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Volumn 36, Issue , 2014, Pages 224-231

The role of tight junctions in cancer metastasis

Author keywords

Metastasis; Tight junction; Tumour

Indexed keywords

TIGHT JUNCTION PROTEIN;

EID: 84912530586     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2014.09.008     Document Type: Review
Times cited : (101)

References (64)
  • 1
    • 77955497101 scopus 로고    scopus 로고
    • Current and emerging concepts in tumour metastasis
    • Coghlin C., Murray G.I. Current and emerging concepts in tumour metastasis. J Pathol 2010, 222(1):1-15. 10.1002/path.2727.
    • (2010) J Pathol , vol.222 , Issue.1 , pp. 1-15
    • Coghlin, C.1    Murray, G.I.2
  • 2
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse M., Fujita K., Hiiragi T., Fujimoto K., Tsukita S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 1998, 141(7):1539-1550. 10.1083/jcb.141.7.1539.
    • (1998) J Cell Biol , vol.141 , Issue.7 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.4    Tsukita, S.5
  • 3
    • 84912092373 scopus 로고    scopus 로고
    • Architecture of tight junctions and principles of molecular composition
    • Van Itallie C.M., Anderson J.M. Architecture of tight junctions and principles of molecular composition. Semin Cell Dev Biol 2014, pii: S1084-9521(14)00251-1. 10.1016/j.semcdb.08.011.
    • (2014) Semin Cell Dev Biol
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 4
    • 79951775751 scopus 로고    scopus 로고
    • Tight junction pore and leak pathways: a dynamic duo
    • Shen L., Weber C.R., Raleigh D.R., Yu D., Turner J.R. Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol 2011, 73:283-309. 10.1146/annurev-physiol-012110-142150.
    • (2011) Annu Rev Physiol , vol.73 , pp. 283-309
    • Shen, L.1    Weber, C.R.2    Raleigh, D.R.3    Yu, D.4    Turner, J.R.5
  • 5
    • 0033061321 scopus 로고    scopus 로고
    • Transmembrane proteins in the tight junction barrier
    • [PMid: 10361874]
    • Fanning A.S., Mitic L.L., Anderson J.M. Transmembrane proteins in the tight junction barrier. J Am Soc Nephrol 1999, 10(6):1337-1345. [PMid: 10361874].
    • (1999) J Am Soc Nephrol , vol.10 , Issue.6 , pp. 1337-1345
    • Fanning, A.S.1    Mitic, L.L.2    Anderson, J.M.3
  • 6
    • 0033516532 scopus 로고    scopus 로고
    • Tight junction protein ZO-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma
    • Chlenski A., Ketels K.V., Tsao M.S., Talamonti M.S., Anderson M.R., Oyasu R., et al. Tight junction protein ZO-2 is differentially expressed in normal pancreatic ducts compared to human pancreatic adenocarcinoma. Int J Cancer 1999, 82(1):37-44. 10.1002/(SICI)1097.
    • (1999) Int J Cancer , vol.82 , Issue.1 , pp. 37-44
    • Chlenski, A.1    Ketels, K.V.2    Tsao, M.S.3    Talamonti, M.S.4    Anderson, M.R.5    Oyasu, R.6
  • 7
    • 33751171327 scopus 로고    scopus 로고
    • Tight junctions and cell polarity
    • Shin K., Fogg V.C., Margolis B. Tight junctions and cell polarity. Annu Rev Cell Dev Biol 2006, 22:207-235. 10.1146/annurev.cellbio.22.010305.104219.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 207-235
    • Shin, K.1    Fogg, V.C.2    Margolis, B.3
  • 8
    • 27144466422 scopus 로고    scopus 로고
    • Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells
    • Latorre I.J., Roh M.H., Frese K.K., Weiss R.S., Margolis B., Javier R.T. Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells. J Cell Sci 2005, 118(Pt 18):4283-4293. 10.1242/jcs.02560.
    • (2005) J Cell Sci , vol.118 , pp. 4283-4293
    • Latorre, I.J.1    Roh, M.H.2    Frese, K.K.3    Weiss, R.S.4    Margolis, B.5    Javier, R.T.6
  • 9
    • 0016430104 scopus 로고
    • Combination versus single agent chemotherapy, a review of the basis for selection of drug treatment of cancer
    • Devita V.T., Young R.C., Canellos G.P. Combination versus single agent chemotherapy, a review of the basis for selection of drug treatment of cancer. Cancer 1975, 35:98-110.
