메뉴 건너뛰기




Volumn 19, Issue 11, 2014, Pages 18232-18247

Sulfated chitosan oligosaccharides suppress LPS-induced NO production via JNK and NF-κB inactivation

Author keywords

Anti inflammatory; MAPKs pathways; RAW264.7 cells; Sulfated chitosan oligosaccharides

Indexed keywords

CHITOSAN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; NITRIC OXIDE; NOS2 PROTEIN, MOUSE; OLIGOSACCHARIDE; RELA PROTEIN, MOUSE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84912535702     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules191118232     Document Type: Article
Times cited : (47)

References (39)
  • 2
    • 53949109389 scopus 로고    scopus 로고
    • Antioxidant activity of N-carboxymethyl chitosan oligosaccharides
    • Sun, T.; Yao, Q.; Zhou, D.; Mao, F. Antioxidant activity of N-carboxymethyl chitosan oligosaccharides. Bioorg. Med. Chem. Lett. 2008, 18, 5774-5776.
    • (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 5774-5776
    • Sun, T.1    Yao, Q.2    Zhou, D.3    Mao, F.4
  • 3
    • 34250654485 scopus 로고    scopus 로고
    • Preparation of chitosan oligomers and their antioxidant activity
    • Sun, T.; Zhou, D.X.; Xie, J.L.; Mao, F. Preparation of chitosan oligomers and their antioxidant activity. Eur. Food Res. Technol. 2007, 225, 451-456.
    • (2007) Eur. Food Res. Technol. , vol.225 , pp. 451-456
    • Sun, T.1    Zhou, D.X.2    Xie, J.L.3    Mao, F.4
  • 4
    • 34447535416 scopus 로고    scopus 로고
    • Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage
    • Jung, C.H.; Jung, H.; Shin, Y.C.; Park, J.H.; Jun, C.Y.; Kim, H.M.; Yim, H.S.; Shin, M.G.; Bae, H.S.; Kim, S.H.; et al. Eleutherococcus senticosus extract attenuates LPS-induced iNOS expression through the inhibition of Akt and JNK pathways in murine macrophage. J. Ethnopharmacol. 2007, 113, 183-187.
    • (2007) J. Ethnopharmacol. , vol.113 , pp. 183-187
    • Jung, C.H.1    Jung, H.2    Shin, Y.C.3    Park, J.H.4    Jun, C.Y.5    Kim, H.M.6    Yim, H.S.7    Shin, M.G.8    Bae, H.S.9    Kim, S.H.10
  • 5
    • 22544453352 scopus 로고    scopus 로고
    • Chitooligosaccharides as a novel β-secretase inhibitor
    • Byun, H.G.; Kim, Y.T.; Park, P.J.; Lin, X.; Kim, S.K. Chitooligosaccharides as a novel β-secretase inhibitor. Carbohydr. Polym. 2005, 61, 198-202.
    • (2005) Carbohydr. Polym. , vol.61 , pp. 198-202
    • Byun, H.G.1    Kim, Y.T.2    Park, P.J.3    Lin, X.4    Kim, S.K.5
  • 6
    • 79960559680 scopus 로고    scopus 로고
    • Effect of anticoagulative sulfated polysaccharide purified from enzyme-assistant extract of a brown seaweed Ecklonia cava on Wistar rats
    • Wijesinghe, W.A.J.P.; Athukorala, Y.; Jeon, Y.J. Effect of anticoagulative sulfated polysaccharide purified from enzyme-assistant extract of a brown seaweed Ecklonia cava on Wistar rats. Carbohydr. Polym. 2011, 86, 917-921.
    • (2011) Carbohydr. Polym. , vol.86 , pp. 917-921
    • Wijesinghe, W.A.J.P.1    Athukorala, Y.2    Jeon, Y.J.3
  • 7
    • 0021564388 scopus 로고
    • The cell biology of macrophage activation
    • Adams, D.O.; Hamilton, T.A. The cell biology of macrophage activation. Annu. Rev. Immunol. 1984, 2, 283-318.
