Structures and bioactivities of dihydrochalcones from metrodorea stipularis

Journal of Natural Products

Volumn 77, Issue 11, 2014, Pages 2418-2422

  De Melo Burger, Marcela C ^a   Fernandes, João Batista ^a   Das Graças Fernandes Da Silva, Maria F ^a   Escalante, Aster ^b   Prudhomme, Jacques ^b   Le Roch, Karine G ^b   Izidoro, Mario A ^c   Vieira, Paulo C ^a  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5,7 DIHYDROXY 2,2 DIMETHYLCHROMAN 6 YL) 3 (1,1,4A TRIMETHYL 2,3,4,4A 9A HEXAHYDRO 1H XANTHEN 7 YL)PROPAN 1 ONE; 1 (5,7 DIHYDROXY 2,2 DIMETHYLCHROMAN 6 YL) 3 (2,2 DIMETHYLCHROMAN 6 YL)PROPAN 1 ONE; 1 (5,7 DIHYDROXY 2,2 DIMETHYLCHROMAN 6 YL) 3 [4 HYDROXY 3 (3 METHYLBUT 2 EN 1 YL)]PROPAN 1 ONE; ANTIMALARIAL AGENT; CATHEPSIN B; CATHEPSIN L; CRUZIPAIN; CYSTEINE PROTEINASE INHIBITOR; DIHYDROCHALCONE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PLANT EXTRACT; UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; CHALCONE DERIVATIVE;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SELECTIVITY; EC50; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC50; METRODOREA STIPULARIS; MICROBIAL GROWTH; NONHUMAN; PLASMODIUM FALCIPARUM; RUTACEAE; ANTAGONISTS AND INHIBITORS; BRAZIL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG SENSITIVITY; ISOLATION AND PURIFICATION; PLANT STEM; TRYPANOSOMA CRUZI;

ANTIMALARIALS; ANTIPROTOZOAL AGENTS; BRAZIL; CATHEPSIN B; CATHEPSIN L; CHALCONES; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PLANT STEMS; PLASMODIUM FALCIPARUM; TRYPANOSOMA CRUZI;

EID: 84913528804     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np500453x     Document Type: Article

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