    • (1975) Cancer , vol.35 , pp. 98-110
    • Devita, V.T.1    Young, R.C.2    Canellos, G.P.3
  • 10
    • 0030056112 scopus 로고    scopus 로고
    • Cell adhesion molecules in angiogenesis
    • Brooks P.C. Cell adhesion molecules in angiogenesis. Can Met Rev 1996, 15:187-194.
    • (1996) Can Met Rev , vol.15 , pp. 187-194
    • Brooks, P.C.1
  • 11
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J., Shing Y. Angiogenesis. J Biol Chem 1992, 267:10931-10934.
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 12
    • 0030242225 scopus 로고    scopus 로고
    • Fighting cancer by attacking its blood supply
    • Folkman J. Fighting cancer by attacking its blood supply. Sci Am 1996, 275:150-151.
    • (1996) Sci Am , vol.275 , pp. 150-151
    • Folkman, J.1
  • 13
    • 0033022420 scopus 로고    scopus 로고
    • Biological implications of macrophage infiltration in human tumor angiogenesis
    • Ono M., Torisu H., Fukushi H.J., Nishie A., Kuwana M. Biological implications of macrophage infiltration in human tumor angiogenesis. Can Chem Pharm 1999, 43:S69-S71.
    • (1999) Can Chem Pharm , vol.43 , pp. S69-S71
    • Ono, M.1    Torisu, H.2    Fukushi, H.J.3    Nishie, A.4    Kuwana, M.5
  • 14
    • 63249115113 scopus 로고    scopus 로고
    • Loss of tight junction barrier function and its role in cancer metastasis
    • Martin T.A., Jiang W.G. Loss of tight junction barrier function and its role in cancer metastasis. Biochim Biophys Acta 2009, 1788(4):872-891. 10.1016/j.bbamem.2008.
    • (2009) Biochim Biophys Acta , vol.1788 , Issue.4 , pp. 872-891
    • Martin, T.A.1    Jiang, W.G.2
  • 15
    • 0036320972 scopus 로고    scopus 로고
    • Antagonistic effect of NK4 on HGF/SF induced changes in the transendothelial resistance (TER) and paracellular permeability of human vascular endothelial cells
    • Martin T.A., Mansel R.E., Jiang W.G. Antagonistic effect of NK4 on HGF/SF induced changes in the transendothelial resistance (TER) and paracellular permeability of human vascular endothelial cells. J Cell Physiol 2002, 192(3):268-275. 10.1002/jcp.10133.
    • (2002) J Cell Physiol , vol.192 , Issue.3 , pp. 268-275
    • Martin, T.A.1    Mansel, R.E.2    Jiang, W.G.3
  • 16
    • 0036197421 scopus 로고    scopus 로고
    • Expression and targeting of the tight junction protein CLDN1 in CLDN1-negative human breast tumor cells
    • Hoevel T., Macek R., Mundigl O., Swisshelm K., Kubbies M. Expression and targeting of the tight junction protein CLDN1 in CLDN1-negative human breast tumor cells. J Cell Physiol 2002, 191(1):60-68. 10.1002/jcp.10076.
    • (2002) J Cell Physiol , vol.191 , Issue.1 , pp. 60-68
    • Hoevel, T.1    Macek, R.2    Mundigl, O.3    Swisshelm, K.4    Kubbies, M.5
  • 17
    • 0025021876 scopus 로고
    • Ultrastructural differences in junctional intercellular communication between highly and weakly metastatic clones derived from rat mammary carcinoma
    • [PMid: 2295075]
    • Ren J., Hamada J., Takeichi N., Fujikawa S., Kobayashi H. Ultrastructural differences in junctional intercellular communication between highly and weakly metastatic clones derived from rat mammary carcinoma. Cancer Res 1990, 50(2):358-362. [PMid: 2295075].
    • (1990) Cancer Res , vol.50 , Issue.2 , pp. 358-362
    • Ren, J.1    Hamada, J.2    Takeichi, N.3    Fujikawa, S.4    Kobayashi, H.5
  • 18
    • 0030027609 scopus 로고    scopus 로고
    • Localization of 7H6 tight junction-associated antigen along the cell border of vascular endothelial cells correlates with paracellular barrier function against ions, large molecules, and cancer cells
    • Satoh H., Zhong Y., Isomura H., Saitoh M., Enomoto K., Sawada N., et al. Localization of 7H6 tight junction-associated antigen along the cell border of vascular endothelial cells correlates with paracellular barrier function against ions, large molecules, and cancer cells. Exp Cell Res 1996, 222(2):269-274. 10.1006/excr.1996.0034.
