Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 47, 2014, Pages 16949-16954

  Tóth, Balázs ^a   Iordanov, Iordan ^a   Csanády, László ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

ADP ribose analog; Channel enzyme; Ligand gated channel; Nonequilibrium; Nudix motif

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE DIPHOSPHATE RIBOSE PYROPHOSPHATASE; ADENOSINE PHOSPHATE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; LIGAND GATED ION CHANNEL; NUDIX TYPE MOTIF 9; PROTEIN; RIBOSE 5 PHOSPHATE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; UNCLASSIFIED DRUG; LIGAND; TRANSIENT RECEPTOR POTENTIAL CHANNEL M;

ARTICLE; BINDING AFFINITY; CATALYSIS; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME CONFORMATION; HYDROLYSIS; INSULIN RELEASE; LIGAND BINDING; STEADY STATE; ANIMAL; PHYSIOLOGY; XENOPUS LAEVIS;

ANIMALS; HYDROLYSIS; ION CHANNEL GATING; LIGANDS; TRPM CATION CHANNELS; XENOPUS LAEVIS;

EID: 84912567140     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1412449111     Document Type: Article

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