    • (1984) Annu. Rev. Immunol. , vol.2 , pp. 283-318
    • Adams, D.O.1    Hamilton, T.A.2
  • 8
    • 0037281863 scopus 로고    scopus 로고
    • The inflammatory macrophage: A story of Jekyll and Hyde
    • Duffield, J.S. The inflammatory macrophage: A story of Jekyll and Hyde. Clin. Sci. 2003, 104, 27-38.
    • (2003) Clin. Sci. , vol.104 , pp. 27-38
    • Duffield, J.S.1
  • 10
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada, S.; Palmer, R.M.; Higgs, D.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 1991, 43, 109-142.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, D.A.3
  • 11
    • 0032948112 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase as a potential therapeutic target
    • Hobbs, A.J.; Higgs, A.; Moncada, S. Inhibition of nitric oxide synthase as a potential therapeutic target. Ann. Rev. Pharmacol. Toxicol. 1999, 39, 191-220.
    • (1999) Ann. Rev. Pharmacol. Toxicol. , vol.39 , pp. 191-220
    • Hobbs, A.J.1    Higgs, A.2    Moncada, S.3
  • 12
    • 0036292257 scopus 로고    scopus 로고
    • Therapeutic concentrations of propofol protects mouse macrophages from nitric oxide-induced cell death and apoptosis
    • Tsai, S.Y.; Chang, Y.; Chen, T.L.; Chen, R.M. Therapeutic concentrations of propofol protects mouse macrophages from nitric oxide-induced cell death and apoptosis. Can. J. Anesth. 2002, 49, 477-480.
    • (2002) Can. J. Anesth. , vol.49 , pp. 477-480
    • Tsai, S.Y.1    Chang, Y.2    Chen, T.L.3    Chen, R.M.4
  • 14
    • 0026569273 scopus 로고
    • Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
    • Xie, Q.W.; Cho, H.J.; Calaycay, J.; Mumford, R.A.; Swiderek, K.M.; Lee, T.D. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992, 256, 225-228.
    • (1992) Science , vol.256 , pp. 225-228
    • Xie, Q.W.1    Cho, H.J.2    Calaycay, J.3    Mumford, R.A.4    Swiderek, K.M.5    Lee, T.D.6
  • 15
    • 0035216323 scopus 로고    scopus 로고
    • Antimicrobial effect of chitooligosaccharides produced by bioreactor
    • Jeon, Y.J.; Park, P.J.; Kim, S.K. Antimicrobial effect of chitooligosaccharides produced by bioreactor. Carbohydr. Polym. 2001, 44, 71-76.
    • (2001) Carbohydr. Polym. , vol.44 , pp. 71-76
    • Jeon, Y.J.1    Park, P.J.2    Kim, S.K.3
  • 16
    • 0035889228 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
    • Kawai, T.; Takeuchi, O.; Fujita, T.; Inoue, J.; Muhlradt, P.F.; Sato, S. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J. Immunol. 2001, 167, 5887-5894.
    • (2001) J. Immunol. , vol.167 , pp. 5887-5894
    • Kawai, T.1    Takeuchi, O.2    Fujita, T.3    Inoue, J.4    Muhlradt, P.F.5    Sato, S.6
  • 17
    • 0035067108 scopus 로고    scopus 로고
    • Requirement for STAT1 in LPS-induced gene expression in macrophages
    • Ohmori, Y.; Hamilton, T.A. Requirement for STAT1 in LPS-induced gene expression in macrophages. J. Leukoc. Biol. 2001, 69, 598-604.