    • (1996) Exp Cell Res , vol.222 , Issue.2 , pp. 269-274
    • Satoh, H.1    Zhong, Y.2    Isomura, H.3    Saitoh, M.4    Enomoto, K.5    Sawada, N.6
  • 19
    • 0014804858 scopus 로고
    • Ultrastructural modifications of intercellular junctions in some epithelial tumors
    • Martinez-Paloma A. Ultrastructural modifications of intercellular junctions in some epithelial tumors. Lab Invest 1970, 22(6):9.
    • (1970) Lab Invest , vol.22 , Issue.6 , pp. 9
    • Martinez-Paloma, A.1
  • 20
    • 0021187560 scopus 로고
    • Acinic cell carcinoma arising in the glossopalatine glands: a report of two cases with electron microscopic observations
    • Inoue T., Shimono M., Yamamura T., Saito I., Watanabe O., Kawahara H. Acinic cell carcinoma arising in the glossopalatine glands: a report of two cases with electron microscopic observations. Oral Surg Oral Med Oral Pathol 1984, 57(4):398-407. 10.1016/0030-4220(84)90159-2.
    • (1984) Oral Surg Oral Med Oral Pathol , vol.57 , Issue.4 , pp. 398-407
    • Inoue, T.1    Shimono, M.2    Yamamura, T.3    Saito, I.4    Watanabe, O.5    Kawahara, H.6
  • 21
    • 0022970053 scopus 로고
    • Effects of tumor promoters on LLC-PK1 renal epithelial tight junctions and transepithelial fluxes
    • Mullin J.M., O'Brien T.G. Effects of tumor promoters on LLC-PK1 renal epithelial tight junctions and transepithelial fluxes. Am J Physiol 1986, 251(4 (Pt 1)):C597-C602.
    • (1986) Am J Physiol , vol.251 , Issue.4 , pp. C597-C602
    • Mullin, J.M.1    O'Brien, T.G.2
  • 22
    • 0031695576 scopus 로고    scopus 로고
    • Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion
    • Gopalakrishnan S., Raman N., Atkinson S.J., Marrs J.A. Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion. Am J Physiol 1998, 275(3 (Pt 1)):C798-C809.
    • (1998) Am J Physiol , vol.275 , Issue.3 , pp. C798-C809
    • Gopalakrishnan, S.1    Raman, N.2    Atkinson, S.J.3    Marrs, J.A.4
  • 23
    • 0024337869 scopus 로고
    • Molecular aspects of the metastatic cascade
    • [PMid: 2665818]
    • Hart I.R., Goode N.T., Wilson R.E. Molecular aspects of the metastatic cascade. Biochim Biophys Acta 1989, 989(1):65-84. [PMid: 2665818].
    • (1989) Biochim Biophys Acta , vol.989 , Issue.1 , pp. 65-84
    • Hart, I.R.1    Goode, N.T.2    Wilson, R.E.3
  • 24
    • 0028110416 scopus 로고
    • Molecular and cellular basis of cancer invasion and metastasis: implications for treatment
    • Jiang W.G., Puntis M.C., Hallett M.B. Molecular and cellular basis of cancer invasion and metastasis: implications for treatment. Br J Surg 1994, 81(11):1576-1590. 10.1002/bjs.1800811107.
    • (1994) Br J Surg , vol.81 , Issue.11 , pp. 1576-1590
    • Jiang, W.G.1    Puntis, M.C.2    Hallett, M.B.3
  • 25
    • 0030026476 scopus 로고    scopus 로고
    • Effect of tumour cell-conditioned medium on endothelial macromolecular permeability and its correlation with collagen
    • [PMid: 8554978]
    • Utoguchi N., Mizuguchi H., Dantakean A., Makimoto H., Wakai Y., Tsutsumi Y., et al. Effect of tumour cell-conditioned medium on endothelial macromolecular permeability and its correlation with collagen. Br J Cancer 1996, 73(1):24-28. [PMid: 8554978].
    • (1996) Br J Cancer , vol.73 , Issue.1 , pp. 24-28
    • Utoguchi, N.1    Mizuguchi, H.2    Dantakean, A.3    Makimoto, H.4    Wakai, Y.5    Tsutsumi, Y.6
  • 26
    • 0032862259 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor decreases the expression of occludin and transendothelial resistance (TER) and increases paracellular permeability in human vascular endothelial cells
    • Jiang W.G., Martin T.A., Matsumoto K., Nakamura T., Mansel R.E. Hepatocyte growth factor/scatter factor decreases the expression of occludin and transendothelial resistance (TER) and increases paracellular permeability in human vascular endothelial cells. J Cell Physiol 1999, 181(2):319-329. 10.1002/(SICI)1097-4652(199911)181:2<319::AID-JCP14>3.0.CO;2-S.
