Bioinspired strategy for the ribosomal synthesis of thioether-bridged macrocyclic peptides in bacteria

ACS Chemical Biology

Volumn 9, Issue 9, 2014, Pages 2008-2013

  Bionda, Nina ^a   Cryan, Abby L ^a   Fasan, Rudi ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BRIDGED PEPTIDE; CYSTEINE; MACROCYCLIC COMPOUND; O (2 BROMOETHYL)TYROSINE; SULFIDE; THIOETHER BRIDGED MACROCYCLIC PEPTIDE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; AMINO ACID TRANSFER RNA LIGASE; CYCLOPEPTIDE; INTEIN; PEPTIDE; TYROSINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL CELL; CYCLIZATION; METHANOCALDOCOCCUS JANNASCHII; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN STRUCTURE; RIBOSOME; STOP CODON; ANALOGS AND DERIVATIVES; CHEMISTRY; ESCHERICHIA COLI; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN SYNTHESIS; SYNTHESIS;

AMINO ACID SEQUENCE; AMINO ACYL-TRNA SYNTHETASES; CYCLIZATION; CYSTEINE; ESCHERICHIA COLI; INTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PEPTIDES, CYCLIC; PROTEIN BIOSYNTHESIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SPLICING; TYROSINE;

EID: 84912531557     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500311k     Document Type: Article

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