    • (2001) J. Leukoc. Biol. , vol.69 , pp. 598-604
    • Ohmori, Y.1    Hamilton, T.A.2
  • 18
    • 1542285373 scopus 로고    scopus 로고
    • Preparation of Hetero-Chitooligosaccharides and Their Antimicrobial Activity on Vibrio parahaemolyticus
    • Park, P.J.; Lee, H.K.; Kim, S.K. Preparation of Hetero-Chitooligosaccharides and Their Antimicrobial Activity on Vibrio parahaemolyticus. J. Microbiol. Biotechnol. 2004, 14, 41-47.
    • (2004) J. Microbiol. Biotechnol. , vol.14 , pp. 41-47
    • Park, P.J.1    Lee, H.K.2    Kim, S.K.3
  • 19
    • 0343562735 scopus 로고
    • Selective sulfonation of amino groups in amino alcohols
    • Warner, D.T.; Coleman, L.L. Selective sulfonation of amino groups in amino alcohols. J. Org. Chem. 1958, 23, 1133-1135.
    • (1958) J. Org. Chem. , vol.23 , pp. 1133-1135
    • Warner, D.T.1    Coleman, L.L.2
  • 20
    • 0015031245 scopus 로고
    • Studies on heparin degradation. I. Preparation of (35S) sulphamate derivatives for studies on heparin degrading enzymes of mammalian origin
    • Lloyd, A.G.; Embery, G.; Fowler, L.J. Studies on heparin degradation. I. Preparation of (35S) sulphamate derivatives for studies on heparin degrading enzymes of mammalian origin. Biochem. Pharmacol. 1971, 20, 637-648.
    • (1971) Biochem. Pharmacol. , vol.20 , pp. 637-648
    • Lloyd, A.G.1    Embery, G.2    Fowler, L.J.3
  • 23
    • 33748937222 scopus 로고    scopus 로고
    • Free Radicals in biology and medicine: From inflammation to biotechnology
    • Aruoma, O.I.; Grootveld, M.; Bahorun, T. Free Radicals in biology and medicine: From inflammation to biotechnology. Biofactors 2006, 27, 1-3.
    • (2006) Biofactors , vol.27 , pp. 1-3
    • Aruoma, O.I.1    Grootveld, M.2    Bahorun, T.3
  • 24
    • 70350660701 scopus 로고    scopus 로고
    • SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-κB pathways in RAW 264.7 macrophages
    • Wang, J.X.; Hou, L.F.; Yang, Y.; Tang, W.; Li, Y.; Zuo, J.P. SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-κB pathways in RAW 264.7 macrophages. Acta Pharmacol. Sin. 2009, 10, 1428-1435.
    • (2009) Acta Pharmacol. Sin. , vol.10 , pp. 1428-1435
    • Wang, J.X.1    Hou, L.F.2    Yang, Y.3    Tang, W.4    Li, Y.5    Zuo, J.P.6
  • 25
    • 77950861126 scopus 로고    scopus 로고
    • Chitosan oligosaccharides inhibit TNF-induced VCAM-1 and ICAM-1 expression in human umbilical vein endothelial cells by blocking p38 and ERK1/2 signaling pathways
    • Liu, H.T.; Li, W.M.; Huang, P.; Chen, W.J.; Liu, Q.S.; Bai, X.F.; Du, Y.G.; Yu, C. Chitosan oligosaccharides inhibit TNF-induced VCAM-1 and ICAM-1 expression in human umbilical vein endothelial cells by blocking p38 and ERK1/2 signaling pathways. Carbohydr. Polym. 2010, 81, 49-56.
    • (2010) Carbohydr. Polym. , vol.81 , pp. 49-56
    • Liu, H.T.1    Li, W.M.2    Huang, P.3    Chen, W.J.4    Liu, Q.S.5    Bai, X.F.6    Du, Y.G.7    Yu, C.8
  • 26
    • 0031897632 scopus 로고    scopus 로고
    • NF- κb and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh, S.; May, M.J.; Kopp, E.B. NF- κB and Rel proteins: Evolutionarily conserved mediators of immune responses. Ann. Rev. Immunol. 1998, 16, 225-260.