    • (1999) J Cell Physiol , vol.181 , Issue.2 , pp. 319-329
    • Jiang, W.G.1    Martin, T.A.2    Matsumoto, K.3    Nakamura, T.4    Mansel, R.E.5
  • 27
    • 33947281787 scopus 로고    scopus 로고
    • Increased ICAM-1 expression causes endothelial cell leakiness, cytoskeletal reorganization and junctional alterations
    • Clark P.R., Manes T.D., Pober J.S., Kluger M.S. Increased ICAM-1 expression causes endothelial cell leakiness, cytoskeletal reorganization and junctional alterations. J Invest Dermatol 2007, 127(4):762-774. 10.1038/sj.jid.5700670.
    • (2007) J Invest Dermatol , vol.127 , Issue.4 , pp. 762-774
    • Clark, P.R.1    Manes, T.D.2    Pober, J.S.3    Kluger, M.S.4
  • 28
    • 84904428205 scopus 로고    scopus 로고
    • Role of MMP-9 in the breakdown of barrier integrity of the corneal endothelium in response to TNF-alpha
    • Rajashekhar G., Shivanna M., Kompella U.B., Wang Y., Srinivas S.P. Role of MMP-9 in the breakdown of barrier integrity of the corneal endothelium in response to TNF-alpha. Exp Eye Res 2014, 122:77-85. 10.1016/j.exer.2014.03.004.
    • (2014) Exp Eye Res , vol.122 , pp. 77-85
    • Rajashekhar, G.1    Shivanna, M.2    Kompella, U.B.3    Wang, Y.4    Srinivas, S.P.5
  • 29
    • 84898476721 scopus 로고    scopus 로고
    • Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis
    • Zhou W., Fong M.Y., Min Y., Somlo G., Liu L., Palomares M.R., et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell 2014, 25(4):501-515. 10.1016/j.ccr.2014.03.007.
    • (2014) Cancer Cell , vol.25 , Issue.4 , pp. 501-515
    • Zhou, W.1    Fong, M.Y.2    Min, Y.3    Somlo, G.4    Liu, L.5    Palomares, M.R.6
  • 30
    • 84897576094 scopus 로고    scopus 로고
    • Permeability of the blood-tumor barrier is enhanced by combining vascular endothelial growth factor with papaverine
    • Yang Z.H., Liu L.B., Zhao L.N., Liu Y.H., Xue Y.X. Permeability of the blood-tumor barrier is enhanced by combining vascular endothelial growth factor with papaverine. J Neurosci Res 2014, 92(6):703-713. 10.1002/jnr.23348.
    • (2014) J Neurosci Res , vol.92 , Issue.6 , pp. 703-713
    • Yang, Z.H.1    Liu, L.B.2    Zhao, L.N.3    Liu, Y.H.4    Xue, Y.X.5
  • 31
    • 84896509261 scopus 로고    scopus 로고
    • Krüppel-like factor 4 regulates blood-tumor barrier permeability via ZO-1, occludin and claudin-5
    • Ma J., Wang P., Liu Y., Zhao L., Li Z., Xue Y. Krüppel-like factor 4 regulates blood-tumor barrier permeability via ZO-1, occludin and claudin-5. J Cell Physiol 2014, 229(7):916-926. 10.1002/jcp.24523.
    • (2014) J Cell Physiol , vol.229 , Issue.7 , pp. 916-926
    • Ma, J.1    Wang, P.2    Liu, Y.3    Zhao, L.4    Li, Z.5    Xue, Y.6
  • 32
    • 84877644960 scopus 로고    scopus 로고
    • Stromal Claudin 14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth
    • Baker M., Reynolds L.E., Robinson S.D., Lees D.M., Parsons M., Elia G., et al. Stromal Claudin 14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth. PLOS ONE 2013, 8(5):e62516. 10.1371/journal.pone.0062516.
    • (2013) PLOS ONE , vol.8 , Issue.5 , pp. e62516
    • Baker, M.1    Reynolds, L.E.2    Robinson, S.D.3    Lees, D.M.4    Parsons, M.5    Elia, G.6
  • 33
    • 84865680246 scopus 로고    scopus 로고
    • VEGF induces ascites in ovarian cancer patients via increasing peritoneal permeability by downregulation of Claudin 5
    • Herr D., Sallmann A., Bekes I., Konrad R., Holzheu I., Kreienberg R., et al. VEGF induces ascites in ovarian cancer patients via increasing peritoneal permeability by downregulation of Claudin 5. Gynecol Oncol 2012, 127(1):210-216. 10.1016/j.ygyno.2012.05.002.
