, Fukushima H, Itabe H, et al. (2006) Localization of oxidized phosphatidylcholine in nonalcoholic fatty liver disease: Impact on disease progression. Hepatology 43: 506-514.
27. Kremer M, Thomas E, Milton RJ, Perry AW, van Rooijen N, et al. (2010) Kupffer Cell and Interleukin-12-Dependent Loss of Natural Killer T Cells in Hepatosteatosis. Hepatology 51: 130-141.
28. Cai DS, Yuan MS, Frantz DF, Melendez PA, Hansen L, et al. (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappa B. Nature Medicine11: 183-190.
29. Daynes RA, Jones DC (2002) Emerging roles of PPARs in inflammation and immunity. Nat Rev Immunol 2: 748-759.
30. Herlaar E, Brown Z (1999) p38 MAPK signalling cascades in inflammatory disease. Mol Med Today 5: 439-447.
31. Charo IF, Ransohoff RM (2006) The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 354: 610-621.
32. Lasagni L, Francalanci M, Annunziato F, Lazzeri E, Giannini S, et al. (2003) An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J Exp Med 197: 1537-1549.
33. Mao X, McElwaine S (2008) Functional copy number changes in Sezary syndrome: toward an integrated molecular cytogenetic map III. Cancer Genet Cytogenet 185: 86-94.
34. Vanhaesebroeck B, Guillermet-Guibert J, Graupera M, Bilanges B (2010) The emerging mechanisms of isoform-specific PI3K signalling. Nat Rev Mol Cell Biol 11: 329-341.
35. Fukui Y, Hashimoto O, Sanui T, Oono T, Koga H, et al. (2001) Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature 412: 826-831.
36. Chang KH, Sanchez-Aguilera A, Shen S, Sengupta A, Madhu MN, et al. (2012) Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival. Blood 120: 800-811.
37. Kiyohara C, Tanaka K, Miyake Y (2008) Genetic susceptibility to atopic dermatitis. Allergol Int 57: 39-56.
38. Tsou RC, Bence KK (2012) The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency. J Obes 2012: 926857.
39. Kremer AN, van der Griendt JC, van der Meijden ED, Honders MW, Ayoglu B, et al. (2014) Development of a coordinated allo T cell and auto B cell response against autosomal PTK2B after allogeneic hematopoietic stem cell transplantation. Haematologica 99: 365-369.
40. Knyazhitsky M, Moas E, Shaginov E, Luria A, Braiman A (2012) Vav1 oncogenic mutation inhibits T cell receptor-induced calcium mobilization through inhibition of phospholipase Cgamma1 activation. J Biol Chem 287: 19725-19735.
41. Haas C, Hanson E, Ballantyne J (2012) Capillary electrophoresis of a multiplex reverse transcriptionpolymerase chain reaction to target messenger RNA markers for body fluid identification. Methods Mol Biol 830: 169-183.
42. Hulme JS, Barratt BJ, Twells RC, Cooper JD, Lowe CE, et al. (2004) Association analysis of the lymphocyte-specific protein tyrosine kinase (LCK) gene in type 1 diabetes. Diabetes 53: 2479-2482.
43. Blobe GC, Obeid LM, Hannun YA (1994) Regulation of protein kinase C and role in cancer biology. Cancer Metastasis Rev 13: 411-431.
44. Chen JH, He HC, Jiang FN, Militar J, Ran PY, et al. (2012) Analysis of the specific pathways and networks of prostate cancer for gene expression profiles in the Chinese population. Med Oncol 29: 1972-1984.