    • (1998) Ann. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 27
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan, C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 1992, 6, 3051-3064.
    • (1992) FASEB J. , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 28
    • 0034665303 scopus 로고    scopus 로고
    • Deficiency in inducible nitric oxide synthase results in reduced atherosclerosis in apolipoprotein E-deficient mice
    • Detmers, P.A.; Hernandez, M.; Mudgett, M.; Hassing, H.; Burton, C.; Mundt, S. Deficiency in inducible nitric oxide synthase results in reduced atherosclerosis in apolipoprotein E-deficient mice. J. Immunol. 2000, 165, 3430-3435.
    • (2000) J. Immunol. , vol.165 , pp. 3430-3435
    • Detmers, P.A.1    Hernandez, M.2    Mudgett, M.3    Hassing, H.4    Burton, C.5    Mundt, S.6
  • 29
    • 13244287952 scopus 로고    scopus 로고
    • Nitric oxide and cell viability in inflammatory cells: A role for NO in macrophage function and fate
    • Bosca, L.; Zeini, M.; Traves, P.G.; Hortelano, S. Nitric oxide and cell viability in inflammatory cells: A role for NO in macrophage function and fate. Toxicology 2005, 208, 249-258.
    • (2005) Toxicology , vol.208 , pp. 249-258
    • Bosca, L.1    Zeini, M.2    Traves, P.G.3    Hortelano, S.4
  • 30
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • Akira, S.; Takeda, K. Toll-like receptor signaling. Nat. Rev. Immunol. 2004, 4, 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 31
    • 33745127751 scopus 로고    scopus 로고
    • Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells
    • Chen, T.H.; Kao, Y.C.; Chen, B.C.; Chen, C.H.; Chan, P.; Lee, H.M. Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells. Eur. J. Pharmacol. 2006, 541, 138-146.
    • (2006) Eur. J. Pharmacol. , vol.541 , pp. 138-146
    • Chen, T.H.1    Kao, Y.C.2    Chen, B.C.3    Chen, C.H.4    Chan, P.5    Lee, H.M.6
  • 32
    • 80051785668 scopus 로고    scopus 로고
    • Anti-inflammatory effect of flavonoids isolated from Korea Citrus aurantium L. on lipopolysaccharide-induced mouse macrophage RAW 264.7 cells by blocking of nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) signalling pathways
    • Kang, S.R.; Park, K.I.; Park, H.S.; Lee, D.H.; Kim, J.A.; Nagappana, A.; Kim, E.H.; Lee, W.S.; Shin, S.C.; Park, M.K. Anti-inflammatory effect of flavonoids isolated from Korea Citrus aurantium L. on lipopolysaccharide-induced mouse macrophage RAW 264.7 cells by blocking of nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) signalling pathways. Food Chem. 2011, 129, 1721-1728.
    • (2011) Food Chem. , vol.129 , pp. 1721-1728
    • Kang, S.R.1    Park, K.I.2    Park, H.S.3    Lee, D.H.4    Kim, J.A.5    Nagappana, A.6    Kim, E.H.7    Lee, W.S.8    Shin, S.C.9    Park, M.K.10
  • 33
    • 0034668171 scopus 로고    scopus 로고
    • Oxidative stress interference with the nuclear factor-κB activation pathways
    • Schoonbroodt, S. Piette, Oxidative stress interference with the nuclear factor-κB activation pathways. J. Biochem. Pharmacol. 2000, 60, 1075-1083.
    • (2000) J. Biochem. Pharmacol. , vol.60 , pp. 1075-1083
    • Piette, S.S.1
  • 34
    • 79151481323 scopus 로고    scopus 로고
    • Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells
    • Ben, P.; Liu, J.; Lu, C.; Xu, Y.; Xin, Y.; Fu, J.; Huang, H.; Zhang, Z.; Gao, Y.; Luo, L.; et al. Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells. Int. Immunopharmacol. 2011, 11, 179-186.