    • (2012) Gynecol Oncol , vol.127 , Issue.1 , pp. 210-216
    • Herr, D.1    Sallmann, A.2    Bekes, I.3    Konrad, R.4    Holzheu, I.5    Kreienberg, R.6
  • 34
    • 0037417428 scopus 로고    scopus 로고
    • Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast
    • Kominsky S.L., Argani P., Korz D., Evron E., Raman V., Garrett E., et al. Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast. Oncogene 2003, 22(13):2021-2033. 10.1038/sj.onc.1206199.
    • (2003) Oncogene , vol.22 , Issue.13 , pp. 2021-2033
    • Kominsky, S.L.1    Argani, P.2    Korz, D.3    Evron, E.4    Raman, V.5    Garrett, E.6
  • 35
    • 0030016641 scopus 로고    scopus 로고
    • Enhanced paracellular barrier function of rat mesothelial cells partially protects against cancer cell penetration
    • Tobioka H., Sawada N., Zhong Y., Mori M. Enhanced paracellular barrier function of rat mesothelial cells partially protects against cancer cell penetration. Br J Cancer 1996, 74(3):439-445.
    • (1996) Br J Cancer , vol.74 , Issue.3 , pp. 439-445
    • Tobioka, H.1    Sawada, N.2    Zhong, Y.3    Mori, M.4
  • 36
    • 84903310187 scopus 로고    scopus 로고
    • Tumour cell invasion: an emerging role for basal epithelial cell extrusion
    • Slattum G.M., Jody R. Tumour cell invasion: an emerging role for basal epithelial cell extrusion. Nat Rev Can 2014, 14:495-501. 10.1038/nrc3767.
    • (2014) Nat Rev Can , vol.14 , pp. 495-501
    • Slattum, G.M.1    Jody, R.2
  • 37
    • 34248143390 scopus 로고    scopus 로고
    • The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation
    • Stucke V.M., Timmerman E., Vandekerckhove J., Gevaert J.K., Hall A. The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation. Mol Biol Cell 2007, 18(5):1744-1755. 10.1091/mbc.E06-11-0980.
    • (2007) Mol Biol Cell , vol.18 , Issue.5 , pp. 1744-1755
    • Stucke, V.M.1    Timmerman, E.2    Vandekerckhove, J.3    Gevaert, J.K.4    Hall, A.5
  • 38
    • 28644445404 scopus 로고    scopus 로고
    • Ras mutation impairs epithelial barrier function to a wide range of nonelectrolytes
    • Mullin J.M., Leatherman J.M., Valenzano M.C., Huerta E.R., Verrechio J., Smith D.M., et al. Ras mutation impairs epithelial barrier function to a wide range of nonelectrolytes. Mol Biol Cell 2005, 16(12):5538-5550. 10.1091/mbc.E05-04-0294.
    • (2005) Mol Biol Cell , vol.16 , Issue.12 , pp. 5538-5550
    • Mullin, J.M.1    Leatherman, J.M.2    Valenzano, M.C.3    Huerta, E.R.4    Verrechio, J.5    Smith, D.M.6
  • 39
    • 0032820577 scopus 로고    scopus 로고
    • Increased tight junctional permeability is associated with the development of colon cancer
    • Soler A.P., Miller R.D., Laughlin K.V., Carp N.Z., Klurfeld D.M., Mullin J.M. Increased tight junctional permeability is associated with the development of colon cancer. Carcinogenesis 1999, 20(8):1425-1431. 10.1093/carcin/20.8.1425.
    • (1999) Carcinogenesis , vol.20 , Issue.8 , pp. 1425-1431
    • Soler, A.P.1    Miller, R.D.2    Laughlin, K.V.3    Carp, N.Z.4    Klurfeld, D.M.5    Mullin, J.M.6
  • 40
    • 0034522427 scopus 로고    scopus 로고
    • Increased tight junction permeability can result from protein kinase C activation/translocation and act as a tumor promotional event in epithelial cancers
    • [PMid: 11193580]
    • Mullin J.M., Laughlin K.V., Ginanni N., Marano W., Clarke H.M., Peralta Soler A. Increased tight junction permeability can result from protein kinase C activation/translocation and act as a tumor promotional event in epithelial cancers. Ann N Y Acad Sci 2000, 915:231-236. [PMid: 11193580].
    • (2000) Ann N Y Acad Sci , vol.915 , pp. 231-236
    • Mullin, J.M.1    Laughlin, K.V.2    Ginanni, N.3    Marano, W.4    Clarke, H.M.5    Peralta Soler, A.6
  • 41
    • 0033783241 scopus 로고    scopus 로고
    • Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets
    • [PMid: 10954417]
    • Clarke H., Soler A.P., Mullin J.M. Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets. J Cell Sci 2000, 113(Pt 18):3187-3196. [PMid: 10954417].
    • (2000) J Cell Sci , vol.113 , pp. 3187-3196
    • Clarke, H.1    Soler, A.P.2    Mullin, J.M.3
  • 42
    • 2942571778 scopus 로고    scopus 로고
    • Hepatocyte growth factor disrupts tight junctions in human breast cancer cells
    • Martin T.A., Watkins G., Mansel R.E., Jiang W.G. Hepatocyte growth factor disrupts tight junctions in human breast cancer cells. Cell Biol Int 2004, 28(5):361-371. 10.1016/j.cellbi.2004.03.003.
    • (2004) Cell Biol Int , vol.28 , Issue.5 , pp. 361-371
    • Martin, T.A.1    Watkins, G.2    Mansel, R.E.3    Jiang, W.G.4
  • 43
    • 0036652193 scopus 로고    scopus 로고
    • Culture and co-culture of DU145 prostate carcinoma, osteoblasts and HT-29 colon carcinoma cells on a fabricated type III collagen matrix
    • Macias C.L., Williams K., Baccetti B., Renieri T., Reddi H., Asseffa A., et al. Culture and co-culture of DU145 prostate carcinoma, osteoblasts and HT-29 colon carcinoma cells on a fabricated type III collagen matrix. J Submicrosc Cytol Pathol 2002, 34(3):241-253.
    • (2002) J Submicrosc Cytol Pathol , vol.34 , Issue.3 , pp. 241-253
    • Macias, C.L.1    Williams, K.2    Baccetti, B.3    Renieri, T.4    Reddi, H.5    Asseffa, A.6
  • 44
    • 84903286833 scopus 로고    scopus 로고
    • Emerging multifunctional roles of Claudin tight junction proteins in bone
    • Alshbool F.Z., Mohan S. Emerging multifunctional roles of Claudin tight junction proteins in bone. Endocrinology 2014, 155(7):2363-2376. 10.1210/en.2014-1173.
    • (2014) Endocrinology , vol.155 , Issue.7 , pp. 2363-2376
    • Alshbool, F.Z.1    Mohan, S.2
  • 45
    • 11144237716 scopus 로고    scopus 로고
    • Osteoblasts in prostate cancer metastasis to bone
    • Logothetis C.J., Lin S.H. Osteoblasts in prostate cancer metastasis to bone. Nat Rev Can 2005, 5:21-28. 10.1038/nrc1528.
    • (2005) Nat Rev Can , vol.5 , pp. 21-28
    • Logothetis, C.J.1    Lin, S.H.2
  • 46
    • 80052575583 scopus 로고    scopus 로고
    • Breast cancer metastasis to the bone: mechanisms of bone loss
    • Chen Y.C., Sosnoski D.M., Mastro A.M. Breast cancer metastasis to the bone: mechanisms of bone loss. Breast Cancer Res 2010, 12:215. 10.1186/bcr2781.
    • (2010) Breast Cancer Res , vol.12 , pp. 215
    • Chen, Y.C.1    Sosnoski, D.M.2    Mastro, A.M.3
  • 47
    • 10944258685 scopus 로고    scopus 로고
    • Claudins 2, 3, 4, and 5 in Paget's disease and breast carcinoma
    • Soini Y. Claudins 2, 3, 4, and 5 in Paget's disease and breast carcinoma. Hum Pathol 2004, 35(12):1531-1536.
    • (2004) Hum Pathol , vol.35 , Issue.12 , pp. 1531-1536
    • Soini, Y.1
  • 48
    • 0035503028 scopus 로고    scopus 로고
    • Expression of Clostridium perfringens enterotoxin receptors claudin-3 and claudin-4 in prostate cancer epithelium
    • [PMid: 11691807]
    • Long H., Crean C.D., Lee W.H., Cummings O.W., Gabig T.G. Expression of Clostridium perfringens enterotoxin receptors claudin-3 and claudin-4 in prostate cancer epithelium. Cancer Res 2001, 61(21):7878-7881. [PMid: 11691807].
    • (2001) Cancer Res , vol.61 , Issue.21 , pp. 7878-7881
    • Long, H.1    Crean, C.D.2    Lee, W.H.3    Cummings, O.W.4    Gabig, T.G.5
  • 49
    • 84881332287 scopus 로고    scopus 로고
    • Junctional adhesion molecules in cerebral endothelial tight junction and brain metastasis
    • Jia W., Martin T.A., Zhang G., Jiang W.G. Junctional adhesion molecules in cerebral endothelial tight junction and brain metastasis. Anticancer Res 2013, 33(6):2353-2359.