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 179-186
    • Ben, P.1    Liu, J.2    Lu, C.3    Xu, Y.4    Xin, Y.5    Fu, J.6    Huang, H.7    Zhang, Z.8    Gao, Y.9    Luo, L.10
  • 35
    • 77953807452 scopus 로고    scopus 로고
    • Anti-inflammatory effects of methanol extracts of the root of Lilium lancifolium on LPS-stimulated Raw264.7 cells
    • Kwon, O.K.; Lee, M.Y.; Yuk, J.E.; Oh, S.R.; Chin, Y.W.; Lee, H.K.; Ahn, K.S. Anti-inflammatory effects of methanol extracts of the root of Lilium lancifolium on LPS-stimulated Raw264.7 cells. J. Ethnopharmacol. 2010, 130, 28-34.
    • (2010) J. Ethnopharmacol. , vol.130 , pp. 28-34
    • Kwon, O.K.1    Lee, M.Y.2    Yuk, J.E.3    Oh, S.R.4    Chin, Y.W.5    Lee, H.K.6    Ahn, K.S.7
  • 36
    • 80051902485 scopus 로고    scopus 로고
    • Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways
    • Su, Y.W.; Chiou, W.F.; Chao, S.H.; Lee, M.H.; Chen, C.C.; Tsai, Y.C. Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways. Int. Immunopharmacol. 2011, 11, 1166-1172.
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 1166-1172
    • Su, Y.W.1    Chiou, W.F.2    Chao, S.H.3    Lee, M.H.4    Chen, C.C.5    Tsai, Y.C.6
  • 37
    • 45449113141 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase by Acanthopanax senticosus extract in RAW264.7 macrophages
    • Lin, Q.Y.; Jin, L.J.; Cao, Z.H.; Xu, Y.P. Inhibition of inducible nitric oxide synthase by Acanthopanax senticosus extract in RAW264.7 macrophages. J. Ethnopharmacol. 2008, 118, 231-236.
    • (2008) J. Ethnopharmacol. , vol.118 , pp. 231-236
    • Lin, Q.Y.1    Jin, L.J.2    Cao, Z.H.3    Xu, Y.P.4
  • 38
    • 79960217097 scopus 로고    scopus 로고
    • Suppression of proinflammatory cytokines, iNOS, and COX-2 expression by brown algae Sargassum micracanthum in RAW264.7 macrophages
    • Yoon, W.J.; Ham, Y.M.; Kim, S.S.; Yoo, B.S.; Moon, J.Y.; Baik, J.S.; Lee, N.H.; Hyun, C.G. Suppression of proinflammatory cytokines, iNOS, and COX-2 expression by brown algae Sargassum micracanthum in RAW264.7 macrophages. Eurasian J. BioSci. 2009, 3, 130-143.
    • (2009) Eurasian J. BioSci. , vol.3 , pp. 130-143
    • Yoon, W.J.1    Ham, Y.M.2    Kim, S.S.3    Yoo, B.S.4    Moon, J.Y.5    Baik, J.S.6    Lee, N.H.7    Hyun, C.G.8
  • 39
    • 0020625894 scopus 로고
    • Flow cytometric studies of oxidative product formation by neutrophils: A graded response to membrane stimulation
    • Bass, D.A.; Parce, W.; Dechatelet, L.R.; Szejda, P.; Seeds, M.C.; Thomas, M. Flow cytometric studies of oxidative product formation by neutrophils: A graded response to membrane stimulation. J. Immunol. 1983, 30, 1910-1917.
    • (1983) J. Immunol. , vol.30 , pp. 1910-1917
    • Bass, D.A.1    Parce, W.2    Dechatelet, L.R.3    Szejda, P.4    Seeds, M.C.5    Thomas, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.