    • (2013) Anticancer Res , vol.33 , Issue.6 , pp. 2353-2359
    • Jia, W.1    Martin, T.A.2    Zhang, G.3    Jiang, W.G.4
  • 50
    • 0020965779 scopus 로고
    • Blood-brain barrier integrity and host responses in experimental metastatic brain tumours
    • Greig N.H., Jones H.B., Cavanagh J.B. Blood-brain barrier integrity and host responses in experimental metastatic brain tumours. Clin Exp Metastasis 1983, 1(3):229-246.
    • (1983) Clin Exp Metastasis , vol.1 , Issue.3 , pp. 229-246
    • Greig, N.H.1    Jones, H.B.2    Cavanagh, J.B.3
  • 51
    • 0036976431 scopus 로고    scopus 로고
    • Chemotherapy for breast cancer brain metastases
    • Fenner M.H., Possinger K. Chemotherapy for breast cancer brain metastases. Onkologie 2002, 25(5):474-479.
    • (2002) Onkologie , vol.25 , Issue.5 , pp. 474-479
    • Fenner, M.H.1    Possinger, K.2
  • 52
    • 77951682279 scopus 로고    scopus 로고
    • Polychlorinated biphenyls disrupt blood-brain barrier integrity and promote brain metastasis formation
    • Seelbach M., Chen L., Powell A., Choi Y.J., Zhang B., Hennig B., et al. Polychlorinated biphenyls disrupt blood-brain barrier integrity and promote brain metastasis formation. Environ Health Perspect 2010, 118(4):479-484. 10.1289/ehp.0901334.
    • (2010) Environ Health Perspect , vol.118 , Issue.4 , pp. 479-484
    • Seelbach, M.1    Chen, L.2    Powell, A.3    Choi, Y.J.4    Zhang, B.5    Hennig, B.6
  • 53
    • 84908118492 scopus 로고    scopus 로고
    • Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
    • Sevenich L., Bowman R.L., Mason S.D., Quail D.F., Rapaport F., Elie B.T., et al. Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S. Nat Cell Biol 2014, 10.1038/ncb3011.
    • (2014) Nat Cell Biol
    • Sevenich, L.1    Bowman, R.L.2    Mason, S.D.3    Quail, D.F.4    Rapaport, F.5    Elie, B.T.6
  • 54
    • 79957976779 scopus 로고    scopus 로고
    • Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases
    • Fazakas C., Wilhelm I., Nagyoszi P., Farkas A.E., Haskó J., Molnár J., et al. Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases. PLoS ONE 2011, 6(6):e20758. 10.1371/journal.pone.0020758.
    • (2011) PLoS ONE , vol.6 , Issue.6 , pp. e20758
    • Fazakas, C.1    Wilhelm, I.2    Nagyoszi, P.3    Farkas, A.E.4    Haskó, J.5    Molnár, J.6
  • 55
    • 80051709700 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins
    • Feng S., Cen J., Huang Y., Shen H., Yao L., Wang Y., et al. Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins. PLoS ONE 2011, 6(8):e20599. 10.1371/journal.pone.0020599.
    • (2011) PLoS ONE , vol.6 , Issue.8 , pp. e20599
    • Feng, S.1    Cen, J.2    Huang, Y.3    Shen, H.4    Yao, L.5    Wang, Y.6
  • 56
    • 84879416014 scopus 로고    scopus 로고
    • Elevated PLGF contributes to small-cell lung cancer brain metastasis
    • Li B., Wang C., Zhang Y., Zhao X.Y., Huang B., Wu P.F., et al. Elevated PLGF contributes to small-cell lung cancer brain metastasis. Oncogene 2013, 32(24):2952-2962. 10.1038/onc.2012.313.
    • (2013) Oncogene , vol.32 , Issue.24 , pp. 2952-2962
    • Li, B.1    Wang, C.2    Zhang, Y.3    Zhao, X.Y.4    Huang, B.5    Wu, P.F.6
  • 57
    • 84900319732 scopus 로고    scopus 로고
    • Novel pharmacologic targeting of tight junctions and focal adhesions in prostate cancer cells
    • Hensley P.J., Desiniotis A., Wang C., Stromberg A., Chen C.S., Kyprianou N. Novel pharmacologic targeting of tight junctions and focal adhesions in prostate cancer cells. PLOS ONE 2014, 9(1):e86238. 10.1371/journal.pone.0086238.
    • (2014) PLOS ONE , vol.9 , Issue.1 , pp. e86238
    • Hensley, P.J.1    Desiniotis, A.2    Wang, C.3    Stromberg, A.4    Chen, C.S.5    Kyprianou, N.6
  • 58
    • 84892381025 scopus 로고    scopus 로고
    • Angiopoietin-2 mediates blood-brain barrier impairment and colonization of triple-negative breast cancer cells in brain
    • Avraham H.K., Jiang S., Fu Y., Nakshatri H., Ovadia H., Avraham S. Angiopoietin-2 mediates blood-brain barrier impairment and colonization of triple-negative breast cancer cells in brain. J Pathol 2014, 232(3):369-381. 10.1002/path.4304.
    • (2014) J Pathol , vol.232 , Issue.3 , pp. 369-381
    • Avraham, H.K.1    Jiang, S.2    Fu, Y.3    Nakshatri, H.4    Ovadia, H.5    Avraham, S.6
  • 59
    • 84877049950 scopus 로고    scopus 로고
    • Inhibition of SUR1 decreases the vascular permeability of cerebral metastases
    • Thompson E.M., Pishko G.L., Muldoon L.L., Neuwelt E.A. Inhibition of SUR1 decreases the vascular permeability of cerebral metastases. Neoplasia 2013, 15(5):535-543.
    • (2013) Neoplasia , vol.15 , Issue.5 , pp. 535-543
    • Thompson, E.M.1    Pishko, G.L.2    Muldoon, L.L.3    Neuwelt, E.A.4
  • 60
    • 76649121522 scopus 로고    scopus 로고
    • The ethyl alcohol extract of Hizikia fusiforme inhibits matrix metalloproteinase activity and regulates tight junction related protein expression in Hep3B human hepatocarcinoma cells
    • Kim S.O., Choi Y.H. The ethyl alcohol extract of Hizikia fusiforme inhibits matrix metalloproteinase activity and regulates tight junction related protein expression in Hep3B human hepatocarcinoma cells. J Med Food 2010, 13(1):31-38. 10.1089/jmf.2009.1233.
    • (2010) J Med Food , vol.13 , Issue.1 , pp. 31-38
    • Kim, S.O.1    Choi, Y.H.2
  • 61
    • 66449120262 scopus 로고    scopus 로고
    • Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis
    • Shah G.V., Muralidharan A., Thomas S., Gokulgandhi M., Mudit M., Khanfar M., et al. Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis. Mol Cancer Ther 2009, 8(3):509-520. 10.1158/1535-7163.MCT-08-0693.
    • (2009) Mol Cancer Ther , vol.8 , Issue.3 , pp. 509-520
    • Shah, G.V.1    Muralidharan, A.2    Thomas, S.3    Gokulgandhi, M.4    Mudit, M.5    Khanfar, M.6
  • 62
    • 84890553647 scopus 로고    scopus 로고
    • The proinflammatory peptide substance P promotes blood-brain barrier breaching by breast cancer cells through changes in microvascular endothelial cell tight junctions
    • Rodriguez P.L., Jiang S., Fu Y., Avraham S., Avraham H.K. The proinflammatory peptide substance P promotes blood-brain barrier breaching by breast cancer cells through changes in microvascular endothelial cell tight junctions. Int J Cancer 2014, 134(5):1034-1044. 10.1002/ijc.28433.
    • (2014) Int J Cancer , vol.134 , Issue.5 , pp. 1034-1044
    • Rodriguez, P.L.1    Jiang, S.2    Fu, Y.3    Avraham, S.4    Avraham, H.K.5
  • 63
    • 77952958787 scopus 로고    scopus 로고
    • Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin
    • Kakutani H., Kondoh M., Saeki R., Fujii M., Watanabe Y., Mizuguchi H., et al. Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin. Eur J Pharm Biopharm 2010, 5(2):213-217. 10.1016/j.ejpb.2010.03.003.
    • (2010) Eur J Pharm Biopharm , vol.5 , Issue.2 , pp. 213-217
    • Kakutani, H.1    Kondoh, M.2    Saeki, R.3    Fujii, M.4    Watanabe, Y.5    Mizuguchi, H.6
  • 64
    • 61449562121 scopus 로고    scopus 로고
    • Claudin expression in rectal well-differentiated endocrine neoplasms (carcinoid tumors)
    • [PMid: 19082451]
    • Ishida M., Kushima R., Okabe H. Claudin expression in rectal well-differentiated endocrine neoplasms (carcinoid tumors). Oncol Rep 2009, 21(1):113-117. [PMid: 19082451].
    • (2009) Oncol Rep , vol.21 , Issue.1 , pp. 113-117
    • Ishida, M.1    Kushima, R.2    Okabe, H.3


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